Project
A549 cells infected with IAV Analysis Results (GEO series: GSE147507)
Navigation
Downloads
Results for HOXB8
Z-value: 1.71
Motif logo
Transcription factors associated with HOXB8
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| HOXB8 | hg19_v2_chr17_-_46690839_46690884 | 0.96 | 3.9e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chrX_-_55208866 Show fit | 1.37 |
ENST00000545075.1
|
MT-RNR2-like 10 |
|
| chr1_+_161494036 Show fit | 1.31 |
ENST00000309758.4
|
heat shock 70kDa protein 6 (HSP70B') |
|
| chr20_-_29896388 Show fit | 0.94 |
ENST00000400549.1
|
defensin, beta 116 |
|
| chr7_-_27142290 Show fit | 0.93 |
ENST00000222718.5
|
homeobox A2 |
|
| chr8_+_38261880 Show fit | 0.91 |
ENST00000527175.1
|
leucine zipper-EF-hand containing transmembrane protein 2 |
|
| chr19_+_49467232 Show fit | 0.79 |
ENST00000599784.1
ENST00000594305.1 |
CTD-2639E6.9 |
|
| chr1_+_104159999 Show fit | 0.75 |
ENST00000414303.2
ENST00000423678.1 |
amylase, alpha 2A (pancreatic) |
|
| chr19_-_14992264 Show fit | 0.75 |
ENST00000327462.2
|
olfactory receptor, family 7, subfamily A, member 17 |
|
| chr4_-_118006697 Show fit | 0.74 |
ENST00000310754.4
|
translocation associated membrane protein 1-like 1 |
|
| chr17_-_57229155 Show fit | 0.73 |
ENST00000584089.1
|
spindle and kinetochore associated complex subunit 2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of HOXB8
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.3 | GO:0010286 | heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370) |
| 0.1 | 1.3 | GO:0001920 | negative regulation of receptor recycling(GO:0001920) |
| 0.1 | 1.0 | GO:0002857 | positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860) |
| 0.3 | 0.9 | GO:0021569 | rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284) |
| 0.0 | 0.9 | GO:0050911 | detection of chemical stimulus involved in sensory perception of smell(GO:0050911) |
| 0.0 | 0.9 | GO:0010965 | regulation of mitotic sister chromatid separation(GO:0010965) |
| 0.2 | 0.8 | GO:0010730 | negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) |
| 0.2 | 0.7 | GO:0060437 | lung growth(GO:0060437) |
| 0.1 | 0.7 | GO:0044245 | polysaccharide digestion(GO:0044245) |
| 0.1 | 0.7 | GO:0015824 | proline transport(GO:0015824) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.3 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.0 | 1.2 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.0 | 0.8 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 0.0 | 0.8 | GO:0030914 | STAGA complex(GO:0030914) |
| 0.1 | 0.7 | GO:0031313 | extrinsic component of endosome membrane(GO:0031313) |
| 0.1 | 0.5 | GO:0000275 | mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) |
| 0.0 | 0.5 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
| 0.0 | 0.5 | GO:0071437 | invadopodium(GO:0071437) |
| 0.0 | 0.5 | GO:0005838 | proteasome regulatory particle(GO:0005838) |
| 0.0 | 0.5 | GO:0044295 | axonal growth cone(GO:0044295) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.3 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
| 0.0 | 1.0 | GO:0043022 | ribosome binding(GO:0043022) |
| 0.0 | 0.9 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.0 | 0.9 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.2 | 0.8 | GO:0004556 | alpha-amylase activity(GO:0004556) |
| 0.0 | 0.8 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.1 | 0.6 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
| 0.0 | 0.6 | GO:0036310 | annealing helicase activity(GO:0036310) |
| 0.0 | 0.6 | GO:0005328 | neurotransmitter:sodium symporter activity(GO:0005328) |
| 0.1 | 0.4 | GO:0016019 | peptidoglycan receptor activity(GO:0016019) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.0 | PID MYC PATHWAY | C-MYC pathway |
| 0.0 | 0.9 | SIG PIP3 SIGNALING IN B LYMPHOCYTES | Genes related to PIP3 signaling in B lymphocytes |
| 0.0 | 0.8 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.0 | 0.4 | SA FAS SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
| 0.0 | 0.2 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.2 | REACTOME BETA DEFENSINS | Genes involved in Beta defensins |
| 0.0 | 1.1 | REACTOME SHC1 EVENTS IN ERBB4 SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |
| 0.1 | 0.8 | REACTOME DIGESTION OF DIETARY CARBOHYDRATE | Genes involved in Digestion of dietary carbohydrate |
| 0.0 | 0.8 | REACTOME PACKAGING OF TELOMERE ENDS | Genes involved in Packaging Of Telomere Ends |
| 0.0 | 0.7 | REACTOME ACTIVATED POINT MUTANTS OF FGFR2 | Genes involved in Activated point mutants of FGFR2 |
| 0.0 | 0.7 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |
| 0.0 | 0.5 | REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
| 0.0 | 0.5 | REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX | Genes involved in TRAF6 mediated induction of TAK1 complex |
| 0.0 | 0.5 | REACTOME STEROID HORMONES | Genes involved in Steroid hormones |
| 0.0 | 0.4 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |