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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)
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Results for ETV1_ERF_FEV_ELF1
Z-value: 1.19
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Transcription factors associated with ETV1_ERF_FEV_ELF1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
| ENSG00000006468.9 | ETS variant transcription factor 1 | |
| ENSG00000105722.5 | ETS2 repressor factor | |
| ENSG00000163497.2 | FEV transcription factor, ETS family member | |
| ENSG00000120690.9 | E74 like ETS transcription factor 1 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ETV1 | hg19_v2_chr7_-_14026063_14026091 | -0.97 | 2.6e-02 | Click! |
| ERF | hg19_v2_chr19_-_42759300_42759324 | 0.97 | 3.2e-02 | Click! |
| ELF1 | hg19_v2_chr13_-_41635512_41635576 | 0.94 | 6.3e-02 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of ETV1_ERF_FEV_ELF1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.0 | GO:0031167 | rRNA methylation(GO:0031167) |
| 0.1 | 2.8 | GO:0050651 | dermatan sulfate proteoglycan biosynthetic process(GO:0050651) |
| 0.1 | 2.1 | GO:1901663 | ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663) |
| 0.0 | 2.1 | GO:1901998 | toxin transport(GO:1901998) |
| 0.2 | 2.0 | GO:0000821 | regulation of arginine metabolic process(GO:0000821) |
| 0.2 | 2.0 | GO:1904327 | protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379) |
| 0.2 | 1.8 | GO:0010836 | negative regulation of protein ADP-ribosylation(GO:0010836) |
| 0.2 | 1.8 | GO:0006049 | UDP-N-acetylglucosamine catabolic process(GO:0006049) |
| 0.2 | 1.8 | GO:0017182 | peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) |
| 0.1 | 1.8 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.7 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.2 | 2.1 | GO:0071818 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
| 0.1 | 2.0 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.0 | 2.0 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.1 | 1.9 | GO:0048188 | Set1C/COMPASS complex(GO:0048188) |
| 0.1 | 1.6 | GO:0070765 | gamma-secretase complex(GO:0070765) |
| 0.2 | 1.5 | GO:0005683 | U7 snRNP(GO:0005683) |
| 0.0 | 1.5 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.2 | 1.4 | GO:1990130 | Iml1 complex(GO:1990130) |
| 0.1 | 1.3 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 2.8 | GO:0015018 | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018) |
| 0.1 | 2.6 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.0 | 2.4 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
| 0.0 | 2.2 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.3 | 2.0 | GO:0000179 | rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) |
| 0.1 | 2.0 | GO:0015174 | basic amino acid transmembrane transporter activity(GO:0015174) |
| 0.1 | 2.0 | GO:0015643 | toxic substance binding(GO:0015643) |
| 0.2 | 1.8 | GO:0003827 | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827) |
| 0.6 | 1.7 | GO:0016731 | ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731) |
| 0.1 | 1.7 | GO:0015002 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.9 | ST GAQ PATHWAY | G alpha q Pathway |
| 0.0 | 1.8 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.0 | 1.5 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.0 | 1.4 | PID AURORA A PATHWAY | Aurora A signaling |
| 0.0 | 1.2 | SA PTEN PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |
| 0.0 | 0.9 | PID TRAIL PATHWAY | TRAIL signaling pathway |
| 0.0 | 0.8 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.0 | 0.5 | ST GA12 PATHWAY | G alpha 12 Pathway |
| 0.0 | 0.5 | PID HIV NEF PATHWAY | HIV-1 Nef: Negative effector of Fas and TNF-alpha |
| 0.0 | 0.4 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.8 | REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
| 0.0 | 2.3 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 0.0 | 1.9 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.0 | 1.8 | REACTOME PROTEIN FOLDING | Genes involved in Protein folding |
| 0.0 | 1.7 | REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
| 0.1 | 1.6 | REACTOME SIGNALING BY NOTCH4 | Genes involved in Signaling by NOTCH4 |
| 0.0 | 1.5 | REACTOME MITOCHONDRIAL TRNA AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
| 0.1 | 1.3 | REACTOME SIGNAL ATTENUATION | Genes involved in Signal attenuation |
| 0.0 | 1.3 | REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
| 0.0 | 1.2 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |