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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)
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Results for KLF14_SP8
Z-value: 1.41
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Transcription factors associated with KLF14_SP8
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| SP8 | hg19_v2_chr7_-_20826504_20826526 | 0.81 | 1.9e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr4_+_76649753 Show fit | 1.49 |
ENST00000603759.1
|
USO1 vesicle transport factor |
|
| chr1_+_228362251 Show fit | 1.48 |
ENST00000546123.1
|
IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) |
|
| chr19_+_42773371 Show fit | 1.03 |
ENST00000571942.2
|
capicua transcriptional repressor |
|
| chr19_+_47778119 Show fit | 1.00 |
ENST00000552360.2
|
proline rich 24 |
|
| chr6_-_33285505 Show fit | 0.99 |
ENST00000431845.2
|
zinc finger and BTB domain containing 22 |
|
| chr5_-_180237082 Show fit | 0.97 |
ENST00000506889.1
|
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
|
| chr19_-_38878632 Show fit | 0.92 |
ENST00000586599.1
ENST00000334928.6 ENST00000587676.1 |
gametogenetin |
|
| chr19_-_1863567 Show fit | 0.87 |
ENST00000250916.4
|
Kruppel-like factor 16 |
|
| chr9_+_130922537 Show fit | 0.73 |
ENST00000372994.1
|
chromosome 9 open reading frame 16 |
|
| chr2_+_64068116 Show fit | 0.73 |
ENST00000480679.1
|
UDP-glucose pyrophosphorylase 2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of KLF14_SP8
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.8 | GO:0006049 | UDP-N-acetylglucosamine catabolic process(GO:0006049) |
| 0.1 | 1.7 | GO:0031163 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
| 0.1 | 1.4 | GO:0006527 | arginine catabolic process(GO:0006527) |
| 0.1 | 1.3 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
| 0.0 | 1.1 | GO:0045736 | negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) |
| 0.2 | 1.0 | GO:0006050 | mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051) |
| 0.0 | 1.0 | GO:0045600 | positive regulation of fat cell differentiation(GO:0045600) |
| 0.1 | 0.9 | GO:0070294 | renal sodium ion absorption(GO:0070294) |
| 0.3 | 0.8 | GO:0043095 | regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105) |
| 0.2 | 0.8 | GO:0021849 | neuroblast division in subventricular zone(GO:0021849) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.5 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
| 0.0 | 1.0 | GO:0030286 | dynein complex(GO:0030286) |
| 0.1 | 0.8 | GO:0030896 | checkpoint clamp complex(GO:0030896) |
| 0.0 | 0.8 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
| 0.1 | 0.7 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
| 0.1 | 0.6 | GO:0000214 | tRNA-intron endonuclease complex(GO:0000214) |
| 0.0 | 0.6 | GO:0031932 | TORC2 complex(GO:0031932) |
| 0.0 | 0.6 | GO:0031258 | lamellipodium membrane(GO:0031258) |
| 0.1 | 0.5 | GO:0005587 | collagen type IV trimer(GO:0005587) |
| 0.0 | 0.5 | GO:0070765 | gamma-secretase complex(GO:0070765) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.8 | GO:0003827 | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827) |
| 0.1 | 1.6 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
| 0.2 | 1.4 | GO:0016403 | dimethylargininase activity(GO:0016403) |
| 0.1 | 1.1 | GO:0030976 | thiamine pyrophosphate binding(GO:0030976) |
| 0.0 | 1.1 | GO:0030145 | manganese ion binding(GO:0030145) |
| 0.2 | 1.0 | GO:0045127 | N-acetylglucosamine kinase activity(GO:0045127) |
| 0.3 | 0.8 | GO:0044549 | GTP cyclohydrolase binding(GO:0044549) |
| 0.1 | 0.7 | GO:0019770 | IgG receptor activity(GO:0019770) |
| 0.1 | 0.7 | GO:0005052 | peroxisome matrix targeting signal-1 binding(GO:0005052) |
| 0.1 | 0.7 | GO:0015450 | P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.3 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.0 | 1.3 | PID PDGFRA PATHWAY | PDGFR-alpha signaling pathway |
| 0.0 | 0.8 | ST GAQ PATHWAY | G alpha q Pathway |
| 0.0 | 0.7 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.0 | 0.6 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.0 | 0.6 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.0 | 0.5 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.0 | 0.5 | PID ECADHERIN KERATINOCYTE PATHWAY | E-cadherin signaling in keratinocytes |
| 0.0 | 0.4 | ST PAC1 RECEPTOR PATHWAY | PAC1 Receptor Pathway |
| 0.0 | 0.4 | PID RET PATHWAY | Signaling events regulated by Ret tyrosine kinase |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.0 | REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
| 0.0 | 1.1 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.0 | 0.7 | REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
| 0.0 | 0.7 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.0 | 0.6 | REACTOME ACYL CHAIN REMODELLING OF PI | Genes involved in Acyl chain remodelling of PI |
| 0.0 | 0.6 | REACTOME SIGNALING BY NOTCH3 | Genes involved in Signaling by NOTCH3 |
| 0.0 | 0.5 | REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS | Genes involved in Elevation of cytosolic Ca2+ levels |
| 0.0 | 0.5 | REACTOME IRAK1 RECRUITS IKK COMPLEX | Genes involved in IRAK1 recruits IKK complex |
| 0.0 | 0.5 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.0 | 0.5 | REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |