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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for IRX2

Z-value: 0.24

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Transcription factors associated with IRX2

Gene Symbol Gene ID Gene Info
IRX2
ENSG00000170561.8 iroquois homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRX2hg19_v2_chr5_-_2751762_27517840.811.9e-01Click!

Activity profile of IRX2 motif

Sorted Z-values of IRX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_41322332 0.15 ENST00000590740.1
RP11-242D8.1
RP11-242D8.1
chr17_+_76037081 0.11 ENST00000588549.1
TNRC6C
trinucleotide repeat containing 6C
chrX_-_70331298 0.11 ENST00000456850.2
ENST00000473378.1
ENST00000487883.1
ENST00000374202.2
IL2RG
interleukin 2 receptor, gamma
chr7_+_93652116 0.11 ENST00000415536.1
AC003092.1
AC003092.1
chr14_+_52327350 0.10 ENST00000555472.1
ENST00000556766.1
GNG2
guanine nucleotide binding protein (G protein), gamma 2
chr8_+_40018977 0.09 ENST00000520487.1
RP11-470M17.2
RP11-470M17.2
chr6_-_27841289 0.07 ENST00000355981.2
HIST1H4L
histone cluster 1, H4l
chr5_-_150138246 0.07 ENST00000518015.1
DCTN4
dynactin 4 (p62)
chr1_-_54405773 0.07 ENST00000371376.1
HSPB11
heat shock protein family B (small), member 11
chr14_-_50999190 0.07 ENST00000557390.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr18_-_33702078 0.07 ENST00000586829.1
SLC39A6
solute carrier family 39 (zinc transporter), member 6
chr9_-_139981121 0.07 ENST00000596585.1
AL807752.1
Uncharacterized protein
chr8_+_67104323 0.07 ENST00000518412.1
ENST00000518035.1
ENST00000517725.1
LINC00967
long intergenic non-protein coding RNA 967
chr7_-_130597935 0.07 ENST00000447307.1
ENST00000418546.1
MIR29B1
microRNA 29a
chr4_+_57371509 0.06 ENST00000360096.2
ARL9
ADP-ribosylation factor-like 9
chr11_+_77532233 0.06 ENST00000525409.1
AAMDC
adipogenesis associated, Mth938 domain containing
chr20_+_2083540 0.06 ENST00000400064.3
STK35
serine/threonine kinase 35
chr1_-_238649319 0.06 ENST00000400946.2
RP11-371I1.2
long intergenic non-protein coding RNA 1139
chr22_-_36013368 0.06 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
MB
myoglobin
chrX_+_155227371 0.05 ENST00000369423.2
ENST00000540897.1
IL9R
interleukin 9 receptor
chr6_+_27925019 0.05 ENST00000244623.1
OR2B6
olfactory receptor, family 2, subfamily B, member 6
chrX_+_155227246 0.05 ENST00000244174.5
ENST00000424344.3
IL9R
interleukin 9 receptor
chr16_+_81272287 0.05 ENST00000425577.2
ENST00000564552.1
BCMO1
beta-carotene 15,15'-monooxygenase 1
chr9_+_35792151 0.04 ENST00000342694.2
NPR2
natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
chr13_-_22033392 0.04 ENST00000320220.9
ENST00000415724.1
ENST00000422251.1
ENST00000382466.3
ENST00000542645.1
ENST00000400590.3
ZDHHC20
zinc finger, DHHC-type containing 20
chr12_+_32655110 0.04 ENST00000546442.1
ENST00000583694.1
FGD4
FYVE, RhoGEF and PH domain containing 4
chr3_+_184534994 0.04 ENST00000441141.1
ENST00000445089.1
VPS8
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr14_+_23790655 0.04 ENST00000397276.2
PABPN1
poly(A) binding protein, nuclear 1
chr2_+_159651821 0.04 ENST00000309950.3
ENST00000409042.1
DAPL1
death associated protein-like 1
chr11_+_102552041 0.04 ENST00000537079.1
RP11-817J15.3
Uncharacterized protein
chr14_-_75536182 0.04 ENST00000555463.1
ACYP1
acylphosphatase 1, erythrocyte (common) type
chr8_+_81397846 0.04 ENST00000379091.4
ZBTB10
zinc finger and BTB domain containing 10
chr9_-_35812236 0.03 ENST00000340291.2
SPAG8
sperm associated antigen 8
chr3_+_122044084 0.03 ENST00000264474.3
ENST00000479204.1
CSTA
cystatin A (stefin A)
chr9_+_130159593 0.03 ENST00000419132.1
SLC2A8
solute carrier family 2 (facilitated glucose transporter), member 8
chr1_-_151148442 0.03 ENST00000441701.1
ENST00000416280.2
TMOD4
tropomodulin 4 (muscle)
chr1_-_207095324 0.03 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
FAIM3
Fas apoptotic inhibitory molecule 3
chr5_-_94417186 0.03 ENST00000312216.8
ENST00000512425.1
MCTP1
multiple C2 domains, transmembrane 1
chr21_-_22175341 0.03 ENST00000416768.1
ENST00000452561.1
ENST00000419299.1
ENST00000437238.1
LINC00320
long intergenic non-protein coding RNA 320
chr12_+_65996599 0.03 ENST00000539116.1
ENST00000541391.1
RP11-221N13.3
RP11-221N13.3
chr2_-_42180940 0.03 ENST00000378711.2
C2orf91
chromosome 2 open reading frame 91
chr1_-_8939265 0.03 ENST00000489867.1
ENO1
enolase 1, (alpha)
chr4_+_83821835 0.03 ENST00000302236.5
THAP9
THAP domain containing 9
chr4_-_83821676 0.03 ENST00000355196.2
ENST00000507676.1
ENST00000506495.1
ENST00000507051.1
SEC31A
SEC31 homolog A (S. cerevisiae)
chr7_-_107770794 0.03 ENST00000205386.4
ENST00000418464.1
ENST00000388781.3
ENST00000388780.3
ENST00000414450.2
LAMB4
laminin, beta 4
chr1_+_215747118 0.03 ENST00000448333.1
KCTD3
potassium channel tetramerization domain containing 3
chr11_+_62648357 0.03 ENST00000541372.1
ENST00000539458.1
SLC3A2
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr4_-_120243545 0.03 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chr4_+_26165074 0.03 ENST00000512351.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chrX_-_100129320 0.03 ENST00000372966.3
NOX1
NADPH oxidase 1
chr5_-_94417314 0.03 ENST00000505208.1
MCTP1
multiple C2 domains, transmembrane 1
chr8_+_94767072 0.03 ENST00000452276.1
ENST00000453321.3
ENST00000498673.1
ENST00000518319.1
TMEM67
transmembrane protein 67
chr4_-_22444733 0.03 ENST00000508133.1
GPR125
G protein-coupled receptor 125
chr10_+_46997926 0.03 ENST00000374314.4
GPRIN2
G protein regulated inducer of neurite outgrowth 2
chr12_-_10007448 0.02 ENST00000538152.1
CLEC2B
C-type lectin domain family 2, member B
chr7_-_105332084 0.02 ENST00000472195.1
ATXN7L1
ataxin 7-like 1
chr22_+_29168652 0.02 ENST00000249064.4
ENST00000444523.1
ENST00000448492.2
ENST00000421503.2
CCDC117
coiled-coil domain containing 117
chr14_+_101295638 0.02 ENST00000523671.2
MEG3
maternally expressed 3 (non-protein coding)
chr4_+_119606523 0.02 ENST00000388822.5
ENST00000506780.1
ENST00000508801.1
METTL14
methyltransferase like 14
chr12_+_66218903 0.02 ENST00000393577.3
HMGA2
high mobility group AT-hook 2
chr3_-_15140629 0.02 ENST00000507357.1
ENST00000449050.1
ENST00000253699.3
ENST00000435849.3
ENST00000476527.2
ZFYVE20
zinc finger, FYVE domain containing 20
chr4_+_159131630 0.02 ENST00000504569.1
ENST00000509278.1
ENST00000514558.1
ENST00000503200.1
TMEM144
transmembrane protein 144
chr9_-_35812140 0.02 ENST00000497810.1
ENST00000396638.2
ENST00000484764.1
SPAG8
sperm associated antigen 8
chr12_-_112450915 0.02 ENST00000437003.2
ENST00000552374.2
ENST00000550831.3
ENST00000354825.3
ENST00000549537.2
ENST00000355445.3
TMEM116
transmembrane protein 116
chr6_-_136847099 0.02 ENST00000438100.2
MAP7
microtubule-associated protein 7
chr2_-_109605663 0.02 ENST00000409271.1
ENST00000258443.2
ENST00000376651.1
EDAR
ectodysplasin A receptor
chr16_+_57680043 0.02 ENST00000569154.1
GPR56
G protein-coupled receptor 56
chr19_+_13134772 0.02 ENST00000587760.1
ENST00000585575.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr10_-_14596140 0.02 ENST00000496330.1
FAM107B
family with sequence similarity 107, member B
chrX_+_19373700 0.02 ENST00000379804.1
PDHA1
pyruvate dehydrogenase (lipoamide) alpha 1
chr7_+_80275953 0.02 ENST00000538969.1
ENST00000544133.1
ENST00000433696.2
CD36
CD36 molecule (thrombospondin receptor)
chr19_-_40336969 0.02 ENST00000599134.1
ENST00000597634.1
ENST00000598417.1
ENST00000601274.1
ENST00000594309.1
ENST00000221801.3
FBL
fibrillarin
chr16_+_58537737 0.02 ENST00000561738.1
NDRG4
NDRG family member 4
chr19_+_18669809 0.02 ENST00000602094.1
KXD1
KxDL motif containing 1
chr2_-_70520539 0.02 ENST00000482975.2
ENST00000438261.1
SNRPG
small nuclear ribonucleoprotein polypeptide G
chr3_-_126327398 0.02 ENST00000383572.2
TXNRD3NB
thioredoxin reductase 3 neighbor
chr7_-_33140498 0.02 ENST00000448915.1
RP9
retinitis pigmentosa 9 (autosomal dominant)
chr6_-_160209471 0.02 ENST00000539948.1
TCP1
t-complex 1
chrX_-_119077695 0.02 ENST00000371410.3
NKAP
NFKB activating protein
chr7_-_21985489 0.02 ENST00000356195.5
ENST00000447180.1
ENST00000373934.4
ENST00000457951.1
CDCA7L
cell division cycle associated 7-like
chr8_-_90993869 0.01 ENST00000517772.1
NBN
nibrin
chr4_-_153332886 0.01 ENST00000603841.1
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr16_+_82068585 0.01 ENST00000563491.1
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr12_+_32655048 0.01 ENST00000427716.2
ENST00000266482.3
FGD4
FYVE, RhoGEF and PH domain containing 4
chr15_-_45670924 0.01 ENST00000396659.3
GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr5_-_142814241 0.01 ENST00000504572.1
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr14_+_75536280 0.01 ENST00000238686.8
ZC2HC1C
zinc finger, C2HC-type containing 1C
chr7_+_72395617 0.01 ENST00000434423.2
POM121
POM121 transmembrane nucleoporin
chr5_-_94417339 0.01 ENST00000429576.2
ENST00000508509.1
ENST00000510732.1
MCTP1
multiple C2 domains, transmembrane 1
chr3_+_14061155 0.01 ENST00000532924.1
TPRXL
tetra-peptide repeat homeobox-like
chr8_+_98900132 0.01 ENST00000520016.1
MATN2
matrilin 2
chr1_-_156698181 0.01 ENST00000313146.6
ISG20L2
interferon stimulated exonuclease gene 20kDa-like 2
chr6_-_136847610 0.01 ENST00000454590.1
ENST00000432797.2
MAP7
microtubule-associated protein 7
chr2_+_171640291 0.01 ENST00000409885.1
ERICH2
glutamate-rich 2
chr3_+_148457585 0.01 ENST00000402260.1
AGTR1
angiotensin II receptor, type 1
chr1_+_17516275 0.01 ENST00000412427.1
RP11-380J14.1
RP11-380J14.1
chr12_+_112856690 0.01 ENST00000392597.1
ENST00000351677.2
PTPN11
protein tyrosine phosphatase, non-receptor type 11
chr16_+_58426296 0.01 ENST00000426538.2
ENST00000328514.7
ENST00000318129.5
GINS3
GINS complex subunit 3 (Psf3 homolog)
chr10_+_102672712 0.01 ENST00000370271.3
ENST00000370269.3
ENST00000609386.1
FAM178A
family with sequence similarity 178, member A
chr7_+_95115210 0.01 ENST00000428113.1
ENST00000325885.5
ASB4
ankyrin repeat and SOCS box containing 4
chr17_+_7761013 0.01 ENST00000571846.1
CYB5D1
cytochrome b5 domain containing 1
chr14_+_50999744 0.01 ENST00000441560.2
ATL1
atlastin GTPase 1
chr19_-_55953704 0.01 ENST00000416792.1
SHISA7
shisa family member 7
chr10_-_14614311 0.01 ENST00000479731.1
ENST00000468492.1
FAM107B
family with sequence similarity 107, member B
chr17_-_2615031 0.01 ENST00000576885.1
ENST00000574426.2
CLUH
clustered mitochondria (cluA/CLU1) homolog
chr9_-_13175823 0.01 ENST00000545857.1
MPDZ
multiple PDZ domain protein
chr11_-_59383617 0.01 ENST00000263847.1
OSBP
oxysterol binding protein
chr4_+_114214125 0.01 ENST00000509550.1
ANK2
ankyrin 2, neuronal
chr4_+_88896819 0.01 ENST00000237623.7
ENST00000395080.3
ENST00000508233.1
ENST00000360804.4
SPP1
secreted phosphoprotein 1
chr16_+_21244986 0.01 ENST00000311620.5
ANKS4B
ankyrin repeat and sterile alpha motif domain containing 4B
chr10_-_14574705 0.01 ENST00000489100.1
FAM107B
family with sequence similarity 107, member B
chr10_-_61122220 0.01 ENST00000422313.2
ENST00000435852.2
ENST00000442566.3
ENST00000373868.2
ENST00000277705.6
ENST00000373867.3
ENST00000419214.2
FAM13C
family with sequence similarity 13, member C
chrX_-_132095419 0.01 ENST00000370836.2
ENST00000521489.1
HS6ST2
heparan sulfate 6-O-sulfotransferase 2
chr3_-_122102065 0.01 ENST00000479899.1
ENST00000291458.5
ENST00000497726.1
CCDC58
coiled-coil domain containing 58
chr17_-_2614927 0.01 ENST00000435359.1
CLUH
clustered mitochondria (cluA/CLU1) homolog
chr20_-_60294804 0.01 ENST00000317652.1
RP11-429E11.3
Uncharacterized protein
chr17_-_7761172 0.01 ENST00000333775.5
ENST00000575771.1
LSMD1
LSM domain containing 1
chr4_-_80247162 0.01 ENST00000286794.4
NAA11
N(alpha)-acetyltransferase 11, NatA catalytic subunit
chr13_+_35516390 0.01 ENST00000540320.1
ENST00000400445.3
ENST00000310336.4
NBEA
neurobeachin
chr2_-_166060552 0.01 ENST00000283254.7
ENST00000453007.1
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr15_+_81391740 0.01 ENST00000561216.1
C15orf26
chromosome 15 open reading frame 26
chr2_-_3504587 0.00 ENST00000415131.1
ADI1
acireductone dioxygenase 1
chr19_-_38720294 0.00 ENST00000412732.1
ENST00000456296.1
DPF1
D4, zinc and double PHD fingers family 1
chr22_+_45714672 0.00 ENST00000424557.1
FAM118A
family with sequence similarity 118, member A
chr4_-_71705027 0.00 ENST00000545193.1
GRSF1
G-rich RNA sequence binding factor 1
chr16_+_82068830 0.00 ENST00000199936.4
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr9_+_79792410 0.00 ENST00000357409.5
VPS13A
vacuolar protein sorting 13 homolog A (S. cerevisiae)
chr2_-_46844242 0.00 ENST00000281382.6
PIGF
phosphatidylinositol glycan anchor biosynthesis, class F
chr8_+_81397876 0.00 ENST00000430430.1
ZBTB10
zinc finger and BTB domain containing 10
chr15_-_44486632 0.00 ENST00000484674.1
FRMD5
FERM domain containing 5
chr5_+_156696362 0.00 ENST00000377576.3
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr11_+_111126707 0.00 ENST00000280325.4
C11orf53
chromosome 11 open reading frame 53
chr12_+_9144626 0.00 ENST00000543895.1
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chr10_+_77056181 0.00 ENST00000526759.1
ENST00000533822.1
ZNF503-AS1
ZNF503 antisense RNA 1
chr12_+_66218598 0.00 ENST00000541363.1
HMGA2
high mobility group AT-hook 2
chr4_-_71705060 0.00 ENST00000514161.1
GRSF1
G-rich RNA sequence binding factor 1
chr3_-_114343768 0.00 ENST00000393785.2
ZBTB20
zinc finger and BTB domain containing 20
chr17_+_44590076 0.00 ENST00000333412.3
LRRC37A2
leucine rich repeat containing 37, member A2
chr10_+_96522361 0.00 ENST00000371321.3
CYP2C19
cytochrome P450, family 2, subfamily C, polypeptide 19
chr6_-_53013620 0.00 ENST00000259803.7
GCM1
glial cells missing homolog 1 (Drosophila)
chr1_+_110527308 0.00 ENST00000369799.5
AHCYL1
adenosylhomocysteinase-like 1
chr3_+_169539710 0.00 ENST00000340806.6
LRRIQ4
leucine-rich repeats and IQ motif containing 4
chr10_-_4285923 0.00 ENST00000418372.1
ENST00000608792.1
LINC00702
long intergenic non-protein coding RNA 702
chr4_-_168155417 0.00 ENST00000511269.1
ENST00000506697.1
ENST00000512042.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr2_-_233877912 0.00 ENST00000264051.3
NGEF
neuronal guanine nucleotide exchange factor
chr12_+_4714145 0.00 ENST00000545342.1
DYRK4
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chrX_-_117119243 0.00 ENST00000539496.1
ENST00000469946.1
KLHL13
kelch-like family member 13
chr7_-_150020578 0.00 ENST00000478393.1
ACTR3C
ARP3 actin-related protein 3 homolog C (yeast)
chr2_+_171034646 0.00 ENST00000409044.3
ENST00000408978.4
MYO3B
myosin IIIB
chr3_+_171844762 0.00 ENST00000443501.1
FNDC3B
fibronectin type III domain containing 3B
chr5_-_150138061 0.00 ENST00000521533.1
ENST00000424236.1
DCTN4
dynactin 4 (p62)
chr1_+_206516200 0.00 ENST00000295713.5
SRGAP2
SLIT-ROBO Rho GTPase activating protein 2
chr17_+_37856299 0.00 ENST00000269571.5
ERBB2
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
chr18_+_50278430 0.00 ENST00000578080.1
ENST00000582875.1
ENST00000412726.1
DCC
deleted in colorectal carcinoma
chr10_+_1095416 0.00 ENST00000358220.1
WDR37
WD repeat domain 37
chr11_-_76381029 0.00 ENST00000407242.2
ENST00000421973.1
LRRC32
leucine rich repeat containing 32

Network of associatons between targets according to the STRING database.

First level regulatory network of IRX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.0 0.0 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.0 0.1 GO:0071104 response to interleukin-9(GO:0071104)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0004913 interleukin-4 receptor activity(GO:0004913) interleukin-7 receptor activity(GO:0004917)