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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)
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Results for ERG
Z-value: 0.74
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Transcription factors associated with ERG
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr15_-_71184724 Show fit | 0.54 |
ENST00000560604.1
|
THAP domain containing 10 |
|
| chr3_-_47324242 Show fit | 0.38 |
ENST00000456548.1
ENST00000432493.1 ENST00000335044.2 ENST00000444589.2 |
kinesin family member 9 |
|
| chr22_-_36925124 Show fit | 0.37 |
ENST00000457241.1
|
eukaryotic translation initiation factor 3, subunit D |
|
| chr19_-_10305302 Show fit | 0.35 |
ENST00000592054.1
|
DNA (cytosine-5-)-methyltransferase 1 |
|
| chr12_-_110888103 Show fit | 0.35 |
ENST00000426440.1
ENST00000228825.7 |
actin related protein 2/3 complex, subunit 3, 21kDa |
|
| chr8_-_38034234 Show fit | 0.33 |
ENST00000311351.4
|
LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
|
| chr19_-_51875894 Show fit | 0.32 |
ENST00000600427.1
ENST00000595217.1 ENST00000221978.5 |
natural killer cell group 7 sequence |
|
| chr19_-_10450328 Show fit | 0.30 |
ENST00000160262.5
|
intercellular adhesion molecule 3 |
|
| chr12_-_105629852 Show fit | 0.30 |
ENST00000551662.1
ENST00000553097.1 |
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 |
|
| chr1_+_112016414 Show fit | 0.30 |
ENST00000343534.5
ENST00000369718.3 |
chromosome 1 open reading frame 162 |
Network of associatons between targets according to the STRING database.
First level regulatory network of ERG
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.1 | GO:0006363 | termination of RNA polymerase I transcription(GO:0006363) |
| 0.1 | 0.9 | GO:0044565 | dendritic cell proliferation(GO:0044565) |
| 0.1 | 0.9 | GO:0060715 | syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715) |
| 0.0 | 0.9 | GO:0006911 | phagocytosis, engulfment(GO:0006911) |
| 0.2 | 0.8 | GO:0001732 | formation of cytoplasmic translation initiation complex(GO:0001732) |
| 0.0 | 0.8 | GO:0071801 | regulation of podosome assembly(GO:0071801) |
| 0.0 | 0.8 | GO:0042407 | cristae formation(GO:0042407) |
| 0.0 | 0.7 | GO:0030488 | tRNA methylation(GO:0030488) |
| 0.0 | 0.6 | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) |
| 0.1 | 0.5 | GO:1903588 | negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.3 | GO:0002102 | podosome(GO:0002102) |
| 0.1 | 1.2 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
| 0.0 | 1.0 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.0 | 0.7 | GO:0032156 | septin cytoskeleton(GO:0032156) |
| 0.1 | 0.6 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
| 0.0 | 0.5 | GO:0000439 | core TFIIH complex(GO:0000439) |
| 0.0 | 0.5 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 0.0 | 0.5 | GO:0030870 | Mre11 complex(GO:0030870) |
| 0.0 | 0.5 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
| 0.0 | 0.5 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.5 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.2 | 0.8 | GO:0098808 | mRNA cap binding(GO:0098808) |
| 0.0 | 0.8 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 0.0 | 0.8 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 0.0 | 0.8 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.0 | 0.7 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.0 | 0.7 | GO:0051721 | protein phosphatase 2A binding(GO:0051721) |
| 0.0 | 0.7 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.0 | 0.6 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.0 | 0.6 | GO:0001671 | ATPase activator activity(GO:0001671) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.3 | PID BARD1 PATHWAY | BARD1 signaling events |
| 0.0 | 1.3 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
| 0.0 | 1.0 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.0 | 0.8 | PID REELIN PATHWAY | Reelin signaling pathway |
| 0.0 | 0.7 | PID ATR PATHWAY | ATR signaling pathway |
| 0.0 | 0.7 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.0 | 0.6 | PID IL5 PATHWAY | IL5-mediated signaling events |
| 0.0 | 0.6 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.0 | 0.6 | PID GMCSF PATHWAY | GMCSF-mediated signaling events |
| 0.0 | 0.5 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.3 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.0 | 1.3 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.0 | 1.0 | REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS | Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis |
| 0.0 | 0.9 | REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter |
| 0.0 | 0.9 | REACTOME GENERATION OF SECOND MESSENGER MOLECULES | Genes involved in Generation of second messenger molecules |
| 0.0 | 0.8 | REACTOME PECAM1 INTERACTIONS | Genes involved in PECAM1 interactions |
| 0.0 | 0.7 | REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
| 0.0 | 0.7 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 0.0 | 0.6 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 0.0 | 0.6 | REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON | Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon |