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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)
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Results for KLF13
Z-value: 1.04
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Transcription factors associated with KLF13
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| KLF13 | hg19_v2_chr15_+_31619013_31619095 | 0.83 | 1.7e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of KLF13
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.2 | GO:0006527 | arginine catabolic process(GO:0006527) |
| 0.3 | 1.2 | GO:0006050 | mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051) |
| 0.1 | 1.0 | GO:0010968 | regulation of microtubule nucleation(GO:0010968) |
| 0.0 | 1.0 | GO:0007220 | Notch receptor processing(GO:0007220) |
| 0.3 | 0.8 | GO:0071423 | thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356) |
| 0.1 | 0.8 | GO:0010820 | positive regulation of T cell chemotaxis(GO:0010820) |
| 0.2 | 0.7 | GO:0043095 | regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105) |
| 0.1 | 0.7 | GO:0006287 | base-excision repair, gap-filling(GO:0006287) |
| 0.0 | 0.7 | GO:0009303 | rRNA transcription(GO:0009303) |
| 0.2 | 0.6 | GO:0070377 | regulation of ERK5 cascade(GO:0070376) negative regulation of ERK5 cascade(GO:0070377) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.0 | GO:0070765 | gamma-secretase complex(GO:0070765) |
| 0.1 | 0.7 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
| 0.1 | 0.6 | GO:0000214 | tRNA-intron endonuclease complex(GO:0000214) |
| 0.0 | 0.4 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
| 0.0 | 0.4 | GO:0035102 | PRC1 complex(GO:0035102) |
| 0.1 | 0.3 | GO:0044393 | microspike(GO:0044393) |
| 0.0 | 0.3 | GO:0000347 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
| 0.0 | 0.3 | GO:0030061 | mitochondrial crista(GO:0030061) |
| 0.0 | 0.3 | GO:0044232 | organelle membrane contact site(GO:0044232) |
| 0.1 | 0.2 | GO:0097543 | ciliary inversin compartment(GO:0097543) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 2.2 | GO:0016403 | dimethylargininase activity(GO:0016403) |
| 0.3 | 1.2 | GO:0045127 | N-acetylglucosamine kinase activity(GO:0045127) |
| 0.1 | 0.9 | GO:0030976 | thiamine pyrophosphate binding(GO:0030976) |
| 0.3 | 0.8 | GO:0015117 | thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) |
| 0.2 | 0.7 | GO:0044549 | GTP cyclohydrolase binding(GO:0044549) |
| 0.0 | 0.7 | GO:0008296 | 3'-5'-exodeoxyribonuclease activity(GO:0008296) |
| 0.1 | 0.6 | GO:0000213 | tRNA-intron endonuclease activity(GO:0000213) |
| 0.0 | 0.5 | GO:0022820 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.0 | 0.4 | GO:0003827 | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827) |
| 0.0 | 0.4 | GO:0097027 | ubiquitin-protein transferase activator activity(GO:0097027) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.0 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.0 | 0.8 | PID NECTIN PATHWAY | Nectin adhesion pathway |
| 0.0 | 0.6 | ST GA12 PATHWAY | G alpha 12 Pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.0 | REACTOME REGULATED PROTEOLYSIS OF P75NTR | Genes involved in Regulated proteolysis of p75NTR |
| 0.0 | 0.8 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.0 | 0.8 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.0 | 0.7 | REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND | Genes involved in Removal of the Flap Intermediate from the C-strand |
| 0.0 | 0.7 | REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
| 0.0 | 0.6 | REACTOME ERKS ARE INACTIVATED | Genes involved in ERKs are inactivated |
| 0.0 | 0.4 | REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE | Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle |
| 0.0 | 0.4 | REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA | Genes involved in G beta:gamma signalling through PLC beta |
| 0.0 | 0.2 | REACTOME CTNNB1 PHOSPHORYLATION CASCADE | Genes involved in Beta-catenin phosphorylation cascade |