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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for E2F4

Z-value: 1.45

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Transcription factors associated with E2F4

Gene Symbol Gene ID Gene Info
ENSG00000205250.4 E2F transcription factor 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2F4hg19_v2_chr16_+_67226019_67226127-0.928.0e-02Click!

Activity profile of E2F4 motif

Sorted Z-values of E2F4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_48673465 0.86 ENST00000598938.1
ligase I, DNA, ATP-dependent
chr2_+_71357434 0.84 ENST00000244230.2
M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
chr15_-_71184724 0.77 ENST00000560604.1
THAP domain containing 10
chr2_+_29033682 0.71 ENST00000379579.4
ENST00000334056.5
ENST00000449210.1
speedy/RINGO cell cycle regulator family member A
chr2_+_71357744 0.60 ENST00000498451.2
M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
chr3_+_180630444 0.59 ENST00000491062.1
ENST00000468861.1
ENST00000445140.2
ENST00000484958.1
fragile X mental retardation, autosomal homolog 1
chr5_-_43313574 0.56 ENST00000325110.6
ENST00000433297.2
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr9_-_113018746 0.54 ENST00000374515.5
thioredoxin
chr2_-_11484710 0.48 ENST00000315872.6
Rho-associated, coiled-coil containing protein kinase 2
chr1_+_185014647 0.47 ENST00000367509.4
ring finger protein 2
chr5_-_43313269 0.46 ENST00000511774.1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr10_+_180987 0.46 ENST00000381591.1
zinc finger, MYND-type containing 11
chr1_-_38455650 0.44 ENST00000448721.2
splicing factor 3a, subunit 3, 60kDa
chr2_+_48010312 0.44 ENST00000540021.1
mutS homolog 6
chr6_+_27833034 0.43 ENST00000357320.2
histone cluster 1, H2al
chr3_-_113415441 0.43 ENST00000491165.1
ENST00000316407.4
KIAA2018
chr15_-_50647274 0.43 ENST00000543881.1
GA binding protein transcription factor, beta subunit 1
chrX_+_14891522 0.42 ENST00000380492.3
ENST00000482354.1
motile sperm domain containing 2
chr4_-_185655212 0.42 ENST00000541971.1
centromere protein U
chr4_-_1714037 0.42 ENST00000488267.1
ENST00000429429.2
ENST00000480936.1
stem-loop binding protein
chr14_-_93673353 0.41 ENST00000556566.1
ENST00000306954.4
chromosome 14 open reading frame 142
chr1_+_185014496 0.41 ENST00000367510.3
ring finger protein 2
chr11_+_45944190 0.41 ENST00000401752.1
ENST00000389968.3
ENST00000325468.5
ENST00000536139.1
glycosyltransferase-like 1B
chr7_-_102985035 0.40 ENST00000426036.2
ENST00000249270.7
ENST00000454277.1
ENST00000412522.1
DnaJ (Hsp40) homolog, subfamily C, member 2
chr15_+_91260552 0.39 ENST00000355112.3
ENST00000560509.1
Bloom syndrome, RecQ helicase-like
chr2_-_203103185 0.39 ENST00000409205.1
small ubiquitin-like modifier 1
chr11_-_61734599 0.39 ENST00000532601.1
ferritin, heavy polypeptide 1
chr4_-_185655278 0.39 ENST00000281453.5
centromere protein U
chr6_-_139695757 0.39 ENST00000367651.2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr9_-_115480303 0.39 ENST00000374234.1
ENST00000374238.1
ENST00000374236.1
ENST00000374242.4
INTS3 and NABP interacting protein
chr4_+_166128836 0.38 ENST00000511305.1
kelch-like family member 2
chr20_-_61493115 0.38 ENST00000335351.3
ENST00000217162.5
transcription factor-like 5 (basic helix-loop-helix)
chr8_-_17104099 0.38 ENST00000524358.1
CCR4-NOT transcription complex, subunit 7
chr16_-_75467274 0.37 ENST00000566254.1
craniofacial development protein 1
chr19_+_7953417 0.37 ENST00000600345.1
ENST00000598224.1
leucine rich repeat containing 8 family, member E
chr19_+_55795493 0.36 ENST00000309383.1
BR serine/threonine kinase 1
chr2_+_173292390 0.36 ENST00000442250.1
ENST00000458358.1
ENST00000409080.1
integrin, alpha 6
chr4_-_1713977 0.35 ENST00000318386.4
stem-loop binding protein
chr2_+_48010221 0.35 ENST00000234420.5
mutS homolog 6
chrX_-_47863348 0.34 ENST00000376943.3
ENST00000396965.1
ENST00000305127.6
zinc finger protein 182
chr15_+_36871983 0.34 ENST00000437989.2
ENST00000569302.1
chromosome 15 open reading frame 41
chr7_-_139876734 0.34 ENST00000006967.5
lysine (K)-specific demethylase 7A
chr19_+_17392672 0.34 ENST00000594072.1
ENST00000598347.1
ankyrin repeat and LEM domain containing 1
chr8_-_95907423 0.34 ENST00000396133.3
ENST00000308108.4
cyclin E2
chr3_-_10028366 0.34 ENST00000429759.1
ER membrane protein complex subunit 3
chr1_+_60280458 0.34 ENST00000455990.1
ENST00000371208.3
hook microtubule-tethering protein 1
chr1_+_65210772 0.34 ENST00000371072.4
ENST00000294428.3
ribonucleoprotein, PTB-binding 2
chr7_-_27135591 0.33 ENST00000343060.4
ENST00000355633.5
homeobox A1
chr6_-_17706618 0.33 ENST00000262077.2
ENST00000537253.1
nucleoporin 153kDa
chr2_-_71357344 0.33 ENST00000494660.2
ENST00000244217.5
ENST00000486135.1
methylmalonyl CoA epimerase
chr8_-_67525473 0.32 ENST00000522677.3
v-myb avian myeloblastosis viral oncogene homolog-like 1
chr4_-_157892055 0.32 ENST00000422544.2
platelet derived growth factor C
chr16_-_66835480 0.32 ENST00000559050.1
ENST00000558713.2
ENST00000433154.1
ENST00000432602.1
ENST00000433574.1
ENST00000415744.1
coiled-coil domain containing 79
chr4_-_39367949 0.32 ENST00000503784.1
ENST00000349703.2
ENST00000381897.1
replication factor C (activator 1) 1, 145kDa
chr2_-_110371720 0.32 ENST00000356688.4
septin 10
chr3_-_112738565 0.32 ENST00000383675.2
ENST00000314400.5
chromosome 3 open reading frame 17
chr2_-_17935027 0.32 ENST00000446852.1
structural maintenance of chromosomes 6
chr9_-_27573651 0.31 ENST00000379995.1
ENST00000379997.3
chromosome 9 open reading frame 72
chr5_-_79950371 0.31 ENST00000511032.1
ENST00000504396.1
ENST00000505337.1
dihydrofolate reductase
chr3_-_49449350 0.31 ENST00000454011.2
ENST00000445425.1
ENST00000422781.1
ras homolog family member A
chrX_-_20159934 0.31 ENST00000379593.1
ENST00000379607.5
eukaryotic translation initiation factor 1A, X-linked
chr15_-_50647347 0.31 ENST00000220429.8
ENST00000429662.2
GA binding protein transcription factor, beta subunit 1
chr1_+_6845497 0.31 ENST00000473578.1
ENST00000557126.1
calmodulin binding transcription activator 1
chr9_+_17134980 0.31 ENST00000380647.3
centlein, centrosomal protein
chr1_-_154531095 0.30 ENST00000292211.4
ubiquitin-conjugating enzyme E2Q family member 1
chr6_-_137113604 0.30 ENST00000359015.4
mitogen-activated protein kinase kinase kinase 5
chr2_-_110371412 0.30 ENST00000415095.1
ENST00000334001.6
ENST00000437928.1
ENST00000493445.1
ENST00000397714.2
ENST00000461295.1
septin 10
chr4_-_157892498 0.30 ENST00000502773.1
platelet derived growth factor C
chrX_+_146993648 0.30 ENST00000370470.1
fragile X mental retardation 1
chr6_-_160210604 0.30 ENST00000420894.2
ENST00000539756.1
ENST00000544255.1
t-complex 1
chr10_-_70166999 0.30 ENST00000454950.2
ENST00000342616.4
ENST00000602465.1
ENST00000399200.2
RUN and FYVE domain containing 2
chr2_+_172778952 0.30 ENST00000392584.1
ENST00000264108.4
histone acetyltransferase 1
chr1_+_6845578 0.30 ENST00000467404.2
ENST00000439411.2
calmodulin binding transcription activator 1
chr7_-_102985288 0.30 ENST00000379263.3
DnaJ (Hsp40) homolog, subfamily C, member 2
chr1_+_27719148 0.30 ENST00000374024.3
G protein-coupled receptor 3
chr6_+_43739697 0.29 ENST00000230480.6
vascular endothelial growth factor A
chr19_-_12912657 0.29 ENST00000301522.2
peroxiredoxin 2
chr9_+_17135016 0.29 ENST00000425824.1
ENST00000262360.5
ENST00000380641.4
centlein, centrosomal protein
chrX_-_130037162 0.29 ENST00000432489.1
ecto-NOX disulfide-thiol exchanger 2
chr10_+_92631709 0.29 ENST00000413330.1
ENST00000277882.3
ribonuclease P/MRP 30kDa subunit
chr3_-_112738490 0.29 ENST00000393857.2
chromosome 3 open reading frame 17
chr10_-_70166946 0.29 ENST00000388768.2
RUN and FYVE domain containing 2
chr13_+_32889605 0.29 ENST00000380152.3
ENST00000544455.1
ENST00000530893.2
breast cancer 2, early onset
chr11_+_36616355 0.29 ENST00000532470.2
chromosome 11 open reading frame 74
chr22_+_20105012 0.28 ENST00000331821.3
ENST00000411892.1
RAN binding protein 1
chr2_-_110371777 0.28 ENST00000397712.2
septin 10
chr20_+_47662805 0.28 ENST00000262982.2
ENST00000542325.1
CSE1 chromosome segregation 1-like (yeast)
chr17_-_73781567 0.27 ENST00000586607.1
H3 histone, family 3B (H3.3B)
chr15_+_42841008 0.27 ENST00000260372.3
ENST00000568876.1
ENST00000568846.2
ENST00000562398.1
HAUS augmin-like complex, subunit 2
chr12_-_48499591 0.27 ENST00000551330.1
ENST00000004980.5
ENST00000339976.6
ENST00000448372.1
SUMO1/sentrin specific peptidase 1
chr11_+_17298522 0.27 ENST00000529313.1
nucleobindin 2
chr1_+_91966384 0.27 ENST00000430031.2
ENST00000234626.6
cell division cycle 7
chr6_-_19804973 0.27 ENST00000457670.1
ENST00000607810.1
ENST00000606628.1
RP4-625H18.2
chr11_-_93276514 0.26 ENST00000526869.1
single-pass membrane protein with coiled-coil domains 4
chr4_-_1107306 0.26 ENST00000433731.2
ENST00000333673.5
ENST00000382968.5
ring finger protein 212
chr14_-_55658323 0.26 ENST00000554067.1
ENST00000247191.2
discs, large (Drosophila) homolog-associated protein 5
chr8_-_103668114 0.26 ENST00000285407.6
Kruppel-like factor 10
chr8_-_29120604 0.26 ENST00000521515.1
kinesin family member 13B
chr6_-_82957433 0.26 ENST00000306270.7
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr2_-_46844242 0.26 ENST00000281382.6
phosphatidylinositol glycan anchor biosynthesis, class F
chrX_+_53449887 0.26 ENST00000375327.3
RIB43A domain with coiled-coils 1
chrX_-_130037198 0.25 ENST00000370935.1
ENST00000338144.3
ENST00000394363.1
ecto-NOX disulfide-thiol exchanger 2
chr11_+_17298543 0.25 ENST00000533926.1
nucleobindin 2
chr3_+_160117418 0.25 ENST00000465903.1
ENST00000485645.1
ENST00000360111.2
ENST00000472991.1
ENST00000467468.1
ENST00000469762.1
ENST00000489573.1
ENST00000462787.1
ENST00000490207.1
ENST00000485867.1
structural maintenance of chromosomes 4
chr22_+_24951949 0.25 ENST00000402849.1
small nuclear ribonucleoprotein D3 polypeptide 18kDa
chr2_-_17935059 0.25 ENST00000448223.2
ENST00000381272.4
ENST00000351948.4
structural maintenance of chromosomes 6
chr19_-_8070474 0.25 ENST00000407627.2
ENST00000593807.1
ELAV like RNA binding protein 1
chr19_+_13049413 0.25 ENST00000316448.5
ENST00000588454.1
calreticulin
chr3_-_148804275 0.24 ENST00000392912.2
ENST00000465259.1
ENST00000310053.5
ENST00000494055.1
helicase-like transcription factor
chr4_+_178230985 0.24 ENST00000264596.3
nei endonuclease VIII-like 3 (E. coli)
chr19_-_49944806 0.24 ENST00000221485.3
solute carrier family 17 (vesicular glutamate transporter), member 7
chr6_-_100016527 0.24 ENST00000523985.1
ENST00000518714.1
ENST00000520371.1
cyclin C
chr21_-_34915084 0.24 ENST00000426819.1
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
chr4_-_120549163 0.24 ENST00000394439.1
ENST00000420633.1
phosphodiesterase 5A, cGMP-specific
chr1_-_36235529 0.24 ENST00000318121.3
ENST00000373220.3
ENST00000520551.1
claspin
chr11_+_17298297 0.23 ENST00000529010.1
nucleobindin 2
chr19_+_34919257 0.23 ENST00000246548.4
ENST00000590048.2
ubiquitin-like modifier activating enzyme 2
chr10_-_35104185 0.23 ENST00000374789.3
ENST00000374788.3
ENST00000346874.4
ENST00000374794.3
ENST00000350537.4
ENST00000374790.3
ENST00000374776.1
ENST00000374773.1
ENST00000545693.1
ENST00000545260.1
ENST00000340077.5
par-3 family cell polarity regulator
chr1_+_104068312 0.23 ENST00000524631.1
ENST00000531883.1
ENST00000533099.1
ENST00000527062.1
RNA-binding region (RNP1, RRM) containing 3
chr10_+_103911926 0.23 ENST00000605788.1
ENST00000405356.1
nucleolar and coiled-body phosphoprotein 1
chr1_+_104068562 0.23 ENST00000423855.2
RNA-binding region (RNP1, RRM) containing 3
chr16_-_49315731 0.23 ENST00000219197.6
cerebellin 1 precursor
chr8_-_17104356 0.23 ENST00000361272.4
ENST00000523917.1
CCR4-NOT transcription complex, subunit 7
chr3_+_52719936 0.23 ENST00000418458.1
ENST00000394799.2
guanine nucleotide binding protein-like 3 (nucleolar)
chr14_+_53019993 0.23 ENST00000542169.2
ENST00000555622.1
G protein-coupled receptor 137C
chr10_-_88281494 0.23 ENST00000298767.5
wings apart-like homolog (Drosophila)
chr11_+_34073195 0.23 ENST00000341394.4
cell cycle associated protein 1
chr12_-_57146095 0.23 ENST00000550770.1
ENST00000338193.6
primase, DNA, polypeptide 1 (49kDa)
chr6_-_139308777 0.23 ENST00000529597.1
ENST00000415951.2
ENST00000367663.4
ENST00000409812.2
RALBP1 associated Eps domain containing 1
chr7_-_129845313 0.23 ENST00000397622.2
transmembrane protein 209
chr15_+_71184931 0.23 ENST00000560369.1
ENST00000260382.5
leucine rich repeat containing 49
chr6_+_151561506 0.23 ENST00000253332.1
A kinase (PRKA) anchor protein 12
chr6_-_160210715 0.23 ENST00000392168.2
ENST00000321394.7
t-complex 1
chr6_+_31633011 0.23 ENST00000375885.4
casein kinase 2, beta polypeptide
chr2_+_48541776 0.22 ENST00000413569.1
ENST00000340553.3
forkhead box N2
chr15_+_36871806 0.22 ENST00000566621.1
ENST00000564586.1
chromosome 15 open reading frame 41
chr4_-_18023350 0.22 ENST00000539056.1
ENST00000382226.5
ENST00000326877.4
ligand dependent nuclear receptor corepressor-like
chr18_-_54318353 0.22 ENST00000590954.1
ENST00000540155.1
thioredoxin-like 1
chr1_+_63833261 0.22 ENST00000371108.4
ALG6, alpha-1,3-glucosyltransferase
chr19_+_39687596 0.22 ENST00000339852.4
non-specific cytotoxic cell receptor protein 1 homolog (zebrafish)
chr12_-_77459306 0.22 ENST00000547316.1
ENST00000416496.2
ENST00000550669.1
ENST00000322886.7
E2F transcription factor 7
chr10_-_70231639 0.22 ENST00000551118.2
ENST00000358410.3
ENST00000399180.2
ENST00000399179.2
DNA replication helicase/nuclease 2
chr8_-_17103951 0.22 ENST00000520178.1
CCR4-NOT transcription complex, subunit 7
chr15_+_71185148 0.22 ENST00000443425.2
ENST00000560755.1
leucine rich repeat containing 49
chr9_-_113018835 0.22 ENST00000374517.5
thioredoxin
chr10_-_30024716 0.22 ENST00000375398.2
ENST00000375400.3
supervillin
chr6_+_135502501 0.22 ENST00000527615.1
ENST00000420123.2
ENST00000525369.1
ENST00000528774.1
ENST00000534121.1
ENST00000534044.1
ENST00000533624.1
v-myb avian myeloblastosis viral oncogene homolog
chr2_-_203736334 0.22 ENST00000392237.2
ENST00000416760.1
ENST00000412210.1
islet cell autoantigen 1,69kDa-like
chrX_-_153363125 0.22 ENST00000407218.1
ENST00000453960.2
methyl CpG binding protein 2 (Rett syndrome)
chr10_-_118764862 0.22 ENST00000260777.10
KIAA1598
chr17_+_76183398 0.21 ENST00000409257.5
arylformamidase
chr1_+_10490441 0.21 ENST00000470413.2
ENST00000309048.3
APITD1-CORT readthrough
apoptosis-inducing, TAF9-like domain 1
chr15_-_42840961 0.21 ENST00000563454.1
ENST00000397130.3
ENST00000570160.1
ENST00000323443.2
leucine rich repeat containing 57
chr8_+_17104539 0.21 ENST00000521829.1
ENST00000521005.1
vacuolar protein sorting 37 homolog A (S. cerevisiae)
chr17_-_38804061 0.21 ENST00000474246.1
ENST00000377808.4
ENST00000578044.1
ENST00000580419.1
ENST00000400122.3
ENST00000580654.1
ENST00000577721.1
ENST00000478349.2
ENST00000431889.2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
chr8_+_95732095 0.21 ENST00000414645.2
dpy-19-like 4 (C. elegans)
chr17_+_34890807 0.21 ENST00000429467.2
ENST00000592983.1
phosphatidylinositol glycan anchor biosynthesis, class W
chr4_+_56815102 0.21 ENST00000257287.4
centrosomal protein 135kDa
chr6_-_100016678 0.21 ENST00000523799.1
ENST00000520429.1
cyclin C
chr6_-_27114577 0.21 ENST00000356950.1
ENST00000396891.4
histone cluster 1, H2bk
chr2_+_61108771 0.21 ENST00000394479.3
v-rel avian reticuloendotheliosis viral oncogene homolog
chr1_-_229761717 0.21 ENST00000366675.3
ENST00000258281.2
ENST00000366674.1
TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
chr19_+_17392467 0.21 ENST00000404085.1
ankyrin repeat and LEM domain containing 1
chr1_-_36235559 0.21 ENST00000251195.5
claspin
chr3_+_180630090 0.21 ENST00000357559.4
ENST00000305586.7
fragile X mental retardation, autosomal homolog 1
chr5_-_36152031 0.20 ENST00000296603.4
LMBR1 domain containing 2
chr6_+_167412835 0.20 ENST00000349556.4
FGFR1 oncogene partner
chr15_+_51973550 0.20 ENST00000220478.3
secretogranin III
chr20_-_35724388 0.20 ENST00000344359.3
ENST00000373664.3
retinoblastoma-like 1 (p107)
chr7_-_152373216 0.20 ENST00000359321.1
X-ray repair complementing defective repair in Chinese hamster cells 2
chr11_+_34073269 0.20 ENST00000389645.3
cell cycle associated protein 1
chr7_+_77166592 0.20 ENST00000248594.6
protein tyrosine phosphatase, non-receptor type 12
chr4_-_83821676 0.20 ENST00000355196.2
ENST00000507676.1
ENST00000506495.1
ENST00000507051.1
SEC31 homolog A (S. cerevisiae)
chr7_+_138145145 0.20 ENST00000415680.2
tripartite motif containing 24
chr8_-_132052458 0.19 ENST00000377928.3
adenylate cyclase 8 (brain)
chr8_+_124084899 0.19 ENST00000287380.1
ENST00000309336.3
ENST00000519418.1
ENST00000327098.5
ENST00000522420.1
ENST00000521676.1
ENST00000378080.2
TBC1 domain family, member 31
chr19_-_48673552 0.19 ENST00000536218.1
ENST00000596549.1
ligase I, DNA, ATP-dependent
chr1_+_33116743 0.19 ENST00000414241.3
ENST00000373493.5
retinoblastoma binding protein 4
chr6_+_71123107 0.19 ENST00000370479.3
ENST00000505769.1
ENST00000515323.1
ENST00000515280.1
ENST00000507085.1
ENST00000457062.2
ENST00000361499.3
family with sequence similarity 135, member A
chr19_-_6424783 0.19 ENST00000398148.3
KH-type splicing regulatory protein
chrX_+_21392529 0.19 ENST00000425654.2
ENST00000543067.1
connector enhancer of kinase suppressor of Ras 2
chr3_-_160117301 0.19 ENST00000326448.7
ENST00000498409.1
ENST00000475677.1
ENST00000478536.1
intraflagellar transport 80 homolog (Chlamydomonas)
chr11_-_123525289 0.19 ENST00000392770.2
ENST00000299333.3
ENST00000530277.1
sodium channel, voltage-gated, type III, beta subunit
chr5_+_148521381 0.19 ENST00000504238.1
actin binding LIM protein family, member 3
chr8_-_38325219 0.19 ENST00000533668.1
ENST00000413133.2
ENST00000397108.4
ENST00000526742.1
ENST00000525001.1
ENST00000425967.3
ENST00000529552.1
ENST00000397113.2
fibroblast growth factor receptor 1
chr5_+_138629389 0.19 ENST00000504045.1
ENST00000504311.1
ENST00000502499.1
matrin 3
chr4_+_331619 0.19 ENST00000505939.1
ENST00000240499.7
zinc finger protein 141
chr3_+_14989186 0.19 ENST00000435454.1
ENST00000323373.6
nuclear receptor subfamily 2, group C, member 2
chr8_+_95908041 0.19 ENST00000396113.1
ENST00000519136.1
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr14_-_71067360 0.19 ENST00000554963.1
ENST00000430055.2
ENST00000440435.2
ENST00000256379.5
mediator complex subunit 6
chr5_+_148521454 0.19 ENST00000508983.1
actin binding LIM protein family, member 3
chr1_-_226496898 0.19 ENST00000481685.1
lin-9 homolog (C. elegans)
chr17_+_44668035 0.19 ENST00000398238.4
ENST00000225282.8
N-ethylmaleimide-sensitive factor
chr8_-_67525524 0.19 ENST00000517885.1
v-myb avian myeloblastosis viral oncogene homolog-like 1
chr16_+_50776021 0.19 ENST00000566679.2
ENST00000564634.1
ENST00000398568.2
cylindromatosis (turban tumor syndrome)
chr6_-_41863098 0.18 ENST00000373006.1
ubiquitin specific peptidase 49
chr3_-_33759541 0.18 ENST00000468888.2
cytoplasmic linker associated protein 2
chr4_+_155665123 0.18 ENST00000336356.3
lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
chr14_-_61190754 0.18 ENST00000216513.4
SIX homeobox 4
chr11_-_119234876 0.18 ENST00000525735.1
ubiquitin specific peptidase 2

Network of associatons between targets according to the STRING database.

First level regulatory network of E2F4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:1903461 Okazaki fragment processing involved in mitotic DNA replication(GO:1903461)
0.1 0.9 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 0.7 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.1 0.4 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.1 0.4 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.1 0.3 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.1 0.3 GO:1990108 protein linear deubiquitination(GO:1990108)
0.1 0.3 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254)
0.1 0.3 GO:1903572 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1 0.3 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.1 0.7 GO:0000710 meiotic mismatch repair(GO:0000710)
0.1 0.6 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.1 0.3 GO:0070510 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
0.1 0.3 GO:0042000 translocation of peptides or proteins into host(GO:0042000) translocation of peptides or proteins into host cell cytoplasm(GO:0044053) translocation of molecules into host(GO:0044417) translocation of peptides or proteins into other organism involved in symbiotic interaction(GO:0051808) translocation of molecules into other organism involved in symbiotic interaction(GO:0051836)
0.1 0.3 GO:1904978 regulation of endosome organization(GO:1904978)
0.1 0.8 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.1 0.2 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.1 0.3 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.1 0.3 GO:0021861 forebrain radial glial cell differentiation(GO:0021861)
0.1 0.4 GO:0035801 adrenal cortex development(GO:0035801) adrenal cortex formation(GO:0035802)
0.1 0.8 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 0.4 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 0.2 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.1 0.2 GO:0009405 pathogenesis(GO:0009405)
0.1 0.8 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.1 0.7 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) negative regulation of mitotic recombination(GO:0045950) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 0.2 GO:0007037 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.1 0.2 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.1 0.2 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.1 1.0 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.1 0.2 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
0.1 0.6 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.1 0.2 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.1 0.4 GO:0003360 brainstem development(GO:0003360)
0.1 0.3 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.1 0.2 GO:0072034 renal vesicle induction(GO:0072034)
0.1 0.2 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 0.2 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.1 0.4 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 0.3 GO:0031642 negative regulation of myelination(GO:0031642)
0.1 0.2 GO:0044691 tooth eruption(GO:0044691)
0.1 0.3 GO:0006311 meiotic gene conversion(GO:0006311)
0.0 0.2 GO:0002501 MHC protein complex assembly(GO:0002396) peptide antigen assembly with MHC protein complex(GO:0002501)
0.0 0.2 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 0.2 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0 0.4 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.2 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.5 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.4 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.6 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.5 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.2 GO:0090095 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.0 0.2 GO:0048749 compound eye development(GO:0048749)
0.0 0.3 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.4 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.2 GO:0033504 floor plate development(GO:0033504)
0.0 0.8 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.3 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.1 GO:1902908 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) regulation of melanosome transport(GO:1902908) positive regulation of melanosome transport(GO:1902910)
0.0 0.3 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.0 0.3 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.0 0.4 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.1 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.0 0.1 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 0.2 GO:0021707 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) positive regulation of long term synaptic depression(GO:1900454)
0.0 0.1 GO:0032240 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.0 0.2 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.3 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.5 GO:0035878 nail development(GO:0035878)
0.0 0.2 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.1 GO:1902534 single-organism membrane invagination(GO:1902534)
0.0 0.2 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0 0.3 GO:0070459 prolactin secretion(GO:0070459)
0.0 0.6 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.1 GO:0045213 neurotransmitter receptor metabolic process(GO:0045213)
0.0 0.3 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.1 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 1.4 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.6 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.3 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.3 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.2 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.8 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 0.8 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.1 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.1 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.0 0.8 GO:2000637 positive regulation of gene silencing by miRNA(GO:2000637)
0.0 0.1 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.0 0.1 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.3 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.2 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.1 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.1 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.0 0.2 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.2 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.2 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.2 GO:0097338 response to clozapine(GO:0097338)
0.0 0.1 GO:0061568 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.0 0.3 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0 0.2 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.0 GO:0042040 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.3 GO:0010666 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.0 0.1 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0 0.2 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.1 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0 0.3 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.0 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.0 0.1 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.2 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 0.1 GO:2000672 regulation of motor neuron apoptotic process(GO:2000671) negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.3 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.1 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.1 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.2 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.1 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.2 GO:0031643 positive regulation of myelination(GO:0031643)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.2 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.2 GO:1904816 positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.0 0.5 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0 0.1 GO:0061055 myotome development(GO:0061055)
0.0 0.1 GO:0045144 meiotic sister chromatid segregation(GO:0045144)
0.0 0.2 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.2 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112)
0.0 0.2 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.1 GO:1900107 regulation of nodal signaling pathway(GO:1900107)
0.0 0.1 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.1 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.1 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.0 0.3 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.1 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.4 GO:1903432 regulation of TORC1 signaling(GO:1903432)
0.0 0.3 GO:0040020 regulation of meiotic nuclear division(GO:0040020)
0.0 0.2 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.0 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.2 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.1 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
0.0 0.2 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.2 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.1 GO:0060174 limb bud formation(GO:0060174)
0.0 0.1 GO:1900827 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0034457 Mpp10 complex(GO:0034457)
0.3 0.8 GO:0075341 host cell PML body(GO:0075341)
0.2 0.8 GO:0032301 MutSalpha complex(GO:0032301)
0.1 0.1 GO:0032302 MutSbeta complex(GO:0032302)
0.1 0.6 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.1 0.3 GO:1902737 dendritic filopodium(GO:1902737)
0.1 0.4 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 0.4 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
0.1 0.3 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.1 0.6 GO:0035061 interchromatin granule(GO:0035061)
0.1 0.8 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.1 0.7 GO:0001739 sex chromatin(GO:0001739)
0.1 0.3 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.1 0.6 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 0.3 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.2 GO:0005584 collagen type I trimer(GO:0005584)
0.0 0.2 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.4 GO:0070876 SOSS complex(GO:0070876)
0.0 0.3 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.0 0.3 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.8 GO:0000800 lateral element(GO:0000800)
0.0 0.3 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.1 GO:0031213 RSF complex(GO:0031213)
0.0 0.3 GO:0070847 core mediator complex(GO:0070847)
0.0 0.2 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.2 GO:0071458 polycystin complex(GO:0002133) integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.1 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.0 0.4 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.2 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.7 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.2 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.3 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.2 GO:0060203 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 0.3 GO:0000796 condensin complex(GO:0000796)
0.0 0.3 GO:0070652 HAUS complex(GO:0070652)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 1.1 GO:0043034 costamere(GO:0043034)
0.0 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.1 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.3 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.2 GO:0001940 male pronucleus(GO:0001940)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.3 GO:0043194 axon initial segment(GO:0043194)
0.0 0.3 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.3 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.1 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.3 GO:0031616 spindle pole centrosome(GO:0031616)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.2 0.5 GO:0030626 U12 snRNA binding(GO:0030626)
0.2 0.8 GO:0032143 single thymine insertion binding(GO:0032143)
0.1 0.1 GO:0032181 double-strand/single-strand DNA junction binding(GO:0000406) single guanine insertion binding(GO:0032142) dinucleotide repeat insertion binding(GO:0032181)
0.1 0.4 GO:0072591 citrate-L-glutamate ligase activity(GO:0072591)
0.1 0.6 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 1.0 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.9 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.1 1.3 GO:0033592 RNA strand annealing activity(GO:0033592)
0.1 0.3 GO:0051870 methotrexate binding(GO:0051870)
0.1 0.4 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.1 0.7 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.4 GO:0004641 phosphoribosylamine-glycine ligase activity(GO:0004637) phosphoribosylformylglycinamidine cyclo-ligase activity(GO:0004641) phosphoribosylglycinamide formyltransferase activity(GO:0004644)
0.1 0.3 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.1 0.3 GO:0032093 SAM domain binding(GO:0032093)
0.1 1.1 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.1 0.6 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.1 0.5 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1 0.4 GO:0000403 Y-form DNA binding(GO:0000403)
0.1 0.2 GO:0043398 HLH domain binding(GO:0043398)
0.1 1.0 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.1 0.4 GO:0034056 estrogen response element binding(GO:0034056)
0.1 0.3 GO:0071209 histone pre-mRNA DCP binding(GO:0071208) U7 snRNA binding(GO:0071209)
0.1 0.2 GO:0004817 cysteine-tRNA ligase activity(GO:0004817)
0.1 0.9 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.4 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 0.2 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.1 0.2 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.0 0.3 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.3 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.3 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.1 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.0 0.2 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.0 0.3 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502) all-trans retinal binding(GO:0005503)
0.0 0.3 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.1 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.7 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.9 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.2 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.4 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.2 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.2 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.4 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.7 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.1 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.1 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0016416 O-palmitoyltransferase activity(GO:0016416)
0.0 0.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.1 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.0 0.3 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.2 GO:0035197 siRNA binding(GO:0035197)
0.0 0.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.0 GO:0061598 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.4 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.1 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.0 0.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.4 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.1 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.5 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.9 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.2 PID ATR PATHWAY ATR signaling pathway
0.0 0.2 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.1 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.9 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.7 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.3 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.3 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.1 1.0 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 1.3 REACTOME LAGGING STRAND SYNTHESIS Genes involved in Lagging Strand Synthesis
0.0 0.8 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.7 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.0 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.1 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.7 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.8 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.6 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.0 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.2 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.4 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.6 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.7 REACTOME SIGNALING BY FGFR1 MUTANTS Genes involved in Signaling by FGFR1 mutants
0.0 0.4 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.4 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen