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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for EGR3_EGR2

Z-value: 0.78

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Transcription factors associated with EGR3_EGR2

Gene Symbol Gene ID Gene Info
EGR3
ENSG00000179388.8 early growth response 3
EGR2
ENSG00000122877.9 early growth response 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EGR2hg19_v2_chr10_-_64576105_64576133-0.964.2e-02Click!
EGR3hg19_v2_chr8_-_22550815_22550844-0.772.3e-01Click!

Activity profile of EGR3_EGR2 motif

Sorted Z-values of EGR3_EGR2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_76649753 0.77 ENST00000603759.1
USO1
USO1 vesicle transport factor
chr6_+_12012170 0.51 ENST00000487103.1
HIVEP1
human immunodeficiency virus type I enhancer binding protein 1
chr19_-_49622348 0.44 ENST00000408991.2
C19orf73
chromosome 19 open reading frame 73
chr2_-_98612379 0.43 ENST00000425805.2
TMEM131
transmembrane protein 131
chr2_+_149402009 0.37 ENST00000457184.1
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr19_+_46144884 0.35 ENST00000593161.1
AC006132.1
chromosome 19 open reading frame 83
chr1_-_85156417 0.34 ENST00000422026.1
SSX2IP
synovial sarcoma, X breakpoint 2 interacting protein
chr11_+_64009072 0.32 ENST00000535135.1
ENST00000394540.3
FKBP2
FK506 binding protein 2, 13kDa
chr4_-_83295296 0.32 ENST00000507010.1
ENST00000503822.1
HNRNPD
heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
chr16_-_31021717 0.32 ENST00000565419.1
STX1B
syntaxin 1B
chr19_-_49371711 0.31 ENST00000355496.5
ENST00000263265.6
PLEKHA4
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
chr15_-_72410455 0.31 ENST00000569314.1
MYO9A
myosin IXA
chrX_-_48814810 0.31 ENST00000376488.3
ENST00000396743.3
ENST00000156084.4
OTUD5
OTU domain containing 5
chr11_+_117198801 0.30 ENST00000527609.1
ENST00000533570.1
CEP164
centrosomal protein 164kDa
chr19_-_46145696 0.29 ENST00000588172.1
EML2
echinoderm microtubule associated protein like 2
chr8_-_101322132 0.29 ENST00000523481.1
RNF19A
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr14_-_51027838 0.27 ENST00000555216.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr16_-_54962704 0.27 ENST00000502066.2
ENST00000560912.1
ENST00000558952.1
CRNDE
colorectal neoplasia differentially expressed (non-protein coding)
chr7_+_5465382 0.26 ENST00000609130.1
RP11-1275H24.2
RP11-1275H24.2
chr9_+_127020202 0.26 ENST00000373600.3
ENST00000320246.5
NEK6
NIMA-related kinase 6
chr2_+_191513789 0.26 ENST00000409581.1
NAB1
NGFI-A binding protein 1 (EGR1 binding protein 1)
chr15_-_71146460 0.25 ENST00000344870.4
LARP6
La ribonucleoprotein domain family, member 6
chr2_+_220306745 0.24 ENST00000431523.1
ENST00000396698.1
ENST00000396695.2
SPEG
SPEG complex locus
chr19_+_1261106 0.24 ENST00000588411.1
CIRBP
cold inducible RNA binding protein
chr4_-_83351294 0.23 ENST00000502762.1
HNRNPDL
heterogeneous nuclear ribonucleoprotein D-like
chr12_-_57634475 0.23 ENST00000393825.1
NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr2_+_177502438 0.22 ENST00000443670.1
AC017048.4
long intergenic non-protein coding RNA 1117
chr5_-_176924562 0.22 ENST00000359895.2
ENST00000355572.2
ENST00000355841.2
ENST00000393551.1
ENST00000505074.1
ENST00000356618.4
ENST00000393546.4
PDLIM7
PDZ and LIM domain 7 (enigma)
chr17_+_46985823 0.21 ENST00000508468.2
UBE2Z
ubiquitin-conjugating enzyme E2Z
chr15_+_76030311 0.20 ENST00000543887.1
AC019294.1
AC019294.1
chr2_-_74648702 0.20 ENST00000518863.1
C2orf81
chromosome 2 open reading frame 81
chr4_-_76649546 0.20 ENST00000508510.1
ENST00000509561.1
ENST00000499709.2
ENST00000511868.1
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr12_+_77158021 0.19 ENST00000550876.1
ZDHHC17
zinc finger, DHHC-type containing 17
chr2_-_239149300 0.19 ENST00000436051.1
HES6
hes family bHLH transcription factor 6
chr6_-_110500826 0.19 ENST00000265601.3
ENST00000447287.1
ENST00000444391.1
WASF1
WAS protein family, member 1
chr11_-_72853267 0.19 ENST00000409418.4
FCHSD2
FCH and double SH3 domains 2
chr4_-_83295103 0.18 ENST00000313899.7
ENST00000352301.4
ENST00000509107.1
ENST00000353341.4
ENST00000541060.1
HNRNPD
heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
chr9_-_14322319 0.18 ENST00000606230.1
NFIB
nuclear factor I/B
chr11_+_73498973 0.18 ENST00000537007.1
MRPL48
mitochondrial ribosomal protein L48
chr5_-_178054014 0.18 ENST00000520957.1
CLK4
CDC-like kinase 4
chr6_-_33266492 0.18 ENST00000425946.1
RGL2
ral guanine nucleotide dissociation stimulator-like 2
chr17_-_79008373 0.18 ENST00000577066.1
ENST00000573167.1
BAIAP2-AS1
BAIAP2 antisense RNA 1 (head to head)
chr1_+_23695680 0.17 ENST00000454117.1
ENST00000335648.3
ENST00000518821.1
ENST00000437367.2
C1orf213
chromosome 1 open reading frame 213
chr15_+_40733387 0.17 ENST00000416165.1
BAHD1
bromo adjacent homology domain containing 1
chr19_+_49617581 0.17 ENST00000391864.3
LIN7B
lin-7 homolog B (C. elegans)
chr19_+_10400615 0.17 ENST00000221980.4
ICAM5
intercellular adhesion molecule 5, telencephalin
chr2_+_187350973 0.17 ENST00000544130.1
ZC3H15
zinc finger CCCH-type containing 15
chr4_-_78740769 0.17 ENST00000512485.1
CNOT6L
CCR4-NOT transcription complex, subunit 6-like
chr11_-_65640071 0.16 ENST00000526624.1
EFEMP2
EGF containing fibulin-like extracellular matrix protein 2
chr7_+_151038850 0.16 ENST00000355851.4
ENST00000566856.1
ENST00000470229.1
NUB1
negative regulator of ubiquitin-like proteins 1
chr8_+_145490549 0.16 ENST00000340695.2
SCXA
scleraxis homolog A (mouse)
chr15_-_40574787 0.16 ENST00000434396.1
ANKRD63
ankyrin repeat domain 63
chr3_-_149688971 0.16 ENST00000498307.1
ENST00000489155.1
PFN2
profilin 2
chr1_-_16302608 0.16 ENST00000375743.4
ENST00000375733.2
ZBTB17
zinc finger and BTB domain containing 17
chrX_-_48814278 0.15 ENST00000455452.1
OTUD5
OTU domain containing 5
chr12_-_6715808 0.15 ENST00000545584.1
CHD4
chromodomain helicase DNA binding protein 4
chr3_+_50192833 0.14 ENST00000426511.1
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr2_+_191513959 0.14 ENST00000337386.5
ENST00000357215.5
NAB1
NGFI-A binding protein 1 (EGR1 binding protein 1)
chr4_-_36246060 0.14 ENST00000303965.4
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr3_-_171177852 0.14 ENST00000284483.8
ENST00000475336.1
ENST00000357327.5
ENST00000460047.1
ENST00000488470.1
ENST00000470834.1
TNIK
TRAF2 and NCK interacting kinase
chr19_-_14201776 0.14 ENST00000269724.5
SAMD1
sterile alpha motif domain containing 1
chr10_-_27444143 0.14 ENST00000477432.1
YME1L1
YME1-like 1 ATPase
chr17_-_4710288 0.14 ENST00000571067.1
RP11-81A22.5
RP11-81A22.5
chr1_-_197744763 0.14 ENST00000422998.1
DENND1B
DENN/MADD domain containing 1B
chr16_-_28608364 0.14 ENST00000533150.1
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr10_-_95462265 0.13 ENST00000536233.1
ENST00000359204.4
ENST00000371430.2
ENST00000394100.2
FRA10AC1
fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1
chr7_+_151038785 0.13 ENST00000413040.2
ENST00000568733.1
NUB1
negative regulator of ubiquitin-like proteins 1
chr3_+_184056614 0.13 ENST00000453072.1
FAM131A
family with sequence similarity 131, member A
chr7_+_70229899 0.13 ENST00000443672.1
AUTS2
autism susceptibility candidate 2
chr20_+_35201993 0.13 ENST00000373872.4
TGIF2
TGFB-induced factor homeobox 2
chr2_+_219724544 0.13 ENST00000233948.3
WNT6
wingless-type MMTV integration site family, member 6
chr9_+_35829208 0.13 ENST00000439587.2
ENST00000377991.4
TMEM8B
transmembrane protein 8B
chr8_-_57123815 0.13 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
PLAG1
pleiomorphic adenoma gene 1
chr6_-_31633624 0.13 ENST00000375895.2
ENST00000375900.4
GPANK1
G patch domain and ankyrin repeats 1
chr10_-_127408011 0.12 ENST00000531977.1
ENST00000527483.1
ENST00000525909.1
ENST00000528844.1
ENST00000423178.2
RP11-383C5.4
RP11-383C5.4
chrX_+_155227371 0.12 ENST00000369423.2
ENST00000540897.1
IL9R
interleukin 9 receptor
chr19_-_663147 0.12 ENST00000606702.1
RNF126
ring finger protein 126
chrX_-_19905577 0.12 ENST00000379697.3
SH3KBP1
SH3-domain kinase binding protein 1
chr4_+_26859300 0.12 ENST00000494628.2
STIM2
stromal interaction molecule 2
chr1_+_145726886 0.12 ENST00000443667.1
PDZK1
PDZ domain containing 1
chrX_+_155227246 0.12 ENST00000244174.5
ENST00000424344.3
IL9R
interleukin 9 receptor
chr10_-_18948208 0.12 ENST00000607346.1
ARL5B-AS1
ARL5B antisense RNA 1
chr16_-_850723 0.12 ENST00000248150.4
GNG13
guanine nucleotide binding protein (G protein), gamma 13
chr11_+_114310164 0.12 ENST00000544196.1
ENST00000539754.1
ENST00000539275.1
REXO2
RNA exonuclease 2
chr14_+_21566980 0.12 ENST00000418511.2
ENST00000554329.2
TMEM253
transmembrane protein 253
chr20_+_2673383 0.12 ENST00000380648.4
ENST00000342725.5
EBF4
early B-cell factor 4
chr12_+_69864129 0.12 ENST00000547219.1
ENST00000299293.2
ENST00000549921.1
ENST00000550316.1
ENST00000548154.1
ENST00000547414.1
ENST00000550389.1
ENST00000550937.1
ENST00000549092.1
ENST00000550169.1
FRS2
fibroblast growth factor receptor substrate 2
chr17_-_73178599 0.12 ENST00000578238.1
SUMO2
small ubiquitin-like modifier 2
chr17_+_36858694 0.12 ENST00000563897.1
CTB-58E17.1
CTB-58E17.1
chr3_-_88108212 0.11 ENST00000482016.1
CGGBP1
CGG triplet repeat binding protein 1
chr3_-_135915146 0.11 ENST00000473093.1
MSL2
male-specific lethal 2 homolog (Drosophila)
chr6_-_42110342 0.11 ENST00000356542.5
C6orf132
chromosome 6 open reading frame 132
chr12_+_70760056 0.11 ENST00000258111.4
KCNMB4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr6_+_134274354 0.11 ENST00000367869.1
TBPL1
TBP-like 1
chr3_-_113415441 0.11 ENST00000491165.1
ENST00000316407.4
KIAA2018
KIAA2018
chr5_-_142784101 0.11 ENST00000503201.1
ENST00000502892.1
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr14_+_91526668 0.11 ENST00000521334.1
C14orf159
chromosome 14 open reading frame 159
chr4_+_38869298 0.11 ENST00000510213.1
ENST00000515037.1
FAM114A1
family with sequence similarity 114, member A1
chr2_+_105953972 0.11 ENST00000410049.1
C2orf49
chromosome 2 open reading frame 49
chr3_-_171178157 0.11 ENST00000465393.1
ENST00000436636.2
ENST00000369326.5
ENST00000538048.1
ENST00000341852.6
TNIK
TRAF2 and NCK interacting kinase
chr12_-_105352047 0.11 ENST00000432951.1
ENST00000415674.1
ENST00000424946.1
SLC41A2
solute carrier family 41 (magnesium transporter), member 2
chr9_-_15510287 0.11 ENST00000397519.2
PSIP1
PC4 and SFRS1 interacting protein 1
chr19_+_11457232 0.11 ENST00000587531.1
CCDC159
coiled-coil domain containing 159
chr17_-_4890919 0.11 ENST00000572543.1
ENST00000381311.5
ENST00000348066.3
ENST00000358183.4
CAMTA2
calmodulin binding transcription activator 2
chrX_-_47509994 0.11 ENST00000343894.4
ELK1
ELK1, member of ETS oncogene family
chr17_-_62502399 0.11 ENST00000450599.2
ENST00000585060.1
DDX5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr9_-_101017900 0.10 ENST00000375066.5
TBC1D2
TBC1 domain family, member 2
chr11_+_8704748 0.10 ENST00000526562.1
ENST00000525981.1
RPL27A
ribosomal protein L27a
chr15_-_34502197 0.10 ENST00000557877.1
KATNBL1
katanin p80 subunit B-like 1
chr11_-_110167331 0.10 ENST00000534683.1
RDX
radixin
chr2_+_233562015 0.10 ENST00000427233.1
ENST00000373566.3
ENST00000373563.4
ENST00000428883.1
ENST00000456491.1
ENST00000409480.1
ENST00000421433.1
ENST00000425040.1
ENST00000430720.1
ENST00000409547.1
ENST00000423659.1
ENST00000409196.3
ENST00000409451.3
ENST00000429187.1
ENST00000440945.1
GIGYF2
GRB10 interacting GYF protein 2
chr1_-_23670752 0.10 ENST00000302271.6
ENST00000426846.2
ENST00000427764.2
ENST00000606561.1
ENST00000374616.3
HNRNPR
heterogeneous nuclear ribonucleoprotein R
chr6_-_110501126 0.10 ENST00000368938.1
WASF1
WAS protein family, member 1
chr6_-_32157947 0.10 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr15_-_45480153 0.10 ENST00000560471.1
ENST00000560540.1
SHF
Src homology 2 domain containing F
chrX_-_49056635 0.10 ENST00000472598.1
ENST00000538567.1
ENST00000479808.1
ENST00000263233.4
SYP
synaptophysin
chr2_+_111878483 0.10 ENST00000308659.8
ENST00000357757.2
ENST00000393253.2
ENST00000337565.5
ENST00000393256.3
BCL2L11
BCL2-like 11 (apoptosis facilitator)
chr15_-_89089860 0.10 ENST00000558413.1
ENST00000564406.1
ENST00000268148.8
DET1
de-etiolated homolog 1 (Arabidopsis)
chr6_-_31088214 0.10 ENST00000376288.2
CDSN
corneodesmosin
chr2_-_48132814 0.10 ENST00000316377.4
ENST00000378314.3
FBXO11
F-box protein 11
chr15_-_42783303 0.10 ENST00000565380.1
ENST00000564754.1
ZNF106
zinc finger protein 106
chr13_-_52026730 0.10 ENST00000420668.2
INTS6
integrator complex subunit 6
chr19_-_38878632 0.10 ENST00000586599.1
ENST00000334928.6
ENST00000587676.1
GGN
gametogenetin
chr10_+_91461413 0.09 ENST00000447580.1
KIF20B
kinesin family member 20B
chr7_+_90032821 0.09 ENST00000427904.1
CLDN12
claudin 12
chr7_-_43909090 0.09 ENST00000317534.5
MRPS24
mitochondrial ribosomal protein S24
chrX_-_128788914 0.09 ENST00000429967.1
ENST00000307484.6
APLN
apelin
chr10_+_114709999 0.09 ENST00000355995.4
ENST00000545257.1
ENST00000543371.1
ENST00000536810.1
ENST00000355717.4
ENST00000538897.1
ENST00000534894.1
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr20_-_4229721 0.09 ENST00000379453.4
ADRA1D
adrenoceptor alpha 1D
chr9_+_96338860 0.09 ENST00000375376.4
PHF2
PHD finger protein 2
chr16_-_67969888 0.09 ENST00000574576.2
PSMB10
proteasome (prosome, macropain) subunit, beta type, 10
chr15_+_52311398 0.09 ENST00000261845.5
MAPK6
mitogen-activated protein kinase 6
chr6_+_2245982 0.09 ENST00000530346.1
ENST00000524770.1
ENST00000532124.1
ENST00000531092.1
ENST00000456943.2
ENST00000529893.1
GMDS-AS1
GMDS antisense RNA 1 (head to head)
chr17_+_20059358 0.09 ENST00000536879.1
ENST00000395522.2
ENST00000395525.3
SPECC1
sperm antigen with calponin homology and coiled-coil domains 1
chr2_-_222436988 0.09 ENST00000409854.1
ENST00000281821.2
ENST00000392071.4
ENST00000443796.1
EPHA4
EPH receptor A4
chr9_+_108210279 0.09 ENST00000374716.4
ENST00000374710.3
ENST00000481272.1
ENST00000484973.1
ENST00000394926.3
ENST00000539376.1
FSD1L
fibronectin type III and SPRY domain containing 1-like
chr16_+_2286726 0.09 ENST00000382437.4
ENST00000569184.1
DNASE1L2
deoxyribonuclease I-like 2
chr17_-_4890649 0.09 ENST00000361571.5
CAMTA2
calmodulin binding transcription activator 2
chr11_+_8704298 0.09 ENST00000531978.1
ENST00000524496.1
ENST00000532359.1
ENST00000530022.1
RPL27A
ribosomal protein L27a
chr9_+_127020503 0.09 ENST00000545174.1
ENST00000444973.1
ENST00000454453.1
NEK6
NIMA-related kinase 6
chr1_+_178994939 0.09 ENST00000440702.1
FAM20B
family with sequence similarity 20, member B
chr22_+_36784632 0.09 ENST00000424761.1
RP4-633O19__A.1
RP4-633O19__A.1
chr8_+_26149274 0.09 ENST00000522535.1
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr6_-_37665751 0.09 ENST00000297153.7
ENST00000434837.3
MDGA1
MAM domain containing glycosylphosphatidylinositol anchor 1
chr3_-_52002194 0.09 ENST00000466412.1
PCBP4
poly(rC) binding protein 4
chr13_-_52027134 0.09 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6
integrator complex subunit 6
chr9_-_132597529 0.08 ENST00000372447.3
C9orf78
chromosome 9 open reading frame 78
chr19_+_44037546 0.08 ENST00000601282.1
ZNF575
zinc finger protein 575
chr7_-_100808843 0.08 ENST00000249330.2
VGF
VGF nerve growth factor inducible
chr17_+_44668387 0.08 ENST00000576040.1
NSF
N-ethylmaleimide-sensitive factor
chrX_+_117480036 0.08 ENST00000371822.5
ENST00000254029.3
ENST00000371825.3
WDR44
WD repeat domain 44
chr10_+_22614547 0.08 ENST00000416820.1
BMI1
BMI1 polycomb ring finger oncogene
chr5_-_133706695 0.08 ENST00000521755.1
ENST00000523054.1
ENST00000435240.2
ENST00000609654.1
ENST00000536186.1
ENST00000609383.1
CDKL3
cyclin-dependent kinase-like 3
chr15_-_72410109 0.08 ENST00000564571.1
MYO9A
myosin IXA
chr8_-_27469383 0.08 ENST00000519742.1
CLU
clusterin
chr14_+_66974845 0.08 ENST00000459628.1
GPHN
gephyrin
chr15_-_83316711 0.08 ENST00000568128.1
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr14_-_75079294 0.08 ENST00000556359.1
LTBP2
latent transforming growth factor beta binding protein 2
chr16_-_54320675 0.08 ENST00000329734.3
IRX3
iroquois homeobox 3
chr17_+_57697246 0.08 ENST00000580081.1
ENST00000579456.1
CLTC
clathrin, heavy chain (Hc)
chr7_-_27213893 0.08 ENST00000283921.4
HOXA10
homeobox A10
chr11_+_114310237 0.08 ENST00000539119.1
REXO2
RNA exonuclease 2
chr1_-_67896009 0.08 ENST00000370990.5
SERBP1
SERPINE1 mRNA binding protein 1
chr8_+_109455830 0.08 ENST00000524143.1
EMC2
ER membrane protein complex subunit 2
chr19_+_44037334 0.08 ENST00000314228.5
ZNF575
zinc finger protein 575
chr14_+_70234642 0.08 ENST00000555349.1
ENST00000554021.1
SRSF5
serine/arginine-rich splicing factor 5
chr13_-_45915221 0.08 ENST00000309246.5
ENST00000379060.4
ENST00000379055.1
ENST00000527226.1
ENST00000379056.1
TPT1
tumor protein, translationally-controlled 1
chr19_-_33793430 0.08 ENST00000498907.2
CEBPA
CCAAT/enhancer binding protein (C/EBP), alpha
chr19_-_37096139 0.08 ENST00000585983.1
ENST00000585960.1
ENST00000586115.1
ZNF529
zinc finger protein 529
chr12_+_75728419 0.08 ENST00000378695.4
ENST00000312442.2
GLIPR1L1
GLI pathogenesis-related 1 like 1
chr19_-_15311713 0.08 ENST00000601011.1
ENST00000263388.2
NOTCH3
notch 3
chr5_-_176923803 0.08 ENST00000506161.1
PDLIM7
PDZ and LIM domain 7 (enigma)
chr6_-_166401442 0.08 ENST00000584179.1
LINC00473
long intergenic non-protein coding RNA 473
chr6_-_46620522 0.08 ENST00000275016.2
CYP39A1
cytochrome P450, family 39, subfamily A, polypeptide 1
chr11_+_61891445 0.08 ENST00000394818.3
ENST00000533896.1
ENST00000278849.4
INCENP
inner centromere protein antigens 135/155kDa
chr17_-_62502639 0.08 ENST00000225792.5
ENST00000581697.1
ENST00000584279.1
ENST00000577922.1
DDX5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr7_+_43803790 0.08 ENST00000424330.1
BLVRA
biliverdin reductase A
chr10_-_32217717 0.08 ENST00000396144.4
ENST00000375245.4
ENST00000344936.2
ENST00000375250.5
ARHGAP12
Rho GTPase activating protein 12
chr13_+_111365602 0.08 ENST00000333219.7
ING1
inhibitor of growth family, member 1
chr1_-_180991978 0.08 ENST00000542060.1
ENST00000258301.5
STX6
syntaxin 6
chr19_+_18794470 0.08 ENST00000321949.8
ENST00000338797.6
CRTC1
CREB regulated transcription coactivator 1
chr16_-_28621298 0.08 ENST00000566189.1
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr11_-_75921780 0.08 ENST00000529461.1
WNT11
wingless-type MMTV integration site family, member 11
chr5_+_135468516 0.07 ENST00000507118.1
ENST00000511116.1
ENST00000545279.1
ENST00000545620.1
SMAD5
SMAD family member 5
chr11_+_101918153 0.07 ENST00000434758.2
ENST00000526781.1
ENST00000534360.1
C11orf70
chromosome 11 open reading frame 70
chr16_+_3070356 0.07 ENST00000341627.5
ENST00000575124.1
ENST00000575836.1
TNFRSF12A
tumor necrosis factor receptor superfamily, member 12A
chr8_-_57233103 0.07 ENST00000303749.3
ENST00000522671.1
SDR16C5
short chain dehydrogenase/reductase family 16C, member 5
chr21_+_35014706 0.07 ENST00000399353.1
ENST00000444491.1
ENST00000381318.3
ITSN1
intersectin 1 (SH3 domain protein)
chr19_-_51568324 0.07 ENST00000595547.1
ENST00000335422.3
ENST00000595793.1
ENST00000596955.1
KLK13
kallikrein-related peptidase 13
chr4_+_76649797 0.07 ENST00000538159.1
ENST00000514213.2
USO1
USO1 vesicle transport factor
chr11_-_65363259 0.07 ENST00000342202.4
KCNK7
potassium channel, subfamily K, member 7
chr5_+_67584174 0.07 ENST00000320694.8
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr7_-_100808394 0.07 ENST00000445482.2
VGF
VGF nerve growth factor inducible
chr14_-_69658127 0.07 ENST00000556182.1
RP11-363J20.1
RP11-363J20.1
chr5_-_16936340 0.07 ENST00000507288.1
ENST00000513610.1
MYO10
myosin X
chr19_+_55795493 0.07 ENST00000309383.1
BRSK1
BR serine/threonine kinase 1
chr19_-_10530784 0.07 ENST00000593124.1
CDC37
cell division cycle 37
chr6_+_133562472 0.07 ENST00000430974.2
ENST00000367895.5
ENST00000355167.3
ENST00000355286.6
EYA4
eyes absent homolog 4 (Drosophila)
chr9_+_116172958 0.07 ENST00000374165.1
C9orf43
chromosome 9 open reading frame 43
chr15_-_43785274 0.07 ENST00000413546.1
TP53BP1
tumor protein p53 binding protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of EGR3_EGR2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:1904586 response to putrescine(GO:1904585) cellular response to putrescine(GO:1904586) hepatocyte dedifferentiation(GO:1990828)
0.1 0.3 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
0.1 0.8 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.2 GO:0003335 corneocyte development(GO:0003335)
0.0 0.1 GO:1902230 regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902229) negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 0.1 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.0 0.2 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.0 0.3 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0035750 protein localization to myelin sheath abaxonal region(GO:0035750)
0.0 0.1 GO:0071629 cytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071629)
0.0 0.1 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.0 0.1 GO:0060139 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.0 0.1 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.0 GO:0045799 positive regulation of chromatin assembly or disassembly(GO:0045799)
0.0 0.2 GO:0071104 response to interleukin-9(GO:0071104)
0.0 0.1 GO:0043396 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.0 0.1 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.0 0.0 GO:0042446 hormone biosynthetic process(GO:0042446)
0.0 0.2 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:0072081 proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081)
0.0 0.1 GO:0072302 posterior mesonephric tubule development(GO:0072166) negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.0 0.2 GO:0072553 terminal button organization(GO:0072553)
0.0 0.1 GO:0033058 directional locomotion(GO:0033058)
0.0 0.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.0 GO:0021769 orbitofrontal cortex development(GO:0021769)
0.0 0.2 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.1 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.1 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.0 0.1 GO:0060584 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0 0.1 GO:2001112 negative regulation of hepatocyte growth factor receptor signaling pathway(GO:1902203) regulation of cellular response to hepatocyte growth factor stimulus(GO:2001112) negative regulation of cellular response to hepatocyte growth factor stimulus(GO:2001113)
0.0 0.2 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.1 GO:1901207 regulation of heart looping(GO:1901207)
0.0 0.3 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.1 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.1 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.3 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0030573 bile acid catabolic process(GO:0030573)
0.0 0.1 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.0 0.1 GO:1903438 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.0 0.1 GO:2000417 negative regulation of eosinophil migration(GO:2000417)
0.0 0.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.1 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.0 0.1 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.0 0.1 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398)
0.0 0.1 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.0 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.1 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.1 GO:0017198 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.0 0.1 GO:1904798 positive regulation of core promoter binding(GO:1904798)
0.0 0.0 GO:0072720 response to dithiothreitol(GO:0072720)
0.0 0.1 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.1 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.0 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
0.0 0.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.3 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.2 GO:1901166 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.0 0.1 GO:0006235 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.0 0.1 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.4 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.3 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.1 GO:0034670 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.1 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.0 0.0 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.0 0.0 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.0 0.0 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.0 0.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.0 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.0 0.1 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.1 GO:0072287 metanephric distal tubule morphogenesis(GO:0072287)
0.0 0.0 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.0 0.1 GO:0006850 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.0 0.0 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.0 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0 0.2 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.0 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0 0.1 GO:0061188 negative regulation of chromatin silencing at rDNA(GO:0061188)
0.0 0.2 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.0 0.1 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.0 GO:0044691 tooth eruption(GO:0044691)
0.0 0.0 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.0 0.0 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.0 GO:2000543 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) positive regulation of gastrulation(GO:2000543)
0.0 0.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.1 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.1 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.1 GO:0061511 centriole elongation(GO:0061511)
0.0 0.1 GO:0097435 fibril organization(GO:0097435)
0.0 0.0 GO:0015993 L-ascorbic acid transport(GO:0015882) molecular hydrogen transport(GO:0015993) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.1 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.0 0.0 GO:0042040 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.0 0.0 GO:1903565 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.0 0.0 GO:0097198 cell migration involved in vasculogenesis(GO:0035441) histone H3-K36 trimethylation(GO:0097198)
0.0 0.0 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.0 GO:1902232 regulation of positive thymic T cell selection(GO:1902232)
0.0 0.1 GO:0021592 fourth ventricle development(GO:0021592)
0.0 0.3 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.1 GO:0060509 Type I pneumocyte differentiation(GO:0060509)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.5 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369) beta-catenin-TCF complex(GO:1990907)
0.0 0.3 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.0 GO:0075341 host cell PML body(GO:0075341)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.1 GO:0097513 myosin II filament(GO:0097513)
0.0 0.1 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.1 GO:0051286 cell tip(GO:0051286)
0.0 0.1 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.1 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 0.1 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.1 GO:0002133 polycystin complex(GO:0002133)
0.0 0.1 GO:0043219 lateral loop(GO:0043219)
0.0 0.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.5 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.1 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.0 0.4 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0005124 scavenger receptor binding(GO:0005124)
0.0 0.4 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.2 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.3 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.2 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.1 GO:0031705 bombesin receptor binding(GO:0031705)
0.0 0.5 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.1 GO:0004074 biliverdin reductase activity(GO:0004074)
0.0 0.1 GO:0001147 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.1 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.0 0.1 GO:0017130 poly(C) RNA binding(GO:0017130)
0.0 0.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.0 0.1 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.0 0.1 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.0 0.0 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.0 0.0 GO:0050405 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.0 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.2 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 0.0 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.0 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.0 0.0 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.0 GO:0019150 D-ribulokinase activity(GO:0019150)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.0 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.0 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.0 GO:0061598 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.0 0.2 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.2 GO:0045499 chemorepellent activity(GO:0045499)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.7 PID ARF 3PATHWAY Arf1 pathway
0.0 0.0 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.1 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)