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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for FOXA3_FOXC2

Z-value: 0.38

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Transcription factors associated with FOXA3_FOXC2

Gene Symbol Gene ID Gene Info
ENSG00000170608.2 forkhead box A3
ENSG00000176692.4 forkhead box C2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXA3hg19_v2_chr19_+_46367518_46367567-0.613.9e-01Click!
FOXC2hg19_v2_chr16_+_86600857_866009210.109.0e-01Click!

Activity profile of FOXA3_FOXC2 motif

Sorted Z-values of FOXA3_FOXC2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_106415457 0.16 ENST00000490162.2
ENST00000470135.1
RP5-884M6.1
chr1_-_207095324 0.12 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
Fas apoptotic inhibitory molecule 3
chr2_+_179318295 0.12 ENST00000442710.1
deafness, autosomal recessive 59
chr2_+_58655461 0.11 ENST00000429095.1
ENST00000429664.1
ENST00000452840.1
long intergenic non-protein coding RNA 1122
chr1_-_149859466 0.11 ENST00000331128.3
histone cluster 2, H2ab
chr12_-_12714006 0.11 ENST00000541207.1
dual specificity phosphatase 16
chr1_-_1356628 0.10 ENST00000442470.1
ENST00000537107.1
ankyrin repeat domain 65
chr1_-_1356719 0.10 ENST00000520296.1
ankyrin repeat domain 65
chr12_-_12714025 0.10 ENST00000539940.1
dual specificity phosphatase 16
chr4_+_76871883 0.10 ENST00000599764.1
Uncharacterized protein
chr2_+_109223595 0.09 ENST00000410093.1
LIM and senescent cell antigen-like domains 1
chr2_-_208030295 0.09 ENST00000458272.1
Kruppel-like factor 7 (ubiquitous)
chr10_+_124739964 0.09 ENST00000406217.2
phosphoseryl-tRNA kinase
chr5_+_95998746 0.08 ENST00000508608.1
calpastatin
chr16_-_87970122 0.08 ENST00000309893.2
carbonic anhydrase VA, mitochondrial
chr2_-_87248975 0.08 ENST00000409310.2
ENST00000355705.3
plasminogen-like B1
chr17_-_19290483 0.08 ENST00000395592.2
ENST00000299610.4
microfibrillar-associated protein 4
chr5_-_137674000 0.07 ENST00000510119.1
ENST00000513970.1
cell division cycle 25C
chr11_+_65851443 0.07 ENST00000533756.1
phosphofurin acidic cluster sorting protein 1
chr12_+_96588279 0.07 ENST00000552142.1
ELK3, ETS-domain protein (SRF accessory protein 2)
chr11_+_8040739 0.07 ENST00000534099.1
tubby bipartite transcription factor
chr10_-_128210005 0.07 ENST00000284694.7
ENST00000454341.1
ENST00000432642.1
ENST00000392694.1
chromosome 10 open reading frame 90
chr2_+_196521903 0.06 ENST00000541054.1
solute carrier family 39 (zinc transporter), member 10
chr7_+_151791074 0.06 ENST00000447796.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr9_-_20382446 0.06 ENST00000380321.1
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr8_+_142264664 0.06 ENST00000518520.1
Uncharacterized protein
chr6_-_13621126 0.06 ENST00000600057.1
Uncharacterized protein
chr2_+_196521845 0.06 ENST00000359634.5
ENST00000412905.1
solute carrier family 39 (zinc transporter), member 10
chr7_+_151791037 0.06 ENST00000419245.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr2_-_175711924 0.06 ENST00000444573.1
chimerin 1
chr6_+_37897735 0.06 ENST00000373389.5
zinc finger, AN1-type domain 3
chr3_-_193096600 0.06 ENST00000446087.1
ENST00000342358.4
ATPase type 13A5
chr17_-_36358166 0.05 ENST00000537432.1
TBC1 domain family, member 3
chr12_+_59989918 0.05 ENST00000547379.1
ENST00000549465.1
solute carrier family 16 (monocarboxylate transporter), member 7
chr1_+_152486950 0.05 ENST00000368790.3
cysteine-rich C-terminal 1
chr1_+_239882842 0.05 ENST00000448020.1
cholinergic receptor, muscarinic 3
chr6_+_26251835 0.05 ENST00000356350.2
histone cluster 1, H2bh
chr2_+_66918558 0.05 ENST00000435389.1
ENST00000428590.1
ENST00000412944.1
AC007392.3
chr2_-_192711968 0.05 ENST00000304141.4
serum deprivation response
chr15_+_63188009 0.05 ENST00000557900.1
RP11-1069G10.2
chr10_-_118032697 0.05 ENST00000439649.3
GDNF family receptor alpha 1
chr2_+_136343904 0.05 ENST00000436436.1
R3H domain containing 1
chr2_-_175711978 0.05 ENST00000409089.2
chimerin 1
chr15_+_76016293 0.05 ENST00000332145.2
outer dense fiber of sperm tails 3-like 1
chr5_+_169011033 0.04 ENST00000513795.1
spindle apparatus coiled-coil protein 1
chr2_-_46844242 0.04 ENST00000281382.6
phosphatidylinositol glycan anchor biosynthesis, class F
chr9_+_129097520 0.04 ENST00000436593.3
multivesicular body subunit 12B
chr18_-_52626622 0.04 ENST00000591504.1
coiled-coil domain containing 68
chr5_+_74807886 0.04 ENST00000514296.1
polymerase (DNA directed) kappa
chr1_+_150488205 0.04 ENST00000416894.1
long intergenic non-protein coding RNA 568
chr14_-_31926623 0.04 ENST00000356180.4
D-tyrosyl-tRNA deacylase 2 (putative)
chr11_-_72852320 0.04 ENST00000422375.1
FCH and double SH3 domains 2
chr7_+_151038850 0.04 ENST00000355851.4
ENST00000566856.1
ENST00000470229.1
negative regulator of ubiquitin-like proteins 1
chr15_-_59041768 0.04 ENST00000402627.1
ENST00000396140.2
ENST00000559053.1
ENST00000561288.1
ADAM metallopeptidase domain 10
chr12_+_120740119 0.04 ENST00000536460.1
ENST00000202967.4
sirtuin 4
chr17_-_41322332 0.04 ENST00000590740.1
RP11-242D8.1
chr4_+_75174204 0.04 ENST00000332112.4
ENST00000514968.1
ENST00000503098.1
ENST00000502358.1
ENST00000509145.1
ENST00000505212.1
epithelial mitogen
chr2_-_165424973 0.04 ENST00000543549.1
growth factor receptor-bound protein 14
chr18_-_25616519 0.04 ENST00000399380.3
cadherin 2, type 1, N-cadherin (neuronal)
chr17_+_37030127 0.04 ENST00000419929.1
LIM and SH3 protein 1
chr2_+_169658928 0.04 ENST00000317647.7
ENST00000445023.2
nitric oxide synthase trafficking
chr3_+_159570722 0.04 ENST00000482804.1
schwannomin interacting protein 1
chr7_+_134576317 0.03 ENST00000424922.1
ENST00000495522.1
caldesmon 1
chr13_+_95364963 0.03 ENST00000438290.2
SOX21 antisense RNA 1 (head to head)
chr20_+_9146969 0.03 ENST00000416836.1
phospholipase C, beta 4
chr5_+_133859996 0.03 ENST00000512386.1
jade family PHD finger 2
chr2_+_169659121 0.03 ENST00000397206.2
ENST00000397209.2
ENST00000421711.2
nitric oxide synthase trafficking
chr17_-_77967433 0.03 ENST00000571872.1
TBC1 domain family, member 16
chr4_-_170679024 0.03 ENST00000393381.2
chromosome 4 open reading frame 27
chr2_-_175711133 0.03 ENST00000409597.1
ENST00000413882.1
chimerin 1
chr8_+_104384616 0.03 ENST00000520337.1
collagen triple helix repeat containing 1
chr12_-_48099754 0.03 ENST00000380650.4
RNA polymerase II associated protein 3
chr16_-_15474904 0.03 ENST00000534094.1
nuclear pore complex interacting protein family, member A5
chr12_-_15865844 0.03 ENST00000543612.1
epidermal growth factor receptor pathway substrate 8
chr1_+_246729815 0.03 ENST00000366511.1
consortin, connexin sorting protein
chr7_+_95115210 0.03 ENST00000428113.1
ENST00000325885.5
ankyrin repeat and SOCS box containing 4
chr5_+_147774275 0.03 ENST00000513826.1
F-box protein 38
chr20_+_9049742 0.03 ENST00000437503.1
phospholipase C, beta 4
chr3_+_155588375 0.03 ENST00000295920.7
guanine monphosphate synthase
chr3_+_136649311 0.03 ENST00000469404.1
ENST00000467911.1
NCK adaptor protein 1
chr3_-_196910721 0.03 ENST00000443183.1
discs, large homolog 1 (Drosophila)
chr3_-_107941230 0.03 ENST00000264538.3
intraflagellar transport 57 homolog (Chlamydomonas)
chr3_-_105588231 0.03 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr12_-_21927736 0.03 ENST00000240662.2
potassium inwardly-rectifying channel, subfamily J, member 8
chr1_-_150669604 0.03 ENST00000427665.1
ENST00000540514.1
golgi phosphoprotein 3-like
chr2_+_175260514 0.03 ENST00000424069.1
ENST00000427038.1
secernin 3
chr5_+_74807581 0.03 ENST00000241436.4
ENST00000352007.5
polymerase (DNA directed) kappa
chr11_-_72070206 0.03 ENST00000544382.1
ClpB caseinolytic peptidase B homolog (E. coli)
chr18_+_21033239 0.03 ENST00000581585.1
ENST00000577501.1
RIO kinase 3
chr3_-_196910477 0.03 ENST00000447466.1
discs, large homolog 1 (Drosophila)
chr3_+_69985734 0.03 ENST00000314557.6
ENST00000394351.3
microphthalmia-associated transcription factor
chr12_-_53207842 0.03 ENST00000458244.2
keratin 4
chr13_-_99667960 0.03 ENST00000448493.2
dedicator of cytokinesis 9
chr12_+_27849378 0.03 ENST00000310791.2
RAB15 effector protein
chr1_+_104159999 0.03 ENST00000414303.2
ENST00000423678.1
amylase, alpha 2A (pancreatic)
chr15_+_80364901 0.03 ENST00000560228.1
ENST00000559835.1
ENST00000559775.1
ENST00000558688.1
ENST00000560392.1
ENST00000560976.1
ENST00000558272.1
ENST00000558390.1
zinc finger, AN1-type domain 6
chr3_+_132316081 0.03 ENST00000249887.2
atypical chemokine receptor 4
chr3_+_57882024 0.03 ENST00000494088.1
sarcolemma associated protein
chr12_-_106480587 0.03 ENST00000548902.1
NUAK family, SNF1-like kinase, 1
chr13_+_73629107 0.03 ENST00000539231.1
Kruppel-like factor 5 (intestinal)
chr7_+_134464376 0.03 ENST00000454108.1
ENST00000361675.2
caldesmon 1
chr15_+_59664884 0.03 ENST00000558348.1
family with sequence similarity 81, member A
chr3_-_71294304 0.03 ENST00000498215.1
forkhead box P1
chr14_+_20811766 0.03 ENST00000250416.5
ENST00000527915.1
poly (ADP-ribose) polymerase 2
chr16_-_3350614 0.03 ENST00000268674.2
tigger transposable element derived 7
chr2_-_65593784 0.03 ENST00000443619.2
sprouty-related, EVH1 domain containing 2
chr2_+_68592305 0.03 ENST00000234313.7
pleckstrin
chr7_+_26438187 0.03 ENST00000439120.1
ENST00000430548.1
ENST00000421862.1
ENST00000449537.1
ENST00000420774.1
ENST00000418758.2
AC004540.5
chr1_-_154150651 0.03 ENST00000302206.5
tropomyosin 3
chr7_-_117512264 0.02 ENST00000454375.1
cortactin binding protein 2
chr16_-_48281305 0.02 ENST00000356608.2
ATP-binding cassette, sub-family C (CFTR/MRP), member 11
chr8_-_80993010 0.02 ENST00000537855.1
ENST00000520527.1
ENST00000517427.1
ENST00000448733.2
ENST00000379097.3
tumor protein D52
chr1_+_246729724 0.02 ENST00000366513.4
ENST00000366512.3
consortin, connexin sorting protein
chr4_-_152149033 0.02 ENST00000514152.1
SH3 domain containing 19
chr14_+_20215587 0.02 ENST00000331723.1
olfactory receptor, family 4, subfamily Q, member 3
chr22_+_21128167 0.02 ENST00000215727.5
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr8_+_21777159 0.02 ENST00000434536.1
ENST00000252512.9
exportin 7
chr17_-_37764128 0.02 ENST00000302584.4
neuronal differentiation 2
chr2_+_175260451 0.02 ENST00000458563.1
ENST00000409673.3
ENST00000272732.6
ENST00000435964.1
secernin 3
chr10_-_126849588 0.02 ENST00000411419.2
C-terminal binding protein 2
chr1_+_61547405 0.02 ENST00000371189.4
nuclear factor I/A
chr1_-_169555709 0.02 ENST00000546081.1
coagulation factor V (proaccelerin, labile factor)
chr1_-_43855444 0.02 ENST00000372455.4
mediator complex subunit 8
chr1_-_149459549 0.02 ENST00000369175.3
family with sequence similarity 72, member C
chr8_+_19171128 0.02 ENST00000265807.3
SH2 domain containing 4A
chr10_-_118032979 0.02 ENST00000355422.6
GDNF family receptor alpha 1
chr4_+_86396321 0.02 ENST00000503995.1
Rho GTPase activating protein 24
chr8_+_97597148 0.02 ENST00000521590.1
syndecan 2
chr5_+_61708582 0.02 ENST00000325324.6
importin 11
chr11_-_116708302 0.02 ENST00000375320.1
ENST00000359492.2
ENST00000375329.2
ENST00000375323.1
apolipoprotein A-I
chr12_-_71551652 0.02 ENST00000546561.1
tetraspanin 8
chr17_-_39684550 0.02 ENST00000455635.1
ENST00000361566.3
keratin 19
chr14_+_58711539 0.02 ENST00000216455.4
ENST00000412908.2
ENST00000557508.1
proteasome (prosome, macropain) subunit, alpha type, 3
chr15_+_69854027 0.02 ENST00000498938.2
RP11-279F6.1
chr1_+_114471972 0.02 ENST00000369559.4
ENST00000369554.2
homeodomain interacting protein kinase 1
chr3_-_139195350 0.02 ENST00000232217.2
retinol binding protein 2, cellular
chr5_+_140710061 0.02 ENST00000517417.1
ENST00000378105.3
protocadherin gamma subfamily A, 1
chr10_+_81466084 0.02 ENST00000342531.2
NUT family member 2B
chr12_-_48099773 0.02 ENST00000432584.3
ENST00000005386.3
RNA polymerase II associated protein 3
chr14_-_24664540 0.02 ENST00000530563.1
ENST00000528895.1
ENST00000528669.1
ENST00000532632.1
transmembrane 9 superfamily member 1
chr10_-_21186144 0.02 ENST00000377119.1
nebulette
chr14_+_20811722 0.02 ENST00000429687.3
poly (ADP-ribose) polymerase 2
chr3_+_148447887 0.02 ENST00000475347.1
ENST00000474935.1
ENST00000461609.1
angiotensin II receptor, type 1
chr4_+_71588372 0.02 ENST00000536664.1
RUN and FYVE domain containing 3
chr14_+_56127989 0.02 ENST00000555573.1
kinectin 1 (kinesin receptor)
chr21_-_36259445 0.02 ENST00000399240.1
runt-related transcription factor 1
chr5_+_32531893 0.02 ENST00000512913.1
SUB1 homolog (S. cerevisiae)
chr7_-_107643674 0.02 ENST00000222399.6
laminin, beta 1
chr4_+_169013666 0.02 ENST00000359299.3
annexin A10
chr2_-_21266935 0.02 ENST00000233242.1
apolipoprotein B
chr9_+_116343192 0.02 ENST00000471324.2
regulator of G-protein signaling 3
chr1_-_177939041 0.02 ENST00000308284.6
SEC16 homolog B (S. cerevisiae)
chr2_+_171640291 0.02 ENST00000409885.1
glutamate-rich 2
chrX_-_47863348 0.02 ENST00000376943.3
ENST00000396965.1
ENST00000305127.6
zinc finger protein 182
chr7_+_134430212 0.02 ENST00000436461.2
caldesmon 1
chr6_-_131211534 0.02 ENST00000456097.2
erythrocyte membrane protein band 4.1-like 2
chr4_-_21950356 0.02 ENST00000447367.2
ENST00000382152.2
Kv channel interacting protein 4
chr15_+_71185148 0.02 ENST00000443425.2
ENST00000560755.1
leucine rich repeat containing 49
chr8_+_101349823 0.02 ENST00000519566.1
KB-1991G8.1
chr4_+_79567362 0.02 ENST00000512322.1
long intergenic non-protein coding RNA 1094
chr7_+_77469439 0.02 ENST00000450574.1
ENST00000416283.2
ENST00000248550.7
putative homeodomain transcription factor 2
chr16_+_4666475 0.02 ENST00000591895.1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr20_+_9049682 0.02 ENST00000334005.3
ENST00000378473.3
phospholipase C, beta 4
chr10_-_31288398 0.02 ENST00000538351.2
zinc finger protein 438
chr14_+_56127960 0.02 ENST00000553624.1
kinectin 1 (kinesin receptor)
chr3_+_130569592 0.02 ENST00000533801.2
ATPase, Ca++ transporting, type 2C, member 1
chr2_-_161056762 0.02 ENST00000428609.2
ENST00000409967.2
integrin, beta 6
chr6_+_21666633 0.02 ENST00000606851.1
cancer susceptibility candidate 15 (non-protein coding)
chr3_-_116163830 0.02 ENST00000333617.4
limbic system-associated membrane protein
chr4_+_148653206 0.02 ENST00000336498.3
Rho GTPase activating protein 10
chr3_+_141106643 0.02 ENST00000514251.1
zinc finger and BTB domain containing 38
chr2_-_21266816 0.02 ENST00000399256.4
apolipoprotein B
chr15_+_59665194 0.02 ENST00000560394.1
family with sequence similarity 81, member A
chr5_-_58571935 0.02 ENST00000503258.1
phosphodiesterase 4D, cAMP-specific
chr19_+_15160130 0.02 ENST00000427043.3
caspase 14, apoptosis-related cysteine peptidase
chr1_+_114471809 0.02 ENST00000426820.2
homeodomain interacting protein kinase 1
chr2_+_136343820 0.02 ENST00000410054.1
R3H domain containing 1
chr4_+_146403912 0.02 ENST00000507367.1
ENST00000394092.2
ENST00000515385.1
SMAD family member 1
chr15_+_69857515 0.02 ENST00000559477.1
RP11-279F6.1
chr17_-_6947225 0.02 ENST00000574600.1
ENST00000308009.1
ENST00000447225.1
solute carrier family 16, member 11
chr1_+_12806141 0.02 ENST00000288048.5
chromosome 1 open reading frame 158
chr2_+_28974489 0.02 ENST00000455580.1
protein phosphatase 1, catalytic subunit, beta isozyme
chr3_+_142315225 0.02 ENST00000457734.2
ENST00000483373.1
ENST00000475296.1
ENST00000495744.1
ENST00000476044.1
ENST00000461644.1
plastin 1
chr7_+_134464414 0.02 ENST00000361901.2
caldesmon 1
chr5_+_95998714 0.02 ENST00000506811.1
ENST00000514055.1
calpastatin
chr3_+_142315294 0.02 ENST00000464320.1
plastin 1
chr5_+_65222500 0.02 ENST00000511297.1
ENST00000506030.1
erbb2 interacting protein
chr2_+_88047606 0.02 ENST00000359481.4
plasminogen-like B2
chr5_+_156712372 0.02 ENST00000541131.1
cytoplasmic FMR1 interacting protein 2
chr18_+_21032781 0.02 ENST00000339486.3
RIO kinase 3
chr10_+_95848824 0.02 ENST00000371385.3
ENST00000371375.1
phospholipase C, epsilon 1
chr7_+_112063192 0.02 ENST00000005558.4
interferon-related developmental regulator 1
chr7_+_134576151 0.02 ENST00000393118.2
caldesmon 1
chr6_-_112575758 0.02 ENST00000431543.2
ENST00000453937.2
ENST00000368638.4
ENST00000389463.4
laminin, alpha 4
chr11_-_102401469 0.02 ENST00000260227.4
matrix metallopeptidase 7 (matrilysin, uterine)
chr5_+_61874562 0.02 ENST00000334994.5
ENST00000409534.1
leucine rich repeat containing 70
importin 11
chr6_-_24666819 0.02 ENST00000341060.3
tyrosyl-DNA phosphodiesterase 2
chr1_+_179851893 0.02 ENST00000531630.2
torsin A interacting protein 1
chr6_+_10528560 0.02 ENST00000379597.3
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr15_+_49462397 0.02 ENST00000396509.2
galactokinase 2

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXA3_FOXC2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0045209 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.0 0.1 GO:1903613 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.0 0.0 GO:1903217 regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.0 0.1 GO:0097056 selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.0 0.0 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.0 0.1 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.0 0.0 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.1 GO:0034371 chylomicron remodeling(GO:0034371)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.0 GO:0034685 integrin alphav-beta6 complex(GO:0034685)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.0 GO:0051500 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.0 0.0 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.0 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)