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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for HOXB8

Z-value: 1.71

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Transcription factors associated with HOXB8

Gene Symbol Gene ID Gene Info
ENSG00000120068.5 homeobox B8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXB8hg19_v2_chr17_-_46690839_466908840.963.9e-02Click!

Activity profile of HOXB8 motif

Sorted Z-values of HOXB8 motif

Promoter Log-likelihood Transcript Gene Gene Info
chrX_-_55208866 1.37 ENST00000545075.1
MT-RNR2-like 10
chr1_+_161494036 1.31 ENST00000309758.4
heat shock 70kDa protein 6 (HSP70B')
chr20_-_29896388 0.94 ENST00000400549.1
defensin, beta 116
chr7_-_27142290 0.93 ENST00000222718.5
homeobox A2
chr8_+_38261880 0.91 ENST00000527175.1
leucine zipper-EF-hand containing transmembrane protein 2
chr19_+_49467232 0.79 ENST00000599784.1
ENST00000594305.1
CTD-2639E6.9
chr1_+_104159999 0.75 ENST00000414303.2
ENST00000423678.1
amylase, alpha 2A (pancreatic)
chr19_-_14992264 0.75 ENST00000327462.2
olfactory receptor, family 7, subfamily A, member 17
chr4_-_118006697 0.74 ENST00000310754.4
translocation associated membrane protein 1-like 1
chr17_-_57229155 0.73 ENST00000584089.1
spindle and kinetochore associated complex subunit 2
chr19_+_18726786 0.72 ENST00000594709.1
transmembrane protein 59-like
chr7_+_26332645 0.70 ENST00000396376.1
sorting nexin 10
chr11_+_122733011 0.66 ENST00000533709.1
cytotoxic and regulatory T cell molecule
chr1_-_238108575 0.64 ENST00000604646.1
MT-RNR2-like 11 (pseudogene)
chr4_+_38511367 0.64 ENST00000507056.1
RP11-213G21.1
chr6_+_26273144 0.63 ENST00000377733.2
histone cluster 1, H2bi
chr4_+_139694701 0.58 ENST00000502606.1
RP11-98O2.1
chr5_-_156362666 0.55 ENST00000406964.1
T-cell immunoglobulin and mucin domain containing 4
chr13_+_28519343 0.53 ENST00000381026.3
ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit pseudogene 2
chr1_-_67142710 0.53 ENST00000502413.2
Uncharacterized protein
chr17_+_22022437 0.52 ENST00000540040.1
MT-RNR2-like 1
chr2_-_236684438 0.52 ENST00000409661.1
Uncharacterized protein
chr6_-_13621126 0.51 ENST00000600057.1
Uncharacterized protein
chr3_-_178103144 0.50 ENST00000417383.1
ENST00000418585.1
ENST00000411727.1
ENST00000439810.1
RP11-33A14.1
chr1_+_28527070 0.49 ENST00000596102.1
AL353354.2
chr15_+_49715293 0.47 ENST00000267843.4
ENST00000560270.1
fibroblast growth factor 7
chr16_+_15489603 0.47 ENST00000568766.1
ENST00000287594.7
Uncharacterized protein
MPV17 mitochondrial membrane protein-like
chr18_+_63273310 0.47 ENST00000579862.1
RP11-775G23.1
chr10_+_13141585 0.46 ENST00000378764.2
optineurin
chr12_+_22852791 0.46 ENST00000413794.2
RP11-114G22.1
chr5_+_59726565 0.46 ENST00000412930.2
FKSG52
chr19_-_52551814 0.44 ENST00000594154.1
ENST00000598745.1
ENST00000597273.1
zinc finger protein 432
chr12_-_109025849 0.44 ENST00000228463.6
selectin P ligand
chr8_-_38008783 0.44 ENST00000276449.4
steroidogenic acute regulatory protein
chr5_+_53686658 0.42 ENST00000512618.1
long intergenic non-protein coding RNA 1033
chr12_-_118628315 0.42 ENST00000540561.1
TAO kinase 3
chr5_-_140013224 0.42 ENST00000498971.2
CD14 molecule
chr14_-_55907334 0.42 ENST00000247219.5
TATA box binding protein like 2
chr4_+_75230853 0.42 ENST00000244869.2
epiregulin
chr14_-_62217779 0.40 ENST00000554254.1
HIF1A antisense RNA 2
chr12_+_54402790 0.39 ENST00000040584.4
homeobox C8
chr4_-_112993808 0.39 ENST00000511219.1
RP11-269F21.3
chr8_-_93978346 0.38 ENST00000523580.1
triple QxxK/R motif containing
chr17_-_45266542 0.38 ENST00000531206.1
ENST00000527547.1
ENST00000446365.2
ENST00000575483.1
ENST00000066544.3
cell division cycle 27
chr15_-_60683326 0.38 ENST00000559350.1
ENST00000558986.1
ENST00000560389.1
annexin A2
chr4_-_185275104 0.38 ENST00000317596.3
RP11-290F5.2
chr2_+_217277271 0.37 ENST00000425815.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
chr10_+_13142225 0.37 ENST00000378747.3
optineurin
chr14_-_34931458 0.37 ENST00000298130.4
serine palmitoyltransferase, small subunit A
chr8_-_67874805 0.37 ENST00000563496.1
transcription factor 24
chr11_+_122709200 0.37 ENST00000227348.4
cytotoxic and regulatory T cell molecule
chr22_+_50312379 0.36 ENST00000407217.3
ENST00000403427.3
cysteine-rich with EGF-like domains 2
chr4_+_144354644 0.36 ENST00000512843.1
GRB2-associated binding protein 1
chr1_-_149783914 0.36 ENST00000369167.1
ENST00000427880.2
ENST00000545683.1
histone cluster 2, H2bf
chr1_+_112016414 0.35 ENST00000343534.5
ENST00000369718.3
chromosome 1 open reading frame 162
chr8_-_79717750 0.34 ENST00000263851.4
ENST00000379113.2
interleukin 7
chr19_+_12203069 0.34 ENST00000430298.2
ENST00000339302.4
zinc finger family member 788
Zinc finger protein 788
chr15_-_80263506 0.34 ENST00000335661.6
BCL2-related protein A1
chr15_+_78830023 0.34 ENST00000599596.1
HCG2005369; Uncharacterized protein
chrX_-_1331527 0.34 ENST00000381567.3
ENST00000381566.1
ENST00000400841.2
cytokine receptor-like factor 2
chrX_-_46404811 0.34 ENST00000518708.1
ENST00000523374.1
zinc finger protein 674
chr11_+_29181503 0.34 ENST00000530960.1
RP11-466I1.1
chr13_+_21714913 0.33 ENST00000450573.1
ENST00000467636.1
Sin3A-associated protein, 18kDa
chr16_+_15489629 0.33 ENST00000396385.3
MPV17 mitochondrial membrane protein-like
chr4_+_71600144 0.33 ENST00000502653.1
RUN and FYVE domain containing 3
chr2_-_99871570 0.33 ENST00000333017.2
ENST00000409679.1
ENST00000423306.1
lysozyme G-like 2
chr12_-_79849240 0.33 ENST00000550268.1
RP1-78O14.1
chr2_-_27886676 0.33 ENST00000337768.5
suppressor of Ty 7 (S. cerevisiae)-like
chr17_+_57297807 0.33 ENST00000284116.4
ENST00000581140.1
ENST00000581276.1
glycerophosphodiester phosphodiesterase domain containing 1
chr8_-_101719159 0.32 ENST00000520868.1
ENST00000522658.1
poly(A) binding protein, cytoplasmic 1
chr15_-_38519066 0.32 ENST00000561320.1
ENST00000561161.1
RP11-346D14.1
chr2_+_182850551 0.32 ENST00000452904.1
ENST00000409137.3
ENST00000280295.3
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr4_+_100737954 0.32 ENST00000296414.7
ENST00000512369.1
dual adaptor of phosphotyrosine and 3-phosphoinositides
chr13_+_30002846 0.32 ENST00000542829.1
microtubule associated tumor suppressor candidate 2
chr19_+_58694742 0.32 ENST00000597528.1
ENST00000594839.1
zinc finger protein 274
chr4_-_176828307 0.32 ENST00000513365.1
ENST00000513667.1
ENST00000503563.1
glycoprotein M6A
chr8_+_39972170 0.32 ENST00000521257.1
RP11-359E19.2
chr3_+_49977523 0.31 ENST00000422955.1
RNA binding motif protein 6
chr12_+_43086018 0.30 ENST00000550177.1
RP11-25I15.3
chr5_+_42756903 0.30 ENST00000361970.5
ENST00000388827.4
coiled-coil domain containing 152
chr8_-_65730127 0.30 ENST00000522106.1
RP11-1D12.2
chr3_+_49977490 0.30 ENST00000539992.1
RNA binding motif protein 6
chr7_+_107224364 0.30 ENST00000491150.1
B-cell receptor-associated protein 29
chr8_-_108510224 0.29 ENST00000517746.1
ENST00000297450.3
angiopoietin 1
chr19_-_52552051 0.29 ENST00000221315.5
zinc finger protein 432
chr7_-_77325545 0.29 ENST00000447009.1
ENST00000416650.1
ENST00000440088.1
ENST00000430801.1
ENST00000398043.2
RSBN1L antisense RNA 1
chr12_-_76461249 0.29 ENST00000551524.1
nucleosome assembly protein 1-like 1
chr1_-_206288647 0.29 ENST00000331555.5
chromosome 1 open reading frame 186
chr15_-_76352069 0.29 ENST00000305435.10
ENST00000563910.1
neuregulin 4
chr8_-_81083618 0.29 ENST00000520795.1
tumor protein D52
chr6_+_63921351 0.28 ENST00000370659.1
FK506 binding protein 1C
chr4_-_111536534 0.28 ENST00000503456.1
ENST00000513690.1
RP11-380D23.2
chr4_-_123542224 0.28 ENST00000264497.3
interleukin 21
chr12_+_14956506 0.28 ENST00000330828.2
chromosome 12 open reading frame 60
chr3_+_119298280 0.27 ENST00000481816.1
ADP-ribosylarginine hydrolase
chr12_-_14967095 0.27 ENST00000316048.2
single-pass membrane protein with coiled-coil domains 3
chr20_+_34802295 0.27 ENST00000432603.1
erythrocyte membrane protein band 4.1-like 1
chr4_+_39408470 0.27 ENST00000257408.4
klotho beta
chr19_-_51920952 0.27 ENST00000356298.5
ENST00000339313.5
ENST00000529627.1
ENST00000439889.2
ENST00000353836.5
ENST00000432469.2
sialic acid binding Ig-like lectin 10
chr9_+_129097479 0.27 ENST00000402437.2
multivesicular body subunit 12B
chr7_-_32529973 0.27 ENST00000410044.1
ENST00000409987.1
ENST00000409782.1
ENST00000450169.2
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr15_-_83224682 0.27 ENST00000562833.1
RP11-152F13.10
chr3_-_45837959 0.27 ENST00000353278.4
ENST00000456124.2
solute carrier family 6 (proline IMINO transporter), member 20
chr3_-_45838011 0.27 ENST00000358525.4
ENST00000413781.1
solute carrier family 6 (proline IMINO transporter), member 20
chr2_-_188312971 0.27 ENST00000410068.1
ENST00000447403.1
ENST00000410102.1
calcitonin receptor-like
chr10_+_5488564 0.27 ENST00000449083.1
ENST00000380359.3
neuroepithelial cell transforming 1
chr9_-_69229650 0.27 ENST00000416428.1
COBW domain containing 6
chrX_+_46404928 0.26 ENST00000421685.2
ENST00000609887.1
ZNF674 antisense RNA 1 (head to head)
chr15_-_28778117 0.26 ENST00000525590.2
ENST00000329523.6
golgin A8 family, member G
chr3_+_87276407 0.26 ENST00000471660.1
ENST00000263780.4
ENST00000494980.1
charged multivesicular body protein 2B
chr10_+_13141441 0.26 ENST00000263036.5
optineurin
chr3_+_159557637 0.26 ENST00000445224.2
schwannomin interacting protein 1
chr8_-_91618285 0.26 ENST00000517505.1
long intergenic non-protein coding RNA 1030
chr1_-_209957882 0.26 ENST00000294811.1
chromosome 1 open reading frame 74
chr20_-_55934878 0.26 ENST00000543500.1
MT-RNR2-like 3
chr17_-_8286484 0.26 ENST00000582556.1
ENST00000584164.1
ENST00000293842.5
ENST00000584343.1
ENST00000578812.1
ENST00000583011.1
ribosomal protein L26
chr8_-_11996586 0.26 ENST00000333796.3
ubiquitin specific peptidase 17-like family member 2
chr12_-_100656134 0.26 ENST00000548313.1
DEP domain containing 4
chr14_+_51955831 0.25 ENST00000356218.4
FERM domain containing 6
chr4_-_70626430 0.25 ENST00000310613.3
sulfotransferase family, cytosolic, 1B, member 1
chr22_+_50312316 0.25 ENST00000328268.4
cysteine-rich with EGF-like domains 2
chr4_+_71600063 0.25 ENST00000513597.1
RUN and FYVE domain containing 3
chr16_+_81528948 0.25 ENST00000539778.2
c-Maf inducing protein
chr3_+_177545563 0.25 ENST00000434309.1
RP11-91K9.1
chr19_+_35417939 0.25 ENST00000601142.1
ENST00000426813.2
zinc finger protein 30
chr1_-_6420737 0.25 ENST00000541130.1
ENST00000377845.3
acyl-CoA thioesterase 7
chr4_-_69817481 0.25 ENST00000251566.4
UDP glucuronosyltransferase 2 family, polypeptide A3
chr15_+_28623784 0.25 ENST00000526619.2
ENST00000337838.7
ENST00000532622.2
golgin A8 family, member F
chr14_-_36645674 0.25 ENST00000556013.2
papillary thyroid carcinoma susceptibility candidate 3 (non-protein coding)
chr1_-_53686261 0.25 ENST00000294360.4
chromosome 1 open reading frame 123
chr2_-_27886460 0.24 ENST00000404798.2
ENST00000405491.1
ENST00000464789.2
ENST00000406540.1
suppressor of Ty 7 (S. cerevisiae)-like
chr4_+_165878100 0.24 ENST00000513876.2
family with sequence similarity 218, member A
chr1_+_229440129 0.24 ENST00000366688.3
S-phase response (cyclin related)
chr1_+_198608146 0.24 ENST00000367376.2
ENST00000352140.3
ENST00000594404.1
ENST00000598951.1
ENST00000530727.1
ENST00000442510.2
ENST00000367367.4
ENST00000348564.6
ENST00000367364.1
ENST00000413409.2
protein tyrosine phosphatase, receptor type, C
chr4_+_69962212 0.24 ENST00000508661.1
UDP glucuronosyltransferase 2 family, polypeptide B7
chr10_+_52152766 0.24 ENST00000596442.1
Uncharacterized protein
chr8_-_30002179 0.24 ENST00000320542.3
membrane bound O-acyltransferase domain containing 4
chr19_-_48753028 0.24 ENST00000522431.1
caspase recruitment domain family, member 8
chr1_-_54411255 0.24 ENST00000371377.3
heat shock protein family B (small), member 11
chr3_-_148939598 0.24 ENST00000455472.3
ceruloplasmin (ferroxidase)
chr5_+_159848854 0.24 ENST00000517480.1
ENST00000520452.1
ENST00000393964.1
pituitary tumor-transforming 1
chr11_+_122753391 0.24 ENST00000307257.6
ENST00000227349.2
chromosome 11 open reading frame 63
chr12_+_20963647 0.23 ENST00000381545.3
solute carrier organic anion transporter family, member 1B3
chr2_+_234637754 0.23 ENST00000482026.1
ENST00000609767.1
UDP glucuronosyltransferase 1 family, polypeptide A3
UDP glucuronosyltransferase 1 family, polypeptide A8
chr16_-_68034470 0.23 ENST00000412757.2
dipeptidase 2
chr7_+_16793160 0.23 ENST00000262067.4
tetraspanin 13
chr7_-_23145288 0.23 ENST00000419813.1
KLHL7 antisense RNA 1 (head to head)
chr2_-_74735707 0.23 ENST00000233630.6
polycomb group ring finger 1
chr11_-_123525289 0.23 ENST00000392770.2
ENST00000299333.3
ENST00000530277.1
sodium channel, voltage-gated, type III, beta subunit
chr22_+_20105259 0.23 ENST00000416427.1
ENST00000421656.1
ENST00000423859.1
ENST00000418705.2
RAN binding protein 1
chr12_+_128399965 0.23 ENST00000540882.1
ENST00000542089.1
long intergenic non-protein coding RNA 507
chr16_-_20338748 0.23 ENST00000575582.1
ENST00000341642.5
ENST00000381362.4
ENST00000572347.1
ENST00000572478.1
ENST00000302555.5
glycoprotein 2 (zymogen granule membrane)
chr16_+_84801852 0.23 ENST00000569925.1
ENST00000567526.1
ubiquitin specific peptidase 10
chr2_+_182850743 0.23 ENST00000409702.1
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr20_+_10199566 0.23 ENST00000430336.1
synaptosomal-associated protein, 25kDa
chr5_+_176692466 0.23 ENST00000508029.1
ENST00000503056.1
nuclear receptor binding SET domain protein 1
chr15_-_66790146 0.23 ENST00000316634.5
small nuclear RNA activating complex, polypeptide 5, 19kDa
chr9_+_128509624 0.23 ENST00000342287.5
ENST00000373487.4
pre-B-cell leukemia homeobox 3
chr5_-_78809950 0.23 ENST00000334082.6
homer homolog 1 (Drosophila)
chr16_-_18462221 0.22 ENST00000528301.1
LOC339047 protein; Nuclear pore complex-interacting protein family member A3; Nuclear pore complex-interacting protein family member A5; Protein PKD1P1
chr10_+_13142075 0.22 ENST00000378757.2
ENST00000430081.1
ENST00000378752.3
ENST00000378748.3
optineurin
chr10_+_35484793 0.22 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
cAMP responsive element modulator
chr15_+_23255242 0.22 ENST00000450802.3
golgin A8 family, member I
chr5_+_89770664 0.22 ENST00000503973.1
ENST00000399107.1
polymerase (RNA) III (DNA directed) polypeptide G (32kD)
chr15_+_49715449 0.22 ENST00000560979.1
fibroblast growth factor 7
chr6_+_130339710 0.22 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
l(3)mbt-like 3 (Drosophila)
chr8_+_128747757 0.22 ENST00000517291.1
v-myc avian myelocytomatosis viral oncogene homolog
chr3_-_64009658 0.22 ENST00000394431.2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
chr14_+_78174414 0.21 ENST00000557342.1
ENST00000238688.5
ENST00000557623.1
ENST00000557431.1
ENST00000556831.1
ENST00000556375.1
ENST00000553981.1
SRA stem-loop interacting RNA binding protein
chr12_+_16109519 0.21 ENST00000526530.1
deoxyribose-phosphate aldolase (putative)
chr8_-_93978309 0.21 ENST00000517858.1
ENST00000378861.5
triple QxxK/R motif containing
chr19_+_35417844 0.21 ENST00000601957.1
zinc finger protein 30
chr15_-_72521017 0.21 ENST00000561609.1
pyruvate kinase, muscle
chr11_-_62572901 0.21 ENST00000439713.2
ENST00000531131.1
ENST00000530875.1
ENST00000531709.2
ENST00000294172.2
nuclear RNA export factor 1
chr10_-_22292613 0.21 ENST00000376980.3
DnaJ (Hsp40) homolog, subfamily C, member 1
chr2_+_27237615 0.21 ENST00000458529.1
ENST00000402218.1
microtubule-associated protein, RP/EB family, member 3
chr4_+_48833312 0.21 ENST00000508293.1
ENST00000513391.2
OCIA domain containing 1
chr4_-_23735183 0.21 ENST00000507666.1
RP11-380P13.2
chr12_+_98909260 0.21 ENST00000556029.1
thymopoietin
chr2_+_201450591 0.21 ENST00000374700.2
aldehyde oxidase 1
chr16_-_24942411 0.21 ENST00000571843.1
Rho GTPase activating protein 17
chr19_+_50180409 0.21 ENST00000391851.4
protein arginine methyltransferase 1
chr3_+_57882061 0.21 ENST00000461354.1
ENST00000466255.1
sarcolemma associated protein
chr14_+_35591928 0.21 ENST00000605870.1
ENST00000557404.3
KIAA0391
chr22_-_29196030 0.21 ENST00000405219.3
X-box binding protein 1
chr15_+_92006567 0.21 ENST00000554333.1
RP11-661P17.1
chr10_+_69869237 0.21 ENST00000373675.3
myopalladin
chr14_+_97925151 0.21 ENST00000554862.1
ENST00000554260.1
ENST00000499910.2
CTD-2506J14.1
chr4_-_155533787 0.21 ENST00000407946.1
ENST00000405164.1
ENST00000336098.3
ENST00000393846.2
ENST00000404648.3
ENST00000443553.1
fibrinogen gamma chain
chr5_-_10761206 0.20 ENST00000432074.2
ENST00000230895.6
death-associated protein
chr17_-_17184605 0.20 ENST00000268717.5
COP9 signalosome subunit 3
chr17_-_4938712 0.20 ENST00000254853.5
ENST00000424747.1
solute carrier family 52 (riboflavin transporter), member 1
chr2_+_201997676 0.20 ENST00000462763.1
ENST00000479953.2
CASP8 and FADD-like apoptosis regulator
chrX_-_19988382 0.20 ENST00000356980.3
ENST00000379687.3
ENST00000379682.4
chromosome X open reading frame 23
chr12_+_64798095 0.20 ENST00000332707.5
exportin, tRNA
chr13_+_30002741 0.20 ENST00000380808.2
microtubule associated tumor suppressor candidate 2
chr19_-_52598958 0.20 ENST00000594440.1
ENST00000426391.2
ENST00000389534.4
zinc finger protein 841
chr5_-_125930929 0.20 ENST00000553117.1
ENST00000447989.2
ENST00000409134.3
aldehyde dehydrogenase 7 family, member A1
chr11_+_94300474 0.20 ENST00000299001.6
piwi-like RNA-mediated gene silencing 4
chr19_+_2819854 0.20 ENST00000317243.5
zinc finger protein 554

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0021569 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.2 1.3 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.2 0.7 GO:0060437 lung growth(GO:0060437)
0.2 0.8 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.1 1.3 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.4 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.1 0.4 GO:0017143 insecticide metabolic process(GO:0017143) cellular response to luteinizing hormone stimulus(GO:0071373)
0.1 0.1 GO:0048193 Golgi vesicle transport(GO:0048193)
0.1 0.7 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 0.3 GO:0071586 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.1 1.0 GO:0002857 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.1 0.2 GO:0007387 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.1 0.2 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
0.1 0.2 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1 0.4 GO:0071725 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.1 0.2 GO:0060691 epithelial cell differentiation involved in salivary gland development(GO:0060690) epithelial cell maturation involved in salivary gland development(GO:0060691) regulation of plasma cell differentiation(GO:1900098) positive regulation of plasma cell differentiation(GO:1900100) regulation of lactation(GO:1903487) positive regulation of lactation(GO:1903489)
0.1 0.3 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.1 0.2 GO:0036116 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.1 0.3 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.1 0.2 GO:0052363 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.1 0.2 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.1 0.4 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 0.2 GO:0031296 B cell costimulation(GO:0031296)
0.1 0.2 GO:0032053 ciliary basal body organization(GO:0032053)
0.1 0.2 GO:0043605 cellular amide catabolic process(GO:0043605)
0.1 0.7 GO:0015824 proline transport(GO:0015824)
0.1 0.2 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.1 0.2 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.1 0.2 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 0.2 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.1 0.2 GO:0090096 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.1 0.3 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.1 0.2 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.1 0.2 GO:0046110 xanthine metabolic process(GO:0046110)
0.0 0.3 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.2 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.4 GO:0003383 apical constriction(GO:0003383)
0.0 0.2 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.2 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0 0.2 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405)
0.0 0.4 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.4 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.1 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
0.0 0.2 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0 0.5 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.0 0.2 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.2 GO:0002378 immunoglobulin biosynthetic process(GO:0002378) hematopoietic stem cell migration(GO:0035701)
0.0 0.1 GO:0002101 tRNA wobble cytosine modification(GO:0002101) RNA repair(GO:0042245)
0.0 0.3 GO:0019075 virus maturation(GO:0019075)
0.0 0.2 GO:0032796 uropod organization(GO:0032796)
0.0 0.6 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.3 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 0.2 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.2 GO:1904501 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.0 0.2 GO:0034255 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.0 0.3 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.3 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.3 GO:1902231 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164) positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.4 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.3 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.2 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.2 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.1 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.2 GO:1904685 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209) positive regulation of metalloendopeptidase activity(GO:1904685)
0.0 0.6 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112)
0.0 0.1 GO:0050757 thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.3 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.2 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
0.0 0.3 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.1 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.2 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.2 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.2 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.1 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.2 GO:0006789 bilirubin conjugation(GO:0006789)
0.0 0.1 GO:0043486 histone exchange(GO:0043486)
0.0 0.4 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.1 GO:0048478 replication fork protection(GO:0048478)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.2 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.0 0.1 GO:0048769 sarcomerogenesis(GO:0048769)
0.0 0.3 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.0 0.1 GO:1902904 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.0 0.1 GO:0014004 microglia differentiation(GO:0014004) microglia development(GO:0014005) cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.1 GO:0036367 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.0 0.2 GO:0001712 ectoderm formation(GO:0001705) ectodermal cell fate commitment(GO:0001712)
0.0 0.1 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.1 GO:0090166 regulation of Schwann cell differentiation(GO:0014038) Golgi disassembly(GO:0090166)
0.0 0.3 GO:0016081 synaptic vesicle docking(GO:0016081)
0.0 0.1 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.1 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 0.1 GO:0061461 lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
0.0 0.2 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.0 0.3 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.1 GO:0090410 malonate catabolic process(GO:0090410)
0.0 0.2 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.1 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.3 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.0 0.2 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.2 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.9 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.2 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.0 0.1 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.7 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.1 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0031508 pericentric heterochromatin assembly(GO:0031508) regulation of chromosome condensation(GO:0060623)
0.0 0.4 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.0 GO:0035696 monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437)
0.0 0.3 GO:0051451 myoblast migration(GO:0051451)
0.0 0.3 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.0 0.3 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.1 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.0 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.1 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.2 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.0 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 0.2 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.1 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.3 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.1 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.0 0.1 GO:1904386 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.0 0.0 GO:0045349 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.0 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.0 0.2 GO:0018406 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.3 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.3 GO:0032196 transposition(GO:0032196)
0.0 0.1 GO:0050893 sensory processing(GO:0050893)
0.0 0.2 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.2 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.0 0.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.1 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.6 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.1 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.2 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0 0.2 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.2 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.2 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.1 GO:0060334 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.3 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.1 GO:0042090 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.1 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.0 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.0 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.2 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 0.1 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.5 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.4 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.4 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.2 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.3 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 0.5 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.1 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 0.0 GO:0060018 astrocyte fate commitment(GO:0060018)
0.0 0.4 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.4 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.9 GO:0010965 regulation of mitotic sister chromatid separation(GO:0010965)
0.0 0.3 GO:0048846 axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284)
0.0 0.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1902912 pyruvate kinase complex(GO:1902912)
0.1 0.5 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.1 0.1 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.1 0.7 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.2 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.2 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.2 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.0 0.4 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993)
0.0 0.8 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.8 GO:0030914 STAGA complex(GO:0030914)
0.0 0.2 GO:0071547 piP-body(GO:0071547)
0.0 0.2 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.0 0.3 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.4 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.4 GO:0005827 polar microtubule(GO:0005827)
0.0 0.1 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.1 GO:0070985 TFIIK complex(GO:0070985)
0.0 0.1 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.0 0.2 GO:0097513 actomyosin contractile ring(GO:0005826) myosin II filament(GO:0097513)
0.0 0.1 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.5 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.3 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.3 GO:0061574 ASAP complex(GO:0061574)
0.0 0.4 GO:0033269 internode region of axon(GO:0033269)
0.0 0.1 GO:0097422 tubular endosome(GO:0097422)
0.0 0.1 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.1 GO:0034684 integrin alphav-beta5 complex(GO:0034684)
0.0 0.3 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.4 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 0.2 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.1 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.2 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.4 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 1.2 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.4 GO:0034709 methylosome(GO:0034709)
0.0 0.2 GO:1990907 Scrib-APC-beta-catenin complex(GO:0034750) beta-catenin-TCF7L2 complex(GO:0070369) beta-catenin-TCF complex(GO:1990907)
0.0 0.1 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.0 0.1 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.4 GO:0097342 ripoptosome(GO:0097342)
0.0 0.1 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.1 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.0 0.1 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.1 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.1 GO:0097449 astrocyte projection(GO:0097449)
0.0 0.5 GO:0071437 invadopodium(GO:0071437)
0.0 0.5 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.1 GO:0005873 plus-end kinesin complex(GO:0005873)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.1 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.0 GO:0042565 RNA nuclear export complex(GO:0042565)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 1.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.5 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.2 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.1 GO:0036128 CatSper complex(GO:0036128)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.1 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.3 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.4 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.1 0.2 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.1 0.3 GO:0008422 beta-glucosidase activity(GO:0008422)
0.1 0.6 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.2 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 0.4 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.3 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.0 0.3 GO:0032089 NACHT domain binding(GO:0032089)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.2 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.3 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.2 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.6 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.2 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.1 GO:0050473 linoleate 13S-lipoxygenase activity(GO:0016165) arachidonate 15-lipoxygenase activity(GO:0050473)
0.0 0.1 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.0 0.1 GO:0051870 methotrexate binding(GO:0051870)
0.0 0.2 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.3 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.9 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.2 GO:0034584 piRNA binding(GO:0034584)
0.0 0.2 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0043337 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.0 0.2 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.2 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.1 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.2 GO:0031208 POZ domain binding(GO:0031208)
0.0 1.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.3 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.2 GO:0042806 fucose binding(GO:0042806)
0.0 0.2 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.0 0.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.3 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.2 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.6 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.2 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.2 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.0 0.2 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.0 0.4 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.1 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493) C-C chemokine binding(GO:0019957)
0.0 0.1 GO:0090409 malonyl-CoA synthetase activity(GO:0090409)
0.0 0.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.8 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.9 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.2 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.2 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.1 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.2 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.2 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)
0.0 0.3 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.1 GO:0005115 receptor tyrosine kinase-like orphan receptor binding(GO:0005115) chemoattractant activity involved in axon guidance(GO:1902379)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.3 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.1 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.1 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.1 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.0 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.0 0.1 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.4 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:0004803 transposase activity(GO:0004803)
0.0 0.0 GO:0080130 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.1 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.0 0.1 GO:0005289 high-affinity basic amino acid transmembrane transporter activity(GO:0005287) high-affinity arginine transmembrane transporter activity(GO:0005289) high-affinity lysine transmembrane transporter activity(GO:0005292)
0.0 0.1 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 0.0 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.4 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.0 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.3 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.3 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.2 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.4 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.1 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 1.0 GO:0043022 ribosome binding(GO:0043022)
0.0 0.0 GO:0047017 geranylgeranyl reductase activity(GO:0045550) prostaglandin-F synthase activity(GO:0047017)
0.0 0.1 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.0 PID MYC PATHWAY C-MYC pathway
0.0 0.9 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.4 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.1 0.8 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.7 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.5 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.3 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.0 0.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 1.1 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.5 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 0.3 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.7 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.2 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.2 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.5 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.8 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.3 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.1 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane