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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for GRHL1

Z-value: 0.33

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Transcription factors associated with GRHL1

Gene Symbol Gene ID Gene Info
ENSG00000134317.13 grainyhead like transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GRHL1hg19_v2_chr2_+_10091783_10091811-0.693.1e-01Click!

Activity profile of GRHL1 motif

Sorted Z-values of GRHL1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_17356697 0.18 ENST00000291442.3
nuclear receptor subfamily 2, group F, member 6
chr1_+_44440575 0.16 ENST00000532642.1
ENST00000236067.4
ENST00000471859.2
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr1_+_155023757 0.15 ENST00000356955.2
ENST00000449910.2
ENST00000359280.4
ENST00000360674.4
ENST00000368412.3
ENST00000355956.2
ENST00000368410.2
ENST00000271836.6
ENST00000368413.1
ENST00000531455.1
ENST00000447332.3
ADAM metallopeptidase domain 15
chr11_+_119038897 0.13 ENST00000454811.1
ENST00000449394.1
NLR family member X1
chr11_+_76493294 0.12 ENST00000533752.1
tsukushi, small leucine rich proteoglycan
chr1_-_52520828 0.12 ENST00000610127.1
thioredoxin domain containing 12 (endoplasmic reticulum)
chr11_+_119039414 0.11 ENST00000409991.1
ENST00000292199.2
ENST00000409265.4
ENST00000409109.1
NLR family member X1
chr6_+_168227552 0.09 ENST00000400825.4
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
chr21_+_33671264 0.09 ENST00000339944.4
melanocortin 2 receptor accessory protein
chr3_-_172241250 0.09 ENST00000420541.2
ENST00000241261.2
tumor necrosis factor (ligand) superfamily, member 10
chr19_+_45312310 0.09 ENST00000589651.1
basal cell adhesion molecule (Lutheran blood group)
chr19_-_291133 0.08 ENST00000327790.3
phosphatidic acid phosphatase type 2C
chr11_+_119039069 0.08 ENST00000422249.1
NLR family member X1
chr7_-_102283238 0.08 ENST00000340457.8
uroplakin 3B-like
chr7_-_102184083 0.08 ENST00000379357.5
polymerase (RNA) II (DNA directed) polypeptide J3
chr19_+_45312347 0.07 ENST00000270233.6
ENST00000591520.1
basal cell adhesion molecule (Lutheran blood group)
chr22_+_18560743 0.07 ENST00000399744.3
peroxisomal biogenesis factor 26
chr9_+_140122018 0.06 ENST00000445101.2
ring finger protein 224
chr6_-_31107127 0.06 ENST00000259845.4
psoriasis susceptibility 1 candidate 2
chr19_+_1491144 0.06 ENST00000233596.3
receptor accessory protein 6
chr19_-_4043154 0.05 ENST00000535853.1
AC016586.1
chr2_-_85641162 0.05 ENST00000447219.2
ENST00000409670.1
ENST00000409724.1
capping protein (actin filament), gelsolin-like
chr11_+_706595 0.05 ENST00000531348.1
ENST00000530636.1
EPS8-like 2
chr18_+_44497455 0.05 ENST00000592005.1
katanin p60 subunit A-like 2
chr7_+_76139925 0.05 ENST00000394849.1
uroplakin 3B
chr5_+_134303591 0.05 ENST00000282611.6
cation channel, sperm associated 3
chr14_-_23540826 0.05 ENST00000357481.2
apoptotic chromatin condensation inducer 1
chr1_-_28384598 0.04 ENST00000373864.1
eyes absent homolog 3 (Drosophila)
chr7_+_76139833 0.04 ENST00000257632.5
uroplakin 3B
chr5_+_125758813 0.04 ENST00000285689.3
ENST00000515200.1
GRAM domain containing 3
chr14_-_23540747 0.04 ENST00000555566.1
ENST00000338631.6
ENST00000557515.1
ENST00000397341.3
apoptotic chromatin condensation inducer 1
chr8_+_144821557 0.04 ENST00000534398.1
FAM83H antisense RNA 1 (head to head)
chr14_-_80677815 0.04 ENST00000557125.1
ENST00000555750.1
deiodinase, iodothyronine, type II
chr1_+_206643806 0.03 ENST00000537984.1
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr16_+_2564254 0.03 ENST00000565223.1
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr19_-_40596767 0.03 ENST00000599972.1
ENST00000450241.2
ENST00000595687.2
zinc finger protein 780A
chr7_+_76139741 0.03 ENST00000334348.3
ENST00000419923.2
ENST00000448265.3
ENST00000443097.2
uroplakin 3B
chr6_+_32121218 0.03 ENST00000414204.1
ENST00000361568.2
ENST00000395523.1
palmitoyl-protein thioesterase 2
chr5_+_125758865 0.03 ENST00000542322.1
ENST00000544396.1
GRAM domain containing 3
chr17_+_9728828 0.03 ENST00000262441.5
glucagon-like peptide 2 receptor
chr3_-_49142178 0.03 ENST00000452739.1
ENST00000414533.1
ENST00000417025.1
glutaminyl-tRNA synthetase
chr21_+_33671160 0.02 ENST00000303645.5
melanocortin 2 receptor accessory protein
chr9_+_77703414 0.02 ENST00000346234.6
osteoclast stimulating factor 1
chr14_-_80677613 0.02 ENST00000556811.1
deiodinase, iodothyronine, type II
chr5_+_125759140 0.02 ENST00000543198.1
GRAM domain containing 3
chr6_-_43027105 0.02 ENST00000230413.5
ENST00000487429.1
ENST00000489623.1
ENST00000468957.1
mitochondrial ribosomal protein L2
chr1_+_206643787 0.02 ENST00000367120.3
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr7_-_29152509 0.02 ENST00000448959.1
carboxypeptidase, vitellogenic-like
chr4_+_110736659 0.02 ENST00000394631.3
ENST00000226796.6
GAR1 ribonucleoprotein
chr9_+_130565487 0.02 ENST00000373225.3
ENST00000431857.1
folylpolyglutamate synthase
chr1_-_234667504 0.02 ENST00000421207.1
ENST00000435574.1
RP5-855F14.1
chr22_+_18560675 0.02 ENST00000329627.7
peroxisomal biogenesis factor 26
chr8_-_130799134 0.02 ENST00000276708.4
gasdermin C
chr9_+_104161123 0.02 ENST00000374861.3
ENST00000339664.2
ENST00000259395.4
zinc finger protein 189
chr3_-_49142504 0.02 ENST00000306125.6
ENST00000420147.2
glutaminyl-tRNA synthetase
chr11_+_15095108 0.01 ENST00000324229.6
ENST00000533448.1
calcitonin-related polypeptide beta
chr16_-_23568651 0.01 ENST00000563232.1
ENST00000563459.1
ENST00000449606.1
glutamyl-tRNA synthetase 2, mitochondrial
chr2_-_190446738 0.01 ENST00000427419.1
ENST00000455320.1
solute carrier family 40 (iron-regulated transporter), member 1
chr12_+_18414446 0.01 ENST00000433979.1
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
chr19_+_58038683 0.01 ENST00000240719.3
ENST00000376233.3
ENST00000594943.1
ENST00000602149.1
zinc finger protein 549
chr19_+_19496624 0.01 ENST00000494516.2
ENST00000360315.3
ENST00000252577.5
GATA zinc finger domain containing 2A
chr1_-_36863481 0.00 ENST00000315732.2
LSM10, U7 small nuclear RNA associated
chr10_+_96443204 0.00 ENST00000339022.5
cytochrome P450, family 2, subfamily C, polypeptide 18
chr4_-_69083720 0.00 ENST00000432593.3
TMPRSS11B N-terminal like
chr6_-_46889694 0.00 ENST00000283296.7
ENST00000362015.4
ENST00000456426.2
G protein-coupled receptor 116

Network of associatons between targets according to the STRING database.

First level regulatory network of GRHL1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.0 0.3 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.0 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.0 0.2 GO:1900121 negative regulation of receptor binding(GO:1900121)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0005055 laminin receptor activity(GO:0005055)
0.0 0.1 GO:0070996 melanocortin receptor binding(GO:0031779) corticotropin hormone receptor binding(GO:0031780) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782) type 5 melanocortin receptor binding(GO:0031783) type 1 melanocortin receptor binding(GO:0070996)
0.0 0.0 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384) K48-linked polyubiquitin binding(GO:0036435)
0.0 0.2 GO:0004887 thyroid hormone receptor activity(GO:0004887)