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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for HIF1A

Z-value: 0.82

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Transcription factors associated with HIF1A

Gene Symbol Gene ID Gene Info
ENSG00000100644.12 hypoxia inducible factor 1 subunit alpha

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HIF1Ahg19_v2_chr14_+_62162258_621622690.927.9e-02Click!

Activity profile of HIF1A motif

Sorted Z-values of HIF1A motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_150254936 0.52 ENST00000447007.1
ENST00000369095.1
ENST00000369094.1
chromosome 1 open reading frame 51
chr4_-_4291761 0.43 ENST00000513174.1
Ly1 antibody reactive
chr12_+_131356582 0.39 ENST00000448750.3
ENST00000541630.1
ENST00000392369.2
ENST00000254675.3
ENST00000535090.1
ENST00000392367.3
RAN, member RAS oncogene family
chr2_-_232328867 0.36 ENST00000453992.1
ENST00000417652.1
ENST00000454824.1
nucleolin
chr11_-_74204692 0.35 ENST00000528085.1
lipoyl(octanoyl) transferase 2 (putative)
chr18_+_56531584 0.32 ENST00000590287.1
zinc finger protein 532
chr17_-_46690839 0.32 ENST00000498634.2
homeobox B8
chr14_+_56046990 0.32 ENST00000438792.2
ENST00000395314.3
ENST00000395308.1
kinectin 1 (kinesin receptor)
chr6_-_153304697 0.29 ENST00000367241.3
F-box protein 5
chr3_-_145878954 0.29 ENST00000282903.5
ENST00000360060.3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr14_-_92572894 0.29 ENST00000532032.1
ENST00000506466.1
ENST00000555381.1
ENST00000557311.1
ENST00000554592.1
ENST00000554672.1
ENST00000553491.1
ENST00000556220.1
ENST00000502250.1
ENST00000503767.1
ENST00000393287.5
ENST00000340660.6
ENST00000545170.1
ENST00000429774.2
ataxin 3
chr6_-_153304148 0.27 ENST00000229758.3
F-box protein 5
chr19_+_1407733 0.27 ENST00000592453.1
DAZ associated protein 1
chr13_-_52027134 0.26 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
integrator complex subunit 6
chr8_-_97273807 0.26 ENST00000517720.1
ENST00000287025.3
ENST00000523821.1
MTERF domain containing 1
chr1_-_26233423 0.26 ENST00000357865.2
stathmin 1
chr5_+_49962772 0.26 ENST00000281631.5
ENST00000513738.1
ENST00000503665.1
ENST00000514067.2
ENST00000503046.1
poly (ADP-ribose) polymerase family, member 8
chr1_-_231376836 0.25 ENST00000451322.1
chromosome 1 open reading frame 131
chr3_+_133292759 0.25 ENST00000431519.2
CDV3 homolog (mouse)
chr14_+_64970662 0.25 ENST00000556965.1
ENST00000554015.1
zinc finger and BTB domain containing 1
chr11_+_74204395 0.24 ENST00000526036.1
AP001372.2
chr14_+_56046914 0.24 ENST00000413890.2
ENST00000395309.3
ENST00000554567.1
ENST00000555498.1
kinectin 1 (kinesin receptor)
chr7_-_127032114 0.24 ENST00000436992.1
zinc finger protein 800
chr4_-_104119528 0.23 ENST00000380026.3
ENST00000503705.1
ENST00000265148.3
centromere protein E, 312kDa
chr4_-_4291748 0.23 ENST00000452476.1
Ly1 antibody reactive
chr16_-_81129951 0.23 ENST00000315467.3
glycine cleavage system protein H (aminomethyl carrier)
chr12_+_46777450 0.23 ENST00000551503.1
RP11-96H19.1
chr2_+_173420697 0.23 ENST00000282077.3
ENST00000392571.2
ENST00000410055.1
pyruvate dehydrogenase kinase, isozyme 1
chr3_+_133292851 0.22 ENST00000503932.1
CDV3 homolog (mouse)
chr1_+_112162381 0.22 ENST00000433097.1
ENST00000369709.3
ENST00000436150.2
RAP1A, member of RAS oncogene family
chr4_-_104119488 0.22 ENST00000514974.1
centromere protein E, 312kDa
chr14_+_64970427 0.22 ENST00000553583.1
zinc finger and BTB domain containing 1
chr8_+_97274119 0.21 ENST00000455950.2
phosphatidylserine synthase 1
chr12_+_123849462 0.21 ENST00000543072.1
hsa-mir-8072
chr3_+_100211412 0.21 ENST00000323523.4
ENST00000403410.1
ENST00000449609.1
transmembrane protein 45A
chr15_+_44084503 0.21 ENST00000409960.2
ENST00000409646.1
ENST00000594896.1
ENST00000339624.5
ENST00000409291.1
ENST00000402131.1
ENST00000403425.1
ENST00000430901.1
small EDRK-rich factor 2
chr13_+_25875785 0.20 ENST00000381747.3
nucleoporin like 1
chr15_+_44084040 0.20 ENST00000249786.4
small EDRK-rich factor 2
chr1_+_193091080 0.20 ENST00000367435.3
cell division cycle 73
chr4_-_4291861 0.20 ENST00000343470.4
Ly1 antibody reactive
chr3_+_19988885 0.20 ENST00000422242.1
RAB5A, member RAS oncogene family
chr13_-_28024681 0.19 ENST00000381116.1
ENST00000381120.3
ENST00000431572.2
mitochondrial translational initiation factor 3
chr13_-_36788718 0.19 ENST00000317764.6
ENST00000379881.3
spermatogenesis and oogenesis specific basic helix-loop-helix 2
chrX_-_41782683 0.19 ENST00000378163.1
ENST00000378154.1
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
chr8_+_109455845 0.19 ENST00000220853.3
ER membrane protein complex subunit 2
chr4_-_39529049 0.18 ENST00000501493.2
ENST00000509391.1
ENST00000507089.1
UDP-glucose 6-dehydrogenase
chr8_-_95908902 0.18 ENST00000520509.1
cyclin E2
chr1_-_26232951 0.18 ENST00000426559.2
ENST00000455785.2
stathmin 1
chr4_-_39529180 0.18 ENST00000515021.1
ENST00000510490.1
ENST00000316423.6
UDP-glucose 6-dehydrogenase
chr5_+_138609441 0.18 ENST00000509990.1
ENST00000506147.1
ENST00000512107.1
matrin 3
chr9_-_94186131 0.18 ENST00000297689.3
nuclear factor, interleukin 3 regulated
chr8_-_54755459 0.17 ENST00000524234.1
ENST00000521275.1
ENST00000396774.2
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr1_-_235324530 0.17 ENST00000447801.1
ENST00000366606.3
ENST00000429912.1
RNA binding motif protein 34
chr13_+_115079949 0.17 ENST00000361283.1
chromosome alignment maintaining phosphoprotein 1
chr8_+_98656693 0.17 ENST00000519934.1
metadherin
chr7_+_96747030 0.17 ENST00000360382.4
ACN9 homolog (S. cerevisiae)
chr4_+_76649797 0.17 ENST00000538159.1
ENST00000514213.2
USO1 vesicle transport factor
chr2_+_85132749 0.17 ENST00000233143.4
thymosin beta 10
chr11_+_73498898 0.17 ENST00000535529.1
ENST00000497094.2
ENST00000411840.2
ENST00000535277.1
ENST00000398483.3
ENST00000542303.1
mitochondrial ribosomal protein L48
chr16_-_68269971 0.17 ENST00000565858.1
epithelial splicing regulatory protein 2
chr22_+_35653445 0.17 ENST00000420166.1
ENST00000444518.2
ENST00000455359.1
ENST00000216106.5
HMG box domain containing 4
chr17_+_27052892 0.17 ENST00000579671.1
ENST00000579060.1
NIMA-related kinase 8
chrX_+_100663243 0.17 ENST00000316594.5
heterogeneous nuclear ribonucleoprotein H2 (H')
chr13_+_27998681 0.17 ENST00000381140.4
general transcription factor IIIA
chr3_-_195808952 0.17 ENST00000540528.1
ENST00000392396.3
ENST00000535031.1
ENST00000420415.1
transferrin receptor
chr11_-_73471655 0.16 ENST00000400470.2
RAB6A, member RAS oncogene family
chr7_+_100318423 0.16 ENST00000252723.2
erythropoietin
chr7_-_102985035 0.16 ENST00000426036.2
ENST00000249270.7
ENST00000454277.1
ENST00000412522.1
DnaJ (Hsp40) homolog, subfamily C, member 2
chr8_-_125551278 0.16 ENST00000519232.1
ENST00000523888.1
ENST00000522810.1
ENST00000519548.1
ENST00000517678.1
ENST00000605953.1
ENST00000276692.6
TatD DNase domain containing 1
chr3_-_19988462 0.16 ENST00000344838.4
EF-hand domain family, member B
chr7_+_86781778 0.16 ENST00000432937.2
cyclin D binding myb-like transcription factor 1
chrX_-_34675391 0.16 ENST00000275954.3
transmembrane protein 47
chr17_-_35969409 0.16 ENST00000394378.2
ENST00000585472.1
ENST00000591288.1
ENST00000502449.2
ENST00000345615.4
ENST00000346661.4
ENST00000585689.1
ENST00000339208.6
synergin, gamma
chr2_+_242254679 0.16 ENST00000428282.1
ENST00000360051.3
septin 2
chr1_-_26232522 0.16 ENST00000399728.1
stathmin 1
chr16_+_66914264 0.16 ENST00000311765.2
ENST00000568869.1
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr2_+_187350973 0.16 ENST00000544130.1
zinc finger CCCH-type containing 15
chr14_-_53162361 0.16 ENST00000395686.3
ERO1-like (S. cerevisiae)
chr1_-_166136187 0.15 ENST00000338353.3
family with sequence similarity 78, member B
chr15_+_52311398 0.15 ENST00000261845.5
mitogen-activated protein kinase 6
chr10_-_16859361 0.15 ENST00000377921.3
Ras suppressor protein 1
chr4_+_4291924 0.15 ENST00000355834.3
ENST00000337872.4
ENST00000538529.1
ENST00000502918.1
zinc finger and BTB domain containing 49
chr11_+_73498973 0.15 ENST00000537007.1
mitochondrial ribosomal protein L48
chr11_-_46141338 0.15 ENST00000529782.1
ENST00000532010.1
ENST00000525438.1
ENST00000533757.1
ENST00000527782.1
PHD finger protein 21A
chr7_-_27135591 0.15 ENST00000343060.4
ENST00000355633.5
homeobox A1
chr18_-_45457478 0.15 ENST00000402690.2
ENST00000356825.4
SMAD family member 2
chr9_+_4490394 0.15 ENST00000262352.3
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr5_-_131563474 0.15 ENST00000417528.1
prolyl 4-hydroxylase, alpha polypeptide II
chr1_+_246729815 0.14 ENST00000366511.1
consortin, connexin sorting protein
chr22_+_19702069 0.14 ENST00000412544.1
septin 5
chr16_-_81129845 0.14 ENST00000569885.1
ENST00000566566.1
glycine cleavage system protein H (aminomethyl carrier)
chr11_+_18343800 0.14 ENST00000453096.2
general transcription factor IIH, polypeptide 1, 62kDa
chr12_-_123849374 0.14 ENST00000602398.1
ENST00000602750.1
strawberry notch homolog 1 (Drosophila)
chr2_+_32288657 0.14 ENST00000345662.1
spastin
chr11_+_33279850 0.14 ENST00000531504.1
ENST00000456517.1
homeodomain interacting protein kinase 3
chr8_+_95908041 0.14 ENST00000396113.1
ENST00000519136.1
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr12_-_2113583 0.14 ENST00000397173.4
ENST00000280665.6
decapping mRNA 1B
chr2_+_242254507 0.14 ENST00000391973.2
septin 2
chrX_-_13956497 0.14 ENST00000398361.3
glycoprotein M6B
chr1_-_166135952 0.14 ENST00000354422.3
family with sequence similarity 78, member B
chrX_+_16804544 0.14 ENST00000380122.5
ENST00000398155.4
taxilin gamma
chr18_+_56530794 0.14 ENST00000590285.1
ENST00000586085.1
ENST00000589288.1
zinc finger protein 532
chr1_-_113498616 0.14 ENST00000433570.4
ENST00000538576.1
ENST00000458229.1
solute carrier family 16 (monocarboxylate transporter), member 1
chr17_-_57184064 0.14 ENST00000262294.7
tripartite motif containing 37
chr10_-_16859442 0.14 ENST00000602389.1
ENST00000345264.5
Ras suppressor protein 1
chr10_+_49514698 0.14 ENST00000432379.1
ENST00000429041.1
ENST00000374189.1
mitogen-activated protein kinase 8
chr2_-_232329186 0.14 ENST00000322723.4
nucleolin
chr2_+_30370382 0.14 ENST00000402708.1
yippee-like 5 (Drosophila)
chr19_+_2164173 0.14 ENST00000452696.1
DOT1-like histone H3K79 methyltransferase
chr13_-_28024269 0.13 ENST00000405591.2
mitochondrial translational initiation factor 3
chr17_+_65373531 0.13 ENST00000580974.1
phosphatidylinositol transfer protein, cytoplasmic 1
chr11_+_76156045 0.13 ENST00000533988.1
ENST00000524490.1
ENST00000334736.3
ENST00000343878.3
ENST00000533972.1
chromosome 11 open reading frame 30
chrX_+_69509870 0.13 ENST00000374388.3
kinesin family member 4A
chr14_+_96968802 0.13 ENST00000556619.1
ENST00000392990.2
poly(A) polymerase alpha
chr1_-_113498943 0.13 ENST00000369626.3
solute carrier family 16 (monocarboxylate transporter), member 1
chr15_+_43622843 0.13 ENST00000428046.3
ENST00000422466.2
ENST00000389651.4
adenosine deaminase-like
chr5_+_61602236 0.13 ENST00000514082.1
ENST00000407818.3
kinesin heavy chain member 2A
chr10_-_49732281 0.13 ENST00000374170.1
Rho GTPase activating protein 22
chr4_+_152020715 0.13 ENST00000274065.4
ribosomal protein S3A
chr6_-_114292449 0.13 ENST00000519065.1
histone deacetylase 2
chr15_+_74908147 0.13 ENST00000568139.1
ENST00000563297.1
ENST00000568488.1
ENST00000352989.5
ENST00000348245.3
CDC-like kinase 3
chr20_+_48552908 0.13 ENST00000244061.2
ring finger protein 114
chr2_+_187350883 0.13 ENST00000337859.6
zinc finger CCCH-type containing 15
chr15_+_101420028 0.13 ENST00000557963.1
ENST00000346623.6
aldehyde dehydrogenase 1 family, member A3
chr11_+_18344106 0.13 ENST00000534641.1
ENST00000525831.1
ENST00000265963.4
general transcription factor IIH, polypeptide 1, 62kDa
chr2_+_192543694 0.12 ENST00000435931.1
nucleic acid binding protein 1
chr11_-_76155618 0.12 ENST00000530759.1
RP11-111M22.3
chr10_+_180643 0.12 ENST00000509513.2
ENST00000397959.3
zinc finger, MYND-type containing 11
chr2_+_32288725 0.12 ENST00000315285.3
spastin
chr4_+_17578815 0.12 ENST00000226299.4
leucine aminopeptidase 3
chr2_+_28113583 0.12 ENST00000344773.2
ENST00000379624.1
ENST00000342045.2
ENST00000379632.2
ENST00000361704.2
brain and reproductive organ-expressed (TNFRSF1A modulator)
chr11_+_7534999 0.12 ENST00000528947.1
ENST00000299492.4
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr14_+_96968707 0.12 ENST00000216277.8
ENST00000557320.1
ENST00000557471.1
poly(A) polymerase alpha
chr1_-_231376867 0.12 ENST00000366649.2
ENST00000318906.2
ENST00000366651.3
chromosome 1 open reading frame 131
chr10_+_75910960 0.12 ENST00000539909.1
ENST00000286621.2
adenosine kinase
chr3_-_195808980 0.12 ENST00000360110.4
transferrin receptor
chr12_+_72148614 0.12 ENST00000261263.3
RAB21, member RAS oncogene family
chr6_+_7727030 0.12 ENST00000283147.6
bone morphogenetic protein 6
chr19_-_663147 0.12 ENST00000606702.1
ring finger protein 126
chr10_+_120789223 0.12 ENST00000425699.1
nanos homolog 1 (Drosophila)
chr20_-_17662705 0.12 ENST00000455029.2
ribosome binding protein 1
chr2_+_118846008 0.11 ENST00000245787.4
insulin induced gene 2
chr8_-_101734308 0.11 ENST00000519004.1
ENST00000519363.1
ENST00000520142.1
poly(A) binding protein, cytoplasmic 1
chr2_+_88991162 0.11 ENST00000283646.4
ribose 5-phosphate isomerase A
chr18_+_9913977 0.11 ENST00000400000.2
ENST00000340541.4
VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr4_-_186317034 0.11 ENST00000505916.1
LRP2 binding protein
chr2_+_192543153 0.11 ENST00000425611.2
nucleic acid binding protein 1
chr1_+_28052518 0.11 ENST00000530324.1
ENST00000234549.7
ENST00000373949.1
ENST00000010299.6
family with sequence similarity 76, member A
chr7_+_94536898 0.11 ENST00000433360.1
ENST00000340694.4
ENST00000424654.1
protein phosphatase 1, regulatory subunit 9A
chr4_+_152020736 0.11 ENST00000509736.1
ENST00000505243.1
ENST00000514682.1
ENST00000322686.6
ENST00000503002.1
ribosomal protein S3A
chr19_+_50180507 0.11 ENST00000454376.2
ENST00000524771.1
protein arginine methyltransferase 1
chr5_+_61601965 0.11 ENST00000401507.3
kinesin heavy chain member 2A
chr15_+_89182178 0.11 ENST00000559876.1
interferon stimulated exonuclease gene 20kDa
chr16_+_69166770 0.11 ENST00000567235.2
ENST00000568448.1
cirrhosis, autosomal recessive 1A (cirhin)
chr4_-_492891 0.11 ENST00000338977.5
ENST00000511833.2
zinc finger protein 721
chr2_-_40006289 0.11 ENST00000260619.6
ENST00000454352.2
THUMP domain containing 2
chr15_+_76135622 0.11 ENST00000338677.4
ENST00000267938.4
ENST00000569423.1
ubiquitin-conjugating enzyme E2Q family member 2
chr15_+_89181974 0.11 ENST00000306072.5
interferon stimulated exonuclease gene 20kDa
chr2_-_42721110 0.11 ENST00000394973.4
ENST00000306078.1
potassium voltage-gated channel, subfamily G, member 3
chr19_+_19516561 0.11 ENST00000457895.2
GATA zinc finger domain containing 2A
chrX_-_102941596 0.11 ENST00000441076.2
ENST00000422355.1
ENST00000442614.1
ENST00000422154.2
ENST00000451301.1
mortality factor 4 like 2
chr16_+_53164833 0.10 ENST00000564845.1
chromodomain helicase DNA binding protein 9
chr7_+_26331541 0.10 ENST00000416246.1
ENST00000338523.4
ENST00000412416.1
sorting nexin 10
chr3_+_63898275 0.10 ENST00000538065.1
ataxin 7
chr17_-_5342380 0.10 ENST00000225698.4
complement component 1, q subcomponent binding protein
chr8_-_30515693 0.10 ENST00000355904.4
general transcription factor IIE, polypeptide 2, beta 34kDa
chr7_-_92465868 0.10 ENST00000424848.2
cyclin-dependent kinase 6
chr4_+_152020789 0.10 ENST00000512690.1
ENST00000508783.1
ENST00000512797.1
ENST00000507327.1
ENST00000515792.1
ENST00000506126.1
ribosomal protein S3A
chr6_+_35265586 0.10 ENST00000542066.1
ENST00000316637.5
differentially expressed in FDCP 6 homolog (mouse)
chr17_+_80477571 0.10 ENST00000335255.5
forkhead box K2
chr17_-_8534031 0.10 ENST00000411957.1
ENST00000396239.1
ENST00000379980.4
myosin, heavy chain 10, non-muscle
chr18_+_43913919 0.10 ENST00000587853.1
ring finger protein 165
chr10_-_75910789 0.10 ENST00000355264.4
adaptor-related protein complex 3, mu 1 subunit
chr15_+_38544476 0.10 ENST00000299084.4
sprouty-related, EVH1 domain containing 1
chr11_+_9595180 0.10 ENST00000450114.2
WEE1 G2 checkpoint kinase
chr2_-_242254595 0.10 ENST00000441124.1
ENST00000391976.2
high density lipoprotein binding protein
chr17_-_17942473 0.10 ENST00000585101.1
ENST00000474627.3
ENST00000444058.1
ATP synthase mitochondrial F1 complex assembly factor 2
chr12_-_21810765 0.10 ENST00000450584.1
ENST00000350669.1
lactate dehydrogenase B
chr8_+_26240414 0.10 ENST00000380629.2
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr2_+_216176761 0.10 ENST00000540518.1
ENST00000435675.1
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr3_-_71632894 0.10 ENST00000493089.1
forkhead box P1
chr6_+_151561506 0.10 ENST00000253332.1
A kinase (PRKA) anchor protein 12
chr3_+_52719936 0.10 ENST00000418458.1
ENST00000394799.2
guanine nucleotide binding protein-like 3 (nucleolar)
chr14_-_88459503 0.09 ENST00000393568.4
ENST00000261304.2
galactosylceramidase
chr1_+_14026671 0.09 ENST00000484063.2
PR domain containing 2, with ZNF domain
chr10_+_23728198 0.09 ENST00000376495.3
OTU domain containing 1
chr2_-_98612379 0.09 ENST00000425805.2
transmembrane protein 131
chr11_-_122931881 0.09 ENST00000526110.1
ENST00000227378.3
heat shock 70kDa protein 8
chr2_+_10183651 0.09 ENST00000305883.1
Kruppel-like factor 11
chr8_+_6566206 0.09 ENST00000518327.1
1-acylglycerol-3-phosphate O-acyltransferase 5
chrX_+_105969893 0.09 ENST00000255499.2
ring finger protein 128, E3 ubiquitin protein ligase
chr17_-_57184260 0.09 ENST00000376149.3
ENST00000393066.3
tripartite motif containing 37
chr7_+_86781677 0.09 ENST00000331242.7
ENST00000394702.3
ENST00000413276.2
ENST00000446796.2
ENST00000411766.2
ENST00000420131.1
ENST00000414630.2
ENST00000453049.1
ENST00000428819.1
ENST00000448598.1
ENST00000449088.3
ENST00000430405.3
cyclin D binding myb-like transcription factor 1
chr7_+_36192758 0.09 ENST00000242108.4
endonuclease/exonuclease/phosphatase family domain containing 1
chr17_+_5185552 0.09 ENST00000262477.6
ENST00000408982.2
ENST00000575991.1
ENST00000537505.1
ENST00000546142.2
rabaptin, RAB GTPase binding effector protein 1
chr7_-_95951334 0.09 ENST00000265631.5
solute carrier family 25 (aspartate/glutamate carrier), member 13
chr14_+_96000930 0.09 ENST00000331334.4
glutaredoxin 5
chr1_-_220101944 0.09 ENST00000366926.3
ENST00000536992.1
solute carrier family 30, member 10
chr10_+_180987 0.09 ENST00000381591.1
zinc finger, MYND-type containing 11
chr6_+_108487245 0.09 ENST00000368986.4
nuclear receptor subfamily 2, group E, member 1

Network of associatons between targets according to the STRING database.

First level regulatory network of HIF1A

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
0.1 0.4 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.1 0.5 GO:2000174 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.1 0.3 GO:0015728 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.1 0.6 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 0.4 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.3 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 0.2 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.1 0.3 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.1 0.5 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.1 0.3 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.1 0.2 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.1 0.2 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 0.3 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.1 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.0 0.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.1 GO:0006154 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.0 0.1 GO:0060166 olfactory pit development(GO:0060166)
0.0 0.1 GO:0044209 AMP salvage(GO:0044209)
0.0 0.1 GO:1900153 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.2 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.0 0.2 GO:2000301 response to antineoplastic agent(GO:0097327) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.4 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.0 0.3 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.1 GO:0034226 lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
0.0 0.2 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.0 0.2 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.2 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.0 0.2 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.5 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.1 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.0 0.1 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.3 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.1 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.0 0.2 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.0 0.3 GO:0051013 microtubule severing(GO:0051013)
0.0 0.3 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.2 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.1 GO:0090031 positive regulation of steroid hormone biosynthetic process(GO:0090031)
0.0 0.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.2 GO:0021592 fourth ventricle development(GO:0021592)
0.0 0.2 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.1 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.0 0.1 GO:1902904 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.0 0.1 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.1 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.1 GO:0070272 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 0.1 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.1 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.2 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.2 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.3 GO:0046852 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.0 0.1 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.2 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.1 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0 0.1 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.3 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.1 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.1 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.2 GO:0050812 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.2 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.0 0.1 GO:1904693 negative regulation of mitotic cell cycle, embryonic(GO:0045976) midbrain morphogenesis(GO:1904693)
0.0 0.1 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.0 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.2 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.3 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.2 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.0 GO:0018277 protein deamination(GO:0018277)
0.0 0.1 GO:0045007 depurination(GO:0045007)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0042565 RNA nuclear export complex(GO:0042565)
0.1 0.4 GO:0005960 glycine cleavage complex(GO:0005960)
0.1 0.2 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 0.2 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.2 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 0.2 GO:0097513 myosin II filament(GO:0097513)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.2 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.3 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.1 GO:1905202 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.0 0.5 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.1 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.3 GO:0097227 sperm annulus(GO:0097227)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.1 0.3 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 0.4 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.1 0.3 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.1 0.3 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.1 0.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.5 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.1 0.6 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.1 0.2 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.0 0.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.5 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.0 0.1 GO:0030984 kininogen binding(GO:0030984)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.2 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.2 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.0 0.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.2 GO:0071253 connexin binding(GO:0071253)
0.0 0.3 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.2 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.1 GO:0005287 high-affinity basic amino acid transmembrane transporter activity(GO:0005287) high-affinity arginine transmembrane transporter activity(GO:0005289) high-affinity lysine transmembrane transporter activity(GO:0005292)
0.0 0.1 GO:0032408 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.0 GO:0070123 transforming growth factor beta receptor activity, type III(GO:0070123)
0.0 0.0 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.4 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)
0.0 0.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.1 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.1 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.4 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.4 PID PLK1 PATHWAY PLK1 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.6 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.4 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.5 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex