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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for FOSL2_SMARCC1

Z-value: 1.49

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Transcription factors associated with FOSL2_SMARCC1

Gene Symbol Gene ID Gene Info
FOSL2
ENSG00000075426.7 FOS like 2, AP-1 transcription factor subunit
SMARCC1
ENSG00000173473.6 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SMARCC1hg19_v2_chr3_-_47823298_478234230.991.2e-02Click!
FOSL2hg19_v2_chr2_+_28615669_286157330.991.3e-02Click!

Activity profile of FOSL2_SMARCC1 motif

Sorted Z-values of FOSL2_SMARCC1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_46009837 2.72 ENST00000589627.1
VASP
vasodilator-stimulated phosphoprotein
chr11_+_393428 2.36 ENST00000533249.1
ENST00000527442.1
PKP3
plakophilin 3
chr5_-_176923803 2.00 ENST00000506161.1
PDLIM7
PDZ and LIM domain 7 (enigma)
chr11_+_394145 1.89 ENST00000528036.1
PKP3
plakophilin 3
chr11_-_67141640 1.77 ENST00000533438.1
CLCF1
cardiotrophin-like cytokine factor 1
chr5_+_149877440 1.31 ENST00000518299.1
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr11_-_62323702 1.19 ENST00000530285.1
AHNAK
AHNAK nucleoprotein
chr17_+_7123207 1.16 ENST00000584103.1
ENST00000579886.2
ACADVL
acyl-CoA dehydrogenase, very long chain
chr12_+_48152774 1.15 ENST00000549243.1
SLC48A1
solute carrier family 48 (heme transporter), member 1
chr5_-_176923846 1.07 ENST00000506537.1
PDLIM7
PDZ and LIM domain 7 (enigma)
chr14_-_75083313 1.07 ENST00000556652.1
ENST00000555313.1
CTD-2207P18.2
CTD-2207P18.2
chr5_+_175288631 1.07 ENST00000509837.1
CPLX2
complexin 2
chr1_-_153935791 1.04 ENST00000429040.1
SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr5_+_150020240 0.94 ENST00000519664.1
SYNPO
synaptopodin
chr5_+_150020214 0.92 ENST00000307662.4
SYNPO
synaptopodin
chr11_+_35639735 0.92 ENST00000317811.4
FJX1
four jointed box 1 (Drosophila)
chr3_-_48632593 0.90 ENST00000454817.1
ENST00000328333.8
COL7A1
collagen, type VII, alpha 1
chr1_-_153521714 0.82 ENST00000368713.3
S100A3
S100 calcium binding protein A3
chr3_-_48601206 0.80 ENST00000273610.3
UCN2
urocortin 2
chr18_-_74207146 0.79 ENST00000443185.2
ZNF516
zinc finger protein 516
chr19_-_56047661 0.79 ENST00000344158.3
SBK2
SH3 domain binding kinase family, member 2
chr3_+_19988736 0.78 ENST00000443878.1
RAB5A
RAB5A, member RAS oncogene family
chr1_+_223889310 0.77 ENST00000434648.1
CAPN2
calpain 2, (m/II) large subunit
chr11_+_394196 0.74 ENST00000331563.2
ENST00000531857.1
PKP3
plakophilin 3
chr1_-_153935738 0.74 ENST00000417348.1
SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr1_-_12679171 0.71 ENST00000606790.1
RP11-474O21.5
RP11-474O21.5
chr16_+_57662596 0.71 ENST00000567397.1
ENST00000568979.1
GPR56
G protein-coupled receptor 56
chr1_-_6662919 0.70 ENST00000377658.4
ENST00000377663.3
KLHL21
kelch-like family member 21
chr11_-_9781068 0.70 ENST00000500698.1
RP11-540A21.2
RP11-540A21.2
chr16_+_30418910 0.69 ENST00000566625.1
ZNF771
zinc finger protein 771
chr16_+_83986827 0.67 ENST00000393306.1
ENST00000565123.1
OSGIN1
oxidative stress induced growth inhibitor 1
chr11_+_66742742 0.66 ENST00000308963.4
C11orf86
chromosome 11 open reading frame 86
chr17_+_7255208 0.65 ENST00000333751.3
KCTD11
potassium channel tetramerization domain containing 11
chr7_+_150065278 0.63 ENST00000519397.1
ENST00000479668.1
ENST00000540729.1
REPIN1
replication initiator 1
chr17_-_55162360 0.61 ENST00000576871.1
ENST00000576313.1
RP11-166P13.3
RP11-166P13.3
chr15_+_41062159 0.60 ENST00000344320.6
C15orf62
chromosome 15 open reading frame 62
chr17_+_48712138 0.60 ENST00000515707.1
ABCC3
ATP-binding cassette, sub-family C (CFTR/MRP), member 3
chr6_-_30685214 0.59 ENST00000425072.1
MDC1
mediator of DNA-damage checkpoint 1
chr17_+_73780852 0.59 ENST00000589666.1
UNK
unkempt family zinc finger
chr1_-_153521597 0.58 ENST00000368712.1
S100A3
S100 calcium binding protein A3
chr1_-_21059029 0.58 ENST00000444387.2
ENST00000375031.1
ENST00000518294.1
SH2D5
SH2 domain containing 5
chr19_-_46145696 0.57 ENST00000588172.1
EML2
echinoderm microtubule associated protein like 2
chr7_+_73245193 0.57 ENST00000340958.2
CLDN4
claudin 4
chr14_+_71165292 0.56 ENST00000553682.1
RP6-65G23.1
RP6-65G23.1
chr16_+_30675654 0.55 ENST00000287468.5
ENST00000395073.2
FBRS
fibrosin
chr19_-_56056888 0.54 ENST00000592464.1
ENST00000420723.3
SBK3
SH3 domain binding kinase family, member 3
chr16_+_57662527 0.54 ENST00000563374.1
ENST00000568234.1
ENST00000565770.1
ENST00000564338.1
ENST00000566164.1
GPR56
G protein-coupled receptor 56
chr11_-_66103932 0.54 ENST00000311320.4
RIN1
Ras and Rab interactor 1
chr17_-_19062424 0.54 ENST00000399083.1
AC007952.6
Uncharacterized protein
chr16_+_58533951 0.53 ENST00000566192.1
ENST00000565088.1
ENST00000568640.1
ENST00000563978.1
ENST00000569923.1
ENST00000356752.4
ENST00000563799.1
ENST00000562999.1
ENST00000570248.1
ENST00000562731.1
ENST00000568424.1
NDRG4
NDRG family member 4
chr16_-_1429674 0.53 ENST00000403703.1
ENST00000397464.1
ENST00000402641.2
UNKL
unkempt family zinc finger-like
chr20_-_634000 0.52 ENST00000381962.3
SRXN1
sulfiredoxin 1
chr18_+_3450161 0.52 ENST00000551402.1
ENST00000577543.1
TGIF1
TGFB-induced factor homeobox 1
chr8_+_22446763 0.52 ENST00000450780.2
ENST00000430850.2
ENST00000447849.1
AC037459.4
Uncharacterized protein
chr1_+_901847 0.51 ENST00000379410.3
ENST00000379409.2
ENST00000379407.3
PLEKHN1
pleckstrin homology domain containing, family N member 1
chr7_+_143078379 0.50 ENST00000449630.1
ENST00000457235.1
ZYX
zyxin
chr16_-_1429627 0.50 ENST00000248104.7
UNKL
unkempt family zinc finger-like
chr8_+_22844913 0.49 ENST00000519685.1
RHOBTB2
Rho-related BTB domain containing 2
chr17_+_78075324 0.49 ENST00000570803.1
GAA
glucosidase, alpha; acid
chr11_-_66104237 0.48 ENST00000530056.1
RIN1
Ras and Rab interactor 1
chr22_+_37959647 0.48 ENST00000415670.1
CDC42EP1
CDC42 effector protein (Rho GTPase binding) 1
chr16_+_67312049 0.48 ENST00000565899.1
PLEKHG4
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr3_+_14474178 0.47 ENST00000452775.1
SLC6A6
solute carrier family 6 (neurotransmitter transporter), member 6
chr9_+_140172200 0.47 ENST00000357503.2
TOR4A
torsin family 4, member A
chr3_+_57094469 0.46 ENST00000334325.1
SPATA12
spermatogenesis associated 12
chr19_+_46001697 0.46 ENST00000451287.2
ENST00000324688.4
PPM1N
protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
chr11_+_47430133 0.44 ENST00000531974.1
ENST00000531419.1
ENST00000531865.1
ENST00000362021.4
ENST00000354884.4
SLC39A13
solute carrier family 39 (zinc transporter), member 13
chr8_+_87111059 0.44 ENST00000285393.3
ATP6V0D2
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr19_+_50431959 0.44 ENST00000595125.1
ATF5
activating transcription factor 5
chr16_-_75301886 0.43 ENST00000393422.2
BCAR1
breast cancer anti-estrogen resistance 1
chr3_-_120400960 0.43 ENST00000476082.2
HGD
homogentisate 1,2-dioxygenase
chr9_+_131902283 0.42 ENST00000436883.1
ENST00000414510.1
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr22_+_45072925 0.42 ENST00000006251.7
PRR5
proline rich 5 (renal)
chr19_-_19739321 0.42 ENST00000588461.1
LPAR2
lysophosphatidic acid receptor 2
chr16_-_122619 0.42 ENST00000262316.6
RHBDF1
rhomboid 5 homolog 1 (Drosophila)
chr11_-_66103867 0.41 ENST00000424433.2
RIN1
Ras and Rab interactor 1
chr11_-_47206965 0.41 ENST00000525725.1
PACSIN3
protein kinase C and casein kinase substrate in neurons 3
chr14_+_38065052 0.41 ENST00000556845.1
TTC6
tetratricopeptide repeat domain 6
chr11_+_36397731 0.41 ENST00000524380.1
PRR5L
proline rich 5 like
chr17_-_79881408 0.41 ENST00000392366.3
MAFG
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
chr16_+_29911666 0.39 ENST00000563177.1
ENST00000483405.1
ASPHD1
aspartate beta-hydroxylase domain containing 1
chr7_-_96339132 0.39 ENST00000413065.1
SHFM1
split hand/foot malformation (ectrodactyly) type 1
chr16_+_1832902 0.39 ENST00000262302.9
ENST00000563136.1
ENST00000565987.1
ENST00000543305.1
ENST00000568287.1
ENST00000565134.1
NUBP2
nucleotide binding protein 2
chr15_+_91416092 0.39 ENST00000559353.1
FURIN
furin (paired basic amino acid cleaving enzyme)
chr22_+_45072958 0.38 ENST00000403581.1
PRR5
proline rich 5 (renal)
chr11_+_844406 0.38 ENST00000397404.1
TSPAN4
tetraspanin 4
chr15_+_64428529 0.38 ENST00000560861.1
SNX1
sorting nexin 1
chr12_+_10365082 0.38 ENST00000545859.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr3_+_49027308 0.38 ENST00000383729.4
ENST00000343546.4
P4HTM
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr17_+_80317121 0.37 ENST00000333437.4
TEX19
testis expressed 19
chr11_+_66360665 0.37 ENST00000310190.4
CCS
copper chaperone for superoxide dismutase
chr15_+_89182156 0.37 ENST00000379224.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr17_-_27503770 0.37 ENST00000533112.1
MYO18A
myosin XVIIIA
chr16_-_4665023 0.36 ENST00000591897.1
UBALD1
UBA-like domain containing 1
chr11_+_36397915 0.36 ENST00000526682.1
ENST00000530252.1
PRR5L
proline rich 5 like
chr1_-_108231101 0.36 ENST00000544443.1
ENST00000415432.2
VAV3
vav 3 guanine nucleotide exchange factor
chr15_+_44829334 0.36 ENST00000535391.1
EIF3J
eukaryotic translation initiation factor 3, subunit J
chr15_+_67458357 0.36 ENST00000537194.2
SMAD3
SMAD family member 3
chr20_+_36012051 0.35 ENST00000373567.2
SRC
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr11_-_65548265 0.35 ENST00000532090.2
AP5B1
adaptor-related protein complex 5, beta 1 subunit
chr5_+_76012009 0.35 ENST00000505600.1
F2R
coagulation factor II (thrombin) receptor
chr19_+_1248547 0.35 ENST00000586757.1
ENST00000300952.2
MIDN
midnolin
chr7_+_73082152 0.35 ENST00000324941.4
ENST00000451519.1
VPS37D
vacuolar protein sorting 37 homolog D (S. cerevisiae)
chr1_+_154377669 0.34 ENST00000368485.3
ENST00000344086.4
IL6R
interleukin 6 receptor
chr16_+_57662419 0.34 ENST00000388812.4
ENST00000538815.1
ENST00000456916.1
ENST00000567154.1
ENST00000388813.5
ENST00000562558.1
ENST00000566271.2
GPR56
G protein-coupled receptor 56
chr3_+_49209023 0.33 ENST00000332780.2
KLHDC8B
kelch domain containing 8B
chr15_+_59903975 0.33 ENST00000560585.1
ENST00000396065.1
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr11_-_65150103 0.33 ENST00000294187.6
ENST00000398802.1
ENST00000360662.3
ENST00000377152.2
ENST00000530936.1
SLC25A45
solute carrier family 25, member 45
chr6_+_30853002 0.33 ENST00000421124.2
ENST00000512725.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr17_+_19122674 0.33 ENST00000436914.1
AC106017.1
Uncharacterized protein
chr10_-_22292675 0.33 ENST00000376946.1
DNAJC1
DnaJ (Hsp40) homolog, subfamily C, member 1
chr19_-_35992780 0.33 ENST00000593342.1
ENST00000601650.1
ENST00000408915.2
DMKN
dermokine
chr1_-_27816641 0.33 ENST00000430629.2
WASF2
WAS protein family, member 2
chr16_+_57662138 0.33 ENST00000562414.1
ENST00000561969.1
ENST00000562631.1
ENST00000563445.1
ENST00000565338.1
ENST00000567702.1
GPR56
G protein-coupled receptor 56
chr1_-_9262678 0.33 ENST00000437157.2
RP3-510D11.1
RP3-510D11.1
chr22_-_30642782 0.33 ENST00000249075.3
LIF
leukemia inhibitory factor
chr12_-_118490217 0.32 ENST00000542304.1
WSB2
WD repeat and SOCS box containing 2
chr17_+_75315654 0.32 ENST00000590595.1
SEPT9
septin 9
chr12_+_6644443 0.32 ENST00000396858.1
GAPDH
glyceraldehyde-3-phosphate dehydrogenase
chr17_+_78075361 0.32 ENST00000577106.1
ENST00000390015.3
GAA
glucosidase, alpha; acid
chr5_-_138534071 0.32 ENST00000394817.2
SIL1
SIL1 nucleotide exchange factor
chr14_+_96722152 0.31 ENST00000216629.6
BDKRB1
bradykinin receptor B1
chr1_-_150208291 0.31 ENST00000533654.1
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr16_-_30125177 0.31 ENST00000406256.3
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr21_-_19775973 0.31 ENST00000284885.3
TMPRSS15
transmembrane protease, serine 15
chr16_-_3074231 0.31 ENST00000572355.1
ENST00000248089.3
ENST00000574980.1
ENST00000354679.3
ENST00000396916.1
ENST00000573842.1
HCFC1R1
host cell factor C1 regulator 1 (XPO1 dependent)
chr1_-_6659876 0.31 ENST00000496707.1
KLHL21
kelch-like family member 21
chr15_-_74504560 0.31 ENST00000449139.2
STRA6
stimulated by retinoic acid 6
chr1_+_36621529 0.31 ENST00000316156.4
MAP7D1
MAP7 domain containing 1
chr19_+_50432400 0.31 ENST00000423777.2
ENST00000600336.1
ENST00000597227.1
ATF5
activating transcription factor 5
chr15_+_41245160 0.31 ENST00000444189.2
ENST00000446533.3
CHAC1
ChaC, cation transport regulator homolog 1 (E. coli)
chr11_-_75201791 0.30 ENST00000529721.1
GDPD5
glycerophosphodiester phosphodiesterase domain containing 5
chr12_-_57030096 0.30 ENST00000549506.1
BAZ2A
bromodomain adjacent to zinc finger domain, 2A
chr3_+_187930429 0.30 ENST00000420410.1
LPP
LIM domain containing preferred translocation partner in lipoma
chr19_-_4559814 0.30 ENST00000586582.1
SEMA6B
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr17_+_25799008 0.30 ENST00000583370.1
ENST00000398988.3
ENST00000268763.6
KSR1
kinase suppressor of ras 1
chr3_+_127317705 0.30 ENST00000480910.1
MCM2
minichromosome maintenance complex component 2
chr5_+_139493665 0.30 ENST00000331327.3
PURA
purine-rich element binding protein A
chr22_-_37584321 0.29 ENST00000397110.2
ENST00000337843.2
C1QTNF6
C1q and tumor necrosis factor related protein 6
chr16_+_29911864 0.29 ENST00000308748.5
ASPHD1
aspartate beta-hydroxylase domain containing 1
chr12_-_53625958 0.29 ENST00000327550.3
ENST00000546717.1
ENST00000425354.2
ENST00000394426.1
RARG
retinoic acid receptor, gamma
chr3_-_87040259 0.29 ENST00000383698.3
VGLL3
vestigial like 3 (Drosophila)
chrX_-_49056635 0.29 ENST00000472598.1
ENST00000538567.1
ENST00000479808.1
ENST00000263233.4
SYP
synaptophysin
chr9_-_130341268 0.29 ENST00000373314.3
FAM129B
family with sequence similarity 129, member B
chr11_+_844067 0.28 ENST00000397406.1
ENST00000409543.2
ENST00000525201.1
TSPAN4
tetraspanin 4
chr17_+_80193644 0.28 ENST00000582946.1
SLC16A3
solute carrier family 16 (monocarboxylate transporter), member 3
chr6_+_143447322 0.28 ENST00000458219.1
AIG1
androgen-induced 1
chr19_+_13842559 0.28 ENST00000586600.1
CCDC130
coiled-coil domain containing 130
chr11_+_28724129 0.28 ENST00000513853.1
RP11-115J23.1
RP11-115J23.1
chr12_+_7023491 0.28 ENST00000541477.1
ENST00000229277.1
ENO2
enolase 2 (gamma, neuronal)
chr15_+_75335604 0.28 ENST00000563393.1
PPCDC
phosphopantothenoylcysteine decarboxylase
chr16_+_30751953 0.28 ENST00000483578.1
RP11-2C24.4
RP11-2C24.4
chr17_-_48133054 0.27 ENST00000499842.1
RP11-1094H24.4
RP11-1094H24.4
chr2_+_120189422 0.27 ENST00000306406.4
TMEM37
transmembrane protein 37
chr3_-_178865747 0.27 ENST00000435560.1
RP11-360P21.2
RP11-360P21.2
chr17_-_33415837 0.27 ENST00000414419.2
RFFL
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr9_+_140135665 0.27 ENST00000340384.4
TUBB4B
tubulin, beta 4B class IVb
chr11_+_101983176 0.27 ENST00000524575.1
YAP1
Yes-associated protein 1
chr16_+_30006615 0.27 ENST00000563197.1
INO80E
INO80 complex subunit E
chr17_+_79071365 0.26 ENST00000576756.1
BAIAP2
BAI1-associated protein 2
chr6_+_30852130 0.26 ENST00000428153.2
ENST00000376568.3
ENST00000452441.1
ENST00000515219.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr4_+_102268904 0.26 ENST00000527564.1
ENST00000529296.1
AP001816.1
Uncharacterized protein
chr17_-_42994283 0.26 ENST00000593179.1
GFAP
glial fibrillary acidic protein
chr11_-_71781096 0.26 ENST00000535087.1
ENST00000535838.1
NUMA1
nuclear mitotic apparatus protein 1
chr17_-_25568687 0.25 ENST00000581944.1
RP11-663N22.1
RP11-663N22.1
chr19_-_44008863 0.25 ENST00000601646.1
PHLDB3
pleckstrin homology-like domain, family B, member 3
chr5_-_141030943 0.25 ENST00000522783.1
ENST00000519800.1
ENST00000435817.2
FCHSD1
FCH and double SH3 domains 1
chr11_-_96076334 0.25 ENST00000524717.1
MAML2
mastermind-like 2 (Drosophila)
chr2_+_201981663 0.25 ENST00000433445.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr11_+_6411670 0.25 ENST00000530395.1
ENST00000527275.1
SMPD1
sphingomyelin phosphodiesterase 1, acid lysosomal
chr17_+_4853442 0.25 ENST00000522301.1
ENO3
enolase 3 (beta, muscle)
chr10_-_4285923 0.25 ENST00000418372.1
ENST00000608792.1
LINC00702
long intergenic non-protein coding RNA 702
chr9_+_131902346 0.24 ENST00000432124.1
ENST00000435305.1
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr12_-_118490403 0.24 ENST00000535496.1
WSB2
WD repeat and SOCS box containing 2
chr16_+_30953696 0.24 ENST00000566320.2
ENST00000565939.1
FBXL19
F-box and leucine-rich repeat protein 19
chr7_+_102290772 0.24 ENST00000507450.1
SPDYE2B
speedy/RINGO cell cycle regulator family member E2B
chr3_-_47950745 0.24 ENST00000429422.1
MAP4
microtubule-associated protein 4
chr11_+_67351213 0.24 ENST00000398603.1
GSTP1
glutathione S-transferase pi 1
chr8_+_82066514 0.24 ENST00000519412.1
ENST00000521953.1
RP11-1149M10.2
RP11-1149M10.2
chr20_-_62258394 0.24 ENST00000370077.1
GMEB2
glucocorticoid modulatory element binding protein 2
chr19_+_3366547 0.23 ENST00000341919.3
ENST00000590282.1
ENST00000443272.2
NFIC
nuclear factor I/C (CCAAT-binding transcription factor)
chr22_-_30970560 0.23 ENST00000402369.1
ENST00000406361.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chr3_+_48507621 0.23 ENST00000456089.1
TREX1
three prime repair exonuclease 1
chr17_-_19062187 0.23 ENST00000399087.1
ENST00000436381.1
AC007952.6
Uncharacterized protein
chr2_-_224467002 0.23 ENST00000421386.1
ENST00000433889.1
SCG2
secretogranin II
chr9_+_35673853 0.23 ENST00000378357.4
CA9
carbonic anhydrase IX
chr12_+_7341759 0.23 ENST00000455147.2
ENST00000540398.1
PEX5
peroxisomal biogenesis factor 5
chr3_+_48507210 0.23 ENST00000433541.1
ENST00000422277.2
ENST00000436480.2
ENST00000444177.1
TREX1
three prime repair exonuclease 1
chr12_+_56546363 0.23 ENST00000551834.1
ENST00000552568.1
MYL6B
myosin, light chain 6B, alkali, smooth muscle and non-muscle
chr12_-_53343560 0.23 ENST00000548998.1
KRT8
keratin 8
chr1_+_222988406 0.23 ENST00000448808.1
ENST00000457636.1
ENST00000439440.1
RP11-452F19.3
RP11-452F19.3
chr15_-_99789736 0.23 ENST00000560235.1
ENST00000394132.2
ENST00000560860.1
ENST00000558078.1
ENST00000394136.1
ENST00000262074.4
ENST00000558613.1
ENST00000394130.1
ENST00000560772.1
TTC23
tetratricopeptide repeat domain 23
chr16_+_67571351 0.23 ENST00000428437.2
ENST00000569253.1
FAM65A
family with sequence similarity 65, member A
chr17_+_78075498 0.22 ENST00000302262.3
GAA
glucosidase, alpha; acid
chr17_-_45928521 0.22 ENST00000536300.1
SP6
Sp6 transcription factor
chr1_+_19638788 0.22 ENST00000375155.3
ENST00000375153.3
ENST00000400548.2
PQLC2
PQ loop repeat containing 2
chr1_-_158656488 0.22 ENST00000368147.4
SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr12_-_53297432 0.22 ENST00000546900.1
KRT8
keratin 8
chr8_-_145025044 0.22 ENST00000322810.4
PLEC
plectin
chr6_-_33266492 0.22 ENST00000425946.1
RGL2
ral guanine nucleotide dissociation stimulator-like 2

Network of associatons between targets according to the STRING database.

First level regulatory network of FOSL2_SMARCC1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 5.1 GO:0002159 desmosome assembly(GO:0002159)
0.3 1.0 GO:0043181 vacuolar sequestering(GO:0043181)
0.3 2.0 GO:0098886 modification of dendritic spine(GO:0098886)
0.2 1.4 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.2 1.8 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.2 0.2 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.2 0.2 GO:0050818 regulation of coagulation(GO:0050818) negative regulation of coagulation(GO:0050819)
0.1 0.6 GO:0015722 canalicular bile acid transport(GO:0015722)
0.1 0.4 GO:0032903 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.1 0.5 GO:1903028 positive regulation of opsonization(GO:1903028)
0.1 0.4 GO:0015680 intracellular copper ion transport(GO:0015680)
0.1 0.6 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.1 0.2 GO:0099552 trans-synaptic signalling, modulating synaptic transmission(GO:0099550) trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.1 0.3 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.1 1.4 GO:0006477 protein sulfation(GO:0006477)
0.1 0.4 GO:0002384 hepatic immune response(GO:0002384)
0.1 0.3 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 0.4 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.1 0.4 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.1 0.6 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 1.6 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.4 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.1 0.2 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.1 1.2 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.1 0.5 GO:0061143 alveolar primary septum development(GO:0061143)
0.1 0.3 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1 0.2 GO:1903401 L-lysine transmembrane transport(GO:1903401)
0.1 1.1 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.2 GO:0061727 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 0.2 GO:0071451 cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451)
0.1 1.0 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.1 0.4 GO:0070295 renal water absorption(GO:0070295)
0.1 0.3 GO:0052501 induction of programmed cell death(GO:0012502) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501)
0.1 1.1 GO:0015886 heme transport(GO:0015886)
0.1 0.3 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.1 0.1 GO:0034368 macromolecular complex remodeling(GO:0034367) protein-lipid complex remodeling(GO:0034368) plasma lipoprotein particle remodeling(GO:0034369)
0.1 0.4 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.1 0.2 GO:0035425 autocrine signaling(GO:0035425)
0.1 0.4 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.3 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 0.2 GO:0060738 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908) positive regulation of immature T cell proliferation in thymus(GO:0033092) right lung development(GO:0060458) primary prostatic bud elongation(GO:0060516) epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738) sclerotome development(GO:0061056)
0.1 0.3 GO:0060426 lung vasculature development(GO:0060426)
0.1 0.6 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.5 GO:0051036 regulation of endosome size(GO:0051036)
0.0 0.4 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.2 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0 2.2 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.1 GO:0015793 glycerol transport(GO:0015793)
0.0 0.2 GO:1901093 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.0 0.6 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.2 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.0 0.2 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.1 GO:0006043 glucosamine catabolic process(GO:0006043)
0.0 1.1 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.3 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.0 0.7 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.4 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.0 0.2 GO:0035640 exploration behavior(GO:0035640) locomotory exploration behavior(GO:0035641)
0.0 0.2 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.0 0.3 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.0 0.5 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.3 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.7 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.2 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.1 GO:0033625 positive regulation of integrin activation(GO:0033625)
0.0 0.5 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 0.1 GO:0051043 regulation of membrane protein ectodomain proteolysis(GO:0051043)
0.0 0.1 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 0.2 GO:0023021 termination of signal transduction(GO:0023021)
0.0 0.5 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.0 GO:0031272 regulation of pseudopodium assembly(GO:0031272)
0.0 0.1 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.0 0.2 GO:0051697 protein delipidation(GO:0051697)
0.0 0.2 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.1 GO:0051414 response to cortisol(GO:0051414)
0.0 0.1 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) positive regulation of connective tissue replacement(GO:1905205)
0.0 0.2 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 1.1 GO:0010842 retina layer formation(GO:0010842)
0.0 0.3 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.0 0.3 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.0 0.2 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 2.8 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.3 GO:1902846 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.0 0.4 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.1 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.0 0.1 GO:0046541 saliva secretion(GO:0046541)
0.0 0.5 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.6 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.1 GO:0046521 sphingoid catabolic process(GO:0046521)
0.0 0.5 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.0 0.1 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.0 0.1 GO:1990535 neuron projection maintenance(GO:1990535)
0.0 0.1 GO:0039019 pronephric nephron development(GO:0039019)
0.0 0.1 GO:0051097 negative regulation of helicase activity(GO:0051097) positive regulation of thymocyte apoptotic process(GO:0070245) oligodendrocyte apoptotic process(GO:0097252)
0.0 0.1 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.4 GO:0006751 glutathione catabolic process(GO:0006751)
0.0 0.1 GO:0060126 somatotropin secreting cell differentiation(GO:0060126)
0.0 0.1 GO:1903365 regulation of fear response(GO:1903365) regulation of behavioral fear response(GO:2000822)
0.0 0.2 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.2 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.4 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.0 GO:1903464 negative regulation of mitotic cell cycle DNA replication(GO:1903464)
0.0 0.0 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.1 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.2 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 0.1 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.3 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.2 GO:0097240 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.9 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.9 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.6 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.4 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.1 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 2.5 GO:0030838 positive regulation of actin filament polymerization(GO:0030838)
0.0 0.1 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.1 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536) positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
0.0 0.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.3 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.1 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 0.3 GO:0009615 response to virus(GO:0009615)
0.0 0.1 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.0 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.0 GO:1904995 negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.0 0.2 GO:0044146 negative regulation of growth of symbiont in host(GO:0044130) negative regulation of growth of symbiont involved in interaction with host(GO:0044146)
0.0 0.4 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.2 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 0.1 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.1 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.4 GO:0035729 cellular response to hepatocyte growth factor stimulus(GO:0035729)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.5 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.0 GO:0030264 nuclear fragmentation involved in apoptotic nuclear change(GO:0030264)
0.0 0.1 GO:0048687 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.0 0.1 GO:0060356 leucine import(GO:0060356)
0.0 0.1 GO:0009608 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.0 0.1 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.0 0.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.4 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.7 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.4 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.1 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.0 0.3 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.1 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.5 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.0 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.2 GO:0048505 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0 0.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.2 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0 0.1 GO:0060283 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.0 0.1 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.1 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.0 0.0 GO:0006218 uridine catabolic process(GO:0006218)
0.0 0.2 GO:0071803 positive regulation of podosome assembly(GO:0071803)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0097444 spine apparatus(GO:0097444)
0.4 1.8 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.2 0.9 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 4.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 0.5 GO:0070110 ciliary neurotrophic factor receptor complex(GO:0070110)
0.1 0.4 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.1 1.1 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1 1.0 GO:0005827 polar microtubule(GO:0005827)
0.1 0.7 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.2 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.1 2.7 GO:0031527 filopodium membrane(GO:0031527)
0.1 1.6 GO:0031932 TORC2 complex(GO:0031932)
0.1 0.9 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.2 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.1 0.6 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.3 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 0.4 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.5 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.2 GO:0044753 amphisome(GO:0044753)
0.0 0.4 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.3 GO:0097452 GAIT complex(GO:0097452)
0.0 1.8 GO:0043034 costamere(GO:0043034)
0.0 0.2 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 0.1 GO:0020003 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.0 0.2 GO:0032437 cuticular plate(GO:0032437)
0.0 0.4 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.6 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.3 GO:0070652 HAUS complex(GO:0070652)
0.0 0.2 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.2 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 4.0 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.1 GO:0043209 myelin sheath(GO:0043209)
0.0 0.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.6 GO:0032590 dendrite membrane(GO:0032590)
0.0 1.1 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.3 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.3 GO:0097342 ripoptosome(GO:0097342)
0.0 0.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.2 GO:0042599 lamellar body(GO:0042599)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 1.2 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.3 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.0 GO:0016342 catenin complex(GO:0016342)
0.0 0.0 GO:0000814 ESCRT II complex(GO:0000814)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.3 0.8 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.2 5.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.2 1.5 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.2 0.6 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.2 1.8 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.2 0.5 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897) interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981) ciliary neurotrophic factor binding(GO:0070119)
0.2 0.5 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 1.2 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1 2.7 GO:0005522 profilin binding(GO:0005522)
0.1 0.3 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.1 0.3 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.1 0.3 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.4 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.1 0.6 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.3 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.7 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.3 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 0.4 GO:1990460 leptin receptor binding(GO:1990460)
0.1 0.3 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.1 0.3 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.4 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 0.3 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 0.4 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 0.2 GO:0070984 SET domain binding(GO:0070984)
0.1 0.2 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 1.1 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.2 GO:0019862 IgA binding(GO:0019862)
0.1 0.3 GO:0033906 protein tyrosine kinase inhibitor activity(GO:0030292) hyaluronoglucuronidase activity(GO:0033906)
0.1 0.4 GO:0070026 nitric oxide binding(GO:0070026)
0.1 0.4 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 0.8 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 1.2 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 2.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.2 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.1 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.2 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.0 0.2 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.4 GO:0071253 connexin binding(GO:0071253)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.1 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 0.1 GO:0008859 exoribonuclease II activity(GO:0008859)
0.0 1.1 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.4 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.0 0.5 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.2 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.1 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.1 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.3 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.1 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.0 0.5 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.3 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.2 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.1 GO:0005427 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.0 0.2 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:1903135 cupric ion binding(GO:1903135)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493) C-C chemokine binding(GO:0019957)
0.0 0.2 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 1.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0036435 IkappaB kinase activity(GO:0008384) K48-linked polyubiquitin binding(GO:0036435)
0.0 0.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.4 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.6 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.2 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.1 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.5 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.4 GO:0005343 organic acid:sodium symporter activity(GO:0005343)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.0 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.0 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.0 GO:0003955 NAD(P)H dehydrogenase (quinone) activity(GO:0003955)
0.0 0.1 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.4 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.4 GO:0031418 L-ascorbic acid binding(GO:0031418)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.1 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 3.7 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.4 ST STAT3 PATHWAY STAT3 Pathway
0.0 1.2 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.4 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.6 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.4 PID AP1 PATHWAY AP-1 transcription factor network
0.0 1.2 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.8 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.6 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 0.1 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 1.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 1.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.6 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 1.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.1 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.4 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.4 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.0 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.6 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.8 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.1 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.6 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.2 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation