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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for IRX5

Z-value: 0.40

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Transcription factors associated with IRX5

Gene Symbol Gene ID Gene Info
ENSG00000176842.10 iroquois homeobox 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRX5hg19_v2_chr16_+_54964740_549647890.742.6e-01Click!

Activity profile of IRX5 motif

Sorted Z-values of IRX5 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_149859466 0.22 ENST00000331128.3
histone cluster 2, H2ab
chr7_+_23210760 0.13 ENST00000366347.4
Uncharacterized protein
chr8_+_84824920 0.12 ENST00000523678.1
RP11-120I21.2
chr3_+_186158169 0.10 ENST00000435548.1
ENST00000421006.1
RP11-78H24.1
chr4_+_189376725 0.10 ENST00000510832.1
ENST00000510005.1
ENST00000503458.1
long intergenic non-protein coding RNA 1060
chr2_+_58655461 0.09 ENST00000429095.1
ENST00000429664.1
ENST00000452840.1
long intergenic non-protein coding RNA 1122
chr12_+_56114151 0.09 ENST00000547072.1
ENST00000552930.1
ENST00000257895.5
retinol dehydrogenase 5 (11-cis/9-cis)
chr13_-_46716969 0.09 ENST00000435666.2
lymphocyte cytosolic protein 1 (L-plastin)
chr9_+_95909309 0.08 ENST00000366188.2
RP11-370F5.4
chr11_-_1619524 0.08 ENST00000412090.1
keratin associated protein 5-2
chr6_+_12008986 0.08 ENST00000491710.1
human immunodeficiency virus type I enhancer binding protein 1
chr8_+_101349823 0.07 ENST00000519566.1
KB-1991G8.1
chr15_+_41057818 0.06 ENST00000558467.1
GTP cyclohydrolase I feedback regulator
chr1_+_81106951 0.06 ENST00000443565.1
RP5-887A10.1
chr5_+_140566 0.06 ENST00000502646.1
pleckstrin homology domain containing, family G (with RhoGef domain) member 4B
chr13_-_34250861 0.06 ENST00000445227.1
ENST00000454681.2
RP11-141M1.3
chr4_+_144312659 0.06 ENST00000509992.1
GRB2-associated binding protein 1
chr18_-_69246167 0.06 ENST00000566582.1
RP11-510D19.1
chr12_+_56114189 0.05 ENST00000548082.1
retinol dehydrogenase 5 (11-cis/9-cis)
chrX_-_52258669 0.05 ENST00000441417.1
X antigen family, member 1A
chrX_+_52513455 0.05 ENST00000446098.1
X antigen family, member 1C
chr6_+_26204825 0.05 ENST00000360441.4
histone cluster 1, H4e
chr12_+_32655110 0.05 ENST00000546442.1
ENST00000583694.1
FYVE, RhoGEF and PH domain containing 4
chr1_-_152086556 0.05 ENST00000368804.1
trichohyalin
chr12_-_11036844 0.05 ENST00000428168.2
proline-rich protein HaeIII subfamily 1
chr8_+_9009202 0.04 ENST00000518496.1
Uncharacterized protein
chr3_+_52245458 0.04 ENST00000459884.1
aminolevulinate, delta-, synthase 1
chrX_+_153238220 0.04 ENST00000425274.1
transmembrane protein 187
chr4_+_123653882 0.04 ENST00000433287.1
Bardet-Biedl syndrome 12
chr5_-_13944652 0.04 ENST00000265104.4
dynein, axonemal, heavy chain 5
chrX_+_99899180 0.04 ENST00000373004.3
sushi-repeat containing protein, X-linked 2
chr12_+_21679220 0.04 ENST00000256969.2
chromosome 12 open reading frame 39
chr4_-_22444733 0.04 ENST00000508133.1
G protein-coupled receptor 125
chr4_+_141264597 0.04 ENST00000338517.4
ENST00000394203.3
ENST00000506322.1
short coiled-coil protein
chr12_+_2912363 0.04 ENST00000544366.1
FK506 binding protein 4, 59kDa
chr17_+_12859080 0.04 ENST00000583608.1
Rho GTPase activating protein 44
chr20_+_10199468 0.04 ENST00000254976.2
ENST00000304886.2
synaptosomal-associated protein, 25kDa
chr2_-_127963343 0.04 ENST00000335247.7
cytochrome P450, family 27, subfamily C, polypeptide 1
chr11_+_110225855 0.04 ENST00000526605.1
ENST00000526703.1
RP11-347E10.1
chr13_+_24844857 0.03 ENST00000409126.1
ENST00000343003.6
spermatogenesis associated 13
chr19_-_36909528 0.03 ENST00000392161.3
ENST00000392171.1
ZFP82 zinc finger protein
chr11_-_31014214 0.03 ENST00000406071.2
ENST00000339794.5
doublecortin domain containing 1
chrX_+_52240504 0.03 ENST00000399805.2
X antigen family, member 1B
chr19_-_52227221 0.03 ENST00000222115.1
ENST00000540069.2
hyaluronan synthase 1
chr22_+_20877924 0.03 ENST00000445189.1
mediator complex subunit 15
chr2_+_173686303 0.03 ENST00000397087.3
Rap guanine nucleotide exchange factor (GEF) 4
chr18_-_69246186 0.03 ENST00000568095.1
RP11-510D19.1
chr11_-_60010556 0.03 ENST00000427611.2
membrane-spanning 4-domains, subfamily A, member 4E
chr2_+_38177620 0.03 ENST00000402091.3
regulator of microtubule dynamics 2
chr10_-_14050522 0.03 ENST00000342409.2
FERM domain containing 4A
chr1_+_10509971 0.03 ENST00000320498.4
cortistatin
chr12_-_10282836 0.03 ENST00000304084.8
ENST00000353231.5
ENST00000525605.1
C-type lectin domain family 7, member A
chr7_-_111424506 0.03 ENST00000450156.1
ENST00000494651.2
dedicator of cytokinesis 4
chr11_+_61891445 0.03 ENST00000394818.3
ENST00000533896.1
ENST00000278849.4
inner centromere protein antigens 135/155kDa
chr2_+_38177575 0.03 ENST00000407257.1
ENST00000417700.2
ENST00000234195.3
ENST00000442857.1
regulator of microtubule dynamics 2
chr4_+_169842707 0.03 ENST00000503290.1
palladin, cytoskeletal associated protein
chr18_+_33709834 0.03 ENST00000358232.6
ENST00000351393.6
ENST00000442325.2
ENST00000423854.2
ENST00000350494.6
ENST00000542824.1
elongator acetyltransferase complex subunit 2
chr15_-_81616446 0.03 ENST00000302824.6
StAR-related lipid transfer (START) domain containing 5
chr7_+_13141010 0.03 ENST00000443947.1
AC011288.2
chr2_-_231989808 0.03 ENST00000258400.3
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr8_+_120885949 0.03 ENST00000523492.1
ENST00000286234.5
DEP domain containing MTOR-interacting protein
chr12_+_76653682 0.03 ENST00000553247.1
RP11-54A9.1
chr21_+_38792602 0.03 ENST00000398960.2
ENST00000398956.2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
chr13_-_20110902 0.03 ENST00000390680.2
ENST00000382977.4
ENST00000382975.4
ENST00000457266.2
transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
chr3_-_127541194 0.02 ENST00000453507.2
monoglyceride lipase
chr3_+_12392971 0.02 ENST00000287820.6
peroxisome proliferator-activated receptor gamma
chr6_+_27925019 0.02 ENST00000244623.1
olfactory receptor, family 2, subfamily B, member 6
chr9_-_3489428 0.02 ENST00000451859.1
regulatory factor X, 3 (influences HLA class II expression)
chr4_+_113739244 0.02 ENST00000503271.1
ENST00000503423.1
ENST00000506722.1
ankyrin 2, neuronal
chr7_-_111424462 0.02 ENST00000437129.1
dedicator of cytokinesis 4
chr15_+_65204075 0.02 ENST00000380230.3
ENST00000357698.3
ENST00000395720.1
ENST00000496660.1
ENST00000319580.8
ankyrin repeat and death domain containing 1A
chr9_+_42704004 0.02 ENST00000457288.1
COBW domain containing 7
chr8_+_125463048 0.02 ENST00000328599.3
tRNA methyltransferase 12 homolog (S. cerevisiae)
chr12_+_53848549 0.02 ENST00000439930.3
ENST00000548933.1
ENST00000562264.1
poly(rC) binding protein 2
chr2_+_228735763 0.02 ENST00000373666.2
dynein assembly factor with WDR repeat domains 1
chr1_+_53308398 0.02 ENST00000371528.1
zyg-11 family member A, cell cycle regulator
chr7_+_871559 0.02 ENST00000421580.1
Sad1 and UNC84 domain containing 1
chr1_-_89488510 0.02 ENST00000564665.1
ENST00000370481.4
guanylate binding protein 3
chr4_+_56212270 0.02 ENST00000264228.4
steroid 5 alpha-reductase 3
chr15_+_66585555 0.02 ENST00000319194.5
ENST00000525134.2
ENST00000441424.2
DIS3 mitotic control homolog (S. cerevisiae)-like
chr19_-_44388116 0.02 ENST00000587539.1
zinc finger protein 404
chr8_-_108510224 0.02 ENST00000517746.1
ENST00000297450.3
angiopoietin 1
chr15_+_25200108 0.02 ENST00000577949.1
ENST00000338094.6
ENST00000338327.4
ENST00000579070.1
ENST00000577565.1
SNRPN upstream reading frame protein
small nuclear ribonucleoprotein polypeptide N
chr6_+_106988986 0.02 ENST00000457437.1
ENST00000535438.1
absent in melanoma 1
chr1_-_85870177 0.02 ENST00000542148.1
dimethylarginine dimethylaminohydrolase 1
chr13_+_24844819 0.02 ENST00000399949.2
spermatogenesis associated 13
chr16_+_19467772 0.02 ENST00000219821.5
ENST00000561503.1
ENST00000564959.1
transmembrane channel-like 5
chr1_-_115124257 0.02 ENST00000369541.3
breast carcinoma amplified sequence 2
chr17_-_42327236 0.02 ENST00000399246.2
AC003102.1
chr11_+_31531291 0.02 ENST00000350638.5
ENST00000379163.5
ENST00000395934.2
elongator acetyltransferase complex subunit 4
chrX_+_15767971 0.02 ENST00000479740.1
ENST00000454127.2
carbonic anhydrase VB, mitochondrial
chr19_-_44952635 0.02 ENST00000592308.1
ENST00000588931.1
ENST00000291187.4
zinc finger protein 229
chr1_-_21377383 0.02 ENST00000374935.3
eukaryotic translation initiation factor 4 gamma, 3
chr10_+_95326416 0.02 ENST00000371481.4
ENST00000371483.4
ENST00000604414.1
free fatty acid receptor 4
chr22_+_18721427 0.02 ENST00000342888.3
Uncharacterized protein
chr8_-_67976509 0.02 ENST00000518747.1
COP9 signalosome subunit 5
chr2_+_102624977 0.02 ENST00000441002.1
interleukin 1 receptor, type II
chr18_+_22006580 0.02 ENST00000284202.4
impact RWD domain protein
chr4_+_26344754 0.02 ENST00000515573.1
recombination signal binding protein for immunoglobulin kappa J region
chr3_+_158787041 0.02 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1 readthrough
chr12_+_76653611 0.02 ENST00000550380.1
RP11-54A9.1
chr8_+_27947746 0.02 ENST00000521015.1
ENST00000521570.1
elongator acetyltransferase complex subunit 3
chr17_-_18430160 0.02 ENST00000392176.3
family with sequence similarity 106, member A
chr3_+_35681728 0.01 ENST00000421492.1
ENST00000458225.1
ENST00000337271.5
cAMP-regulated phosphoprotein, 21kDa
chr7_-_41742697 0.01 ENST00000242208.4
inhibin, beta A
chr3_+_111758553 0.01 ENST00000419127.1
transmembrane protease, serine 7
chr3_-_124606502 0.01 ENST00000483168.1
integrin, beta 5
chr12_+_58335360 0.01 ENST00000300145.3
XRCC6 binding protein 1
chr13_-_20080080 0.01 ENST00000400103.2
transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
chr17_+_75447326 0.01 ENST00000591088.1
septin 9
chr17_+_58018269 0.01 ENST00000591035.1
Uncharacterized protein
chr1_+_113010056 0.01 ENST00000369686.5
wingless-type MMTV integration site family, member 2B
chr14_-_95624227 0.01 ENST00000526495.1
dicer 1, ribonuclease type III
chrX_-_135962923 0.01 ENST00000565438.1
RNA binding motif protein, X-linked
chr3_+_138066539 0.01 ENST00000289104.4
muscle RAS oncogene homolog
chr12_+_106751436 0.01 ENST00000228347.4
polymerase (RNA) III (DNA directed) polypeptide B
chr15_+_25200074 0.01 ENST00000390687.4
ENST00000584968.1
ENST00000346403.6
ENST00000554227.2
small nuclear ribonucleoprotein polypeptide N
chr1_-_201438282 0.01 ENST00000367311.3
ENST00000367309.1
pleckstrin homology-like domain, family A, member 3
chr20_+_43990576 0.01 ENST00000372727.1
ENST00000414310.1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr16_-_58585513 0.01 ENST00000245138.4
ENST00000567285.1
CCR4-NOT transcription complex, subunit 1
chr8_-_101724989 0.01 ENST00000517403.1
poly(A) binding protein, cytoplasmic 1
chr1_+_63989004 0.01 ENST00000371088.4
EF-hand calcium binding domain 7
chr3_-_3221358 0.01 ENST00000424814.1
ENST00000450014.1
ENST00000231948.4
ENST00000432408.2
cereblon
chr11_+_114310237 0.01 ENST00000539119.1
RNA exonuclease 2
chr9_-_4666421 0.01 ENST00000381895.5
spermatogenesis associated 6-like
chr7_-_87856280 0.01 ENST00000490437.1
ENST00000431660.1
sorcin
chr12_-_120315074 0.01 ENST00000261833.7
ENST00000392521.2
citron (rho-interacting, serine/threonine kinase 21)
chr14_+_96722539 0.01 ENST00000553356.1
bradykinin receptor B1
chr1_+_155579979 0.01 ENST00000452804.2
ENST00000538143.1
ENST00000245564.2
ENST00000368341.4
misato 1, mitochondrial distribution and morphology regulator
chr7_-_87856303 0.01 ENST00000394641.3
sorcin
chr15_-_44116873 0.01 ENST00000267812.3
microfibrillar-associated protein 1
chr1_+_22778337 0.01 ENST00000404138.1
ENST00000400239.2
ENST00000375647.4
ENST00000374651.4
zinc finger and BTB domain containing 40
chr7_+_133615169 0.01 ENST00000541309.1
exocyst complex component 4
chr8_+_22225041 0.01 ENST00000289952.5
ENST00000524285.1
solute carrier family 39 (zinc transporter), member 14
chrX_-_15333736 0.01 ENST00000380470.3
ankyrin repeat and SOCS box containing 11
chr19_+_50691437 0.01 ENST00000598205.1
myosin, heavy chain 14, non-muscle
chr14_-_74769759 0.01 ENST00000356924.4
ATP-binding cassette, sub-family D (ALD), member 4
chr17_+_41561317 0.01 ENST00000540306.1
ENST00000262415.3
ENST00000605777.1
DEAH (Asp-Glu-Ala-His) box polypeptide 8
chr8_+_95558771 0.01 ENST00000391679.1
HCG2009141; PRO2397; Uncharacterized protein
chr6_-_117747015 0.01 ENST00000368508.3
ENST00000368507.3
c-ros oncogene 1 , receptor tyrosine kinase
chr4_+_41361616 0.01 ENST00000513024.1
LIM and calponin homology domains 1
chr17_-_6524159 0.01 ENST00000589033.1
KIAA0753
chr8_+_27631903 0.01 ENST00000305188.8
establishment of sister chromatid cohesion N-acetyltransferase 2
chr3_+_155838337 0.01 ENST00000490337.1
ENST00000389636.5
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr12_-_25102252 0.01 ENST00000261192.7
branched chain amino-acid transaminase 1, cytosolic
chr3_+_160473996 0.01 ENST00000498165.1
protein phosphatase, Mg2+/Mn2+ dependent, 1L
chr17_+_22022437 0.01 ENST00000540040.1
MT-RNR2-like 1
chr13_+_96085847 0.01 ENST00000376873.3
claudin 10
chr3_-_50378235 0.01 ENST00000357043.2
Ras association (RalGDS/AF-6) domain family member 1
chr19_-_38743878 0.01 ENST00000587515.1
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr9_-_125667618 0.01 ENST00000423239.2
ring finger and CCCH-type domains 2
chr12_-_58329888 0.01 ENST00000546580.1
RP11-620J15.3
chr5_+_67576109 0.01 ENST00000522084.1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr10_+_96698406 0.01 ENST00000260682.6
cytochrome P450, family 2, subfamily C, polypeptide 9
chr19_-_2740036 0.01 ENST00000586572.1
ENST00000269740.4
Uncharacterized protein
solute carrier family 39 (zinc transporter), member 3
chr1_+_196743943 0.01 ENST00000471440.2
ENST00000391985.3
complement factor H-related 3
chr3_-_12883026 0.01 ENST00000396953.2
ENST00000457131.1
ENST00000435983.1
ENST00000273223.6
ENST00000396957.1
ENST00000429711.2
ribosomal protein L32
chr7_+_66386204 0.01 ENST00000341567.4
ENST00000607045.1
transmembrane protein 248
chr8_-_17555164 0.01 ENST00000297488.6
microtubule associated tumor suppressor 1
chr13_+_97928395 0.01 ENST00000445661.2
muscleblind-like splicing regulator 2
chr9_+_71819927 0.01 ENST00000535702.1
tight junction protein 2
chr18_-_28622774 0.01 ENST00000434452.1
desmocollin 3
chr3_-_27498235 0.01 ENST00000295736.5
ENST00000428386.1
ENST00000428179.1
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr1_+_145525015 0.01 ENST00000539363.1
ENST00000538811.1
integrin, alpha 10
chrX_-_19988382 0.01 ENST00000356980.3
ENST00000379687.3
ENST00000379682.4
chromosome X open reading frame 23
chr2_+_210517895 0.01 ENST00000447185.1
microtubule-associated protein 2
chr2_-_38056538 0.01 ENST00000413792.1
long intergenic non-protein coding RNA 211
chr11_+_22688150 0.01 ENST00000454584.2
growth arrest-specific 2
chr4_+_70146217 0.01 ENST00000335568.5
ENST00000511240.1
UDP glucuronosyltransferase 2 family, polypeptide B28
chr5_+_54455946 0.01 ENST00000503787.1
ENST00000296734.6
ENST00000515370.1
glutathione peroxidase 8 (putative)
chr20_-_3762087 0.01 ENST00000379756.3
sperm flagellar 1
chr16_+_87636474 0.01 ENST00000284262.2
junctophilin 3
chr18_+_616672 0.00 ENST00000338387.7
clusterin-like 1 (retinal)
chr1_+_196743912 0.00 ENST00000367425.4
complement factor H-related 3
chr1_+_202317815 0.00 ENST00000608999.1
ENST00000336894.4
ENST00000480184.1
protein phosphatase 1, regulatory subunit 12B
chrX_+_12809463 0.00 ENST00000380663.3
ENST00000380668.5
ENST00000398491.2
ENST00000489404.1
phosphoribosyl pyrophosphate synthetase 2
chr1_-_21377447 0.00 ENST00000374937.3
ENST00000264211.8
eukaryotic translation initiation factor 4 gamma, 3
chr3_-_72897545 0.00 ENST00000325599.8
SHQ1, H/ACA ribonucleoprotein assembly factor
chr2_-_206950996 0.00 ENST00000414320.1
INO80 complex subunit D
chr5_+_169011033 0.00 ENST00000513795.1
spindle apparatus coiled-coil protein 1
chr11_+_34999328 0.00 ENST00000526309.1
pyruvate dehydrogenase complex, component X
chr19_-_40596828 0.00 ENST00000414720.2
ENST00000455521.1
ENST00000340963.5
ENST00000595773.1
zinc finger protein 780A
chr5_-_177207634 0.00 ENST00000513554.1
ENST00000440605.3
family with sequence similarity 153, member A
chr12_-_123728548 0.00 ENST00000545406.1
M-phase phosphoprotein 9
chr16_-_90128733 0.00 ENST00000325921.6
PR domain containing 7
chr5_+_169010638 0.00 ENST00000265295.4
ENST00000506574.1
ENST00000515224.1
ENST00000508247.1
ENST00000513941.1
spindle apparatus coiled-coil protein 1
chr10_-_51958906 0.00 ENST00000489640.1
N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
chr6_-_154677900 0.00 ENST00000265198.4
ENST00000520261.1
interaction protein for cytohesin exchange factors 1
chr3_+_111630451 0.00 ENST00000495180.1
pleckstrin homology-like domain, family B, member 2
chr17_-_29641084 0.00 ENST00000544462.1
ecotropic viral integration site 2B
chr9_-_37465396 0.00 ENST00000307750.4
zinc finger and BTB domain containing 5
chr2_+_201173667 0.00 ENST00000409755.3
spermatogenesis associated, serine-rich 2-like
chr18_+_52258390 0.00 ENST00000321600.1
dynactin associated protein
chr7_+_13141097 0.00 ENST00000411542.1
AC011288.2
chr18_-_32924372 0.00 ENST00000261332.6
ENST00000399061.3
zinc finger protein 24
chrX_+_108779004 0.00 ENST00000218004.1
nuclear transport factor 2-like export factor 2
chr1_-_244006528 0.00 ENST00000336199.5
ENST00000263826.5
v-akt murine thymoma viral oncogene homolog 3
chr1_+_97188188 0.00 ENST00000541987.1
polypyrimidine tract binding protein 2
chr3_-_168865522 0.00 ENST00000464456.1
MDS1 and EVI1 complex locus
chr7_-_55583740 0.00 ENST00000453256.1
vesicular, overexpressed in cancer, prosurvival protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of IRX5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0043095 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.0 0.0 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.0 GO:0005502 11-cis retinal binding(GO:0005502) all-trans retinal binding(GO:0005503)