Project

A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

Navigation
Downloads

Results for E2F7_E2F1

Z-value: 1.05

Motif logo

Transcription factors associated with E2F7_E2F1

Gene Symbol Gene ID Gene Info
ENSG00000165891.11 E2F transcription factor 7
ENSG00000101412.9 E2F transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2F1hg19_v2_chr20_-_32274179_32274213-0.928.2e-02Click!
E2F7hg19_v2_chr12_-_77459306_774593650.524.8e-01Click!

Activity profile of E2F7_E2F1 motif

Sorted Z-values of E2F7_E2F1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_48673465 1.24 ENST00000598938.1
ligase I, DNA, ATP-dependent
chr2_-_219433014 0.59 ENST00000418019.1
ENST00000454775.1
ENST00000338465.5
ENST00000415516.1
ENST00000258399.3
ubiquitin specific peptidase 37
chr16_-_66835480 0.54 ENST00000559050.1
ENST00000558713.2
ENST00000433154.1
ENST00000432602.1
ENST00000433574.1
ENST00000415744.1
coiled-coil domain containing 79
chr15_-_71184724 0.46 ENST00000560604.1
THAP domain containing 10
chr10_+_103912137 0.46 ENST00000603742.1
ENST00000488254.2
ENST00000461421.1
ENST00000476468.1
ENST00000370007.5
nucleolar and coiled-body phosphoprotein 1
chr1_+_60280458 0.40 ENST00000455990.1
ENST00000371208.3
hook microtubule-tethering protein 1
chr1_-_91487770 0.39 ENST00000337393.5
zinc finger protein 644
chrX_-_20159934 0.37 ENST00000379593.1
ENST00000379607.5
eukaryotic translation initiation factor 1A, X-linked
chr2_-_17935027 0.37 ENST00000446852.1
structural maintenance of chromosomes 6
chr22_+_20105012 0.37 ENST00000331821.3
ENST00000411892.1
RAN binding protein 1
chrX_+_17755563 0.37 ENST00000380045.3
ENST00000380041.3
ENST00000380043.3
ENST00000398080.1
sex comb on midleg-like 1 (Drosophila)
chr6_-_18155285 0.37 ENST00000309983.4
thiopurine S-methyltransferase
chr9_-_27573651 0.36 ENST00000379995.1
ENST00000379997.3
chromosome 9 open reading frame 72
chr2_-_203103185 0.36 ENST00000409205.1
small ubiquitin-like modifier 1
chr11_-_93276514 0.36 ENST00000526869.1
single-pass membrane protein with coiled-coil domains 4
chr10_+_14880364 0.35 ENST00000441647.1
heat shock 70kDa protein 14
chr8_-_95907423 0.35 ENST00000396133.3
ENST00000308108.4
cyclin E2
chr1_-_91487806 0.34 ENST00000361321.5
zinc finger protein 644
chr22_+_20105259 0.34 ENST00000416427.1
ENST00000421656.1
ENST00000423859.1
ENST00000418705.2
RAN binding protein 1
chr2_-_110371720 0.34 ENST00000356688.4
septin 10
chr1_-_154155675 0.34 ENST00000330188.9
ENST00000341485.5
tropomyosin 3
chr22_+_20104947 0.34 ENST00000402752.1
RAN binding protein 1
chr2_-_110371412 0.34 ENST00000415095.1
ENST00000334001.6
ENST00000437928.1
ENST00000493445.1
ENST00000397714.2
ENST00000461295.1
septin 10
chr10_-_75634219 0.34 ENST00000305762.7
calcium/calmodulin-dependent protein kinase II gamma
chr11_-_59436453 0.34 ENST00000300146.9
protein associated with topoisomerase II homolog 1 (yeast)
chr22_+_35653445 0.32 ENST00000420166.1
ENST00000444518.2
ENST00000455359.1
ENST00000216106.5
HMG box domain containing 4
chr4_-_39367949 0.32 ENST00000503784.1
ENST00000349703.2
ENST00000381897.1
replication factor C (activator 1) 1, 145kDa
chr1_-_154155595 0.31 ENST00000328159.4
ENST00000368531.2
ENST00000323144.7
ENST00000368533.3
ENST00000341372.3
tropomyosin 3
chr7_-_72936608 0.31 ENST00000404251.1
bromodomain adjacent to zinc finger domain, 1B
chr12_-_48499591 0.31 ENST00000551330.1
ENST00000004980.5
ENST00000339976.6
ENST00000448372.1
SUMO1/sentrin specific peptidase 1
chr14_+_36295638 0.31 ENST00000543183.1
breast cancer metastasis-suppressor 1-like
chrX_+_146993534 0.31 ENST00000334557.6
ENST00000439526.2
ENST00000370475.4
fragile X mental retardation 1
chr1_-_36235529 0.30 ENST00000318121.3
ENST00000373220.3
ENST00000520551.1
claspin
chr11_-_19263145 0.30 ENST00000532666.1
ENST00000527884.1
E2F transcription factor 8
chr4_-_83933999 0.30 ENST00000510557.1
lin-54 homolog (C. elegans)
chrX_+_146993648 0.30 ENST00000370470.1
fragile X mental retardation 1
chr6_-_160210604 0.30 ENST00000420894.2
ENST00000539756.1
ENST00000544255.1
t-complex 1
chr5_+_61602236 0.30 ENST00000514082.1
ENST00000407818.3
kinesin heavy chain member 2A
chr15_+_44719970 0.30 ENST00000558966.1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr2_-_17935059 0.29 ENST00000448223.2
ENST00000381272.4
ENST00000351948.4
structural maintenance of chromosomes 6
chr19_-_48673552 0.29 ENST00000536218.1
ENST00000596549.1
ligase I, DNA, ATP-dependent
chr2_-_110371777 0.29 ENST00000397712.2
septin 10
chr6_-_146056341 0.29 ENST00000435470.1
epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
chr7_-_130080681 0.29 ENST00000469826.1
centrosomal protein 41kDa
chr4_-_174255400 0.28 ENST00000506267.1
high mobility group box 2
chr9_+_17134980 0.28 ENST00000380647.3
centlein, centrosomal protein
chr2_+_238600788 0.28 ENST00000289175.6
ENST00000244815.5
leucine rich repeat (in FLII) interacting protein 1
chr1_-_150693318 0.28 ENST00000442853.1
ENST00000368995.4
ENST00000368993.2
ENST00000361824.2
ENST00000322343.7
HORMA domain containing 1
chr10_-_70166999 0.28 ENST00000454950.2
ENST00000342616.4
ENST00000602465.1
ENST00000399200.2
RUN and FYVE domain containing 2
chr2_+_48010312 0.27 ENST00000540021.1
mutS homolog 6
chr1_-_36235559 0.27 ENST00000251195.5
claspin
chrX_+_53449887 0.27 ENST00000375327.3
RIB43A domain with coiled-coils 1
chr14_-_93673353 0.27 ENST00000556566.1
ENST00000306954.4
chromosome 14 open reading frame 142
chrX_+_17755696 0.26 ENST00000419185.1
sex comb on midleg-like 1 (Drosophila)
chr14_-_45603657 0.26 ENST00000396062.3
FK506 binding protein 3, 25kDa
chr6_-_17706618 0.26 ENST00000262077.2
ENST00000537253.1
nucleoporin 153kDa
chr20_+_57466629 0.26 ENST00000371081.1
ENST00000338783.6
GNAS complex locus
chr1_+_185014647 0.25 ENST00000367509.4
ring finger protein 2
chr11_+_58874658 0.25 ENST00000411426.1
family with sequence similarity 111, member B
chr3_-_113415441 0.25 ENST00000491165.1
ENST00000316407.4
KIAA2018
chr2_+_219433588 0.25 ENST00000295701.5
RCD1 required for cell differentiation1 homolog (S. pombe)
chr2_+_48010221 0.25 ENST00000234420.5
mutS homolog 6
chr17_-_58469687 0.25 ENST00000590133.1
ubiquitin specific peptidase 32
chr2_-_203103281 0.25 ENST00000392244.3
ENST00000409181.1
ENST00000409712.1
ENST00000409498.2
ENST00000409368.1
ENST00000392245.1
ENST00000392246.2
small ubiquitin-like modifier 1
chr11_+_9595180 0.25 ENST00000450114.2
WEE1 G2 checkpoint kinase
chr16_-_75467274 0.25 ENST00000566254.1
craniofacial development protein 1
chr17_-_58469329 0.25 ENST00000393003.3
ubiquitin specific peptidase 32
chr1_-_23670813 0.25 ENST00000374612.1
heterogeneous nuclear ribonucleoprotein R
chr1_+_91966384 0.25 ENST00000430031.2
ENST00000234626.6
cell division cycle 7
chr18_+_34409069 0.25 ENST00000543923.1
ENST00000280020.5
ENST00000435985.2
ENST00000592521.1
ENST00000587139.1
KIAA1328
chr5_+_61601965 0.24 ENST00000401507.3
kinesin heavy chain member 2A
chr6_-_18264706 0.24 ENST00000244776.7
ENST00000503715.1
DEK oncogene
chr3_-_128902729 0.24 ENST00000451728.2
ENST00000446936.2
ENST00000502976.1
ENST00000500450.2
ENST00000441626.2
CCHC-type zinc finger, nucleic acid binding protein
chr17_-_48943706 0.24 ENST00000499247.2
transducer of ERBB2, 1
chr4_-_77069533 0.24 ENST00000514987.1
ENST00000458189.2
ENST00000514901.1
ENST00000342467.6
nucleoporin 54kDa
chr9_+_17135016 0.24 ENST00000425824.1
ENST00000262360.5
ENST00000380641.4
centlein, centrosomal protein
chr1_+_25071848 0.24 ENST00000374379.4
chloride intracellular channel 4
chr1_-_23670752 0.24 ENST00000302271.6
ENST00000426846.2
ENST00000427764.2
ENST00000606561.1
ENST00000374616.3
heterogeneous nuclear ribonucleoprotein R
chr1_-_38455650 0.24 ENST00000448721.2
splicing factor 3a, subunit 3, 60kDa
chrX_-_53449593 0.24 ENST00000375340.6
ENST00000322213.4
structural maintenance of chromosomes 1A
chr10_+_103911926 0.24 ENST00000605788.1
ENST00000405356.1
nucleolar and coiled-body phosphoprotein 1
chr11_-_93276582 0.24 ENST00000298966.2
single-pass membrane protein with coiled-coil domains 4
chr20_-_35724388 0.24 ENST00000344359.3
ENST00000373664.3
retinoblastoma-like 1 (p107)
chr7_+_116593536 0.23 ENST00000417919.1
suppression of tumorigenicity 7
chr7_+_116593568 0.23 ENST00000446490.1
suppression of tumorigenicity 7
chr12_-_57146095 0.23 ENST00000550770.1
ENST00000338193.6
primase, DNA, polypeptide 1 (49kDa)
chr6_-_159065741 0.23 ENST00000367085.3
ENST00000367089.3
dynein, light chain, Tctex-type 1
chr4_-_77069573 0.22 ENST00000264883.3
nucleoporin 54kDa
chr5_+_68485433 0.22 ENST00000502689.1
centromere protein H
chr13_+_49822041 0.22 ENST00000538056.1
ENST00000251108.6
ENST00000444959.1
ENST00000429346.1
cytidine and dCMP deaminase domain containing 1
chr2_-_176033066 0.22 ENST00000437522.1
activating transcription factor 2
chr1_-_23670817 0.22 ENST00000478691.1
heterogeneous nuclear ribonucleoprotein R
chr16_+_19729586 0.22 ENST00000564186.1
ENST00000541926.1
ENST00000433597.2
IQ motif containing K
chr11_+_58874701 0.22 ENST00000529618.1
ENST00000534403.1
ENST00000343597.3
family with sequence similarity 111, member B
chr9_+_128509663 0.22 ENST00000373489.5
ENST00000373483.2
pre-B-cell leukemia homeobox 3
chr1_-_159915386 0.22 ENST00000361509.3
ENST00000368094.1
immunoglobulin superfamily, member 9
chr4_-_83821676 0.21 ENST00000355196.2
ENST00000507676.1
ENST00000506495.1
ENST00000507051.1
SEC31 homolog A (S. cerevisiae)
chr2_+_61293021 0.21 ENST00000402291.1
KIAA1841
chr13_-_44453826 0.21 ENST00000444614.3
coiled-coil domain containing 122
chr1_+_185014496 0.21 ENST00000367510.3
ring finger protein 2
chr8_-_38034234 0.21 ENST00000311351.4
LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr3_+_52719936 0.21 ENST00000418458.1
ENST00000394799.2
guanine nucleotide binding protein-like 3 (nucleolar)
chr6_-_160210715 0.21 ENST00000392168.2
ENST00000321394.7
t-complex 1
chr4_+_40058411 0.21 ENST00000261435.6
ENST00000515550.1
NEDD4 binding protein 2
chr14_+_96968802 0.21 ENST00000556619.1
ENST00000392990.2
poly(A) polymerase alpha
chr17_+_76183398 0.21 ENST00000409257.5
arylformamidase
chr3_+_142720366 0.21 ENST00000493782.1
ENST00000397933.2
ENST00000473835.2
ENST00000493598.2
U2 snRNP-associated SURP domain containing
chr1_+_6845497 0.21 ENST00000473578.1
ENST00000557126.1
calmodulin binding transcription activator 1
chr8_+_141522017 0.21 ENST00000518971.1
ENST00000519618.1
chromatin accessibility complex 1
chr8_-_132052458 0.21 ENST00000377928.3
adenylate cyclase 8 (brain)
chr16_-_69419473 0.21 ENST00000566750.1
telomeric repeat binding factor 2
chr2_+_24346324 0.21 ENST00000407625.1
ENST00000420135.2
family with sequence similarity 228, member B
chr17_+_30264014 0.21 ENST00000322652.5
ENST00000580398.1
SUZ12 polycomb repressive complex 2 subunit
chr20_+_36661910 0.21 ENST00000373433.4
regulation of nuclear pre-mRNA domain containing 1B
chr4_-_18023350 0.21 ENST00000539056.1
ENST00000382226.5
ENST00000326877.4
ligand dependent nuclear receptor corepressor-like
chr4_-_1714037 0.20 ENST00000488267.1
ENST00000429429.2
ENST00000480936.1
stem-loop binding protein
chr2_+_48541776 0.20 ENST00000413569.1
ENST00000340553.3
forkhead box N2
chr9_+_123837141 0.20 ENST00000373865.2
centriolin
chr18_-_54318353 0.20 ENST00000590954.1
ENST00000540155.1
thioredoxin-like 1
chr10_-_75634260 0.20 ENST00000372765.1
ENST00000351293.3
calcium/calmodulin-dependent protein kinase II gamma
chr17_-_59940830 0.20 ENST00000259008.2
BRCA1 interacting protein C-terminal helicase 1
chr10_-_70166946 0.20 ENST00000388768.2
RUN and FYVE domain containing 2
chr6_-_35109080 0.20 ENST00000486638.1
ENST00000505400.1
ENST00000412155.2
ENST00000373979.2
ENST00000507706.1
ENST00000444780.2
ENST00000492680.2
t-complex 11, testis-specific
chr13_+_32889605 0.20 ENST00000380152.3
ENST00000544455.1
ENST00000530893.2
breast cancer 2, early onset
chr11_-_19262486 0.20 ENST00000250024.4
E2F transcription factor 8
chr11_+_17298297 0.20 ENST00000529010.1
nucleobindin 2
chr6_-_74161977 0.19 ENST00000370318.1
ENST00000370315.3
Mab-21 domain containing 1
chr6_+_17281573 0.19 ENST00000379052.5
RNA binding motif protein 24
chr4_+_57302297 0.19 ENST00000399688.3
ENST00000512576.1
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr3_+_62304648 0.19 ENST00000462069.1
ENST00000232519.5
ENST00000465142.1
chromosome 3 open reading frame 14
chr3_+_128997648 0.19 ENST00000509042.1
ENST00000383463.4
ENST00000417226.2
ENST00000510314.1
5-hydroxymethylcytosine (hmC) binding, ES cell-specific
chr9_+_131451480 0.19 ENST00000322030.8
SET nuclear oncogene
chr6_+_31633011 0.19 ENST00000375885.4
casein kinase 2, beta polypeptide
chr5_-_159546396 0.19 ENST00000523662.1
ENST00000456329.3
ENST00000307063.7
PWWP domain containing 2A
chr14_+_20811722 0.19 ENST00000429687.3
poly (ADP-ribose) polymerase 2
chr15_+_82555169 0.19 ENST00000565432.1
ENST00000427381.2
family with sequence similarity 154, member B
chr6_-_108279369 0.19 ENST00000369002.4
SEC63 homolog (S. cerevisiae)
chr14_+_20811766 0.19 ENST00000250416.5
ENST00000527915.1
poly (ADP-ribose) polymerase 2
chr7_-_148581360 0.19 ENST00000320356.2
ENST00000541220.1
ENST00000483967.1
ENST00000536783.1
enhancer of zeste homolog 2 (Drosophila)
chr21_-_19191703 0.19 ENST00000284881.4
ENST00000400559.3
ENST00000400558.3
chromosome 21 open reading frame 91
chr4_-_174254823 0.19 ENST00000438704.2
high mobility group box 2
chr14_-_74892805 0.19 ENST00000331628.3
ENST00000554953.1
synapse differentiation inducing 1-like
chr2_+_179316163 0.19 ENST00000409117.3
deafness, autosomal recessive 59
chr4_-_1107306 0.18 ENST00000433731.2
ENST00000333673.5
ENST00000382968.5
ring finger protein 212
chr2_+_110371905 0.18 ENST00000356454.3
sosondowah ankyrin repeat domain family member C
chrX_+_100646190 0.18 ENST00000471855.1
ribosomal protein L36a
chr2_+_61108771 0.18 ENST00000394479.3
v-rel avian reticuloendotheliosis viral oncogene homolog
chr8_+_121457642 0.18 ENST00000305949.1
Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) binding protein, 104kDa
chr1_+_27719148 0.18 ENST00000374024.3
G protein-coupled receptor 3
chr12_-_77459306 0.18 ENST00000547316.1
ENST00000416496.2
ENST00000550669.1
ENST00000322886.7
E2F transcription factor 7
chr3_-_186524234 0.18 ENST00000418288.1
ENST00000296273.2
replication factor C (activator 1) 4, 37kDa
chr8_-_56986768 0.18 ENST00000523936.1
ribosomal protein S20
chr11_+_76156045 0.18 ENST00000533988.1
ENST00000524490.1
ENST00000334736.3
ENST00000343878.3
ENST00000533972.1
chromosome 11 open reading frame 30
chr12_-_88535747 0.18 ENST00000309041.7
centrosomal protein 290kDa
chr7_+_128379449 0.18 ENST00000479257.1
calumenin
chr17_-_42295870 0.18 ENST00000526094.1
ENST00000529383.1
ENST00000530828.1
upstream binding transcription factor, RNA polymerase I
chr12_+_72233487 0.18 ENST00000482439.2
ENST00000550746.1
ENST00000491063.1
ENST00000319106.8
ENST00000485960.2
ENST00000393309.3
TBC1 domain family, member 15
chr12_-_104531785 0.18 ENST00000551727.1
nuclear transcription factor Y, beta
chr19_+_39926791 0.18 ENST00000594990.1
suppressor of Ty 5 homolog (S. cerevisiae)
chr11_-_65641044 0.18 ENST00000527378.1
EGF containing fibulin-like extracellular matrix protein 2
chr2_-_157186630 0.18 ENST00000406048.2
nuclear receptor subfamily 4, group A, member 2
chr2_+_203130439 0.18 ENST00000264279.5
NOP58 ribonucleoprotein
chr11_-_119234876 0.18 ENST00000525735.1
ubiquitin specific peptidase 2
chr14_+_96968707 0.18 ENST00000216277.8
ENST00000557320.1
ENST00000557471.1
poly(A) polymerase alpha
chr22_-_36925124 0.17 ENST00000457241.1
eukaryotic translation initiation factor 3, subunit D
chr4_-_83934078 0.17 ENST00000505397.1
lin-54 homolog (C. elegans)
chr10_+_180987 0.17 ENST00000381591.1
zinc finger, MYND-type containing 11
chr7_-_158497431 0.17 ENST00000449727.2
ENST00000409339.3
ENST00000409423.1
ENST00000356309.3
non-SMC condensin II complex, subunit G2
chrX_+_72062617 0.17 ENST00000440247.1
DMRT-like family C1B
chr4_-_84256024 0.17 ENST00000311412.5
heparanase
chr1_-_150693305 0.17 ENST00000368987.1
HORMA domain containing 1
chrX_-_128657457 0.17 ENST00000371121.3
ENST00000371123.1
ENST00000371122.4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr17_-_1303462 0.17 ENST00000573026.1
ENST00000575977.1
ENST00000571732.1
ENST00000264335.8
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
chr4_-_170679024 0.17 ENST00000393381.2
chromosome 4 open reading frame 27
chr11_+_74303612 0.17 ENST00000527458.1
ENST00000532497.1
ENST00000530511.1
polymerase (DNA-directed), delta 3, accessory subunit
chr5_-_141257954 0.17 ENST00000456271.1
ENST00000394536.3
ENST00000503492.1
ENST00000287008.3
protocadherin 1
chr12_-_120805872 0.17 ENST00000546985.1
musashi RNA-binding protein 1
chr3_-_148804275 0.17 ENST00000392912.2
ENST00000465259.1
ENST00000310053.5
ENST00000494055.1
helicase-like transcription factor
chr10_+_60936921 0.17 ENST00000373878.3
phytanoyl-CoA 2-hydroxylase interacting protein-like
chr8_-_56987061 0.17 ENST00000009589.3
ENST00000524349.1
ENST00000519606.1
ENST00000519807.1
ENST00000521262.1
ENST00000520627.1
ribosomal protein S20
chr8_+_95908041 0.17 ENST00000396113.1
ENST00000519136.1
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr3_+_62304712 0.17 ENST00000494481.1
chromosome 3 open reading frame 14
chr15_-_85259384 0.17 ENST00000455959.3
SEC11 homolog A (S. cerevisiae)
chr22_+_46546406 0.17 ENST00000440343.1
ENST00000415785.1
peroxisome proliferator-activated receptor alpha
chr6_-_41863098 0.17 ENST00000373006.1
ubiquitin specific peptidase 49
chr6_+_132129151 0.17 ENST00000360971.2
ectonucleotide pyrophosphatase/phosphodiesterase 1
chr5_+_61602055 0.17 ENST00000381103.2
kinesin heavy chain member 2A
chr1_+_225965518 0.17 ENST00000304786.7
ENST00000366839.4
ENST00000366838.1
signal recognition particle 9kDa
chr10_-_75634326 0.17 ENST00000322635.3
ENST00000444854.2
ENST00000423381.1
ENST00000322680.3
ENST00000394762.2
calcium/calmodulin-dependent protein kinase II gamma
chr11_-_57102947 0.17 ENST00000526696.1
structure specific recognition protein 1
chr15_-_59041768 0.17 ENST00000402627.1
ENST00000396140.2
ENST00000559053.1
ENST00000561288.1
ADAM metallopeptidase domain 10
chr7_-_129845313 0.16 ENST00000397622.2
transmembrane protein 209
chr9_+_106856541 0.16 ENST00000286398.7
ENST00000440179.1
ENST00000374793.3
structural maintenance of chromosomes 2
chr17_+_30813576 0.16 ENST00000313401.3
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr3_-_10028366 0.16 ENST00000429759.1
ER membrane protein complex subunit 3
chr1_-_228401338 0.16 ENST00000295012.5
chromosome 1 open reading frame 145
chr7_+_26240776 0.16 ENST00000337620.4
chromobox homolog 3
chr9_+_106856831 0.16 ENST00000303219.8
ENST00000374787.3
structural maintenance of chromosomes 2
chr12_+_97300995 0.16 ENST00000266742.4
ENST00000429527.2
ENST00000554226.1
ENST00000557478.1
ENST00000557092.1
ENST00000411739.2
ENST00000553609.1
neural precursor cell expressed, developmentally down-regulated 1
chr12_-_48398104 0.16 ENST00000337299.6
ENST00000380518.3
collagen, type II, alpha 1

Network of associatons between targets according to the STRING database.

First level regulatory network of E2F7_E2F1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:1903461 Okazaki fragment processing involved in mitotic DNA replication(GO:1903461)
0.2 0.7 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.2 0.7 GO:1901254 modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254)
0.2 0.6 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.2 1.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 0.4 GO:0042138 meiotic DNA double-strand break formation(GO:0042138) regulation of homologous chromosome segregation(GO:0060629)
0.1 0.5 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.1 0.3 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.1 0.3 GO:0000706 meiotic DNA double-strand break processing(GO:0000706) double-strand break repair involved in meiotic recombination(GO:1990918)
0.1 0.5 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.1 0.4 GO:0044053 translocation of peptides or proteins into host(GO:0042000) translocation of peptides or proteins into host cell cytoplasm(GO:0044053) translocation of molecules into host(GO:0044417) translocation of peptides or proteins into other organism involved in symbiotic interaction(GO:0051808) translocation of molecules into other organism involved in symbiotic interaction(GO:0051836)
0.1 0.4 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.1 0.4 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.1 0.2 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.1 0.4 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.1 0.4 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.1 0.3 GO:0007388 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.1 0.3 GO:0032240 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.1 0.2 GO:0051492 regulation of stress fiber assembly(GO:0051492)
0.1 0.5 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 0.2 GO:0070510 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
0.1 0.2 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 1.3 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.1 0.1 GO:0002661 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.1 0.3 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.1 0.3 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
0.1 0.5 GO:0000710 meiotic mismatch repair(GO:0000710)
0.1 0.7 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.1 0.1 GO:1904430 negative regulation of t-circle formation(GO:1904430)
0.1 0.2 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.1 0.6 GO:0098535 de novo centriole assembly(GO:0098535)
0.1 0.2 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.1 0.5 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 0.2 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.1 0.2 GO:0051866 general adaptation syndrome(GO:0051866)
0.1 0.2 GO:0072299 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.1 0.2 GO:0072361 regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361)
0.1 0.2 GO:1902309 regulation of heart rate by hormone(GO:0003064) negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.1 0.2 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.1 GO:1900110 negative regulation of histone H3-K9 dimethylation(GO:1900110)
0.1 0.2 GO:0021722 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.1 0.6 GO:0007000 nucleolus organization(GO:0007000)
0.1 0.4 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1 0.3 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1 0.6 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.4 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.1 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 0.3 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512) L-kynurenine metabolic process(GO:0097052)
0.0 0.2 GO:0072423 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.0 0.6 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.6 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.2 GO:1904978 regulation of endosome organization(GO:1904978)
0.0 0.2 GO:0006311 meiotic gene conversion(GO:0006311)
0.0 0.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.5 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.1 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.0 0.1 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.0 0.0 GO:0044771 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.3 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.0 0.0 GO:0035878 nail development(GO:0035878)
0.0 0.2 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.1 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.0 0.1 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.0 0.2 GO:0090272 negative regulation of fibroblast growth factor production(GO:0090272)
0.0 0.2 GO:0097045 phosphatidylserine exposure on blood platelet(GO:0097045)
0.0 0.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.1 GO:0060032 notochord regression(GO:0060032)
0.0 0.6 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.4 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.2 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.0 0.4 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.2 GO:0019060 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.1 GO:0071030 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.0 0.1 GO:0044691 tooth eruption(GO:0044691)
0.0 0.0 GO:0003133 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134) mesenchymal cell proliferation involved in ureteric bud development(GO:0072138)
0.0 0.1 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0 0.2 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.1 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.0 0.2 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.1 GO:0003186 tricuspid valve morphogenesis(GO:0003186)
0.0 0.1 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.1 GO:0001922 B-1 B cell homeostasis(GO:0001922)
0.0 0.6 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 0.0 GO:0031640 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.0 0.3 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.2 GO:0003165 Purkinje myocyte development(GO:0003165)
0.0 0.1 GO:0051780 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.0 0.2 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.1 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.2 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.2 GO:0035936 testosterone secretion(GO:0035936) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
0.0 0.3 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.2 GO:0043418 homocysteine catabolic process(GO:0043418)
0.0 0.3 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.0 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.3 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.2 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.2 GO:0000019 regulation of mitotic recombination(GO:0000019)
0.0 0.3 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.0 0.1 GO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033)
0.0 0.1 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
0.0 0.3 GO:0061042 vascular wound healing(GO:0061042)
0.0 0.1 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.0 0.1 GO:0033504 floor plate development(GO:0033504)
0.0 0.0 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
0.0 0.1 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.0 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.1 GO:0010983 regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.0 0.3 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.1 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
0.0 0.1 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.1 GO:0002331 pre-B cell allelic exclusion(GO:0002331) telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.0 0.1 GO:0060527 prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.0 0.1 GO:0036269 swimming behavior(GO:0036269)
0.0 0.2 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.0 0.1 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
0.0 0.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.1 GO:1902990 mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.0 0.2 GO:0042148 strand invasion(GO:0042148)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0006298 mismatch repair(GO:0006298)
0.0 0.1 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.0 0.1 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.0 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.2 GO:0030035 microspike assembly(GO:0030035)
0.0 0.1 GO:1904808 regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
0.0 0.1 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.0 0.5 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.2 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.1 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.0 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0 0.1 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.0 0.2 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.0 0.0 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.0 0.8 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.7 GO:0014733 regulation of skeletal muscle adaptation(GO:0014733)
0.0 0.1 GO:0045720 negative regulation of integrin biosynthetic process(GO:0045720)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.2 GO:0021943 formation of radial glial scaffolds(GO:0021943)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.1 GO:0070898 RNA polymerase III transcriptional preinitiation complex assembly(GO:0070898)
0.0 0.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.3 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.2 GO:0021683 cerebellar granular layer morphogenesis(GO:0021683)
0.0 0.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.1 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.0 0.5 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0048749 compound eye development(GO:0048749)
0.0 0.3 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.1 GO:1990637 response to prolactin(GO:1990637)
0.0 0.0 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.2 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.2 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.2 GO:0070189 tryptophan catabolic process to kynurenine(GO:0019441) kynurenine metabolic process(GO:0070189)
0.0 0.1 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 0.2 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.0 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.0 0.2 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:0090095 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.0 0.4 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.1 GO:0097195 pilomotor reflex(GO:0097195)
0.0 1.1 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.0 0.1 GO:0002351 serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) serotonin secretion by platelet(GO:0002554)
0.0 0.1 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.1 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 0.0 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.2 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 0.1 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0 0.1 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.1 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.1 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.3 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.0 GO:0032902 nerve growth factor production(GO:0032902)
0.0 0.2 GO:0044070 regulation of anion transport(GO:0044070)
0.0 0.2 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.0 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.1 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.1 GO:0061055 myotome development(GO:0061055)
0.0 0.1 GO:0071047 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.0 0.1 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.0 GO:0003285 septum secundum development(GO:0003285)
0.0 0.1 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.0 0.0 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.3 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.1 GO:2000510 positive regulation of dendritic cell chemotaxis(GO:2000510)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.1 GO:0008291 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0 0.1 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.0 0.1 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.0 0.1 GO:0030047 actin modification(GO:0030047)
0.0 0.1 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.6 GO:1903432 regulation of TORC1 signaling(GO:1903432)
0.0 0.1 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.1 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.0 GO:2000047 cell-cell adhesion mediated by cadherin(GO:0044331) regulation of cell-cell adhesion mediated by cadherin(GO:2000047) positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.1 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.0 0.1 GO:1904617 regulation of actin filament binding(GO:1904529) negative regulation of actin filament binding(GO:1904530) regulation of actin binding(GO:1904616) negative regulation of actin binding(GO:1904617)
0.0 0.4 GO:0097186 amelogenesis(GO:0097186)
0.0 0.1 GO:0016598 protein arginylation(GO:0016598)
0.0 0.2 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.4 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.1 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.1 GO:0085020 protein K6-linked ubiquitination(GO:0085020)
0.0 0.2 GO:0071599 otic vesicle development(GO:0071599)
0.0 0.1 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.0 0.3 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.3 GO:1904816 positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.0 0.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.0 GO:0080154 regulation of fertilization(GO:0080154)
0.0 0.0 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.0 0.1 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.8 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.1 GO:0035188 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.2 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.1 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.0 0.1 GO:0071910 determination of liver left/right asymmetry(GO:0071910)
0.0 0.0 GO:0032242 regulation of nucleoside transport(GO:0032242)
0.0 0.1 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.0 0.1 GO:0090166 Golgi disassembly(GO:0090166)
0.0 0.0 GO:2001053 regulation of mesenchymal cell apoptotic process(GO:2001053) negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.0 0.2 GO:0042473 outer ear morphogenesis(GO:0042473)
0.0 0.0 GO:0048808 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0 0.4 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.0 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.1 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.1 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.0 0.1 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.1 GO:0015798 myo-inositol transport(GO:0015798)
0.0 0.1 GO:0033123 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.0 0.1 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.2 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.2 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.2 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.1 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.0 GO:0048478 replication fork protection(GO:0048478)
0.0 0.0 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.1 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.2 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.0 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.0 0.1 GO:0030920 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.0 0.0 GO:1904438 positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
0.0 0.2 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.1 GO:0071033 nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
0.0 0.0 GO:0036369 transcription factor catabolic process(GO:0036369)
0.0 0.1 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.0 0.0 GO:1904640 response to methionine(GO:1904640)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.4 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.0 GO:0060423 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) regulation of branching involved in lung morphogenesis(GO:0061046) positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.0 0.1 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:0097398 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.4 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.0 GO:0021503 neural fold bending(GO:0021503)
0.0 0.1 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.0 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.0 0.1 GO:1902856 negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.0 0.0 GO:0061073 ciliary body morphogenesis(GO:0061073) cardiac neural crest cell development involved in outflow tract morphogenesis(GO:0061309)
0.0 0.2 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.0 GO:1903998 regulation of eating behavior(GO:1903998)
0.0 0.3 GO:0033151 V(D)J recombination(GO:0033151)
0.0 0.0 GO:0098972 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.0 0.1 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.1 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.0 0.1 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.0 0.2 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.0 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.1 GO:0009216 purine deoxyribonucleoside triphosphate biosynthetic process(GO:0009216) adenosine biosynthetic process(GO:0046086)
0.0 0.1 GO:0070459 prolactin secretion(GO:0070459)
0.0 0.0 GO:0090224 regulation of mitotic spindle organization(GO:0060236) regulation of spindle organization(GO:0090224)
0.0 0.2 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 0.0 GO:0071166 ribonucleoprotein complex localization(GO:0071166)
0.0 0.2 GO:0071360 cellular response to exogenous dsRNA(GO:0071360)
0.0 0.0 GO:0046100 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.0 0.0 GO:0003094 glomerular filtration(GO:0003094) renal filtration(GO:0097205)
0.0 0.1 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.8 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 0.1 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0 0.2 GO:0007141 male meiosis I(GO:0007141)
0.0 0.1 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.0 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.1 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.0 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.0 GO:0044818 mitotic G2/M transition checkpoint(GO:0044818)
0.0 0.2 GO:0060046 regulation of acrosome reaction(GO:0060046)
0.0 0.1 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.1 GO:1902534 single-organism membrane invagination(GO:1902534)
0.0 0.0 GO:0042660 positive regulation of cell fate specification(GO:0042660)
0.0 0.1 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.0 GO:0060214 endocardium formation(GO:0060214)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.1 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.1 GO:0048318 axial mesoderm development(GO:0048318)
0.0 0.1 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.1 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.1 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.0 GO:0042245 RNA repair(GO:0042245)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.0 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0 0.0 GO:0046041 ITP metabolic process(GO:0046041)
0.0 0.0 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 0.1 GO:0060763 positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) mammary gland fat development(GO:0060611) mammary duct terminal end bud growth(GO:0060763) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) positive regulation of microglial cell migration(GO:1904141)
0.0 0.1 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0 0.1 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0 0.1 GO:1903351 response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351)
0.0 0.1 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.0 GO:0060789 hair follicle placode formation(GO:0060789)
0.0 0.0 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.0 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.0 GO:0032077 positive regulation of deoxyribonuclease activity(GO:0032077) positive regulation of endodeoxyribonuclease activity(GO:0032079)
0.0 0.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.5 GO:0046329 negative regulation of JNK cascade(GO:0046329)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:1902737 dendritic filopodium(GO:1902737)
0.1 0.6 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.1 0.6 GO:0032301 MutSalpha complex(GO:0032301)
0.1 0.1 GO:0005683 U7 snRNP(GO:0005683)
0.1 0.1 GO:0032302 MutSbeta complex(GO:0032302)
0.1 0.3 GO:0008623 CHRAC(GO:0008623)
0.1 0.9 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 0.7 GO:0035061 interchromatin granule(GO:0035061)
0.1 0.3 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.1 0.1 GO:0005713 recombination nodule(GO:0005713)
0.1 0.3 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.1 0.3 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.1 0.2 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
0.1 0.2 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.8 GO:0016589 NURF complex(GO:0016589)
0.1 0.3 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
0.1 0.8 GO:0000796 condensin complex(GO:0000796)
0.1 0.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.6 GO:0001940 male pronucleus(GO:0001940)
0.1 0.4 GO:0070695 FHF complex(GO:0070695)
0.0 0.3 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.6 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.0 GO:0005869 dynactin complex(GO:0005869)
0.0 0.4 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.5 GO:0001739 sex chromatin(GO:0001739)
0.0 0.3 GO:0098536 deuterosome(GO:0098536)
0.0 0.3 GO:0045120 pronucleus(GO:0045120)
0.0 0.1 GO:1990298 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.0 0.7 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.2 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.1 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.0 0.2 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.2 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
0.0 0.2 GO:0000811 GINS complex(GO:0000811)
0.0 0.1 GO:0070685 macropinocytic cup(GO:0070685)
0.0 0.3 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.2 GO:0070939 Dsl1p complex(GO:0070939) RZZ complex(GO:1990423)
0.0 0.2 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.1 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.0 0.1 GO:0005584 collagen type I trimer(GO:0005584)
0.0 0.8 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.3 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.4 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.4 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.4 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.4 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:1990075 periciliary membrane compartment(GO:1990075)
0.0 0.1 GO:0032059 bleb(GO:0032059)
0.0 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.2 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.1 GO:0005960 glycine cleavage complex(GO:0005960)
0.0 0.0 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.1 GO:0071020 post-spliceosomal complex(GO:0071020)
0.0 0.2 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.2 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.2 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.3 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0034677 integrin alpha7-beta1 complex(GO:0034677)
0.0 0.1 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.1 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.5 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.2 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 1.9 GO:0015030 Cajal body(GO:0015030)
0.0 0.4 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.3 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.3 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:0034678 integrin alpha8-beta1 complex(GO:0034678)
0.0 0.7 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.3 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.6 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.3 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.1 GO:0002081 outer acrosomal membrane(GO:0002081)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.2 GO:0000800 lateral element(GO:0000800)
0.0 0.4 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.3 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.1 GO:0034753 nuclear aryl hydrocarbon receptor complex(GO:0034753)
0.0 0.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.1 GO:0044609 DBIRD complex(GO:0044609)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.0 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.1 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.1 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.3 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)
0.0 0.1 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.0 GO:1902636 kinociliary basal body(GO:1902636)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.0 GO:0031261 DNA replication preinitiation complex(GO:0031261)
0.0 0.1 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.3 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.2 GO:0097386 glial cell projection(GO:0097386)
0.0 0.0 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.0 0.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.1 GO:0030663 COPI vesicle coat(GO:0030126) COPI-coated vesicle membrane(GO:0030663)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0032044 DSIF complex(GO:0032044)
0.0 0.1 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.1 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.5 GO:0000421 autophagosome membrane(GO:0000421)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.0 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.1 1.0 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.6 GO:0032143 single thymine insertion binding(GO:0032143)
0.1 0.1 GO:0032142 single guanine insertion binding(GO:0032142)
0.1 0.5 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.1 0.3 GO:0047536 2-aminoadipate transaminase activity(GO:0047536)
0.1 0.4 GO:0098808 mRNA cap binding(GO:0098808)
0.1 0.3 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.1 0.3 GO:0051870 methotrexate binding(GO:0051870)
0.1 0.3 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.1 0.3 GO:0036033 mediator complex binding(GO:0036033)
0.1 0.6 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 0.5 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.1 0.7 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 0.6 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.1 0.1 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.1 0.7 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 0.2 GO:0004772 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.1 0.2 GO:0051733 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 0.2 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.1 0.2 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.1 0.4 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.1 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0 0.2 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.2 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.2 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.4 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0031862 prostanoid receptor binding(GO:0031862)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.3 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.7 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0 0.1 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.0 0.2 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 0.4 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.2 GO:0001034 RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.0 0.3 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.1 GO:0005365 myo-inositol transmembrane transporter activity(GO:0005365)
0.0 0.1 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.0 0.3 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.3 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.1 GO:0070336 flap-structured DNA binding(GO:0070336)
0.0 0.1 GO:0004803 transposase activity(GO:0004803)
0.0 0.4 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.7 GO:0043047 single-stranded telomeric DNA binding(GO:0043047)
0.0 0.2 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.1 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.0 0.1 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.2 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.2 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.0 1.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.4 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.2 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 0.1 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.2 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.2 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.5 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.0 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
0.0 0.1 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237) extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.0 0.1 GO:0031493 nucleosomal histone binding(GO:0031493)
0.0 0.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.1 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.0 0.1 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.0 0.3 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.1 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.0 0.2 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.2 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.2 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.2 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 0.2 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.3 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.8 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.0 0.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.1 GO:0070991 medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.0 0.1 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.0 0.0 GO:0000404 heteroduplex DNA loop binding(GO:0000404)
0.0 0.2 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.1 GO:0004057 arginyltransferase activity(GO:0004057)
0.0 0.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.1 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.2 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.0 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.0 0.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.0 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
0.0 0.0 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 0.0 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.0 GO:0048244 phytanoyl-CoA dioxygenase activity(GO:0048244)
0.0 0.0 GO:0016624 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591) oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.0 0.5 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:1990175 EH domain binding(GO:1990175)
0.0 0.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.2 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.1 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.1 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.0 0.1 GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.0 0.2 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.0 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.2 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.1 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.0 0.0 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 0.3 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.0 GO:0015068 amidinotransferase activity(GO:0015067) glycine amidinotransferase activity(GO:0015068)
0.0 0.1 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.4 GO:0034061 DNA polymerase activity(GO:0034061)
0.0 0.1 GO:0052828 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.6 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.6 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.2 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.2 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.1 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.5 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.1 GO:0052832 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.1 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.0 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.4 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.0 GO:0016005 phospholipase A2 activator activity(GO:0016005)
0.0 0.0 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.0 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.2 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.1 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.1 GO:0098988 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) group II metabotropic glutamate receptor activity(GO:0001641) G-protein coupled glutamate receptor activity(GO:0098988)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.0 GO:0035197 siRNA binding(GO:0035197)
0.0 0.1 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.0 GO:0004040 amidase activity(GO:0004040)
0.0 0.0 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.3 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.2 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.0 0.1 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.2 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.0 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.3 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.1 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.0 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.2 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.6 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.4 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.4 PID ATR PATHWAY ATR signaling pathway
0.0 3.0 PID E2F PATHWAY E2F transcription factor network
0.0 0.6 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.9 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.7 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.1 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.2 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.2 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.9 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.6 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.3 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.7 PID AURORA B PATHWAY Aurora B signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.1 2.4 REACTOME LAGGING STRAND SYNTHESIS Genes involved in Lagging Strand Synthesis
0.1 2.0 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.1 REACTOME RNA POL I TRANSCRIPTION Genes involved in RNA Polymerase I Transcription
0.0 0.4 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.5 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.5 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.6 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.4 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 1.1 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.5 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.1 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 0.2 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.7 REACTOME KINESINS Genes involved in Kinesins
0.0 0.7 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.1 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.4 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.4 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.4 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.1 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.3 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.2 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis