ISMARA results: GUAAACA

Project

A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

Navigation

Downloads

Results for GUAAACA

Z-value: 2.16

Motif logo

miRNA associated with seed GUAAACA

Name	miRBASE accession
hsa-miR-30a-5p miRBase	MIMAT0000087
hsa-miR-30b-5p miRBase	MIMAT0000420
hsa-miR-30c-5p miRBase	MIMAT0000244
hsa-miR-30d-5p miRBase	MIMAT0000245
hsa-miR-30e-5p miRBase	MIMAT0000692

Activity profile of GUAAACA motif

Sorted Z-values of GUAAACA motif

Top targets:

Search:

Show entries

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr18_-_29264669 Show fit	0.81	ENST00000306851.5	B4GALT6 Ensembl NCBI GeneCards UniProt Show fit	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
chr15_-_78526942 Show fit	0.68	ENST00000258873.4	ACSBG1 Ensembl NCBI GeneCards UniProt Show fit	acyl-CoA synthetase bubblegum family member 1
chr22_+_33197683 Show fit	0.68	ENST00000266085.6	TIMP3 Ensembl NCBI GeneCards UniProt Show fit	TIMP metallopeptidase inhibitor 3
chr19_-_13068012 Show fit	0.67	ENST00000316939.1	GADD45GIP1 Ensembl NCBI GeneCards UniProt Show fit	growth arrest and DNA-damage-inducible, gamma interacting protein 1
chr8_-_103668114 Show fit	0.66	ENST00000285407.6	KLF10 Ensembl NCBI GeneCards UniProt Show fit	Kruppel-like factor 10
chr9_-_128003606 Show fit	0.66	ENST00000324460.6	HSPA5 Ensembl NCBI GeneCards UniProt Show fit	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
chr3_-_167452614 Show fit	0.62	ENST00000392750.2 ENST00000464360.1 ENST00000492139.1 ENST00000471885.1 ENST00000470131.1	PDCD10 Ensembl NCBI GeneCards UniProt Show fit	programmed cell death 10
chr15_+_27111510 Show fit	0.61	ENST00000335625.5	GABRA5 Ensembl NCBI GeneCards UniProt Show fit	gamma-aminobutyric acid (GABA) A receptor, alpha 5
chr12_-_76953284 Show fit	0.61	ENST00000547544.1 ENST00000393249.2	OSBPL8 Ensembl NCBI GeneCards UniProt Show fit	oxysterol binding protein-like 8
chr10_+_65281123 Show fit	0.61	ENST00000298249.4 ENST00000373758.4	REEP3 Ensembl NCBI GeneCards UniProt Show fit	receptor accessory protein 3

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of GUAAACA

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.1	GO:0070911	global genome nucleotide-excision repair(GO:0070911)
0.0	1.0	GO:0045022	early endosome to late endosome transport(GO:0045022)
0.0	0.9	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.3	0.8	GO:0021577	hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.1	0.8	GO:1903588	negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0	0.8	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0	0.8	GO:0045672	positive regulation of osteoclast differentiation(GO:0045672)
0.0	0.8	GO:0006270	DNA replication initiation(GO:0006270)
0.2	0.7	GO:1903984	positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.1	0.7	GO:1903862	positive regulation of oxidative phosphorylation(GO:1903862)

Showing 1 to 10 of 229 entries

Gene overrepresentation in cellular_component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.3	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	1.0	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	0.9	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
0.1	0.8	GO:0031089	platelet dense granule lumen(GO:0031089)
0.0	0.8	GO:1902711	GABA-A receptor complex(GO:1902711)
0.0	0.7	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.2	0.6	GO:0031372	UBC13-MMS2 complex(GO:0031372)
0.1	0.6	GO:0098837	postsynaptic recycling endosome(GO:0098837)
0.0	0.6	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.6	GO:0000815	ESCRT III complex(GO:0000815)

Showing 1 to 10 of 87 entries

Gene overrepresentation in molecular_function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.9	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.0	1.4	GO:0019003	GDP binding(GO:0019003)
0.0	1.0	GO:0061733	peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.1	0.9	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0	0.8	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0	0.8	GO:0004890	GABA-A receptor activity(GO:0004890)
0.0	0.8	GO:0031489	myosin V binding(GO:0031489)
0.0	0.8	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	0.8	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.1	0.7	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)

Showing 1 to 10 of 135 entries

Gene overrepresentation in C2:CP category:

Search:

Show entries

Total log-likelihood	Term	Description
1.7	PID RAS PATHWAY	Regulation of Ras family activation
1.3	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
1.2	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
1.1	PID NECTIN PATHWAY	Nectin adhesion pathway
0.9	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.6	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.5	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.4	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.4	PID IL5 PATHWAY	IL5-mediated signaling events
0.4	PID ALK2 PATHWAY	ALK2 signaling events

Showing 1 to 10 of 16 entries

Gene overrepresentation in C2:CP:REACTOME category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.1	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.9	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.9	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.8	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.8	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.8	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	0.7	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.0	0.7	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.6	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
0.0	0.6	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events

Showing 1 to 10 of 44 entries

Results for GUAAACA

Z-value: 2.16

Motif logo

miRNA associated with seed GUAAACA

Activity profile of GUAAACA motif

Sorted Z-values of GUAAACA motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of GUAAACA

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: