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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for HMGA2

Z-value: 0.28

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Transcription factors associated with HMGA2

Gene Symbol Gene ID Gene Info
HMGA2
ENSG00000149948.9 high mobility group AT-hook 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HMGA2hg19_v2_chr12_+_66218212_66218244-0.955.1e-02Click!

Activity profile of HMGA2 motif

Sorted Z-values of HMGA2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_65996599 0.11 ENST00000539116.1
ENST00000541391.1
RP11-221N13.3
RP11-221N13.3
chr2_-_151395525 0.09 ENST00000439275.1
RND3
Rho family GTPase 3
chr10_-_36813162 0.08 ENST00000440465.1
NAMPTL
nicotinamide phosphoribosyltransferase-like
chr15_+_30375158 0.08 ENST00000341650.6
ENST00000567927.1
GOLGA8J
golgin A8 family, member J
chr9_-_115480303 0.07 ENST00000374234.1
ENST00000374238.1
ENST00000374236.1
ENST00000374242.4
INIP
INTS3 and NABP interacting protein
chrX_-_128782722 0.07 ENST00000427399.1
APLN
apelin
chr12_-_8765446 0.07 ENST00000537228.1
ENST00000229335.6
AICDA
activation-induced cytidine deaminase
chr1_+_227751231 0.06 ENST00000343776.5
ENST00000608949.1
ENST00000397097.3
ZNF678
zinc finger protein 678
chr1_-_43638168 0.06 ENST00000431635.2
EBNA1BP2
EBNA1 binding protein 2
chr2_-_114461655 0.06 ENST00000424612.1
AC017074.2
AC017074.2
chr4_+_40058411 0.06 ENST00000261435.6
ENST00000515550.1
N4BP2
NEDD4 binding protein 2
chr10_-_101673782 0.06 ENST00000422692.1
DNMBP
dynamin binding protein
chr15_+_43885252 0.05 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
CKMT1B
creatine kinase, mitochondrial 1B
chr19_+_44455368 0.05 ENST00000591168.1
ENST00000587682.1
ENST00000251269.5
ZNF221
zinc finger protein 221
chr10_+_35456444 0.05 ENST00000361599.4
CREM
cAMP responsive element modulator
chr17_+_73230799 0.05 ENST00000579838.1
NUP85
nucleoporin 85kDa
chr7_-_102985035 0.05 ENST00000426036.2
ENST00000249270.7
ENST00000454277.1
ENST00000412522.1
DNAJC2
DnaJ (Hsp40) homolog, subfamily C, member 2
chr14_-_94759595 0.04 ENST00000261994.4
SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr12_-_21757774 0.04 ENST00000261195.2
GYS2
glycogen synthase 2 (liver)
chr12_+_69979113 0.04 ENST00000299300.6
CCT2
chaperonin containing TCP1, subunit 2 (beta)
chrX_+_2670066 0.04 ENST00000381174.5
ENST00000419513.2
ENST00000426774.1
XG
Xg blood group
chr1_-_67600639 0.04 ENST00000544837.1
ENST00000603691.1
C1orf141
chromosome 1 open reading frame 141
chr5_-_102455801 0.04 ENST00000508629.1
ENST00000399004.2
GIN1
gypsy retrotransposon integrase 1
chr9_+_108463234 0.04 ENST00000374688.1
TMEM38B
transmembrane protein 38B
chrX_-_7895479 0.04 ENST00000381042.4
PNPLA4
patatin-like phospholipase domain containing 4
chr1_-_226374373 0.04 ENST00000366812.5
ACBD3
acyl-CoA binding domain containing 3
chr15_+_43985084 0.04 ENST00000434505.1
ENST00000411750.1
CKMT1A
creatine kinase, mitochondrial 1A
chr14_-_94759408 0.04 ENST00000554723.1
SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr12_-_122750957 0.04 ENST00000451053.2
VPS33A
vacuolar protein sorting 33 homolog A (S. cerevisiae)
chr14_-_94759361 0.04 ENST00000393096.1
SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr9_+_104296122 0.04 ENST00000389120.3
RNF20
ring finger protein 20, E3 ubiquitin protein ligase
chr11_+_65122216 0.04 ENST00000309880.5
TIGD3
tigger transposable element derived 3
chr20_+_54967663 0.04 ENST00000452950.1
CSTF1
cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
chr14_+_45553296 0.04 ENST00000355765.6
ENST00000553605.1
PRPF39
pre-mRNA processing factor 39
chr15_+_84904525 0.04 ENST00000510439.2
GOLGA6L4
golgin A6 family-like 4
chr6_-_127664683 0.04 ENST00000528402.1
ENST00000454591.2
ECHDC1
enoyl CoA hydratase domain containing 1
chr1_+_28836561 0.03 ENST00000419074.1
RCC1
regulator of chromosome condensation 1
chr17_-_48785216 0.03 ENST00000285243.6
ANKRD40
ankyrin repeat domain 40
chr15_-_83018198 0.03 ENST00000557886.1
RP13-996F3.4
golgin A6 family-like 19
chr3_-_123680246 0.03 ENST00000488653.2
CCDC14
coiled-coil domain containing 14
chr15_-_82939157 0.03 ENST00000559949.1
RP13-996F3.5
golgin A6 family-like 18
chr1_-_223988426 0.03 ENST00000391879.2
TP53BP2
tumor protein p53 binding protein, 2
chr4_+_25378912 0.03 ENST00000510092.1
ENST00000505991.1
ANAPC4
anaphase promoting complex subunit 4
chr6_+_116892641 0.03 ENST00000487832.2
ENST00000518117.1
RWDD1
RWD domain containing 1
chrX_+_117480036 0.03 ENST00000371822.5
ENST00000254029.3
ENST00000371825.3
WDR44
WD repeat domain 44
chr21_+_38792602 0.03 ENST00000398960.2
ENST00000398956.2
DYRK1A
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
chr15_+_82722225 0.03 ENST00000300515.8
GOLGA6L9
golgin A6 family-like 9
chr20_+_46130671 0.03 ENST00000371998.3
ENST00000371997.3
NCOA3
nuclear receptor coactivator 3
chr15_+_83098710 0.03 ENST00000561062.1
ENST00000358583.3
GOLGA6L9
golgin A6 family-like 20
chr15_+_28623784 0.03 ENST00000526619.2
ENST00000337838.7
ENST00000532622.2
GOLGA8F
golgin A8 family, member F
chr3_+_193853927 0.03 ENST00000232424.3
HES1
hes family bHLH transcription factor 1
chr12_+_69979210 0.03 ENST00000544368.2
CCT2
chaperonin containing TCP1, subunit 2 (beta)
chr19_-_11456872 0.02 ENST00000586218.1
TMEM205
transmembrane protein 205
chr12_-_10573149 0.02 ENST00000381904.2
ENST00000381903.2
ENST00000396439.2
KLRC3
killer cell lectin-like receptor subfamily C, member 3
chr7_-_102985288 0.02 ENST00000379263.3
DNAJC2
DnaJ (Hsp40) homolog, subfamily C, member 2
chr8_-_105479270 0.02 ENST00000521573.2
ENST00000351513.2
DPYS
dihydropyrimidinase
chrX_-_23926004 0.02 ENST00000379226.4
ENST00000379220.3
APOO
apolipoprotein O
chr20_+_46130619 0.02 ENST00000372004.3
NCOA3
nuclear receptor coactivator 3
chr6_-_136571400 0.02 ENST00000418509.2
ENST00000420702.1
ENST00000451457.2
MTFR2
mitochondrial fission regulator 2
chr1_+_197886461 0.02 ENST00000367388.3
ENST00000337020.2
ENST00000367387.4
LHX9
LIM homeobox 9
chr15_-_32747835 0.02 ENST00000509311.2
ENST00000414865.2
GOLGA8O
golgin A8 family, member O
chr2_+_172543967 0.02 ENST00000534253.2
ENST00000263811.4
ENST00000397119.3
ENST00000410079.3
ENST00000438879.1
DYNC1I2
dynein, cytoplasmic 1, intermediate chain 2
chr2_+_13677795 0.02 ENST00000434509.1
AC092635.1
AC092635.1
chr1_+_179263308 0.02 ENST00000426956.1
SOAT1
sterol O-acyltransferase 1
chr14_+_99947715 0.02 ENST00000389879.5
ENST00000557441.1
ENST00000555049.1
ENST00000555842.1
CCNK
cyclin K
chrX_-_135962876 0.02 ENST00000431446.3
ENST00000570135.1
ENST00000320676.7
ENST00000562646.1
RBMX
RNA binding motif protein, X-linked
chr6_+_88106840 0.02 ENST00000369570.4
C6orf164
chromosome 6 open reading frame 164
chr14_+_88852059 0.02 ENST00000045347.7
SPATA7
spermatogenesis associated 7
chr13_+_51483814 0.01 ENST00000336617.3
ENST00000422660.1
RNASEH2B
ribonuclease H2, subunit B
chr2_+_170683979 0.01 ENST00000418381.1
UBR3
ubiquitin protein ligase E3 component n-recognin 3 (putative)
chr12_-_122751002 0.01 ENST00000267199.4
VPS33A
vacuolar protein sorting 33 homolog A (S. cerevisiae)
chr10_+_86184676 0.01 ENST00000543283.1
CCSER2
coiled-coil serine-rich protein 2
chr10_+_96305535 0.01 ENST00000419900.1
ENST00000348459.5
ENST00000394045.1
ENST00000394044.1
ENST00000394036.1
HELLS
helicase, lymphoid-specific
chr11_+_67250490 0.01 ENST00000528641.2
ENST00000279146.3
AIP
aryl hydrocarbon receptor interacting protein
chr1_+_104104379 0.01 ENST00000435302.1
AMY2B
amylase, alpha 2B (pancreatic)
chr18_-_14132422 0.01 ENST00000589498.1
ENST00000590202.1
ZNF519
zinc finger protein 519
chr2_-_130031335 0.01 ENST00000375987.3
AC079586.1
AC079586.1
chr15_+_30427352 0.01 ENST00000569052.1
GOLGA8T
golgin A8 family, member T
chr17_-_26220366 0.01 ENST00000460380.2
ENST00000508862.1
ENST00000379102.3
ENST00000582441.1
LYRM9
RP1-66C13.4
LYR motif containing 9
Uncharacterized protein
chr16_+_53483983 0.01 ENST00000544545.1
RBL2
retinoblastoma-like 2 (p130)
chr20_+_46130601 0.01 ENST00000341724.6
NCOA3
nuclear receptor coactivator 3
chr2_+_172543919 0.01 ENST00000452242.1
ENST00000340296.4
DYNC1I2
dynein, cytoplasmic 1, intermediate chain 2
chr2_+_172544011 0.01 ENST00000508530.1
DYNC1I2
dynein, cytoplasmic 1, intermediate chain 2
chr13_+_50656307 0.01 ENST00000378180.4
DLEU1
deleted in lymphocytic leukemia 1 (non-protein coding)
chr9_-_86955598 0.01 ENST00000376238.4
SLC28A3
solute carrier family 28 (concentrative nucleoside transporter), member 3
chr12_-_10541575 0.01 ENST00000540818.1
KLRK1
killer cell lectin-like receptor subfamily K, member 1
chr9_-_34397800 0.01 ENST00000297623.2
C9orf24
chromosome 9 open reading frame 24
chr2_+_177134134 0.01 ENST00000249442.6
ENST00000392529.2
ENST00000443241.1
MTX2
metaxin 2
chr15_+_58702742 0.00 ENST00000356113.6
ENST00000414170.3
LIPC
lipase, hepatic
chrX_+_1710484 0.00 ENST00000313871.3
ENST00000381261.3
AKAP17A
A kinase (PRKA) anchor protein 17A
chr14_+_37641012 0.00 ENST00000556667.1
SLC25A21-AS1
SLC25A21 antisense RNA 1
chr11_+_69455855 0.00 ENST00000227507.2
ENST00000536559.1
CCND1
cyclin D1
chr6_-_127664736 0.00 ENST00000368291.2
ENST00000309620.9
ENST00000454859.3
ECHDC1
enoyl CoA hydratase domain containing 1
chr3_+_137728842 0.00 ENST00000183605.5
CLDN18
claudin 18
chr19_-_38146289 0.00 ENST00000392144.1
ENST00000591444.1
ENST00000351218.2
ENST00000587809.1
ZFP30
ZFP30 zinc finger protein
chr3_-_157221128 0.00 ENST00000392833.2
ENST00000362010.2
VEPH1
ventricular zone expressed PH domain-containing 1
chr18_+_11851383 0.00 ENST00000526991.2
CHMP1B
charged multivesicular body protein 1B
chr6_-_32908765 0.00 ENST00000416244.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chrX_-_77150985 0.00 ENST00000358075.6
MAGT1
magnesium transporter 1
chrX_-_135962923 0.00 ENST00000565438.1
RBMX
RNA binding motif protein, X-linked
chr1_+_227751281 0.00 ENST00000440339.1
ZNF678
zinc finger protein 678
chr16_+_66442411 0.00 ENST00000499966.1
LINC00920
long intergenic non-protein coding RNA 920
chr15_-_70994612 0.00 ENST00000558758.1
ENST00000379983.2
ENST00000560441.1
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr18_-_21017817 0.00 ENST00000542162.1
ENST00000383233.3
ENST00000582336.1
ENST00000450466.2
ENST00000578520.1
ENST00000399707.1
TMEM241
transmembrane protein 241
chr10_-_62332357 0.00 ENST00000503366.1
ANK3
ankyrin 3, node of Ranvier (ankyrin G)

Network of associatons between targets according to the STRING database.

First level regulatory network of HMGA2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0043397 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.0 0.1 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0051733 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.0 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)