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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for E2F8

Z-value: 0.84

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Transcription factors associated with E2F8

Gene Symbol Gene ID Gene Info
E2F8
ENSG00000129173.8 E2F transcription factor 8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2F8hg19_v2_chr11_-_19262486_192625120.991.4e-02Click!

Activity profile of E2F8 motif

Sorted Z-values of E2F8 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_24346218 0.52 ENST00000436622.1
ENST00000313213.4
PFN4
profilin family, member 4
chr2_+_24346324 0.51 ENST00000407625.1
ENST00000420135.2
FAM228B
family with sequence similarity 228, member B
chrX_+_150866779 0.44 ENST00000370353.3
PRRG3
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chr6_+_135502501 0.42 ENST00000527615.1
ENST00000420123.2
ENST00000525369.1
ENST00000528774.1
ENST00000534121.1
ENST00000534044.1
ENST00000533624.1
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr17_+_73028676 0.34 ENST00000581589.1
KCTD2
potassium channel tetramerization domain containing 2
chr1_-_43638168 0.30 ENST00000431635.2
EBNA1BP2
EBNA1 binding protein 2
chr1_-_91328477 0.30 ENST00000606898.1
RP4-665J23.4
RP4-665J23.4
chr11_+_17298297 0.29 ENST00000529010.1
NUCB2
nucleobindin 2
chr8_-_92053042 0.29 ENST00000520014.1
TMEM55A
transmembrane protein 55A
chr4_-_39367949 0.28 ENST00000503784.1
ENST00000349703.2
ENST00000381897.1
RFC1
replication factor C (activator 1) 1, 145kDa
chr14_+_36295638 0.27 ENST00000543183.1
BRMS1L
breast cancer metastasis-suppressor 1-like
chr12_+_107168342 0.27 ENST00000392837.4
RIC8B
RIC8 guanine nucleotide exchange factor B
chr12_-_123011476 0.26 ENST00000528279.1
ENST00000344591.4
ENST00000526560.2
RSRC2
arginine/serine-rich coiled-coil 2
chr1_-_150693318 0.26 ENST00000442853.1
ENST00000368995.4
ENST00000368993.2
ENST00000361824.2
ENST00000322343.7
HORMAD1
HORMA domain containing 1
chr8_+_22411931 0.26 ENST00000523402.1
SORBS3
sorbin and SH3 domain containing 3
chr12_-_57146095 0.26 ENST00000550770.1
ENST00000338193.6
PRIM1
primase, DNA, polypeptide 1 (49kDa)
chr3_-_57113281 0.25 ENST00000468466.1
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr12_+_107168418 0.25 ENST00000392839.2
ENST00000548914.1
ENST00000355478.2
ENST00000552619.1
ENST00000549643.1
RIC8B
RIC8 guanine nucleotide exchange factor B
chr1_-_43637915 0.24 ENST00000236051.2
EBNA1BP2
EBNA1 binding protein 2
chr19_-_44172467 0.24 ENST00000599892.1
PLAUR
plasminogen activator, urokinase receptor
chr20_-_524362 0.23 ENST00000460062.2
ENST00000608066.1
CSNK2A1
casein kinase 2, alpha 1 polypeptide
chr8_+_29953163 0.23 ENST00000518192.1
LEPROTL1
leptin receptor overlapping transcript-like 1
chr17_-_62499334 0.23 ENST00000579996.1
DDX5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr4_-_174255400 0.23 ENST00000506267.1
HMGB2
high mobility group box 2
chr21_+_37477164 0.23 ENST00000422473.1
AP000688.29
AP000688.29
chr1_-_26232522 0.23 ENST00000399728.1
STMN1
stathmin 1
chr8_+_29952914 0.22 ENST00000321250.8
ENST00000518001.1
ENST00000520682.1
ENST00000442880.2
ENST00000523116.1
LEPROTL1
leptin receptor overlapping transcript-like 1
chr5_-_145483932 0.22 ENST00000311450.4
PLAC8L1
PLAC8-like 1
chr6_-_153323801 0.22 ENST00000367233.5
ENST00000367231.5
ENST00000367230.1
MTRF1L
mitochondrial translational release factor 1-like
chr3_-_25824925 0.21 ENST00000396649.3
ENST00000428257.1
ENST00000280700.5
NGLY1
N-glycanase 1
chr20_-_524340 0.21 ENST00000400227.3
CSNK2A1
casein kinase 2, alpha 1 polypeptide
chr12_-_102455846 0.21 ENST00000545679.1
CCDC53
coiled-coil domain containing 53
chr14_+_45553296 0.21 ENST00000355765.6
ENST00000553605.1
PRPF39
pre-mRNA processing factor 39
chr7_+_128379449 0.21 ENST00000479257.1
CALU
calumenin
chr15_-_40074996 0.20 ENST00000350221.3
FSIP1
fibrous sheath interacting protein 1
chr3_+_44803322 0.20 ENST00000481166.2
KIF15
kinesin family member 15
chr8_-_112248400 0.20 ENST00000519506.1
ENST00000522778.1
RP11-946L20.4
RP11-946L20.4
chr8_-_131455835 0.20 ENST00000518721.1
ASAP1
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chr3_+_14989186 0.20 ENST00000435454.1
ENST00000323373.6
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr6_+_144164455 0.20 ENST00000367576.5
LTV1
LTV1 homolog (S. cerevisiae)
chr4_-_174254823 0.20 ENST00000438704.2
HMGB2
high mobility group box 2
chr11_+_9595180 0.20 ENST00000450114.2
WEE1
WEE1 G2 checkpoint kinase
chr13_+_19756173 0.20 ENST00000382988.2
RP11-408E5.4
RP11-408E5.4
chr2_-_37193606 0.20 ENST00000379213.2
ENST00000263918.4
STRN
striatin, calmodulin binding protein
chr3_-_128902729 0.20 ENST00000451728.2
ENST00000446936.2
ENST00000502976.1
ENST00000500450.2
ENST00000441626.2
CNBP
CCHC-type zinc finger, nucleic acid binding protein
chr1_+_197871854 0.19 ENST00000436652.1
C1orf53
chromosome 1 open reading frame 53
chr20_+_18447771 0.19 ENST00000377603.4
POLR3F
polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
chr1_+_150245099 0.19 ENST00000369099.3
C1orf54
chromosome 1 open reading frame 54
chr11_+_17298255 0.19 ENST00000531172.1
ENST00000533738.2
ENST00000323688.6
NUCB2
nucleobindin 2
chr16_+_58074069 0.19 ENST00000570065.1
MMP15
matrix metallopeptidase 15 (membrane-inserted)
chr12_-_110939870 0.18 ENST00000447578.2
ENST00000546588.1
ENST00000360579.7
ENST00000549970.1
ENST00000549578.1
VPS29
vacuolar protein sorting 29 homolog (S. cerevisiae)
chrX_-_130037162 0.18 ENST00000432489.1
ENOX2
ecto-NOX disulfide-thiol exchanger 2
chr8_+_67687413 0.18 ENST00000521960.1
ENST00000522398.1
ENST00000522629.1
ENST00000520976.1
ENST00000396596.1
SGK3
serum/glucocorticoid regulated kinase family, member 3
chr9_-_123639304 0.18 ENST00000436309.1
PHF19
PHD finger protein 19
chr1_+_89150245 0.18 ENST00000370513.5
PKN2
protein kinase N2
chr1_+_170501270 0.18 ENST00000367763.3
ENST00000367762.1
GORAB
golgin, RAB6-interacting
chr3_+_122296465 0.17 ENST00000483793.1
PARP15
poly (ADP-ribose) polymerase family, member 15
chr1_+_244998918 0.17 ENST00000366528.3
COX20
COX20 cytochrome C oxidase assembly factor
chr4_+_128702969 0.17 ENST00000508776.1
ENST00000439123.2
HSPA4L
heat shock 70kDa protein 4-like
chr7_+_114562909 0.17 ENST00000423503.1
ENST00000427207.1
MDFIC
MyoD family inhibitor domain containing
chr22_+_20105012 0.17 ENST00000331821.3
ENST00000411892.1
RANBP1
RAN binding protein 1
chr10_-_95360983 0.17 ENST00000371464.3
RBP4
retinol binding protein 4, plasma
chr7_+_116593536 0.17 ENST00000417919.1
ST7
suppression of tumorigenicity 7
chrX_+_131157322 0.17 ENST00000481105.1
ENST00000354719.6
ENST00000394335.2
MST4
Serine/threonine-protein kinase MST4
chr7_+_116593568 0.17 ENST00000446490.1
ST7
suppression of tumorigenicity 7
chr22_+_29999647 0.17 ENST00000334961.7
ENST00000353887.4
NF2
neurofibromin 2 (merlin)
chr5_+_10441970 0.17 ENST00000274134.4
ROPN1L
rhophilin associated tail protein 1-like
chr17_+_42733730 0.16 ENST00000359945.3
ENST00000425535.1
C17orf104
chromosome 17 open reading frame 104
chr20_-_18447667 0.16 ENST00000262547.5
ENST00000329494.5
ENST00000357236.4
DZANK1
double zinc ribbon and ankyrin repeat domains 1
chr15_-_93965805 0.16 ENST00000556708.1
RP11-164C12.2
RP11-164C12.2
chr9_+_129097479 0.16 ENST00000402437.2
MVB12B
multivesicular body subunit 12B
chr4_-_84035905 0.16 ENST00000311507.4
PLAC8
placenta-specific 8
chr11_-_19263145 0.15 ENST00000532666.1
ENST00000527884.1
E2F8
E2F transcription factor 8
chr22_+_20105259 0.15 ENST00000416427.1
ENST00000421656.1
ENST00000423859.1
ENST00000418705.2
RANBP1
RAN binding protein 1
chr1_+_70876891 0.15 ENST00000411986.2
CTH
cystathionase (cystathionine gamma-lyase)
chr6_+_154360616 0.15 ENST00000229768.5
ENST00000419506.2
ENST00000524163.1
ENST00000414028.2
ENST00000435918.2
ENST00000337049.4
OPRM1
opioid receptor, mu 1
chr2_-_63815628 0.15 ENST00000409562.3
WDPCP
WD repeat containing planar cell polarity effector
chr1_+_70876926 0.15 ENST00000370938.3
ENST00000346806.2
CTH
cystathionase (cystathionine gamma-lyase)
chr17_+_42733803 0.15 ENST00000409122.2
C17orf104
chromosome 17 open reading frame 104
chr22_+_20104947 0.15 ENST00000402752.1
RANBP1
RAN binding protein 1
chr2_+_201242715 0.15 ENST00000421573.1
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr4_-_129209221 0.15 ENST00000512483.1
PGRMC2
progesterone receptor membrane component 2
chr10_-_46167722 0.15 ENST00000374366.3
ENST00000344646.5
ZFAND4
zinc finger, AN1-type domain 4
chr15_-_25684110 0.15 ENST00000232165.3
UBE3A
ubiquitin protein ligase E3A
chrX_+_131157290 0.15 ENST00000394334.2
MST4
Serine/threonine-protein kinase MST4
chr11_+_35201826 0.15 ENST00000531873.1
CD44
CD44 molecule (Indian blood group)
chr12_-_48499591 0.15 ENST00000551330.1
ENST00000004980.5
ENST00000339976.6
ENST00000448372.1
SENP1
SUMO1/sentrin specific peptidase 1
chr1_-_111682662 0.15 ENST00000286692.4
DRAM2
DNA-damage regulated autophagy modulator 2
chr12_-_102455902 0.15 ENST00000240079.6
CCDC53
coiled-coil domain containing 53
chr2_+_201242941 0.14 ENST00000449647.1
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr19_-_17559376 0.14 ENST00000341130.5
TMEM221
transmembrane protein 221
chr2_-_215674374 0.14 ENST00000449967.2
ENST00000421162.1
ENST00000260947.4
BARD1
BRCA1 associated RING domain 1
chr10_+_35416223 0.14 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
CREM
cAMP responsive element modulator
chr14_-_69619291 0.14 ENST00000554215.1
ENST00000556847.1
DCAF5
DDB1 and CUL4 associated factor 5
chr14_+_55595762 0.14 ENST00000254301.9
LGALS3
lectin, galactoside-binding, soluble, 3
chr9_+_79792410 0.14 ENST00000357409.5
VPS13A
vacuolar protein sorting 13 homolog A (S. cerevisiae)
chr1_-_89458287 0.14 ENST00000370485.2
CCBL2
cysteine conjugate-beta lyase 2
chr15_-_57025759 0.14 ENST00000267807.7
ZNF280D
zinc finger protein 280D
chr4_+_40058411 0.14 ENST00000261435.6
ENST00000515550.1
N4BP2
NEDD4 binding protein 2
chr1_+_48688357 0.14 ENST00000533824.1
ENST00000438567.2
ENST00000236495.5
ENST00000420136.2
SLC5A9
solute carrier family 5 (sodium/sugar cotransporter), member 9
chr6_-_57086200 0.14 ENST00000468148.1
RAB23
RAB23, member RAS oncogene family
chr12_-_46662888 0.14 ENST00000546893.1
SLC38A1
solute carrier family 38, member 1
chr4_+_25378826 0.14 ENST00000315368.3
ANAPC4
anaphase promoting complex subunit 4
chrX_-_53449593 0.14 ENST00000375340.6
ENST00000322213.4
SMC1A
structural maintenance of chromosomes 1A
chr4_-_1713977 0.14 ENST00000318386.4
SLBP
stem-loop binding protein
chr11_-_32816156 0.14 ENST00000531481.1
ENST00000335185.5
CCDC73
coiled-coil domain containing 73
chr4_-_1714037 0.14 ENST00000488267.1
ENST00000429429.2
ENST00000480936.1
SLBP
stem-loop binding protein
chr2_-_139537918 0.14 ENST00000272641.3
NXPH2
neurexophilin 2
chrX_-_130037198 0.14 ENST00000370935.1
ENST00000338144.3
ENST00000394363.1
ENOX2
ecto-NOX disulfide-thiol exchanger 2
chr4_-_4543700 0.14 ENST00000505286.1
ENST00000306200.2
STX18
syntaxin 18
chr4_+_113558272 0.14 ENST00000509061.1
ENST00000508577.1
ENST00000513553.1
LARP7
La ribonucleoprotein domain family, member 7
chr16_-_66864806 0.14 ENST00000566336.1
ENST00000394074.2
ENST00000563185.2
ENST00000359087.4
ENST00000379463.2
ENST00000565535.1
ENST00000290810.3
NAE1
NEDD8 activating enzyme E1 subunit 1
chr1_-_28241024 0.14 ENST00000313433.7
ENST00000444045.1
RPA2
replication protein A2, 32kDa
chr15_+_44719970 0.14 ENST00000558966.1
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr15_-_100258029 0.14 ENST00000378904.2
DKFZP779J2370
DKFZP779J2370
chr11_-_19262486 0.14 ENST00000250024.4
E2F8
E2F transcription factor 8
chr6_-_2962331 0.13 ENST00000380524.1
SERPINB6
serpin peptidase inhibitor, clade B (ovalbumin), member 6
chr2_+_132233664 0.13 ENST00000321253.6
TUBA3D
tubulin, alpha 3d
chr6_+_33551515 0.13 ENST00000374458.1
GGNBP1
gametogenetin binding protein 1 (pseudogene)
chr17_+_66243715 0.13 ENST00000359904.3
AMZ2
archaelysin family metallopeptidase 2
chrX_+_133371077 0.13 ENST00000517294.1
ENST00000370809.4
CCDC160
coiled-coil domain containing 160
chr7_+_75932863 0.13 ENST00000429938.1
HSPB1
heat shock 27kDa protein 1
chr22_+_35653445 0.13 ENST00000420166.1
ENST00000444518.2
ENST00000455359.1
ENST00000216106.5
HMGXB4
HMG box domain containing 4
chr12_+_111051832 0.13 ENST00000550703.2
ENST00000551590.1
TCTN1
tectonic family member 1
chr2_+_231191875 0.13 ENST00000444636.1
ENST00000415673.2
ENST00000243810.6
ENST00000396563.4
SP140L
SP140 nuclear body protein-like
chr17_-_60005365 0.13 ENST00000444766.3
INTS2
integrator complex subunit 2
chr8_+_71383312 0.13 ENST00000520259.1
RP11-333A23.4
RP11-333A23.4
chr6_+_36165133 0.13 ENST00000446974.1
ENST00000454960.1
BRPF3
bromodomain and PHD finger containing, 3
chr5_+_133707252 0.13 ENST00000506787.1
ENST00000507277.1
UBE2B
ubiquitin-conjugating enzyme E2B
chr14_-_24898731 0.13 ENST00000267406.6
CBLN3
cerebellin 3 precursor
chr5_+_31532373 0.13 ENST00000325366.9
ENST00000355907.3
ENST00000507818.2
C5orf22
chromosome 5 open reading frame 22
chr16_-_31147020 0.13 ENST00000568261.1
ENST00000567797.1
ENST00000317508.6
PRSS8
protease, serine, 8
chr19_-_44172396 0.13 ENST00000602141.1
ENST00000593939.1
ENST00000599546.1
PLAUR
plasminogen activator, urokinase receptor
chr1_-_150693305 0.13 ENST00000368987.1
HORMAD1
HORMA domain containing 1
chr3_-_57113314 0.13 ENST00000338458.4
ENST00000468727.1
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr17_+_75401152 0.13 ENST00000585930.1
SEPT9
septin 9
chr2_-_148778323 0.13 ENST00000440042.1
ENST00000535373.1
ENST00000540442.1
ENST00000536575.1
ORC4
origin recognition complex, subunit 4
chr3_+_44754126 0.12 ENST00000449836.1
ENST00000436624.2
ENST00000296091.4
ENST00000411443.1
ZNF502
zinc finger protein 502
chr12_-_123011536 0.12 ENST00000331738.7
ENST00000354654.2
RSRC2
arginine/serine-rich coiled-coil 2
chr4_-_141348763 0.12 ENST00000509477.1
CLGN
calmegin
chr4_+_57845024 0.12 ENST00000431623.2
ENST00000441246.2
POLR2B
polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
chr5_+_172483347 0.12 ENST00000522692.1
ENST00000296953.2
ENST00000540014.1
ENST00000520420.1
CREBRF
CREB3 regulatory factor
chr2_+_128377550 0.12 ENST00000437387.1
ENST00000409090.1
MYO7B
myosin VIIB
chr1_+_7844312 0.12 ENST00000377541.1
PER3
period circadian clock 3
chr3_+_44803209 0.12 ENST00000326047.4
KIF15
kinesin family member 15
chr14_-_55658252 0.12 ENST00000395425.2
DLGAP5
discs, large (Drosophila) homolog-associated protein 5
chr3_-_19988462 0.12 ENST00000344838.4
EFHB
EF-hand domain family, member B
chr15_-_77712477 0.12 ENST00000560626.2
PEAK1
pseudopodium-enriched atypical kinase 1
chr3_+_171758344 0.12 ENST00000336824.4
ENST00000423424.1
FNDC3B
fibronectin type III domain containing 3B
chr17_-_56769382 0.12 ENST00000240361.8
ENST00000349033.5
ENST00000389934.3
TEX14
testis expressed 14
chrX_-_119695279 0.12 ENST00000336592.6
CUL4B
cullin 4B
chr17_-_9479128 0.12 ENST00000574431.1
STX8
syntaxin 8
chr14_-_55658323 0.12 ENST00000554067.1
ENST00000247191.2
DLGAP5
discs, large (Drosophila) homolog-associated protein 5
chr17_-_15165854 0.12 ENST00000395936.1
ENST00000395938.2
PMP22
peripheral myelin protein 22
chr8_+_27632083 0.12 ENST00000519637.1
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr1_+_150245177 0.11 ENST00000369098.3
C1orf54
chromosome 1 open reading frame 54
chr18_+_21718924 0.11 ENST00000399496.3
CABYR
calcium binding tyrosine-(Y)-phosphorylation regulated
chr7_+_856246 0.11 ENST00000389574.3
ENST00000457378.2
ENST00000452783.2
ENST00000435699.1
ENST00000440380.1
ENST00000439679.1
ENST00000424128.1
SUN1
Sad1 and UNC84 domain containing 1
chr6_-_84937314 0.11 ENST00000257766.4
ENST00000403245.3
KIAA1009
KIAA1009
chr4_-_113558014 0.11 ENST00000503172.1
ENST00000505019.1
ENST00000309071.5
C4orf21
chromosome 4 open reading frame 21
chr1_+_97187318 0.11 ENST00000609116.1
ENST00000370198.1
ENST00000370197.1
ENST00000426398.2
ENST00000394184.3
PTBP2
polypyrimidine tract binding protein 2
chr12_-_6772249 0.11 ENST00000467678.1
ENST00000493873.1
ENST00000423703.2
ENST00000412586.2
ENST00000444704.2
ING4
inhibitor of growth family, member 4
chr9_+_8858102 0.11 ENST00000447950.1
ENST00000430766.1
RP11-75C9.1
RP11-75C9.1
chr19_+_49977818 0.11 ENST00000594009.1
ENST00000595510.1
FLT3LG
fms-related tyrosine kinase 3 ligand
chr17_-_59940830 0.11 ENST00000259008.2
BRIP1
BRCA1 interacting protein C-terminal helicase 1
chr22_+_38071615 0.11 ENST00000215909.5
LGALS1
lectin, galactoside-binding, soluble, 1
chr10_-_104178857 0.11 ENST00000020673.5
PSD
pleckstrin and Sec7 domain containing
chr15_+_44719394 0.11 ENST00000260327.4
ENST00000396780.1
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr4_-_113558079 0.10 ENST00000445203.2
C4orf21
chromosome 4 open reading frame 21
chr14_+_36295504 0.10 ENST00000216807.7
BRMS1L
breast cancer metastasis-suppressor 1-like
chr5_+_34757309 0.10 ENST00000397449.1
RAI14
retinoic acid induced 14
chr6_-_26659913 0.10 ENST00000480036.1
ENST00000415922.2
ZNF322
zinc finger protein 322
chr10_+_35416090 0.10 ENST00000354759.3
CREM
cAMP responsive element modulator
chr3_-_125313934 0.10 ENST00000296220.5
OSBPL11
oxysterol binding protein-like 11
chr7_+_128379346 0.10 ENST00000535011.2
ENST00000542996.2
ENST00000535623.1
ENST00000538546.1
ENST00000249364.4
ENST00000449187.2
CALU
calumenin
chr13_+_32889605 0.10 ENST00000380152.3
ENST00000544455.1
ENST00000530893.2
BRCA2
breast cancer 2, early onset
chrX_+_24073048 0.10 ENST00000423068.1
EIF2S3
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
chr7_-_21985656 0.10 ENST00000406877.3
CDCA7L
cell division cycle associated 7-like
chr17_+_47075023 0.10 ENST00000431824.2
IGF2BP1
insulin-like growth factor 2 mRNA binding protein 1
chr4_-_84035868 0.10 ENST00000426923.2
ENST00000509973.1
PLAC8
placenta-specific 8
chr8_+_27631903 0.10 ENST00000305188.8
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr3_-_46875313 0.10 ENST00000447340.1
PRSS42
protease, serine, 42
chr5_-_79950371 0.10 ENST00000511032.1
ENST00000504396.1
ENST00000505337.1
DHFR
dihydrofolate reductase
chr14_-_77737543 0.10 ENST00000298352.4
NGB
neuroglobin
chr4_+_57845043 0.10 ENST00000433463.1
ENST00000314595.5
POLR2B
polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
chr11_-_71639446 0.09 ENST00000534704.1
RP11-849H4.2
Putative short transient receptor potential channel 2-like protein
chr10_+_115312825 0.09 ENST00000537906.1
ENST00000541666.1
HABP2
hyaluronan binding protein 2
chr3_-_119396193 0.09 ENST00000484810.1
ENST00000497116.1
ENST00000261070.2
COX17
COX17 cytochrome c oxidase copper chaperone
chr17_-_29151794 0.09 ENST00000324238.6
CRLF3
cytokine receptor-like factor 3
chr7_-_152373216 0.09 ENST00000359321.1
XRCC2
X-ray repair complementing defective repair in Chinese hamster cells 2
chr16_+_84875609 0.09 ENST00000563066.1
CRISPLD2
cysteine-rich secretory protein LCCL domain containing 2
chr2_-_152146385 0.09 ENST00000414946.1
ENST00000243346.5
NMI
N-myc (and STAT) interactor
chr7_-_21985489 0.09 ENST00000356195.5
ENST00000447180.1
ENST00000373934.4
ENST00000457951.1
CDCA7L
cell division cycle associated 7-like
chr6_-_90348440 0.09 ENST00000520441.1
ENST00000520318.1
ENST00000523377.1
LYRM2
LYR motif containing 2
chr3_-_44803141 0.09 ENST00000296121.4
KIAA1143
KIAA1143
chr1_+_46859933 0.09 ENST00000243167.8
FAAH
fatty acid amide hydrolase
chr15_-_57025728 0.09 ENST00000559352.1
ZNF280D
zinc finger protein 280D
chr2_+_230787201 0.09 ENST00000283946.3
FBXO36
F-box protein 36
chr15_-_34635314 0.09 ENST00000557912.1
ENST00000328848.4
NOP10
NOP10 ribonucleoprotein
chr4_+_25378912 0.09 ENST00000510092.1
ENST00000505991.1
ANAPC4
anaphase promoting complex subunit 4

Network of associatons between targets according to the STRING database.

First level regulatory network of E2F8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:1990922 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.1 0.4 GO:0060629 meiotic DNA double-strand break formation(GO:0042138) regulation of homologous chromosome segregation(GO:0060629)
0.1 0.3 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.1 0.3 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.1 0.5 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 0.5 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.1 0.3 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.2 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.1 0.4 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.0 0.1 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.0 0.3 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.5 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.2 GO:0032097 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0 0.1 GO:0000706 meiotic DNA double-strand break processing(GO:0000706) double-strand break repair involved in meiotic recombination(GO:1990918)
0.0 0.4 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.2 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.0 0.2 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.0 0.2 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.1 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.0 0.1 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.0 0.2 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.2 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.1 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885)
0.0 0.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.1 GO:0071677 positive regulation of mononuclear cell migration(GO:0071677) negative regulation of immunological synapse formation(GO:2000521)
0.0 0.1 GO:0016310 phosphorylation(GO:0016310)
0.0 0.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.1 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.0 0.1 GO:0060829 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827) negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.0 0.1 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.0 0.1 GO:0045349 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.0 0.1 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398) positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.2 GO:0019075 virus maturation(GO:0019075)
0.0 0.1 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.2 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.1 GO:1903452 regulation of G1 to G0 transition(GO:1903450) positive regulation of G1 to G0 transition(GO:1903452)
0.0 0.2 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.1 GO:0048003 synaptic vesicle recycling via endosome(GO:0036466) antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.1 GO:0072423 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.0 0.1 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.1 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.1 GO:0002317 plasma cell differentiation(GO:0002317) response to isolation stress(GO:0035900)
0.0 0.3 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.1 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.1 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.1 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 0.1 GO:0085020 protein K6-linked ubiquitination(GO:0085020)
0.0 0.1 GO:0044789 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 0.1 GO:0032466 negative regulation of cytokinesis(GO:0032466)
0.0 0.0 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.0 0.1 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.1 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.0 0.1 GO:1904970 brush border assembly(GO:1904970)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:0072276 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.0 0.3 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.2 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.4 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.0 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.4 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.3 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.1 GO:0090650 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.1 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.1 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 0.1 GO:0061055 myotome development(GO:0061055)
0.0 0.1 GO:0034398 telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.0 GO:0090096 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.0 0.0 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.0 0.0 GO:1904117 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.0 0.1 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0005873 plus-end kinesin complex(GO:0005873)
0.1 0.4 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.2 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.1 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.0 0.3 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.3 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.2 GO:0034448 EGO complex(GO:0034448)
0.0 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.4 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.1 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.0 0.1 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.4 GO:0001741 XY body(GO:0001741)
0.0 0.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.1 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.2 GO:0000243 commitment complex(GO:0000243)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.6 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.1 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.1 GO:0090661 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.4 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.0 GO:1990423 RZZ complex(GO:1990423)
0.0 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.1 0.4 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.1 0.2 GO:0000224 peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity(GO:0000224)
0.1 0.2 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.1 0.3 GO:0003896 DNA primase activity(GO:0003896)
0.1 0.4 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.0 0.1 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.0 0.4 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.4 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.1 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.1 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.1 GO:0051870 methotrexate binding(GO:0051870)
0.0 0.4 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.2 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.2 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.2 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.3 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0017129 triglyceride binding(GO:0017129)
0.0 0.1 GO:0004040 amidase activity(GO:0004040)
0.0 0.1 GO:0005018 platelet-derived growth factor alpha-receptor activity(GO:0005018)
0.0 0.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.1 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.1 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.1 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.5 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.2 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.0 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.0 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.0 0.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.0 GO:0002113 interleukin-33 binding(GO:0002113)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.2 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.2 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1