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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for HOXB13

Z-value: 0.63

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Transcription factors associated with HOXB13

Gene Symbol Gene ID Gene Info
ENSG00000159184.7 homeobox B13

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXB13hg19_v2_chr17_-_46806540_468065580.937.4e-02Click!

Activity profile of HOXB13 motif

Sorted Z-values of HOXB13 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_27782788 0.36 ENST00000359465.4
histone cluster 1, H2bm
chr6_-_27782548 0.36 ENST00000333151.3
histone cluster 1, H2aj
chr16_+_30669720 0.34 ENST00000356166.6
fibrosin
chr5_-_140053152 0.31 ENST00000542735.1
DND microRNA-mediated repression inhibitor 1
chr2_-_176046391 0.29 ENST00000392541.3
ENST00000409194.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr1_-_149783914 0.29 ENST00000369167.1
ENST00000427880.2
ENST00000545683.1
histone cluster 2, H2bf
chr2_+_74685413 0.27 ENST00000233615.2
WW domain binding protein 1
chr5_-_126409159 0.23 ENST00000607731.1
ENST00000535381.1
ENST00000296662.5
ENST00000509733.3
chromosome 5 open reading frame 63
chr16_-_2205352 0.22 ENST00000563192.1
RP11-304L19.5
chr12_-_52715179 0.22 ENST00000293670.3
keratin 83
chr12_+_70219052 0.22 ENST00000552032.2
ENST00000547771.2
myelin regulatory factor-like
chr17_-_46806540 0.20 ENST00000290295.7
homeobox B13
chr19_+_56154913 0.20 ENST00000270451.5
ENST00000588537.1
zinc finger protein 581
chr2_-_190044480 0.20 ENST00000374866.3
collagen, type V, alpha 2
chrM_-_14670 0.16 ENST00000361681.2
mitochondrially encoded NADH dehydrogenase 6
chr2_+_74685527 0.16 ENST00000393972.3
ENST00000409737.1
ENST00000428943.1
WW domain binding protein 1
chr19_+_35634146 0.16 ENST00000586063.1
ENST00000270310.2
ENST00000588265.1
FXYD domain containing ion transport regulator 7
chr3_-_114790179 0.15 ENST00000462705.1
zinc finger and BTB domain containing 20
chr11_+_47279155 0.15 ENST00000444396.1
ENST00000457932.1
ENST00000412937.1
nuclear receptor subfamily 1, group H, member 3
chr18_-_52989525 0.14 ENST00000457482.3
transcription factor 4
chr17_-_73663245 0.13 ENST00000584999.1
ENST00000317905.5
ENST00000420326.2
ENST00000340830.5
RecQ protein-like 5
chr11_+_63606373 0.12 ENST00000402010.2
ENST00000315032.8
ENST00000377809.4
ENST00000413835.2
ENST00000377810.3
MAP/microtubule affinity-regulating kinase 2
chr22_-_38240412 0.11 ENST00000215941.4
ankyrin repeat domain 54
chr17_-_73663168 0.11 ENST00000578201.1
ENST00000423245.2
RecQ protein-like 5
chr3_+_89156799 0.10 ENST00000452448.2
ENST00000494014.1
EPH receptor A3
chr16_+_2205755 0.10 ENST00000326181.6
TNF receptor-associated factor 7, E3 ubiquitin protein ligase
chr1_-_45956822 0.10 ENST00000372086.3
ENST00000341771.6
testis-specific kinase 2
chr15_+_66994561 0.09 ENST00000288840.5
SMAD family member 6
chr8_+_35649365 0.09 ENST00000437887.1
Uncharacterized protein
chr17_-_39538550 0.09 ENST00000394001.1
keratin 34
chr1_+_84630574 0.08 ENST00000413538.1
ENST00000417530.1
protein kinase, cAMP-dependent, catalytic, beta
chr7_+_16700806 0.08 ENST00000446596.1
ENST00000438834.1
basic leucine zipper and W2 domains 2
chr22_-_38240316 0.08 ENST00000411961.2
ENST00000434930.1
ankyrin repeat domain 54
chr1_-_45956800 0.08 ENST00000538496.1
testis-specific kinase 2
chr10_+_104005272 0.07 ENST00000369983.3
golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr1_+_84630352 0.07 ENST00000450730.1
protein kinase, cAMP-dependent, catalytic, beta
chr12_-_94673956 0.07 ENST00000551941.1
Uncharacterized protein
chr8_+_77593448 0.07 ENST00000521891.2
zinc finger homeobox 4
chr2_+_173724771 0.07 ENST00000538974.1
ENST00000540783.1
Rap guanine nucleotide exchange factor (GEF) 4
chr9_-_130829588 0.06 ENST00000373078.4
nuclear apoptosis inducing factor 1
chr6_-_116833500 0.06 ENST00000356128.4
trafficking protein particle complex 3-like
chr6_-_43021612 0.06 ENST00000535468.1
cullin 7
chr1_-_12679171 0.06 ENST00000606790.1
RP11-474O21.5
chr8_+_119294456 0.06 ENST00000366457.2
Uncharacterized protein
chr18_-_52989217 0.05 ENST00000570287.2
transcription factor 4
chr7_-_11871815 0.05 ENST00000423059.4
thrombospondin, type I, domain containing 7A
chr7_+_128784712 0.05 ENST00000289407.4
tetraspanin 33
chr17_+_18086392 0.04 ENST00000541285.1
alkB, alkylation repair homolog 5 (E. coli)
chr1_+_23037323 0.04 ENST00000544305.1
ENST00000374630.3
ENST00000400191.3
ENST00000374632.3
EPH receptor B2
chr18_+_68002675 0.04 ENST00000584919.1
Uncharacterized protein
chr3_-_150690786 0.04 ENST00000327047.1
clarin 1
chr1_+_210501589 0.03 ENST00000413764.2
ENST00000541565.1
hedgehog acyltransferase
chr1_+_84629976 0.03 ENST00000446538.1
ENST00000370684.1
ENST00000436133.1
protein kinase, cAMP-dependent, catalytic, beta
chr1_-_54879140 0.03 ENST00000525990.1
single stranded DNA binding protein 3
chr9_+_103947311 0.02 ENST00000395056.2
Lipid phosphate phosphatase-related protein type 1
chr14_+_76776957 0.02 ENST00000512784.1
estrogen-related receptor beta
chr4_+_169575875 0.02 ENST00000503457.1
palladin, cytoskeletal associated protein
chr15_+_71839566 0.01 ENST00000357769.4
thrombospondin, type I, domain containing 4
chr9_+_125132803 0.01 ENST00000540753.1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr13_+_28813645 0.01 ENST00000282391.5
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr6_-_139613269 0.01 ENST00000358430.3
taxilin beta
chr5_-_159766528 0.01 ENST00000505287.2
cyclin J-like
chr9_+_22646189 0.01 ENST00000436786.1
RP11-399D6.2
chr1_+_52682052 0.01 ENST00000371591.1
zinc finger, FYVE domain containing 9
chr21_+_30673091 0.00 ENST00000447177.1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr8_-_114449112 0.00 ENST00000455883.2
ENST00000352409.3
ENST00000297405.5
CUB and Sushi multiple domains 3
chr14_-_68000442 0.00 ENST00000554278.1
transmembrane protein 229B
chr1_+_78769549 0.00 ENST00000370758.1
prostaglandin F receptor (FP)
chr21_+_30672433 0.00 ENST00000451655.1
BTB and CNC homology 1, basic leucine zipper transcription factor 1

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB13

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.2 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.2 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.1 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.0 0.1 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.0 0.3 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.0 0.1 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.0 1.0 GO:0000786 nucleosome(GO:0000786)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0070698 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity(GO:0030617) type I activin receptor binding(GO:0070698)
0.0 0.2 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.1 GO:0032810 sterol response element binding(GO:0032810)
0.0 0.3 GO:0035198 miRNA binding(GO:0035198)
0.0 0.2 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends