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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for HDX

Z-value: 0.26

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Transcription factors associated with HDX

Gene Symbol Gene ID Gene Info
HDX
ENSG00000165259.9 highly divergent homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HDXhg19_v2_chrX_-_83757399_837574870.918.7e-02Click!

Activity profile of HDX motif

Sorted Z-values of HDX motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_102758210 0.09 ENST00000450319.1
IL1R1
interleukin 1 receptor, type I
chrX_+_100224676 0.07 ENST00000450049.2
ARL13A
ADP-ribosylation factor-like 13A
chr1_+_84629976 0.07 ENST00000446538.1
ENST00000370684.1
ENST00000436133.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr7_-_139756791 0.07 ENST00000489809.1
PARP12
poly (ADP-ribose) polymerase family, member 12
chr16_+_1877204 0.07 ENST00000427358.2
FAHD1
fumarylacetoacetate hydrolase domain containing 1
chr3_-_51533966 0.07 ENST00000504652.1
VPRBP
Vpr (HIV-1) binding protein
chr10_-_21186144 0.06 ENST00000377119.1
NEBL
nebulette
chr2_-_113594279 0.05 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
IL1B
interleukin 1, beta
chr19_+_36602104 0.05 ENST00000585332.1
ENST00000262637.4
OVOL3
ovo-like zinc finger 3
chr7_-_107883678 0.04 ENST00000417701.1
NRCAM
neuronal cell adhesion molecule
chr12_-_118797475 0.04 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
TAOK3
TAO kinase 3
chr19_-_58485895 0.04 ENST00000314391.3
C19orf18
chromosome 19 open reading frame 18
chr1_-_48866517 0.04 ENST00000371841.1
SPATA6
spermatogenesis associated 6
chr14_+_71788096 0.04 ENST00000557151.1
SIPA1L1
signal-induced proliferation-associated 1 like 1
chr14_+_79745682 0.04 ENST00000557594.1
NRXN3
neurexin 3
chr1_+_84630367 0.03 ENST00000370680.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr3_-_165555200 0.03 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
BCHE
butyrylcholinesterase
chr1_+_117602925 0.03 ENST00000369466.4
TTF2
transcription termination factor, RNA polymerase II
chr2_+_102758271 0.03 ENST00000428279.1
IL1R1
interleukin 1 receptor, type I
chr2_+_149447783 0.03 ENST00000449013.1
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr5_+_157602404 0.03 ENST00000522975.1
CTC-436K13.1
CTC-436K13.1
chr7_-_135412925 0.03 ENST00000354042.4
SLC13A4
solute carrier family 13 (sodium/sulfate symporter), member 4
chr5_-_135290651 0.03 ENST00000522943.1
ENST00000514447.2
LECT2
leukocyte cell-derived chemotaxin 2
chr9_+_6215799 0.02 ENST00000417746.2
ENST00000456383.2
IL33
interleukin 33
chr14_+_79745746 0.02 ENST00000281127.7
NRXN3
neurexin 3
chr19_-_41934635 0.02 ENST00000321702.2
B3GNT8
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
chr1_+_84630352 0.02 ENST00000450730.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr14_+_79746249 0.02 ENST00000428277.2
NRXN3
neurexin 3
chr11_+_9685604 0.02 ENST00000447399.2
ENST00000318950.6
SWAP70
SWAP switching B-cell complex 70kDa subunit
chr11_+_123900297 0.02 ENST00000431524.1
OR10G8
olfactory receptor, family 10, subfamily G, member 8
chr10_-_14372870 0.02 ENST00000357447.2
FRMD4A
FERM domain containing 4A
chr3_+_107241882 0.02 ENST00000416476.2
BBX
bobby sox homolog (Drosophila)
chr22_+_45714672 0.01 ENST00000424557.1
FAM118A
family with sequence similarity 118, member A
chr12_-_31743901 0.01 ENST00000354285.4
DENND5B
DENN/MADD domain containing 5B
chr1_-_169680745 0.01 ENST00000236147.4
SELL
selectin L
chr12_-_15815626 0.01 ENST00000540613.1
EPS8
epidermal growth factor receptor pathway substrate 8
chr2_+_128403439 0.01 ENST00000544369.1
GPR17
G protein-coupled receptor 17
chr13_+_24144796 0.01 ENST00000403372.2
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr5_+_60933634 0.01 ENST00000505642.1
C5orf64
chromosome 5 open reading frame 64
chr3_-_100565249 0.01 ENST00000495591.1
ENST00000383691.4
ENST00000466947.1
ABI3BP
ABI family, member 3 (NESH) binding protein
chr15_-_54025300 0.01 ENST00000559418.1
WDR72
WD repeat domain 72
chr2_+_169926047 0.00 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr18_-_53804580 0.00 ENST00000590484.1
ENST00000589293.1
ENST00000587904.1
ENST00000591974.1
RP11-456O19.4
RP11-456O19.4
chr1_+_75600567 0.00 ENST00000356261.3
LHX8
LIM homeobox 8
chr2_+_128403720 0.00 ENST00000272644.3
GPR17
G protein-coupled receptor 17
chrX_+_27608490 0.00 ENST00000451261.2
DCAF8L2
DDB1 and CUL4 associated factor 8-like 2
chr2_-_40657397 0.00 ENST00000408028.2
ENST00000332839.4
ENST00000406391.2
ENST00000542024.1
ENST00000542756.1
ENST00000405901.3
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr1_+_47489240 0.00 ENST00000371901.3
CYP4X1
cytochrome P450, family 4, subfamily X, polypeptide 1

Network of associatons between targets according to the STRING database.

First level regulatory network of HDX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.0 0.1 GO:0097338 response to clozapine(GO:0097338)
0.0 0.0 GO:0014016 neuroblast differentiation(GO:0014016)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.0 0.0 GO:0033265 choline binding(GO:0033265)
0.0 0.1 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)