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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for GATA6

Z-value: 0.26

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Transcription factors associated with GATA6

Gene Symbol Gene ID Gene Info
GATA6
ENSG00000141448.4 GATA binding protein 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GATA6hg19_v2_chr18_+_19750894_19750980-0.712.9e-01Click!

Activity profile of GATA6 motif

Sorted Z-values of GATA6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_202298268 0.14 ENST00000440597.1
TRAK2
trafficking protein, kinesin binding 2
chr1_-_42630389 0.13 ENST00000357001.2
GUCA2A
guanylate cyclase activator 2A (guanylin)
chr19_-_39303576 0.11 ENST00000594209.1
LGALS4
lectin, galactoside-binding, soluble, 4
chr1_-_226187013 0.08 ENST00000272091.7
SDE2
SDE2 telomere maintenance homolog (S. pombe)
chr7_-_107880508 0.08 ENST00000425651.2
NRCAM
neuronal cell adhesion molecule
chr2_+_102927962 0.08 ENST00000233954.1
ENST00000393393.3
ENST00000410040.1
IL1RL1
IL18R1
interleukin 1 receptor-like 1
interleukin 18 receptor 1
chr16_+_333152 0.08 ENST00000219406.6
ENST00000404312.1
ENST00000456379.1
PDIA2
protein disulfide isomerase family A, member 2
chr15_+_49715449 0.07 ENST00000560979.1
FGF7
fibroblast growth factor 7
chr18_-_2982869 0.07 ENST00000584915.1
LPIN2
lipin 2
chr5_+_135496675 0.07 ENST00000507637.1
SMAD5
SMAD family member 5
chr5_+_157602404 0.07 ENST00000522975.1
CTC-436K13.1
CTC-436K13.1
chr14_+_100204027 0.07 ENST00000554479.1
ENST00000555145.1
EML1
echinoderm microtubule associated protein like 1
chr17_+_19314505 0.07 ENST00000461366.1
RNF112
ring finger protein 112
chr7_-_100239132 0.07 ENST00000223051.3
ENST00000431692.1
TFR2
transferrin receptor 2
chr2_-_44065889 0.06 ENST00000543989.1
ENST00000405322.1
ABCG5
ATP-binding cassette, sub-family G (WHITE), member 5
chr10_+_71075516 0.06 ENST00000436817.1
HK1
hexokinase 1
chr5_+_131892815 0.05 ENST00000453394.1
RAD50
RAD50 homolog (S. cerevisiae)
chr2_+_109237717 0.05 ENST00000409441.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr12_-_122879969 0.05 ENST00000540304.1
CLIP1
CAP-GLY domain containing linker protein 1
chr12_-_56221330 0.05 ENST00000546837.1
RP11-762I7.5
Uncharacterized protein
chr10_-_21186144 0.05 ENST00000377119.1
NEBL
nebulette
chr11_-_10920838 0.05 ENST00000503469.2
CTD-2003C8.2
CTD-2003C8.2
chr7_+_155090271 0.05 ENST00000476756.1
INSIG1
insulin induced gene 1
chr6_+_12290586 0.05 ENST00000379375.5
EDN1
endothelin 1
chr15_+_49715293 0.04 ENST00000267843.4
ENST00000560270.1
FGF7
fibroblast growth factor 7
chr14_-_38036271 0.04 ENST00000556024.1
RP11-356O9.2
RP11-356O9.2
chr10_+_71075552 0.04 ENST00000298649.3
HK1
hexokinase 1
chr15_-_64126084 0.04 ENST00000560316.1
ENST00000443617.2
ENST00000560462.1
ENST00000558532.1
ENST00000561400.1
HERC1
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
chr14_-_23284675 0.04 ENST00000555959.1
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr17_+_4675175 0.04 ENST00000270560.3
TM4SF5
transmembrane 4 L six family member 5
chr14_+_53173910 0.04 ENST00000606149.1
ENST00000555339.1
ENST00000556813.1
PSMC6
proteasome (prosome, macropain) 26S subunit, ATPase, 6
chr5_+_131892603 0.04 ENST00000378823.3
ENST00000265335.6
RAD50
RAD50 homolog (S. cerevisiae)
chr17_-_38938786 0.03 ENST00000301656.3
KRT27
keratin 27
chr15_+_81391740 0.03 ENST00000561216.1
C15orf26
chromosome 15 open reading frame 26
chr14_-_38028689 0.03 ENST00000553425.1
RP11-356O9.2
RP11-356O9.2
chr6_-_30128657 0.03 ENST00000449742.2
ENST00000376704.3
TRIM10
tripartite motif containing 10
chr9_-_114937465 0.03 ENST00000355396.3
SUSD1
sushi domain containing 1
chr12_+_4430371 0.03 ENST00000179259.4
C12orf5
chromosome 12 open reading frame 5
chr9_-_114937543 0.03 ENST00000374264.2
ENST00000374263.3
SUSD1
sushi domain containing 1
chr6_+_148593425 0.03 ENST00000367469.1
SASH1
SAM and SH3 domain containing 1
chr2_+_220495800 0.03 ENST00000413743.1
SLC4A3
solute carrier family 4 (anion exchanger), member 3
chr20_+_54967663 0.03 ENST00000452950.1
CSTF1
cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
chr20_-_60294804 0.03 ENST00000317652.1
RP11-429E11.3
Uncharacterized protein
chr20_+_54967409 0.02 ENST00000415828.1
ENST00000217109.4
ENST00000428552.1
CSTF1
cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
chr7_+_128379346 0.02 ENST00000535011.2
ENST00000542996.2
ENST00000535623.1
ENST00000538546.1
ENST00000249364.4
ENST00000449187.2
CALU
calumenin
chr14_+_105952648 0.02 ENST00000330233.7
CRIP1
cysteine-rich protein 1 (intestinal)
chr11_-_116708302 0.02 ENST00000375320.1
ENST00000359492.2
ENST00000375329.2
ENST00000375323.1
APOA1
apolipoprotein A-I
chr15_+_59279851 0.02 ENST00000348370.4
ENST00000434298.1
ENST00000559160.1
RNF111
ring finger protein 111
chr9_-_117692697 0.02 ENST00000223795.2
TNFSF8
tumor necrosis factor (ligand) superfamily, member 8
chr12_+_111843749 0.02 ENST00000341259.2
SH2B3
SH2B adaptor protein 3
chr1_-_24469602 0.02 ENST00000270800.1
IL22RA1
interleukin 22 receptor, alpha 1
chr10_+_118305435 0.02 ENST00000369221.2
PNLIP
pancreatic lipase
chr14_-_21945057 0.02 ENST00000397762.1
RAB2B
RAB2B, member RAS oncogene family
chr17_+_72920370 0.02 ENST00000331427.4
OTOP2
otopetrin 2
chr14_+_50999744 0.02 ENST00000441560.2
ATL1
atlastin GTPase 1
chr1_+_171217622 0.02 ENST00000433267.1
ENST00000367750.3
FMO1
flavin containing monooxygenase 1
chr18_-_28742813 0.02 ENST00000257197.3
ENST00000257198.5
DSC1
desmocollin 1
chr11_+_118958689 0.02 ENST00000535253.1
ENST00000392841.1
HMBS
hydroxymethylbilane synthase
chr17_-_62084241 0.02 ENST00000449662.2
ICAM2
intercellular adhesion molecule 2
chr9_-_114937676 0.02 ENST00000374270.3
SUSD1
sushi domain containing 1
chr4_-_103266219 0.01 ENST00000394833.2
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr19_-_51523275 0.01 ENST00000309958.3
KLK10
kallikrein-related peptidase 10
chr14_+_53173890 0.01 ENST00000445930.2
PSMC6
proteasome (prosome, macropain) 26S subunit, ATPase, 6
chr16_+_202686 0.01 ENST00000252951.2
HBZ
hemoglobin, zeta
chr16_+_71560023 0.01 ENST00000572450.1
CHST4
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
chr5_-_33984741 0.01 ENST00000382102.3
ENST00000509381.1
ENST00000342059.3
ENST00000345083.5
SLC45A2
solute carrier family 45, member 2
chrX_+_37865804 0.01 ENST00000297875.2
ENST00000357972.5
SYTL5
synaptotagmin-like 5
chr17_-_29645836 0.01 ENST00000578584.1
CTD-2370N5.3
CTD-2370N5.3
chr11_-_1036706 0.01 ENST00000421673.2
MUC6
mucin 6, oligomeric mucus/gel-forming
chr12_+_53818855 0.01 ENST00000550839.1
AMHR2
anti-Mullerian hormone receptor, type II
chr16_+_71560154 0.01 ENST00000539698.3
CHST4
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
chr12_-_54689532 0.01 ENST00000540264.2
ENST00000312156.4
NFE2
nuclear factor, erythroid 2
chr1_-_205912577 0.01 ENST00000367135.3
ENST00000367134.2
SLC26A9
solute carrier family 26 (anion exchanger), member 9
chr10_+_24755416 0.01 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
KIAA1217
chr20_-_54967187 0.01 ENST00000422322.1
ENST00000371356.2
ENST00000451915.1
ENST00000347343.2
ENST00000395911.1
ENST00000395907.1
ENST00000441357.1
ENST00000456249.1
ENST00000420474.1
ENST00000395909.4
ENST00000395914.1
ENST00000312783.6
ENST00000395915.3
ENST00000395913.3
AURKA
aurora kinase A
chr17_+_72920698 0.01 ENST00000580223.1
OTOP2
otopetrin 2
chr4_+_166794383 0.01 ENST00000061240.2
ENST00000507499.1
TLL1
tolloid-like 1
chr2_-_152830441 0.01 ENST00000534999.1
ENST00000397327.2
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr8_+_21823726 0.01 ENST00000433566.4
XPO7
exportin 7
chr5_-_33984786 0.01 ENST00000296589.4
SLC45A2
solute carrier family 45, member 2
chr7_+_150690857 0.01 ENST00000484524.1
ENST00000467517.1
NOS3
nitric oxide synthase 3 (endothelial cell)
chrX_-_10851762 0.01 ENST00000380785.1
ENST00000380787.1
MID1
midline 1 (Opitz/BBB syndrome)
chr11_-_10920714 0.01 ENST00000533941.1
CTD-2003C8.2
CTD-2003C8.2
chr4_-_186697044 0.00 ENST00000437304.2
SORBS2
sorbin and SH3 domain containing 2
chr18_-_45663666 0.00 ENST00000535628.2
ZBTB7C
zinc finger and BTB domain containing 7C
chr12_+_109785708 0.00 ENST00000310903.5
MYO1H
myosin IH
chr17_+_38673270 0.00 ENST00000578280.1
RP5-1028K7.2
RP5-1028K7.2
chr1_-_167487808 0.00 ENST00000392122.3
CD247
CD247 molecule
chr16_+_4475806 0.00 ENST00000262375.6
ENST00000355296.4
ENST00000431375.2
ENST00000574895.1
DNAJA3
DnaJ (Hsp40) homolog, subfamily A, member 3
chr5_-_141703713 0.00 ENST00000511815.1
SPRY4
sprouty homolog 4 (Drosophila)
chr3_+_69812701 0.00 ENST00000472437.1
MITF
microphthalmia-associated transcription factor
chr19_-_51522955 0.00 ENST00000358789.3
KLK10
kallikrein-related peptidase 10
chr16_+_67022476 0.00 ENST00000540947.2
CES4A
carboxylesterase 4A
chr16_+_53920795 0.00 ENST00000431610.2
ENST00000460382.1
FTO
fat mass and obesity associated
chr1_-_167487758 0.00 ENST00000362089.5
CD247
CD247 molecule

Network of associatons between targets according to the STRING database.

First level regulatory network of GATA6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0098972 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.0 0.1 GO:0060437 lung growth(GO:0060437)
0.0 0.1 GO:1904729 regulation of intestinal cholesterol absorption(GO:0030300) regulation of intestinal lipid absorption(GO:1904729)
0.0 0.0 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.0 GO:0060584 nitric oxide transport(GO:0030185) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585) positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.0 0.1 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:0097460 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.0 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0002113 interleukin-33 binding(GO:0002113)
0.0 0.1 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.1 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 0.0 GO:0031705 bombesin receptor binding(GO:0031705)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.1 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)