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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)
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Results for HSF2
Z-value: 1.51
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Transcription factors associated with HSF2
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| HSF2 | hg19_v2_chr6_+_122720681_122720713 | 0.98 | 1.7e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr8_+_38261880 Show fit | 1.30 |
ENST00000527175.1
|
leucine zipper-EF-hand containing transmembrane protein 2 |
|
| chr14_-_52535712 Show fit | 0.76 |
ENST00000216286.5
ENST00000541773.1 |
nidogen 2 (osteonidogen) |
|
| chr2_+_162272605 Show fit | 0.67 |
ENST00000389554.3
|
T-box, brain, 1 |
|
| chr4_+_184427235 Show fit | 0.63 |
ENST00000412117.1
ENST00000434682.2 |
inhibitor of growth family, member 2 |
|
| chr17_-_79817091 Show fit | 0.59 |
ENST00000570907.1
|
prolyl 4-hydroxylase, beta polypeptide |
|
| chr16_+_226658 Show fit | 0.56 |
ENST00000320868.5
ENST00000397797.1 |
hemoglobin, alpha 1 |
|
| chr1_-_67142710 Show fit | 0.51 |
ENST00000502413.2
|
Uncharacterized protein |
|
| chr7_-_86848933 Show fit | 0.51 |
ENST00000423734.1
|
transmembrane protein 243, mitochondrial |
|
| chr20_+_44746939 Show fit | 0.45 |
ENST00000372276.3
|
CD40 molecule, TNF receptor superfamily member 5 |
|
| chr14_-_67859422 Show fit | 0.44 |
ENST00000556532.1
|
pleckstrin 2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of HSF2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.9 | GO:1903750 | regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751) |
| 0.0 | 0.9 | GO:0043268 | positive regulation of potassium ion transport(GO:0043268) |
| 0.3 | 0.8 | GO:0051086 | chaperone mediated protein folding independent of cofactor(GO:0051086) |
| 0.0 | 0.8 | GO:0048488 | synaptic vesicle endocytosis(GO:0048488) |
| 0.1 | 0.7 | GO:0021764 | amygdala development(GO:0021764) |
| 0.1 | 0.6 | GO:0042078 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) |
| 0.1 | 0.6 | GO:0033590 | response to cobalamin(GO:0033590) cellular response to erythropoietin(GO:0036018) |
| 0.1 | 0.6 | GO:0034378 | chylomicron assembly(GO:0034378) |
| 0.0 | 0.6 | GO:0043587 | tongue morphogenesis(GO:0043587) |
| 0.0 | 0.6 | GO:0015671 | oxygen transport(GO:0015671) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.1 | GO:0002199 | zona pellucida receptor complex(GO:0002199) |
| 0.0 | 1.1 | GO:0071682 | endocytic vesicle lumen(GO:0071682) |
| 0.2 | 0.8 | GO:1990769 | proximal neuron projection(GO:1990769) |
| 0.0 | 0.7 | GO:0045095 | keratin filament(GO:0045095) |
| 0.1 | 0.6 | GO:0016222 | procollagen-proline 4-dioxygenase complex(GO:0016222) |
| 0.1 | 0.6 | GO:0043196 | varicosity(GO:0043196) |
| 0.1 | 0.6 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 0.1 | 0.6 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 0.0 | 0.5 | GO:0043189 | NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562) |
| 0.1 | 0.4 | GO:0098575 | lumenal side of lysosomal membrane(GO:0098575) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.3 | GO:0043022 | ribosome binding(GO:0043022) |
| 0.1 | 0.9 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 0.0 | 0.8 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
| 0.0 | 0.7 | GO:0005031 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.0 | 0.7 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.1 | 0.6 | GO:0004656 | procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798) |
| 0.1 | 0.6 | GO:0055131 | C3HC4-type RING finger domain binding(GO:0055131) |
| 0.0 | 0.6 | GO:0005344 | oxygen transporter activity(GO:0005344) |
| 0.1 | 0.5 | GO:0052841 | endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848) |
| 0.0 | 0.4 | GO:0036042 | long-chain fatty acyl-CoA binding(GO:0036042) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.8 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.4 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.0 | 1.0 | REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | Genes involved in Formation of tubulin folding intermediates by CCT/TriC |
| 0.0 | 0.6 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.0 | 0.4 | REACTOME SEMA3A PAK DEPENDENT AXON REPULSION | Genes involved in Sema3A PAK dependent Axon repulsion |
| 0.0 | 0.3 | REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
| 0.0 | 0.3 | REACTOME XENOBIOTICS | Genes involved in Xenobiotics |
| 0.0 | 0.3 | REACTOME PYRIMIDINE CATABOLISM | Genes involved in Pyrimidine catabolism |
| 0.0 | 0.3 | REACTOME PECAM1 INTERACTIONS | Genes involved in PECAM1 interactions |
| 0.0 | 0.3 | REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR | Genes involved in Prostacyclin signalling through prostacyclin receptor |
| 0.0 | 0.1 | REACTOME PURINE CATABOLISM | Genes involved in Purine catabolism |