ISMARA results: KLF12

Project

A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

Navigation

Downloads

Results for KLF12

Z-value: 2.13

Motif logo

Transcription factors associated with KLF12

Gene Symbol	Gene ID	Gene Info
KLF12 Ensembl NCBI GeneCards UniProt	ENSG00000118922.12	Kruppel like factor 12

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
KLF12	hg19_v2_chr13_-_74708372_74708409	-0.47	5.3e-01	Click!

Activity profile of KLF12 motif

Sorted Z-values of KLF12 motif

Top targets:

Search:

Show entries

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr9_-_34637806 Show fit	2.26	ENST00000477726.1	SIGMAR1 Ensembl NCBI GeneCards UniProt Show fit	sigma non-opioid intracellular receptor 1
chr1_+_24117627 Show fit	1.73	ENST00000400061.1	LYPLA2 Ensembl NCBI GeneCards UniProt Show fit	lysophospholipase II
chr22_-_39268192 Show fit	1.70	ENST00000216083.6	CBX6 Ensembl NCBI GeneCards UniProt Show fit	chromobox homolog 6
chr11_-_57089774 Show fit	1.58	ENST00000527207.1	TNKS1BP1 Ensembl NCBI GeneCards UniProt Show fit	tankyrase 1 binding protein 1, 182kDa
chr17_-_36831156 Show fit	1.46	ENST00000325814.5	C17orf96 Ensembl NCBI GeneCards UniProt Show fit	chromosome 17 open reading frame 96
chr11_+_22646739 Show fit	1.43	ENST00000428556.2	AC103801.2 Ensembl NCBI GeneCards UniProt Show fit	AC103801.2
chr9_+_131085095 Show fit	1.31	ENST00000372875.3	COQ4 Ensembl NCBI GeneCards UniProt Show fit	coenzyme Q4
chr22_-_39268308 Show fit	1.25	ENST00000407418.3	CBX6 Ensembl NCBI GeneCards UniProt Show fit	chromobox homolog 6
chr5_-_139930713 Show fit	1.22	ENST00000602657.1	SRA1 Ensembl NCBI GeneCards UniProt Show fit	steroid receptor RNA activator 1
chr10_-_71906342 Show fit	1.12	ENST00000287078.6 ENST00000335494.5	TYSND1 Ensembl NCBI GeneCards UniProt Show fit	trypsin domain containing 1

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF12

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	3.5	GO:0002084	protein depalmitoylation(GO:0002084)
0.1	2.9	GO:1901663	ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.3	2.6	GO:0038003	opioid receptor signaling pathway(GO:0038003)
0.1	2.6	GO:0010800	positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.4	2.5	GO:1902164	mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0	1.7	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742)
0.2	1.5	GO:0006452	translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.5	1.4	GO:0014859	negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.3	1.3	GO:0018262	isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.0	1.3	GO:0006266	DNA ligation(GO:0006266)

Showing 1 to 10 of 127 entries

Gene overrepresentation in cellular_component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	3.5	GO:0000792	heterochromatin(GO:0000792)
0.1	2.6	GO:0005640	nuclear outer membrane(GO:0005640)
0.1	2.4	GO:0030014	CCR4-NOT complex(GO:0030014)
0.0	2.2	GO:0045171	intercellular bridge(GO:0045171)
0.0	1.9	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.1	1.5	GO:0005642	annulate lamellae(GO:0005642)
0.0	1.4	GO:0035578	azurophil granule lumen(GO:0035578)
0.1	1.1	GO:0001673	male germ cell nucleus(GO:0001673)
0.1	0.9	GO:1990393	3M complex(GO:1990393)
0.1	0.8	GO:0001739	sex chromatin(GO:0001739)

Showing 1 to 10 of 44 entries

Gene overrepresentation in molecular_function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	3.5	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.3	2.6	GO:0004985	opioid receptor activity(GO:0004985)
0.2	2.4	GO:0071532	ankyrin repeat binding(GO:0071532)
0.0	2.3	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1	1.8	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.0	1.7	GO:0002039	p53 binding(GO:0002039)
0.1	1.5	GO:0017070	U6 snRNA binding(GO:0017070)
0.0	1.4	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0	1.4	GO:0003727	single-stranded RNA binding(GO:0003727)
0.1	1.3	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)

Showing 1 to 10 of 79 entries

Gene overrepresentation in C2:CP category:

Search:

Show entries

Total log-likelihood	Term	Description
2.6	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
2.1	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
1.7	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
1.2	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
1.2	PID REELIN PATHWAY	Reelin signaling pathway
1.1	PID ATM PATHWAY	ATM pathway
1.0	PID WNT SIGNALING PATHWAY	Wnt signaling network
1.0	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.8	PID EPHB FWD PATHWAY	EPHB forward signaling
0.5	ST GA12 PATHWAY	G alpha 12 Pathway

Showing 1 to 10 of 14 entries

Gene overrepresentation in C2:CP:REACTOME category:

Search:

Show entries

Total log-likelihood	Term	Description
2.2	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
1.9	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
1.5	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
1.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
1.1	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
1.1	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.8	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.8	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.7	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.7	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism

Showing 1 to 10 of 23 entries

Results for KLF12

Z-value: 2.13

Motif logo

Transcription factors associated with KLF12

Activity-expression correlation:

Activity profile of KLF12 motif

Sorted Z-values of KLF12 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF12

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: