Project
A549 cells infected with IAV Analysis Results (GEO series: GSE147507)
Navigation
Downloads
Results for HOMEZ
Z-value: 1.06
Motif logo
Transcription factors associated with HOMEZ
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| HOMEZ | hg19_v2_chr14_-_23762777_23762821 | 0.26 | 7.4e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr18_+_44526744 Show fit | 0.50 |
ENST00000585469.1
|
katanin p60 subunit A-like 2 |
|
| chr11_+_102217936 Show fit | 0.49 |
ENST00000532832.1
ENST00000530675.1 ENST00000533742.1 ENST00000227758.2 ENST00000532672.1 ENST00000531259.1 ENST00000527465.1 |
baculoviral IAP repeat containing 2 |
|
| chr15_+_63414760 Show fit | 0.45 |
ENST00000557972.1
|
lactamase, beta |
|
| chrX_-_119709637 Show fit | 0.41 |
ENST00000404115.3
|
cullin 4B |
|
| chr6_+_80714332 Show fit | 0.39 |
ENST00000502580.1
ENST00000511260.1 |
TTK protein kinase |
|
| chr8_-_56986768 Show fit | 0.39 |
ENST00000523936.1
|
ribosomal protein S20 |
|
| chr8_-_54934708 Show fit | 0.38 |
ENST00000520534.1
ENST00000518784.1 ENST00000522635.1 |
transcription elongation factor A (SII), 1 |
|
| chr11_-_32816156 Show fit | 0.35 |
ENST00000531481.1
ENST00000335185.5 |
coiled-coil domain containing 73 |
|
| chr21_+_17443521 Show fit | 0.34 |
ENST00000456342.1
|
long intergenic non-protein coding RNA 478 |
|
| chrX_+_21959108 Show fit | 0.34 |
ENST00000457085.1
|
spermine synthase |
Network of associatons between targets according to the STRING database.
First level regulatory network of HOMEZ
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.1 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 0.2 | 0.6 | GO:0048213 | Golgi vesicle prefusion complex stabilization(GO:0048213) |
| 0.2 | 0.5 | GO:1902523 | positive regulation of protein K63-linked ubiquitination(GO:1902523) |
| 0.0 | 0.5 | GO:0071539 | protein localization to centrosome(GO:0071539) |
| 0.1 | 0.4 | GO:1901994 | meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) |
| 0.1 | 0.4 | GO:0051083 | 'de novo' cotranslational protein folding(GO:0051083) |
| 0.1 | 0.4 | GO:0007079 | mitotic chromosome movement towards spindle pole(GO:0007079) |
| 0.0 | 0.4 | GO:2001168 | regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168) |
| 0.0 | 0.4 | GO:0070914 | UV-damage excision repair(GO:0070914) |
| 0.0 | 0.4 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.6 | GO:0033503 | HULC complex(GO:0033503) |
| 0.0 | 0.6 | GO:0001741 | XY body(GO:0001741) |
| 0.0 | 0.6 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 0.0 | 0.5 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 0.0 | 0.4 | GO:0000836 | Hrd1p ubiquitin ligase complex(GO:0000836) |
| 0.0 | 0.4 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 0.0 | 0.4 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 0.1 | 0.3 | GO:0034388 | Pwp2p-containing subcomplex of 90S preribosome(GO:0034388) |
| 0.0 | 0.3 | GO:0043564 | Ku70:Ku80 complex(GO:0043564) |
| 0.0 | 0.3 | GO:0030891 | VCB complex(GO:0030891) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.1 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 0.1 | 0.7 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 0.0 | 0.7 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.1 | 0.6 | GO:0043515 | kinetochore binding(GO:0043515) |
| 0.2 | 0.5 | GO:0098770 | FBXO family protein binding(GO:0098770) |
| 0.0 | 0.5 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 0.1 | 0.4 | GO:0004906 | interferon-gamma receptor activity(GO:0004906) |
| 0.1 | 0.4 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
| 0.1 | 0.4 | GO:0044547 | DNA topoisomerase binding(GO:0044547) |
| 0.0 | 0.4 | GO:0051787 | misfolded protein binding(GO:0051787) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.3 | PID NFKAPPAB CANONICAL PATHWAY | Canonical NF-kappaB pathway |
| 0.0 | 0.6 | PID BARD1 PATHWAY | BARD1 signaling events |
| 0.0 | 0.4 | ST INTERFERON GAMMA PATHWAY | Interferon gamma pathway. |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.9 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 0.0 | 0.9 | REACTOME ELONGATION ARREST AND RECOVERY | Genes involved in Elongation arrest and recovery |
| 0.0 | 0.8 | REACTOME NOD1 2 SIGNALING PATHWAY | Genes involved in NOD1/2 Signaling Pathway |
| 0.0 | 0.5 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.0 | 0.4 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.0 | 0.4 | REACTOME REGULATION OF IFNG SIGNALING | Genes involved in Regulation of IFNG signaling |
| 0.0 | 0.4 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.0 | 0.3 | REACTOME POL SWITCHING | Genes involved in Polymerase switching |
| 0.0 | 0.3 | REACTOME INTEGRATION OF PROVIRUS | Genes involved in Integration of provirus |
| 0.0 | 0.3 | REACTOME CALNEXIN CALRETICULIN CYCLE | Genes involved in Calnexin/calreticulin cycle |