ISMARA results: FOSL2

Project

A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

Navigation

Downloads

Results for FOSL2_SMARCC1

Z-value: 1.49

Motif logo

Transcription factors associated with FOSL2_SMARCC1

Gene Symbol	Gene ID	Gene Info
FOSL2 Ensembl NCBI GeneCards UniProt	ENSG00000075426.7	FOS like 2, AP-1 transcription factor subunit
SMARCC1 Ensembl NCBI GeneCards UniProt	ENSG00000173473.6	SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
SMARCC1	hg19_v2_chr3_-_47823298_47823423	0.99	1.2e-02	Click!
FOSL2	hg19_v2_chr2_+_28615669_28615733	0.99	1.3e-02	Click!

Activity profile of FOSL2_SMARCC1 motif

Sorted Z-values of FOSL2_SMARCC1 motif

Top targets:

Search:

Show entries

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr19_+_46009837 Show fit	2.72	ENST00000589627.1	VASP Ensembl NCBI GeneCards UniProt Show fit	vasodilator-stimulated phosphoprotein
chr11_+_393428 Show fit	2.36	ENST00000533249.1 ENST00000527442.1	PKP3 Ensembl NCBI GeneCards UniProt Show fit	plakophilin 3
chr5_-_176923803 Show fit	2.00	ENST00000506161.1	PDLIM7 Ensembl NCBI GeneCards UniProt Show fit	PDZ and LIM domain 7 (enigma)
chr11_+_394145 Show fit	1.89	ENST00000528036.1	PKP3 Ensembl NCBI GeneCards UniProt Show fit	plakophilin 3
chr11_-_67141640 Show fit	1.77	ENST00000533438.1	CLCF1 Ensembl NCBI GeneCards UniProt Show fit	cardiotrophin-like cytokine factor 1
chr5_+_149877440 Show fit	1.31	ENST00000518299.1	NDST1 Ensembl NCBI GeneCards UniProt Show fit	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr11_-_62323702 Show fit	1.19	ENST00000530285.1	AHNAK Ensembl NCBI GeneCards UniProt Show fit	AHNAK nucleoprotein
chr17_+_7123207 Show fit	1.16	ENST00000584103.1 ENST00000579886.2	ACADVL Ensembl NCBI GeneCards UniProt Show fit	acyl-CoA dehydrogenase, very long chain
chr12_+_48152774 Show fit	1.15	ENST00000549243.1	SLC48A1 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 48 (heme transporter), member 1
chr5_-_176923846 Show fit	1.07	ENST00000506537.1	PDLIM7 Ensembl NCBI GeneCards UniProt Show fit	PDZ and LIM domain 7 (enigma)

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of FOSL2_SMARCC1

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	5.1	GO:0002159	desmosome assembly(GO:0002159)
0.0	2.8	GO:0045669	positive regulation of osteoblast differentiation(GO:0045669)
0.0	2.5	GO:0030838	positive regulation of actin filament polymerization(GO:0030838)
0.0	2.2	GO:0071577	zinc II ion transmembrane transport(GO:0071577)
0.3	2.0	GO:0098886	modification of dendritic spine(GO:0098886)
0.2	1.8	GO:0048295	positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.1	1.6	GO:0038203	TORC2 signaling(GO:0038203)
0.2	1.4	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)
0.1	1.4	GO:0006477	protein sulfation(GO:0006477)
0.1	1.2	GO:0046322	negative regulation of fatty acid oxidation(GO:0046322)

Showing 1 to 10 of 163 entries

Gene overrepresentation in cellular_component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	4.5	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.0	4.0	GO:0005913	cell-cell adherens junction(GO:0005913)
0.1	2.7	GO:0031527	filopodium membrane(GO:0031527)
0.6	1.9	GO:0097444	spine apparatus(GO:0097444)
0.4	1.8	GO:0097058	CRLF-CLCF1 complex(GO:0097058)
0.0	1.8	GO:0043034	costamere(GO:0043034)
0.1	1.6	GO:0031932	TORC2 complex(GO:0031932)
0.0	1.2	GO:0035577	azurophil granule membrane(GO:0035577)
0.1	1.1	GO:0070033	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0	1.1	GO:0009295	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)

Showing 1 to 10 of 54 entries

Gene overrepresentation in molecular_function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	5.1	GO:0045294	alpha-catenin binding(GO:0045294)
0.1	2.7	GO:0005522	profilin binding(GO:0005522)
0.0	2.2	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.2	1.8	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.0	1.8	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.2	1.5	GO:0050119	N-acetylglucosamine deacetylase activity(GO:0050119)
0.1	1.2	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1	1.2	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.1	1.1	GO:0015232	heme transporter activity(GO:0015232)
0.0	1.1	GO:0017049	GTP-Rho binding(GO:0017049)

Showing 1 to 10 of 99 entries

Gene overrepresentation in C2:CP category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	3.7	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.1	3.3	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	1.3	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	1.2	PID RAS PATHWAY	Regulation of Ras family activation
0.0	1.2	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	0.8	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.6	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.6	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.4	ST STAT3 PATHWAY	STAT3 Pathway
0.0	0.4	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling

Showing 1 to 10 of 12 entries

Gene overrepresentation in C2:CP:REACTOME category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.6	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	1.7	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	1.5	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.1	1.2	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	1.1	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	1.0	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.8	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.8	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.6	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.6	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks

Showing 1 to 10 of 26 entries

Results for FOSL2_SMARCC1

Z-value: 1.49

Motif logo

Transcription factors associated with FOSL2_SMARCC1

Activity-expression correlation:

Activity profile of FOSL2_SMARCC1 motif

Sorted Z-values of FOSL2_SMARCC1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of FOSL2_SMARCC1

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: