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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for EN2_GBX2_LBX2

Z-value: 0.17

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Transcription factors associated with EN2_GBX2_LBX2

Gene Symbol Gene ID Gene Info
ENSG00000164778.4 engrailed homeobox 2
ENSG00000168505.6 gastrulation brain homeobox 2
ENSG00000179528.11 ladybird homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EN2hg19_v2_chr7_+_155250824_155250824-0.881.2e-01Click!
LBX2hg19_v2_chr2_-_74730087_747301110.752.5e-01Click!
GBX2hg19_v2_chr2_-_237076992_2370770120.148.6e-01Click!

Activity profile of EN2_GBX2_LBX2 motif

Sorted Z-values of EN2_GBX2_LBX2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_99716914 0.14 ENST00000431404.2
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr12_+_52695617 0.12 ENST00000293525.5
keratin 86
chr6_+_26199737 0.12 ENST00000359985.1
histone cluster 1, H2bf
chr12_-_89746264 0.09 ENST00000548755.1
dual specificity phosphatase 6
chr12_-_89746173 0.08 ENST00000308385.6
dual specificity phosphatase 6
chr6_-_39693111 0.07 ENST00000373215.3
ENST00000538893.1
ENST00000287152.7
ENST00000373216.3
kinesin family member 6
chr6_-_26250835 0.06 ENST00000446824.2
histone cluster 1, H3f
chr12_-_57328187 0.06 ENST00000293502.1
short chain dehydrogenase/reductase family 9C, member 7
chr1_-_149785236 0.05 ENST00000331491.1
histone cluster 2, H3d
chr12_+_78359999 0.05 ENST00000550503.1
neuron navigator 3
chr19_-_14064114 0.05 ENST00000585607.1
ENST00000538517.2
ENST00000587458.1
ENST00000538371.2
podocan-like 1
chr20_+_18488137 0.05 ENST00000450074.1
ENST00000262544.2
ENST00000336714.3
ENST00000377475.3
Sec23 homolog B (S. cerevisiae)
chr7_+_100136811 0.04 ENST00000300176.4
ENST00000262935.4
ArfGAP with FG repeats 2
chr14_+_32798547 0.04 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
A kinase (PRKA) anchor protein 6
chr20_+_18447771 0.04 ENST00000377603.4
polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
chr12_-_56694142 0.04 ENST00000550655.1
ENST00000548567.1
ENST00000551430.2
ENST00000351328.3
citrate synthase
chr6_-_26032288 0.04 ENST00000244661.2
histone cluster 1, H3b
chr19_+_48949087 0.04 ENST00000598711.1
glutamate-rich WD repeat containing 1
chr4_-_105416039 0.04 ENST00000394767.2
CXXC finger protein 4
chr6_-_31107127 0.04 ENST00000259845.4
psoriasis susceptibility 1 candidate 2
chr14_-_95236551 0.04 ENST00000238558.3
goosecoid homeobox
chr11_-_124981475 0.04 ENST00000532156.1
ENST00000532407.1
ENST00000279968.4
ENST00000527766.1
ENST00000529583.1
ENST00000524373.1
ENST00000527271.1
ENST00000526175.1
ENST00000529609.1
ENST00000533273.1
ENST00000531909.1
ENST00000529530.1
transmembrane protein 218
chr16_-_29910853 0.04 ENST00000308713.5
seizure related 6 homolog (mouse)-like 2
chr11_-_31531121 0.03 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr17_+_18086392 0.03 ENST00000541285.1
alkB, alkylation repair homolog 5 (E. coli)
chr7_-_137028534 0.03 ENST00000348225.2
pleiotrophin
chr6_+_130339710 0.03 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
l(3)mbt-like 3 (Drosophila)
chr3_-_178984759 0.03 ENST00000349697.2
ENST00000497599.1
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr15_-_55562479 0.03 ENST00000564609.1
RAB27A, member RAS oncogene family
chr15_-_55562582 0.03 ENST00000396307.2
RAB27A, member RAS oncogene family
chr7_-_137028498 0.03 ENST00000393083.2
pleiotrophin
chr4_+_144354644 0.03 ENST00000512843.1
GRB2-associated binding protein 1
chr1_-_118472216 0.03 ENST00000369443.5
ganglioside induced differentiation associated protein 2
chr6_+_155538093 0.03 ENST00000462408.2
T-cell lymphoma invasion and metastasis 2
chr6_+_26020672 0.03 ENST00000357647.3
histone cluster 1, H3a
chr3_-_178103144 0.03 ENST00000417383.1
ENST00000418585.1
ENST00000411727.1
ENST00000439810.1
RP11-33A14.1
chr6_+_4087664 0.03 ENST00000430835.2
chromosome 6 open reading frame 201
chr16_+_9185450 0.02 ENST00000327827.7
chromosome 16 open reading frame 72
chr1_-_151762943 0.02 ENST00000368825.3
ENST00000368823.1
ENST00000458431.2
ENST00000368827.6
ENST00000368824.3
tudor and KH domain containing
chr12_+_7014064 0.02 ENST00000443597.2
leucine rich repeat containing 23
chr1_+_153747746 0.02 ENST00000368661.3
solute carrier family 27 (fatty acid transporter), member 3
chr1_+_153746683 0.02 ENST00000271857.2
solute carrier family 27 (fatty acid transporter), member 3
chr6_-_32145861 0.02 ENST00000336984.6
1-acylglycerol-3-phosphate O-acyltransferase 1
chr3_-_180397256 0.02 ENST00000442201.2
coiled-coil domain containing 39
chr19_+_45973120 0.02 ENST00000592811.1
ENST00000586615.1
FBJ murine osteosarcoma viral oncogene homolog B
chr11_+_67250490 0.02 ENST00000528641.2
ENST00000279146.3
aryl hydrocarbon receptor interacting protein
chr3_-_27764190 0.02 ENST00000537516.1
eomesodermin
chr7_+_138145076 0.02 ENST00000343526.4
tripartite motif containing 24
chr19_-_14640005 0.01 ENST00000596853.1
ENST00000596075.1
ENST00000595992.1
ENST00000396969.4
ENST00000601533.1
ENST00000598692.1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr1_-_232651312 0.01 ENST00000262861.4
signal-induced proliferation-associated 1 like 2
chr2_+_196313239 0.01 ENST00000413290.1
AC064834.1
chr1_-_151762900 0.01 ENST00000440583.2
tudor and KH domain containing
chr4_-_39979576 0.01 ENST00000303538.8
ENST00000503396.1
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr19_+_48949030 0.01 ENST00000253237.5
glutamate-rich WD repeat containing 1
chr18_-_33709268 0.01 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
solute carrier family 39 (zinc transporter), member 6
chrX_+_154444643 0.01 ENST00000286428.5
von Hippel-Lindau binding protein 1
chr10_-_99447024 0.01 ENST00000370626.3
arginine vasopressin-induced 1
chr15_+_80351910 0.01 ENST00000261749.6
ENST00000561060.1
zinc finger, AN1-type domain 6
chrX_+_591524 0.01 ENST00000554971.1
ENST00000381575.1
short stature homeobox
chr3_-_195538728 0.01 ENST00000349607.4
ENST00000346145.4
mucin 4, cell surface associated
chr17_+_59489112 0.01 ENST00000335108.2
chromosome 17 open reading frame 82
chr19_-_40931891 0.01 ENST00000357949.4
SERTA domain containing 1
chr16_+_20911174 0.01 ENST00000568663.1
LYR motif containing 1
chr17_+_47448102 0.01 ENST00000576461.1
Uncharacterized protein
chr2_-_157189180 0.01 ENST00000539077.1
ENST00000424077.1
ENST00000426264.1
ENST00000339562.4
ENST00000421709.1
nuclear receptor subfamily 4, group A, member 2
chr12_-_121972556 0.01 ENST00000545022.1
lysine (K)-specific demethylase 2B
chr18_-_53019208 0.01 ENST00000562607.1
transcription factor 4
chr2_-_61697862 0.01 ENST00000398571.2
ubiquitin specific peptidase 34
chr8_+_92261516 0.01 ENST00000276609.3
ENST00000309536.2
solute carrier family 26 (anion exchanger), member 7
chr18_-_44181442 0.01 ENST00000398722.4
lipoxygenase homology domains 1
chr6_-_100912785 0.01 ENST00000369208.3
single-minded family bHLH transcription factor 1
chr19_-_51522955 0.01 ENST00000358789.3
kallikrein-related peptidase 10
chr4_-_36245561 0.01 ENST00000506189.1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr1_+_214161272 0.01 ENST00000498508.2
ENST00000366958.4
prospero homeobox 1
chr17_-_48785216 0.01 ENST00000285243.6
ankyrin repeat domain 40
chr20_-_50722183 0.01 ENST00000371523.4
ZFP64 zinc finger protein
chr5_-_95297678 0.01 ENST00000237853.4
elongation factor, RNA polymerase II, 2
chrX_-_21676442 0.01 ENST00000379499.2
kelch-like family member 34
chr15_+_48483736 0.01 ENST00000417307.2
ENST00000559641.1
cortexin 2
solute carrier family 12 (sodium/potassium/chloride transporter), member 1
chr2_+_86668464 0.01 ENST00000409064.1
lysine (K)-specific demethylase 3A
chr1_+_62901968 0.01 ENST00000452143.1
ENST00000442679.1
ENST00000371146.1
ubiquitin specific peptidase 1
chr5_-_10761206 0.01 ENST00000432074.2
ENST00000230895.6
death-associated protein
chr1_+_160370344 0.01 ENST00000368061.2
VANGL planar cell polarity protein 2
chr4_-_89205879 0.01 ENST00000608933.1
ENST00000315194.4
ENST00000514204.1
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr5_+_66300446 0.01 ENST00000261569.7
microtubule associated serine/threonine kinase family member 4
chr15_+_76629064 0.01 ENST00000290759.4
ISL LIM homeobox 2
chr6_-_116833500 0.01 ENST00000356128.4
trafficking protein particle complex 3-like
chr2_+_65216462 0.01 ENST00000234256.3
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr19_-_6737241 0.01 ENST00000430424.4
ENST00000597298.1
G protein-coupled receptor 108
chr4_-_89205705 0.01 ENST00000295908.7
ENST00000510548.2
ENST00000508256.1
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr15_-_31393910 0.01 ENST00000397795.2
ENST00000256552.6
ENST00000559179.1
transient receptor potential cation channel, subfamily M, member 1
chr18_+_55888767 0.01 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr6_+_43968306 0.01 ENST00000442114.2
ENST00000336600.5
ENST00000439969.2
chromosome 6 open reading frame 223
chr10_-_50970382 0.01 ENST00000419399.1
ENST00000432695.1
oxoglutarate dehydrogenase-like
chr14_-_74551172 0.01 ENST00000553458.1
aldehyde dehydrogenase 6 family, member A1
chr19_-_6737576 0.01 ENST00000601716.1
ENST00000264080.7
G protein-coupled receptor 108
chr19_+_14640372 0.01 ENST00000215567.5
ENST00000598298.1
ENST00000596073.1
ENST00000600083.1
ENST00000436007.2
trans-2,3-enoyl-CoA reductase
chr16_+_103816 0.01 ENST00000383018.3
ENST00000417493.1
small nuclear ribonucleoprotein 25kDa (U11/U12)
chr5_+_125758865 0.01 ENST00000542322.1
ENST00000544396.1
GRAM domain containing 3
chr4_-_174255400 0.01 ENST00000506267.1
high mobility group box 2
chr3_+_172468472 0.01 ENST00000232458.5
ENST00000392692.3
epithelial cell transforming sequence 2 oncogene
chr4_+_71587669 0.01 ENST00000381006.3
ENST00000226328.4
RUN and FYVE domain containing 3
chr2_+_171034646 0.01 ENST00000409044.3
ENST00000408978.4
myosin IIIB
chr19_+_49990811 0.01 ENST00000391857.4
ENST00000467825.2
ribosomal protein L13a
chr1_-_190446759 0.01 ENST00000367462.3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr9_+_1050331 0.01 ENST00000382255.3
ENST00000382251.3
ENST00000412350.2
doublesex and mab-3 related transcription factor 2
chr6_+_39760129 0.01 ENST00000274867.4
dishevelled associated activator of morphogenesis 2
chr12_-_28122980 0.01 ENST00000395868.3
ENST00000534890.1
parathyroid hormone-like hormone
chr4_+_95916947 0.01 ENST00000506363.1
bone morphogenetic protein receptor, type IB
chr12_-_16759440 0.01 ENST00000537304.1
LIM domain only 3 (rhombotin-like 2)
chr9_-_136933615 0.01 ENST00000371834.2
bromodomain containing 3
chr15_-_64673665 0.01 ENST00000300035.4
KIAA0101
chr10_-_50970322 0.01 ENST00000374103.4
oxoglutarate dehydrogenase-like
chr14_+_96000930 0.01 ENST00000331334.4
glutaredoxin 5
chr15_-_64673630 0.01 ENST00000558008.1
ENST00000559519.1
ENST00000380258.2
KIAA0101
chr3_+_111717600 0.01 ENST00000273368.4
transgelin 3
chr1_-_118472171 0.01 ENST00000369442.3
ganglioside induced differentiation associated protein 2
chr5_+_145826867 0.01 ENST00000296702.5
ENST00000394421.2
transcription elongation regulator 1
chr18_+_32173276 0.00 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
dystrobrevin, alpha
chr1_+_42846443 0.00 ENST00000410070.2
ENST00000431473.3
ribosomal modification protein rimK-like family member A
chr3_+_111717511 0.00 ENST00000478951.1
ENST00000393917.2
transgelin 3
chr5_-_95297534 0.00 ENST00000513343.1
ENST00000431061.2
elongation factor, RNA polymerase II, 2
chr11_-_71823796 0.00 ENST00000545680.1
ENST00000543587.1
ENST00000538393.1
ENST00000535234.1
ENST00000227618.4
ENST00000535503.1
anaphase promoting complex subunit 15
chr3_+_111718036 0.00 ENST00000455401.2
transgelin 3
chr11_-_71823266 0.00 ENST00000538919.1
ENST00000539395.1
ENST00000542531.1
anaphase promoting complex subunit 15
chr17_-_64225508 0.00 ENST00000205948.6
apolipoprotein H (beta-2-glycoprotein I)
chr19_-_7968427 0.00 ENST00000539278.1
Uncharacterized protein
chr5_+_125758813 0.00 ENST00000285689.3
ENST00000515200.1
GRAM domain containing 3
chr5_+_179159813 0.00 ENST00000292599.3
mastermind-like 1 (Drosophila)
chr6_-_161695074 0.00 ENST00000457520.2
ENST00000366906.5
ENST00000320285.4
1-acylglycerol-3-phosphate O-acyltransferase 4
chr1_-_156399184 0.00 ENST00000368243.1
ENST00000357975.4
ENST00000310027.5
ENST00000400991.2
chromosome 1 open reading frame 61
chrX_+_135730297 0.00 ENST00000370629.2
CD40 ligand
chr7_-_99717463 0.00 ENST00000437822.2
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr4_-_138453606 0.00 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
protocadherin 18
chr19_-_19302931 0.00 ENST00000444486.3
ENST00000514819.3
ENST00000585679.1
ENST00000162023.5
MEF2BNB-MEF2B readthrough
MEF2B neighbor
myocyte enhancer factor 2B
chr3_+_172468505 0.00 ENST00000427830.1
ENST00000417960.1
ENST00000428567.1
ENST00000366090.2
ENST00000426894.1
epithelial cell transforming sequence 2 oncogene
chrX_+_95939638 0.00 ENST00000373061.3
ENST00000373054.4
ENST00000355827.4
diaphanous-related formin 2
chr11_+_75526212 0.00 ENST00000356136.3
UV radiation resistance associated
chr9_-_136933134 0.00 ENST00000303407.7
bromodomain containing 3
chr5_+_125759140 0.00 ENST00000543198.1
GRAM domain containing 3
chr17_-_10017864 0.00 ENST00000323816.4
growth arrest-specific 7
chr14_-_73360796 0.00 ENST00000556509.1
ENST00000541685.1
ENST00000546183.1
D4, zinc and double PHD fingers, family 3
chr4_-_54232144 0.00 ENST00000388940.4
ENST00000503450.1
ENST00000401642.3
sec1 family domain containing 2
chr7_+_77428149 0.00 ENST00000415251.2
ENST00000275575.7
putative homeodomain transcription factor 2
chrX_-_53461288 0.00 ENST00000375298.4
ENST00000375304.5
hydroxysteroid (17-beta) dehydrogenase 10
chr1_-_234667504 0.00 ENST00000421207.1
ENST00000435574.1
RP5-855F14.1
chr12_+_53662110 0.00 ENST00000552462.1
extra spindle pole bodies homolog 1 (S. cerevisiae)
chr12_-_16760021 0.00 ENST00000540445.1
LIM domain only 3 (rhombotin-like 2)
chr3_-_195538760 0.00 ENST00000475231.1
mucin 4, cell surface associated
chr21_-_43816052 0.00 ENST00000398405.1
transmembrane protease, serine 3
chr5_+_141303373 0.00 ENST00000432126.2
ENST00000194118.4
KIAA0141
chr19_+_45394477 0.00 ENST00000252487.5
ENST00000405636.2
ENST00000592434.1
ENST00000426677.2
ENST00000589649.1
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr7_+_127292234 0.00 ENST00000354725.3
staphylococcal nuclease and tudor domain containing 1
chr12_-_53171128 0.00 ENST00000332411.2
keratin 76
chr10_+_99205959 0.00 ENST00000352634.4
ENST00000353979.3
ENST00000370842.2
ENST00000345745.5
zinc finger, DHHC-type containing 16
chr6_-_139613269 0.00 ENST00000358430.3
taxilin beta
chr11_-_118023490 0.00 ENST00000324727.4
sodium channel, voltage-gated, type IV, beta subunit
chr19_-_15236470 0.00 ENST00000533747.1
ENST00000598709.1
ENST00000534378.1
ilvB (bacterial acetolactate synthase)-like
chrX_+_95939711 0.00 ENST00000373049.4
ENST00000324765.8
diaphanous-related formin 2
chr3_-_157217328 0.00 ENST00000392832.2
ENST00000543418.1
ventricular zone expressed PH domain-containing 1
chr2_-_224467002 0.00 ENST00000421386.1
ENST00000433889.1
secretogranin II
chr7_-_107642348 0.00 ENST00000393561.1
laminin, beta 1
chr3_-_52090461 0.00 ENST00000296483.6
ENST00000495880.1
dual specificity phosphatase 7
chr1_-_68698197 0.00 ENST00000370973.2
ENST00000370971.1
wntless Wnt ligand secretion mediator
chr15_+_34638066 0.00 ENST00000333756.4
NUT midline carcinoma, family member 1
chr22_+_39916558 0.00 ENST00000337304.2
ENST00000396680.1
activating transcription factor 4
chr5_+_141303461 0.00 ENST00000508751.1
KIAA0141
chr4_-_186570679 0.00 ENST00000451974.1
sorbin and SH3 domain containing 2
chr12_-_16760195 0.00 ENST00000546281.1
ENST00000537757.1
LIM domain only 3 (rhombotin-like 2)
chr1_+_62439037 0.00 ENST00000545929.1
InaD-like (Drosophila)
chr12_-_14849470 0.00 ENST00000261170.3
guanylate cyclase 2C (heat stable enterotoxin receptor)
chr11_+_57435219 0.00 ENST00000527985.1
ENST00000287169.3
zinc finger, DHHC-type containing 5
chr1_+_171227069 0.00 ENST00000354841.4
flavin containing monooxygenase 1
chr6_-_167040693 0.00 ENST00000366863.2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr17_-_9929581 0.00 ENST00000437099.2
ENST00000396115.2
growth arrest-specific 7
chrM_+_9207 0.00 ENST00000362079.2
mitochondrially encoded cytochrome c oxidase III
chr12_-_16759711 0.00 ENST00000447609.1
LIM domain only 3 (rhombotin-like 2)
chr7_+_1272522 0.00 ENST00000316333.8
UNC homeobox
chr7_-_83278322 0.00 ENST00000307792.3
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr11_-_71823715 0.00 ENST00000545944.1
ENST00000502597.2
anaphase promoting complex subunit 15
chr8_+_38831683 0.00 ENST00000302495.4
HtrA serine peptidase 4
chr10_-_99205607 0.00 ENST00000477692.2
ENST00000485122.2
ENST00000370886.5
ENST00000370885.4
ENST00000370902.3
ENST00000370884.5
exosome component 1
chr10_+_99205894 0.00 ENST00000370854.3
ENST00000393760.1
ENST00000414567.1
ENST00000370846.4
zinc finger, DHHC-type containing 16
chr7_+_129984630 0.00 ENST00000355388.3
ENST00000497503.1
ENST00000463587.1
ENST00000461828.1
ENST00000494311.1
ENST00000466363.2
ENST00000485477.1
ENST00000431780.2
ENST00000474905.1
carboxypeptidase A5
chr12_+_53662073 0.00 ENST00000553219.1
ENST00000257934.4
extra spindle pole bodies homolog 1 (S. cerevisiae)

Network of associatons between targets according to the STRING database.

First level regulatory network of EN2_GBX2_LBX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.0 0.1 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)