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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)
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Results for IKZF2
Z-value: 0.76
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Transcription factors associated with IKZF2
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| IKZF2 | hg19_v2_chr2_-_214015111_214015179 | -0.86 | 1.4e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr12_-_68845417 Show fit | 0.65 |
ENST00000542875.1
|
RP11-81H14.2 |
|
| chr19_-_39735646 Show fit | 0.59 |
ENST00000413851.2
|
interferon, lambda 3 |
|
| chr17_-_15469590 Show fit | 0.46 |
ENST00000312127.2
|
CMT duplicated region transcript 1; Uncharacterized protein |
|
| chr21_+_35107346 Show fit | 0.34 |
ENST00000456489.1
|
intersectin 1 (SH3 domain protein) |
|
| chr10_-_10504285 Show fit | 0.32 |
ENST00000602311.1
|
RP11-271F18.4 |
|
| chr14_+_32546274 Show fit | 0.27 |
ENST00000396582.2
|
Rho GTPase activating protein 5 |
|
| chr2_-_119605253 Show fit | 0.26 |
ENST00000295206.6
|
engrailed homeobox 1 |
|
| chr9_-_16705069 Show fit | 0.22 |
ENST00000471301.2
|
basonuclin 2 |
|
| chr9_+_132099158 Show fit | 0.21 |
ENST00000444125.1
|
RP11-65J3.1 |
|
| chr14_-_35591156 Show fit | 0.21 |
ENST00000554361.1
|
protein phosphatase 2, regulatory subunit B'', gamma |
Network of associatons between targets according to the STRING database.
First level regulatory network of IKZF2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.5 | GO:0097500 | receptor localization to nonmotile primary cilium(GO:0097500) |
| 0.0 | 0.5 | GO:1904778 | regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) |
| 0.1 | 0.3 | GO:0061743 | motor learning(GO:0061743) |
| 0.0 | 0.3 | GO:0071638 | negative regulation of monocyte chemotactic protein-1 production(GO:0071638) |
| 0.0 | 0.3 | GO:0032515 | negative regulation of phosphoprotein phosphatase activity(GO:0032515) |
| 0.1 | 0.2 | GO:0060164 | negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of mechanoreceptor differentiation(GO:0045632) regulation of timing of neuron differentiation(GO:0060164) negative regulation of inner ear receptor cell differentiation(GO:2000981) |
| 0.1 | 0.2 | GO:0035508 | positive regulation of myosin-light-chain-phosphatase activity(GO:0035508) |
| 0.1 | 0.2 | GO:0032877 | positive regulation of DNA endoreduplication(GO:0032877) |
| 0.1 | 0.2 | GO:0050902 | leukocyte adhesive activation(GO:0050902) |
| 0.0 | 0.2 | GO:0044837 | assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.5 | GO:0034464 | BBSome(GO:0034464) |
| 0.0 | 0.4 | GO:0008091 | spectrin(GO:0008091) |
| 0.0 | 0.2 | GO:0097149 | centralspindlin complex(GO:0097149) |
| 0.0 | 0.2 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
| 0.0 | 0.1 | GO:0002081 | outer acrosomal membrane(GO:0002081) |
| 0.0 | 0.1 | GO:0005943 | phosphatidylinositol 3-kinase complex, class IA(GO:0005943) |
| 0.0 | 0.1 | GO:0060200 | clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201) |
| 0.0 | 0.0 | GO:0071020 | post-spliceosomal complex(GO:0071020) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | GO:0042731 | PH domain binding(GO:0042731) |
| 0.0 | 0.2 | GO:0005105 | type 1 fibroblast growth factor receptor binding(GO:0005105) |
| 0.0 | 0.2 | GO:0008241 | peptidyl-dipeptidase activity(GO:0008241) |
| 0.0 | 0.2 | GO:0004517 | nitric-oxide synthase activity(GO:0004517) tetrahydrobiopterin binding(GO:0034617) |
| 0.0 | 0.1 | GO:0004766 | spermidine synthase activity(GO:0004766) |
| 0.0 | 0.1 | GO:0055100 | adiponectin binding(GO:0055100) |
| 0.0 | 0.1 | GO:1990948 | ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948) |
| 0.0 | 0.1 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
| 0.0 | 0.1 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 0.0 | 0.1 | GO:0031208 | POZ domain binding(GO:0031208) |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 | Genes involved in Signaling by activated point mutants of FGFR1 |
| 0.0 | 0.1 | REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE | Genes involved in Translocation of ZAP-70 to Immunological synapse |