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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for HOXA1

Z-value: 1.06

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Transcription factors associated with HOXA1

Gene Symbol Gene ID Gene Info
HOXA1
ENSG00000105991.7 homeobox A1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXA1hg19_v2_chr7_-_27135591_27135658-0.703.0e-01Click!

Activity profile of HOXA1 motif

Sorted Z-values of HOXA1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_10697895 1.88 ENST00000591240.1
ENST00000589684.1
ENST00000591676.1
ENST00000250244.6
ENST00000590923.1
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr20_-_36794938 1.19 ENST00000453095.1
TGM2
transglutaminase 2
chr20_-_36794902 1.14 ENST00000373403.3
TGM2
transglutaminase 2
chr22_+_41968007 0.73 ENST00000460790.1
CSDC2
cold shock domain containing C2, RNA binding
chr16_+_28985542 0.67 ENST00000567771.1
ENST00000568388.1
SPNS1
spinster homolog 1 (Drosophila)
chr10_-_81932771 0.62 ENST00000437799.1
ANXA11
annexin A11
chr16_+_28986085 0.59 ENST00000565975.1
ENST00000311008.11
ENST00000323081.8
ENST00000334536.8
SPNS1
spinster homolog 1 (Drosophila)
chr8_+_37887772 0.57 ENST00000338825.4
EIF4EBP1
eukaryotic translation initiation factor 4E binding protein 1
chr5_-_139930713 0.57 ENST00000602657.1
SRA1
steroid receptor RNA activator 1
chr20_-_23618582 0.52 ENST00000398411.1
ENST00000376925.3
CST3
cystatin C
chr1_-_149812765 0.50 ENST00000369158.1
HIST2H3C
histone cluster 2, H3c
chr16_+_21623958 0.48 ENST00000568826.1
METTL9
methyltransferase like 9
chr3_-_9834463 0.48 ENST00000439043.1
TADA3
transcriptional adaptor 3
chr17_-_8027402 0.47 ENST00000541682.2
ENST00000317814.4
ENST00000577735.1
HES7
hes family bHLH transcription factor 7
chr7_-_3214287 0.46 ENST00000404626.3
AC091801.1
LOC392621; Uncharacterized protein
chr19_+_16435625 0.45 ENST00000248071.5
ENST00000592003.1
KLF2
Kruppel-like factor 2
chr16_+_28986134 0.44 ENST00000352260.7
SPNS1
spinster homolog 1 (Drosophila)
chr3_-_129375556 0.44 ENST00000510323.1
TMCC1
transmembrane and coiled-coil domain family 1
chr11_+_118754475 0.43 ENST00000292174.4
CXCR5
chemokine (C-X-C motif) receptor 5
chr16_+_31213206 0.43 ENST00000561916.2
C16orf98
chromosome 16 open reading frame 98
chr1_-_45140074 0.43 ENST00000420706.1
ENST00000372235.3
ENST00000372242.3
ENST00000372243.3
ENST00000372244.3
TMEM53
transmembrane protein 53
chr16_+_28303804 0.40 ENST00000341901.4
SBK1
SH3 domain binding kinase 1
chr2_-_239148599 0.39 ENST00000409182.1
ENST00000409002.3
ENST00000450098.1
ENST00000409356.1
ENST00000409160.3
ENST00000409574.1
ENST00000272937.5
HES6
hes family bHLH transcription factor 6
chr22_+_25615489 0.36 ENST00000398215.2
CRYBB2
crystallin, beta B2
chr17_+_43239191 0.36 ENST00000589230.1
HEXIM2
hexamethylene bis-acetamide inducible 2
chr12_+_123459127 0.36 ENST00000397389.2
ENST00000538755.1
ENST00000536150.1
ENST00000545056.1
ENST00000545612.1
ENST00000538628.1
ENST00000545317.1
OGFOD2
2-oxoglutarate and iron-dependent oxygenase domain containing 2
chr3_+_112929850 0.35 ENST00000464546.1
BOC
BOC cell adhesion associated, oncogene regulated
chr7_+_100136811 0.34 ENST00000300176.4
ENST00000262935.4
AGFG2
ArfGAP with FG repeats 2
chr12_+_78359999 0.33 ENST00000550503.1
NAV3
neuron navigator 3
chr15_-_74501360 0.33 ENST00000323940.5
STRA6
stimulated by retinoic acid 6
chr14_+_24779340 0.32 ENST00000533293.1
ENST00000543919.1
LTB4R2
leukotriene B4 receptor 2
chr11_+_114166536 0.32 ENST00000299964.3
NNMT
nicotinamide N-methyltransferase
chr9_-_130679257 0.32 ENST00000361444.3
ENST00000335791.5
ENST00000343609.2
ST6GALNAC4
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr17_-_8059638 0.32 ENST00000584202.1
ENST00000354903.5
ENST00000577253.1
PER1
period circadian clock 1
chr6_+_43395272 0.32 ENST00000372530.4
ABCC10
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
chr10_-_79397547 0.31 ENST00000481070.1
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr10_-_75012360 0.30 ENST00000416782.2
ENST00000372945.3
ENST00000372940.3
MRPS16
mitochondrial ribosomal protein S16
chr11_-_126870655 0.30 ENST00000525144.2
KIRREL3
kin of IRRE like 3 (Drosophila)
chr7_-_559853 0.29 ENST00000405692.2
PDGFA
platelet-derived growth factor alpha polypeptide
chr14_-_23504337 0.29 ENST00000361611.6
PSMB5
proteasome (prosome, macropain) subunit, beta type, 5
chr5_+_133861790 0.29 ENST00000395003.1
PHF15
jade family PHD finger 2
chr8_+_22250334 0.27 ENST00000520832.1
SLC39A14
solute carrier family 39 (zinc transporter), member 14
chr5_-_180237082 0.26 ENST00000506889.1
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr19_-_5680891 0.26 ENST00000309324.4
C19orf70
chromosome 19 open reading frame 70
chr2_+_65215604 0.25 ENST00000531327.1
SLC1A4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr9_-_128246769 0.25 ENST00000444226.1
MAPKAP1
mitogen-activated protein kinase associated protein 1
chr7_-_994302 0.25 ENST00000265846.5
ADAP1
ArfGAP with dual PH domains 1
chrX_-_57937067 0.25 ENST00000358697.4
ZXDA
zinc finger, X-linked, duplicated A
chr18_+_3411595 0.25 ENST00000552383.1
TGIF1
TGFB-induced factor homeobox 1
chr14_-_23822061 0.25 ENST00000397260.3
SLC22A17
solute carrier family 22, member 17
chr11_-_126870683 0.24 ENST00000525704.2
KIRREL3
kin of IRRE like 3 (Drosophila)
chr3_-_49967292 0.24 ENST00000455683.2
MON1A
MON1 secretory trafficking family member A
chr3_-_150264272 0.24 ENST00000491660.1
ENST00000487153.1
ENST00000239944.2
SERP1
stress-associated endoplasmic reticulum protein 1
chr5_-_125930877 0.23 ENST00000510111.2
ENST00000509270.1
ALDH7A1
aldehyde dehydrogenase 7 family, member A1
chr2_+_74685413 0.23 ENST00000233615.2
WBP1
WW domain binding protein 1
chr22_-_22307199 0.23 ENST00000397495.4
ENST00000263212.5
PPM1F
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr3_+_9834227 0.22 ENST00000287613.7
ENST00000397261.3
ARPC4
actin related protein 2/3 complex, subunit 4, 20kDa
chr15_-_60695071 0.22 ENST00000557904.1
ANXA2
annexin A2
chr2_-_190044480 0.22 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr15_-_64673665 0.22 ENST00000300035.4
KIAA0101
KIAA0101
chr15_-_64673630 0.22 ENST00000558008.1
ENST00000559519.1
ENST00000380258.2
KIAA0101
KIAA0101
chr16_+_71660079 0.22 ENST00000565261.1
ENST00000268485.3
ENST00000299952.4
MARVELD3
MARVEL domain containing 3
chr14_+_91709103 0.22 ENST00000553725.1
CTD-2547L24.3
HCG1816139; Uncharacterized protein
chrX_-_25034065 0.22 ENST00000379044.4
ARX
aristaless related homeobox
chr16_-_66584015 0.21 ENST00000545043.2
TK2
thymidine kinase 2, mitochondrial
chr2_+_27255806 0.21 ENST00000238788.9
ENST00000404032.3
TMEM214
transmembrane protein 214
chr8_+_104152922 0.21 ENST00000309982.5
ENST00000438105.2
ENST00000297574.6
BAALC
brain and acute leukemia, cytoplasmic
chr9_+_132962843 0.21 ENST00000458469.1
NCS1
neuronal calcium sensor 1
chr17_+_43239231 0.21 ENST00000591576.1
ENST00000591070.1
ENST00000592695.1
HEXIM2
hexamethylene bis-acetamide inducible 2
chr11_-_111649074 0.20 ENST00000534218.1
RP11-108O10.2
RP11-108O10.2
chr6_+_42123141 0.20 ENST00000418175.1
ENST00000541991.1
ENST00000053469.4
ENST00000394237.1
ENST00000372963.1
GUCA1A
RP1-139D8.6
guanylate cyclase activator 1A (retina)
RP1-139D8.6
chr19_+_13875316 0.20 ENST00000319545.8
ENST00000593245.1
ENST00000040663.6
MRI1
methylthioribose-1-phosphate isomerase 1
chrX_-_1331527 0.20 ENST00000381567.3
ENST00000381566.1
ENST00000400841.2
CRLF2
cytokine receptor-like factor 2
chr1_+_154975110 0.20 ENST00000535420.1
ENST00000368426.3
ZBTB7B
zinc finger and BTB domain containing 7B
chr17_-_40835076 0.20 ENST00000591765.1
CCR10
chemokine (C-C motif) receptor 10
chr2_+_87808725 0.20 ENST00000413202.1
LINC00152
long intergenic non-protein coding RNA 152
chr14_-_23504432 0.20 ENST00000425762.2
PSMB5
proteasome (prosome, macropain) subunit, beta type, 5
chr19_-_39368887 0.20 ENST00000340740.3
ENST00000591812.1
RINL
Ras and Rab interactor-like
chr1_-_201096312 0.20 ENST00000449188.2
ASCL5
achaete-scute family bHLH transcription factor 5
chr17_-_15501932 0.20 ENST00000583965.1
CDRT1
CMT1A duplicated region transcript 1
chr2_-_112237835 0.19 ENST00000442293.1
ENST00000439494.1
MIR4435-1HG
MIR4435-1 host gene (non-protein coding)
chr13_+_28519343 0.19 ENST00000381026.3
ATP5EP2
ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit pseudogene 2
chr7_+_74379083 0.19 ENST00000361825.7
GATSL1
GATS protein-like 1
chr19_+_1026298 0.18 ENST00000263097.4
CNN2
calponin 2
chr5_+_150040403 0.18 ENST00000517768.1
ENST00000297130.4
MYOZ3
myozenin 3
chr1_+_145209092 0.18 ENST00000362074.6
ENST00000344859.3
NOTCH2NL
notch 2 N-terminal like
chr19_-_15544099 0.18 ENST00000599910.2
WIZ
widely interspaced zinc finger motifs
chr19_-_11450249 0.18 ENST00000222120.3
RAB3D
RAB3D, member RAS oncogene family
chr19_+_54371114 0.18 ENST00000448420.1
ENST00000439000.1
ENST00000391770.4
ENST00000391771.1
MYADM
myeloid-associated differentiation marker
chr12_-_49449107 0.18 ENST00000301067.7
KMT2D
lysine (K)-specific methyltransferase 2D
chr17_-_39041479 0.17 ENST00000167588.3
KRT20
keratin 20
chr19_+_10654854 0.17 ENST00000586477.1
ENST00000586863.1
ATG4D
autophagy related 4D, cysteine peptidase
chr18_+_18943554 0.17 ENST00000580732.2
GREB1L
growth regulation by estrogen in breast cancer-like
chr2_+_74685527 0.17 ENST00000393972.3
ENST00000409737.1
ENST00000428943.1
WBP1
WW domain binding protein 1
chr19_+_5681153 0.17 ENST00000579559.1
ENST00000577222.1
HSD11B1L
RPL36
hydroxysteroid (11-beta) dehydrogenase 1-like
ribosomal protein L36
chrX_+_48455866 0.16 ENST00000376729.5
ENST00000218056.5
WDR13
WD repeat domain 13
chr17_+_60447579 0.16 ENST00000450662.2
EFCAB3
EF-hand calcium binding domain 3
chr12_+_57998400 0.16 ENST00000548804.1
ENST00000550596.1
ENST00000551835.1
ENST00000549583.1
DTX3
deltex homolog 3 (Drosophila)
chr9_-_116861337 0.16 ENST00000374118.3
KIF12
kinesin family member 12
chr18_-_74207146 0.16 ENST00000443185.2
ZNF516
zinc finger protein 516
chr8_-_119124045 0.15 ENST00000378204.2
EXT1
exostosin glycosyltransferase 1
chr11_+_61248583 0.15 ENST00000432063.2
ENST00000338608.2
PPP1R32
protein phosphatase 1, regulatory subunit 32
chr20_-_3154162 0.14 ENST00000360342.3
LZTS3
Homo sapiens leucine zipper, putative tumor suppressor family member 3 (LZTS3), mRNA.
chr1_-_157014865 0.14 ENST00000361409.2
ARHGEF11
Rho guanine nucleotide exchange factor (GEF) 11
chr12_-_85306594 0.14 ENST00000266682.5
SLC6A15
solute carrier family 6 (neutral amino acid transporter), member 15
chr22_-_39190116 0.14 ENST00000406622.1
ENST00000216068.4
ENST00000406199.3
SUN2
DNAL4
Sad1 and UNC84 domain containing 2
dynein, axonemal, light chain 4
chr20_+_36012051 0.14 ENST00000373567.2
SRC
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr12_-_121342170 0.14 ENST00000353487.2
SPPL3
signal peptide peptidase like 3
chr14_+_24779376 0.14 ENST00000530080.1
LTB4R2
leukotriene B4 receptor 2
chr5_-_151138200 0.14 ENST00000313115.6
ENST00000522710.1
ATOX1
antioxidant 1 copper chaperone
chr15_-_74501310 0.13 ENST00000423167.2
ENST00000432245.2
STRA6
stimulated by retinoic acid 6
chr7_+_139528952 0.13 ENST00000416849.2
ENST00000436047.2
ENST00000414508.2
ENST00000448866.1
TBXAS1
thromboxane A synthase 1 (platelet)
chrX_+_54834791 0.13 ENST00000218439.4
ENST00000375058.1
ENST00000375060.1
MAGED2
melanoma antigen family D, 2
chr10_-_33623310 0.13 ENST00000395995.1
ENST00000374823.5
ENST00000374821.5
ENST00000374816.3
NRP1
neuropilin 1
chr2_-_75788038 0.13 ENST00000393913.3
ENST00000410113.1
EVA1A
eva-1 homolog A (C. elegans)
chr12_+_48577366 0.13 ENST00000316554.3
C12orf68
chromosome 12 open reading frame 68
chr22_+_29834572 0.13 ENST00000354373.2
RFPL1
ret finger protein-like 1
chr16_-_88752889 0.13 ENST00000332281.5
SNAI3
snail family zinc finger 3
chr2_-_70189397 0.12 ENST00000320256.4
ASPRV1
aspartic peptidase, retroviral-like 1
chr17_+_39975544 0.12 ENST00000544340.1
FKBP10
FK506 binding protein 10, 65 kDa
chrX_-_52258669 0.12 ENST00000441417.1
XAGE1A
X antigen family, member 1A
chr10_+_90562487 0.12 ENST00000404743.4
LIPM
lipase, family member M
chr2_+_161993465 0.12 ENST00000457476.1
TANK
TRAF family member-associated NFKB activator
chr12_+_125478241 0.12 ENST00000341446.8
BRI3BP
BRI3 binding protein
chr3_+_127872265 0.12 ENST00000254730.6
ENST00000483457.1
EEFSEC
eukaryotic elongation factor, selenocysteine-tRNA-specific
chr6_-_44233361 0.11 ENST00000275015.5
NFKBIE
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr1_+_205473720 0.11 ENST00000429964.2
ENST00000506784.1
ENST00000360066.2
CDK18
cyclin-dependent kinase 18
chr7_+_139529040 0.11 ENST00000455353.1
ENST00000458722.1
ENST00000411653.1
TBXAS1
thromboxane A synthase 1 (platelet)
chr10_-_28270795 0.11 ENST00000545014.1
ARMC4
armadillo repeat containing 4
chr20_-_30458491 0.11 ENST00000339738.5
DUSP15
dual specificity phosphatase 15
chr10_-_101380121 0.11 ENST00000370495.4
SLC25A28
solute carrier family 25 (mitochondrial iron transporter), member 28
chr12_+_58148842 0.10 ENST00000266643.5
MARCH9
membrane-associated ring finger (C3HC4) 9
chr17_+_39975455 0.10 ENST00000455106.1
FKBP10
FK506 binding protein 10, 65 kDa
chr4_+_113970772 0.10 ENST00000504454.1
ENST00000394537.3
ENST00000357077.4
ENST00000264366.6
ANK2
ankyrin 2, neuronal
chr5_+_36152091 0.10 ENST00000274254.5
SKP2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr3_+_38537960 0.10 ENST00000453767.1
EXOG
endo/exonuclease (5'-3'), endonuclease G-like
chr8_-_66546373 0.10 ENST00000518908.1
ENST00000458464.2
ENST00000519352.1
ARMC1
armadillo repeat containing 1
chr10_+_98741041 0.09 ENST00000286067.2
C10orf12
chromosome 10 open reading frame 12
chr11_-_2162162 0.09 ENST00000381389.1
IGF2
insulin-like growth factor 2 (somatomedin A)
chr15_-_75134992 0.09 ENST00000568667.1
ULK3
unc-51 like kinase 3
chr7_+_30174574 0.09 ENST00000409688.1
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr19_-_45735138 0.09 ENST00000252482.3
EXOC3L2
exocyst complex component 3-like 2
chr15_+_67418047 0.09 ENST00000540846.2
SMAD3
SMAD family member 3
chr16_-_28303360 0.09 ENST00000501520.1
RP11-57A19.2
RP11-57A19.2
chr11_+_66247478 0.09 ENST00000531863.1
ENST00000532677.1
DPP3
dipeptidyl-peptidase 3
chr11_+_63706444 0.09 ENST00000377793.4
ENST00000456907.2
ENST00000539656.1
NAA40
N(alpha)-acetyltransferase 40, NatD catalytic subunit
chr11_+_122733011 0.09 ENST00000533709.1
CRTAM
cytotoxic and regulatory T cell molecule
chr19_-_33360647 0.09 ENST00000590341.1
ENST00000587772.1
ENST00000023064.4
SLC7A9
solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
chr1_+_154975258 0.09 ENST00000417934.2
ZBTB7B
zinc finger and BTB domain containing 7B
chr10_+_90562705 0.09 ENST00000539337.1
LIPM
lipase, family member M
chr11_-_61647935 0.09 ENST00000531956.1
FADS3
fatty acid desaturase 3
chr22_-_30866564 0.09 ENST00000435069.1
ENST00000415957.2
ENST00000540910.1
SEC14L3
SEC14-like 3 (S. cerevisiae)
chr20_-_62168714 0.09 ENST00000542869.1
PTK6
protein tyrosine kinase 6
chr17_-_44896047 0.08 ENST00000225512.5
WNT3
wingless-type MMTV integration site family, member 3
chr13_-_23490508 0.08 ENST00000577004.1
LINC00621
long intergenic non-protein coding RNA 621
chr3_+_14444063 0.08 ENST00000454876.2
ENST00000360861.3
ENST00000416216.2
SLC6A6
solute carrier family 6 (neurotransmitter transporter), member 6
chr7_+_97736197 0.08 ENST00000297293.5
LMTK2
lemur tyrosine kinase 2
chr17_+_4046964 0.08 ENST00000573984.1
CYB5D2
cytochrome b5 domain containing 2
chr17_+_39994032 0.08 ENST00000293303.4
ENST00000438813.1
KLHL10
kelch-like family member 10
chr3_+_9834179 0.08 ENST00000498623.2
ARPC4
actin related protein 2/3 complex, subunit 4, 20kDa
chr13_-_36050819 0.08 ENST00000379919.4
MAB21L1
mab-21-like 1 (C. elegans)
chrM_+_4431 0.08 ENST00000361453.3
MT-ND2
mitochondrially encoded NADH dehydrogenase 2
chr20_+_44036900 0.07 ENST00000443296.1
DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr3_+_49059038 0.07 ENST00000451378.2
NDUFAF3
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr7_+_20370746 0.07 ENST00000222573.4
ITGB8
integrin, beta 8
chr7_-_99332719 0.07 ENST00000336374.2
CYP3A7
cytochrome P450, family 3, subfamily A, polypeptide 7
chr16_+_57680840 0.07 ENST00000563862.1
ENST00000564722.1
ENST00000569158.1
GPR56
G protein-coupled receptor 56
chr12_-_23737534 0.07 ENST00000396007.2
SOX5
SRY (sex determining region Y)-box 5
chr12_+_10658489 0.07 ENST00000538173.1
EIF2S3L
Putative eukaryotic translation initiation factor 2 subunit 3-like protein
chr11_-_111649015 0.07 ENST00000529841.1
RP11-108O10.2
RP11-108O10.2
chr9_-_101471479 0.07 ENST00000259455.2
GABBR2
gamma-aminobutyric acid (GABA) B receptor, 2
chr12_+_57610562 0.07 ENST00000349394.5
NXPH4
neurexophilin 4
chr16_-_55867146 0.07 ENST00000422046.2
CES1
carboxylesterase 1
chr14_+_65453432 0.07 ENST00000246166.2
FNTB
farnesyltransferase, CAAX box, beta
chr10_+_89264625 0.07 ENST00000371996.4
ENST00000371994.4
MINPP1
multiple inositol-polyphosphate phosphatase 1
chrX_+_57618269 0.06 ENST00000374888.1
ZXDB
zinc finger, X-linked, duplicated B
chrX_+_37639302 0.06 ENST00000545017.1
ENST00000536160.1
CYBB
cytochrome b-245, beta polypeptide
chr1_-_207095212 0.06 ENST00000420007.2
FAIM3
Fas apoptotic inhibitory molecule 3
chr7_-_137028534 0.06 ENST00000348225.2
PTN
pleiotrophin
chr13_+_30002741 0.06 ENST00000380808.2
MTUS2
microtubule associated tumor suppressor candidate 2
chr16_+_21608525 0.06 ENST00000567404.1
METTL9
methyltransferase like 9
chr1_+_367640 0.06 ENST00000426406.1
OR4F29
olfactory receptor, family 4, subfamily F, member 29
chr5_+_125758865 0.06 ENST00000542322.1
ENST00000544396.1
GRAMD3
GRAM domain containing 3
chr5_+_177433406 0.06 ENST00000504530.1
FAM153C
family with sequence similarity 153, member C
chr16_+_57680811 0.06 ENST00000569101.1
GPR56
G protein-coupled receptor 56
chr13_+_102104980 0.06 ENST00000545560.2
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr20_+_44036620 0.06 ENST00000372710.3
DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr5_+_133861339 0.06 ENST00000282605.4
ENST00000361895.2
ENST00000402835.1
PHF15
jade family PHD finger 2
chr2_+_166326157 0.06 ENST00000421875.1
ENST00000314499.7
ENST00000409664.1
CSRNP3
cysteine-serine-rich nuclear protein 3
chr9_+_35829208 0.06 ENST00000439587.2
ENST00000377991.4
TMEM8B
transmembrane protein 8B
chr8_+_1993152 0.06 ENST00000262113.4
MYOM2
myomesin 2
chr9_+_33795533 0.05 ENST00000379405.3
PRSS3
protease, serine, 3
chr1_-_151319654 0.05 ENST00000430227.1
ENST00000412774.1
RFX5
regulatory factor X, 5 (influences HLA class II expression)
chr11_+_3666335 0.05 ENST00000250693.1
ART1
ADP-ribosyltransferase 1
chr22_+_39101728 0.05 ENST00000216044.5
ENST00000484657.1
GTPBP1
GTP binding protein 1
chrX_-_148586804 0.05 ENST00000428056.2
ENST00000340855.6
ENST00000370441.4
ENST00000370443.4
IDS
iduronate 2-sulfatase
chr13_+_36050881 0.05 ENST00000537702.1
NBEA
neurobeachin
chr4_-_38806404 0.05 ENST00000308979.2
ENST00000505940.1
ENST00000515861.1
TLR1
toll-like receptor 1
chr7_-_137028498 0.05 ENST00000393083.2
PTN
pleiotrophin
chr9_+_113431059 0.05 ENST00000416899.2
MUSK
muscle, skeletal, receptor tyrosine kinase

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.3 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.2 0.5 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.1 0.5 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.1 0.5 GO:0051541 negative regulation of extracellular matrix disassembly(GO:0010716) elastin metabolic process(GO:0051541)
0.1 0.4 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.1 1.7 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.1 0.5 GO:0061143 alveolar primary septum development(GO:0061143)
0.1 0.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.3 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1 0.2 GO:0044147 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.1 0.2 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.1 0.5 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.2 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0 0.3 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.0 0.5 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.4 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.1 GO:0015680 intracellular copper ion transport(GO:0015680)
0.0 0.2 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.0 0.3 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0 0.1 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.0 0.2 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.3 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.2 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.1 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.0 0.1 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.0 0.2 GO:0001555 oocyte growth(GO:0001555)
0.0 0.3 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.3 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.1 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.1 GO:1902378 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) endothelial tip cell fate specification(GO:0097102) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.0 1.9 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.4 GO:0048535 lymph node development(GO:0048535)
0.0 0.1 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.0 0.2 GO:0051697 protein delipidation(GO:0051697)
0.0 0.1 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.3 GO:0034465 response to carbon monoxide(GO:0034465)
0.0 0.2 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:0048808 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0 0.6 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.2 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0 0.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0042495 detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.0 0.1 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339) canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
0.0 0.1 GO:0042940 D-amino acid transport(GO:0042940)
0.0 0.3 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.3 GO:0015684 ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
0.0 0.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.6 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736)
0.0 0.1 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.2 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.2 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.2 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.1 GO:0019049 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834) negative regulation of lung blood pressure(GO:0061767)
0.0 0.1 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.0 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
0.0 0.2 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.0 GO:0060178 regulation of exocyst assembly(GO:0001928) regulation of exocyst localization(GO:0060178)
0.0 0.0 GO:1904647 response to rotenone(GO:1904647)
0.0 0.1 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.3 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.1 GO:0002933 lipid hydroxylation(GO:0002933)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.2 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.5 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 1.9 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.2 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.5 GO:0030914 STAGA complex(GO:0030914)
0.0 0.1 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 0.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.1 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.1 GO:0097443 sorting endosome(GO:0097443)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.3 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.8 GO:1904724 tertiary granule lumen(GO:1904724)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.2 2.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.5 GO:0004974 leukotriene B4 receptor activity(GO:0001632) leukotriene receptor activity(GO:0004974)
0.1 0.3 GO:0030760 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.1 0.3 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.1 0.2 GO:0031433 telethonin binding(GO:0031433)
0.1 0.2 GO:0070984 SET domain binding(GO:0070984)
0.0 0.4 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.6 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.4 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.2 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.6 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.2 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0 0.3 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.1 GO:0032767 copper-dependent protein binding(GO:0032767)
0.0 0.1 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.3 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.1 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.0 0.1 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.6 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.2 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.3 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.3 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.0 0.3 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.0 0.1 GO:0004423 iduronate-2-sulfatase activity(GO:0004423)
0.0 0.1 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.5 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.0 0.1 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.1 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.0 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.5 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.2 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.5 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.5 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.6 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.5 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 1.0 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.3 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.1 REACTOME DEFENSINS Genes involved in Defensins