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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)
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Results for HIVEP1
Z-value: 1.27
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Transcription factors associated with HIVEP1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| HIVEP1 | hg19_v2_chr6_+_12012536_12012571 | -0.67 | 3.3e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of HIVEP1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.9 | GO:0030208 | dermatan sulfate biosynthetic process(GO:0030208) |
| 0.4 | 1.8 | GO:1901545 | cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545) |
| 0.1 | 1.7 | GO:0090385 | phagosome-lysosome fusion(GO:0090385) |
| 0.2 | 1.3 | GO:0061086 | negative regulation of histone H3-K27 methylation(GO:0061086) |
| 0.1 | 1.3 | GO:0019264 | glycine biosynthetic process from serine(GO:0019264) |
| 0.4 | 1.2 | GO:0014859 | negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723) |
| 0.1 | 1.2 | GO:0006701 | progesterone biosynthetic process(GO:0006701) |
| 0.1 | 1.2 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
| 0.1 | 0.8 | GO:0002084 | protein depalmitoylation(GO:0002084) |
| 0.0 | 0.8 | GO:1904659 | hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.0 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.0 | 1.7 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
| 0.1 | 1.3 | GO:0070552 | BRISC complex(GO:0070552) |
| 0.0 | 1.3 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.0 | 1.1 | GO:0044232 | organelle membrane contact site(GO:0044232) |
| 0.1 | 0.8 | GO:0005677 | chromatin silencing complex(GO:0005677) |
| 0.0 | 0.7 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
| 0.1 | 0.6 | GO:0031933 | telomeric heterochromatin(GO:0031933) |
| 0.1 | 0.6 | GO:0005610 | laminin-5 complex(GO:0005610) |
| 0.0 | 0.6 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.0 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 0.1 | 1.9 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.1 | 1.7 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.1 | 1.3 | GO:0004793 | glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732) |
| 0.0 | 1.3 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.1 | 1.2 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 0.0 | 1.2 | GO:0017127 | cholesterol transporter activity(GO:0017127) |
| 0.1 | 0.8 | GO:0098599 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
| 0.2 | 0.6 | GO:0046969 | histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969) |
| 0.1 | 0.6 | GO:0004045 | aminoacyl-tRNA hydrolase activity(GO:0004045) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.9 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 1.1 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.0 | 0.5 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.0 | 0.5 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.0 | 0.5 | SA PTEN PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |
| 0.0 | 0.4 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.0 | 0.4 | PID IL8 CXCR1 PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.1 | 0.1 | PID NFKAPPAB ATYPICAL PATHWAY | Atypical NF-kappaB pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.9 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.1 | 1.8 | REACTOME DESTABILIZATION OF MRNA BY BRF1 | Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1) |
| 0.0 | 0.7 | REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI | Genes involved in RIP-mediated NFkB activation via DAI |
| 0.0 | 0.6 | REACTOME INFLAMMASOMES | Genes involved in Inflammasomes |
| 0.0 | 0.6 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.0 | 0.6 | REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter |
| 0.0 | 0.5 | REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL | Genes involved in AKT phosphorylates targets in the cytosol |
| 0.0 | 0.5 | REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA | Genes involved in G beta:gamma signalling through PLC beta |
| 0.0 | 0.4 | REACTOME DSCAM INTERACTIONS | Genes involved in DSCAM interactions |
| 0.0 | 0.4 | REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS | Genes involved in Thrombin signalling through proteinase activated receptors (PARs) |