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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)
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Results for IRX3
Z-value: 1.72
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Transcription factors associated with IRX3
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| IRX3 | hg19_v2_chr16_-_54320675_54320715 | -0.58 | 4.2e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of IRX3
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.9 | GO:0007079 | mitotic chromosome movement towards spindle pole(GO:0007079) |
| 0.1 | 0.9 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
| 0.0 | 0.9 | GO:0032201 | telomere maintenance via semi-conservative replication(GO:0032201) |
| 0.0 | 0.8 | GO:0034501 | protein localization to kinetochore(GO:0034501) |
| 0.0 | 0.8 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
| 0.1 | 0.7 | GO:0097500 | receptor localization to nonmotile primary cilium(GO:0097500) |
| 0.1 | 0.7 | GO:0033314 | mitotic DNA replication checkpoint(GO:0033314) |
| 0.0 | 0.7 | GO:1900364 | negative regulation of mRNA polyadenylation(GO:1900364) |
| 0.1 | 0.6 | GO:1990926 | short-term synaptic potentiation(GO:1990926) |
| 0.1 | 0.6 | GO:1900625 | regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.6 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 0.0 | 1.4 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.1 | 1.1 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
| 0.1 | 0.8 | GO:0070032 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) |
| 0.1 | 0.8 | GO:0034464 | BBSome(GO:0034464) |
| 0.1 | 0.6 | GO:0034680 | integrin alpha10-beta1 complex(GO:0034680) |
| 0.1 | 0.6 | GO:0035692 | macrophage migration inhibitory factor receptor complex(GO:0035692) |
| 0.0 | 0.6 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
| 0.0 | 0.6 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 0.0 | 0.6 | GO:0031105 | septin complex(GO:0031105) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.7 | GO:0043515 | kinetochore binding(GO:0043515) |
| 0.0 | 1.6 | GO:0070717 | poly-purine tract binding(GO:0070717) |
| 0.0 | 1.3 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.0 | 1.3 | GO:0004532 | exoribonuclease activity(GO:0004532) |
| 0.0 | 1.2 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
| 0.1 | 1.1 | GO:0035251 | UDP-glucosyltransferase activity(GO:0035251) |
| 0.0 | 0.9 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.0 | 0.9 | GO:0070840 | dynein complex binding(GO:0070840) |
| 0.2 | 0.7 | GO:0019781 | NEDD8 activating enzyme activity(GO:0019781) |
| 0.1 | 0.7 | GO:0008607 | phosphorylase kinase regulator activity(GO:0008607) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.1 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.0 | 0.5 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.0 | 0.5 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.0 | 0.4 | PID FOXO PATHWAY | FoxO family signaling |
| 0.0 | 0.2 | ST JAK STAT PATHWAY | Jak-STAT Pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.3 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.1 | 1.0 | REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
| 0.0 | 0.9 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.0 | 0.9 | REACTOME RNA POL I TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase I Transcription Termination |
| 0.0 | 0.8 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.0 | 0.7 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.0 | 0.5 | REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE | Genes involved in mRNA Decay by 3' to 5' Exoribonuclease |
| 0.0 | 0.5 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.0 | 0.5 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.0 | 0.5 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |