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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)
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Results for FOXL1
Z-value: 0.75
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Transcription factors associated with FOXL1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| FOXL1 | hg19_v2_chr16_+_86612112_86612123 | -0.73 | 2.7e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr1_-_238108575 Show fit | 0.31 |
ENST00000604646.1
|
MT-RNR2-like 11 (pseudogene) |
|
| chr1_+_174670143 Show fit | 0.29 |
ENST00000367687.1
ENST00000347255.2 |
RAB GTPase activating protein 1-like |
|
| chr6_+_37012607 Show fit | 0.28 |
ENST00000423336.1
|
cytochrome c oxidase subunit VIa polypeptide 1 pseudogene 2 |
|
| chr21_+_35107346 Show fit | 0.26 |
ENST00000456489.1
|
intersectin 1 (SH3 domain protein) |
|
| chr15_-_80263506 Show fit | 0.26 |
ENST00000335661.6
|
BCL2-related protein A1 |
|
| chr8_+_52730143 Show fit | 0.25 |
ENST00000415643.1
|
Uncharacterized protein |
|
| chr18_+_68002675 Show fit | 0.24 |
ENST00000584919.1
|
Uncharacterized protein |
|
| chr5_-_145483932 Show fit | 0.23 |
ENST00000311450.4
|
PLAC8-like 1 |
|
| chr9_-_125240235 Show fit | 0.23 |
ENST00000259357.2
|
olfactory receptor, family 1, subfamily J, member 1 |
|
| chr19_+_9203855 Show fit | 0.23 |
ENST00000429566.3
|
olfactory receptor, family 1, subfamily M, member 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of FOXL1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.0 | GO:0050911 | detection of chemical stimulus involved in sensory perception of smell(GO:0050911) |
| 0.1 | 0.3 | GO:0098507 | polynucleotide 5' dephosphorylation(GO:0098507) |
| 0.0 | 0.3 | GO:0040015 | negative regulation of multicellular organism growth(GO:0040015) |
| 0.1 | 0.2 | GO:0031247 | actin rod assembly(GO:0031247) |
| 0.1 | 0.2 | GO:0060164 | negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of mechanoreceptor differentiation(GO:0045632) regulation of timing of neuron differentiation(GO:0060164) negative regulation of inner ear receptor cell differentiation(GO:2000981) |
| 0.1 | 0.2 | GO:0051086 | chaperone mediated protein folding independent of cofactor(GO:0051086) |
| 0.0 | 0.2 | GO:0002725 | negative regulation of T cell cytokine production(GO:0002725) |
| 0.0 | 0.2 | GO:0071042 | nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047) |
| 0.0 | 0.2 | GO:0042483 | negative regulation of odontogenesis(GO:0042483) negative regulation of tooth mineralization(GO:0070171) |
| 0.0 | 0.2 | GO:0051083 | 'de novo' cotranslational protein folding(GO:0051083) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 0.0 | 0.3 | GO:0071682 | endocytic vesicle lumen(GO:0071682) |
| 0.0 | 0.2 | GO:0034680 | integrin alpha10-beta1 complex(GO:0034680) |
| 0.0 | 0.2 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
| 0.0 | 0.2 | GO:0072669 | tRNA-splicing ligase complex(GO:0072669) |
| 0.0 | 0.2 | GO:0036128 | CatSper complex(GO:0036128) |
| 0.0 | 0.2 | GO:0044233 | ER-mitochondrion membrane contact site(GO:0044233) |
| 0.0 | 0.2 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
| 0.0 | 0.1 | GO:0002079 | inner acrosomal membrane(GO:0002079) |
| 0.0 | 0.1 | GO:0005595 | collagen type XII trimer(GO:0005595) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.0 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.1 | 0.3 | GO:0004651 | polynucleotide 5'-phosphatase activity(GO:0004651) |
| 0.0 | 0.3 | GO:0046790 | virion binding(GO:0046790) |
| 0.0 | 0.3 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.1 | 0.2 | GO:0060001 | minus-end directed microfilament motor activity(GO:0060001) |
| 0.0 | 0.2 | GO:0098639 | collagen binding involved in cell-matrix adhesion(GO:0098639) |
| 0.0 | 0.2 | GO:0016413 | O-acetyltransferase activity(GO:0016413) |
| 0.0 | 0.2 | GO:0004322 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
| 0.0 | 0.2 | GO:0004771 | sterol esterase activity(GO:0004771) |
| 0.0 | 0.2 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | ST TYPE I INTERFERON PATHWAY | Type I Interferon (alpha/beta IFN) Pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.8 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |
| 0.0 | 0.4 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
| 0.0 | 0.3 | REACTOME REGULATION OF IFNA SIGNALING | Genes involved in Regulation of IFNA signaling |
| 0.0 | 0.2 | REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR | Genes involved in Trafficking and processing of endosomal TLR |