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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for E2F2_E2F5

Z-value: 1.53

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Transcription factors associated with E2F2_E2F5

Gene Symbol Gene ID Gene Info
ENSG00000007968.6 E2F transcription factor 2
ENSG00000133740.6 E2F transcription factor 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2F5hg19_v2_chr8_+_86099884_860999200.973.5e-02Click!
E2F2hg19_v2_chr1_-_23857698_23857733-0.732.7e-01Click!

Activity profile of E2F2_E2F5 motif

Sorted Z-values of E2F2_E2F5 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_27833034 1.32 ENST00000357320.2
histone cluster 1, H2al
chr6_+_27782788 0.76 ENST00000359465.4
histone cluster 1, H2bm
chr6_+_24775641 0.73 ENST00000378054.2
ENST00000476555.1
geminin, DNA replication inhibitor
chr1_-_91487013 0.64 ENST00000347275.5
ENST00000370440.1
zinc finger protein 644
chr11_-_19263145 0.63 ENST00000532666.1
ENST00000527884.1
E2F transcription factor 8
chr11_-_95522907 0.59 ENST00000358780.5
ENST00000542135.1
family with sequence similarity 76, member B
chr15_-_71184724 0.56 ENST00000560604.1
THAP domain containing 10
chr14_+_36295638 0.56 ENST00000543183.1
breast cancer metastasis-suppressor 1-like
chr11_-_95522639 0.52 ENST00000536839.1
family with sequence similarity 76, member B
chr18_+_19192228 0.48 ENST00000300413.5
ENST00000579618.1
ENST00000582475.1
small nuclear ribonucleoprotein D1 polypeptide 16kDa
chr1_+_228645796 0.48 ENST00000369160.2
histone cluster 3, H2bb
chrX_-_152736013 0.48 ENST00000330912.2
ENST00000338525.2
ENST00000334497.2
ENST00000370232.1
ENST00000370212.3
ENST00000370211.4
three prime repair exonuclease 2
HAUS augmin-like complex, subunit 7
chr11_-_57102947 0.44 ENST00000526696.1
structure specific recognition protein 1
chr1_-_26232522 0.44 ENST00000399728.1
stathmin 1
chr10_+_62538248 0.41 ENST00000448257.2
cyclin-dependent kinase 1
chr22_+_20105259 0.41 ENST00000416427.1
ENST00000421656.1
ENST00000423859.1
ENST00000418705.2
RAN binding protein 1
chr19_+_58694742 0.41 ENST00000597528.1
ENST00000594839.1
zinc finger protein 274
chr7_+_26241325 0.39 ENST00000456948.1
ENST00000409747.1
chromobox homolog 3
chr5_-_79950371 0.38 ENST00000511032.1
ENST00000504396.1
ENST00000505337.1
dihydrofolate reductase
chr19_+_8455200 0.38 ENST00000601897.1
ENST00000594216.1
RAB11B, member RAS oncogene family
chr3_+_10857885 0.38 ENST00000254488.2
ENST00000454147.1
solute carrier family 6 (neurotransmitter transporter), member 11
chr22_+_20105012 0.38 ENST00000331821.3
ENST00000411892.1
RAN binding protein 1
chr12_-_12849073 0.38 ENST00000332427.2
ENST00000540796.1
G protein-coupled receptor 19
chrX_-_45710920 0.37 ENST00000456532.1
RP5-1158E12.3
chr19_-_10305302 0.37 ENST00000592054.1
DNA (cytosine-5-)-methyltransferase 1
chr2_-_55277692 0.37 ENST00000394611.2
reticulon 4
chr5_-_36152031 0.37 ENST00000296603.4
LMBR1 domain containing 2
chr10_+_103912137 0.37 ENST00000603742.1
ENST00000488254.2
ENST00000461421.1
ENST00000476468.1
ENST00000370007.5
nucleolar and coiled-body phosphoprotein 1
chr2_-_203103281 0.36 ENST00000392244.3
ENST00000409181.1
ENST00000409712.1
ENST00000409498.2
ENST00000409368.1
ENST00000392245.1
ENST00000392246.2
small ubiquitin-like modifier 1
chr6_-_132272504 0.36 ENST00000367976.3
connective tissue growth factor
chr1_-_36235529 0.35 ENST00000318121.3
ENST00000373220.3
ENST00000520551.1
claspin
chr1_+_212782012 0.35 ENST00000341491.4
ENST00000366985.1
activating transcription factor 3
chr7_+_26241310 0.34 ENST00000396386.2
chromobox homolog 3
chr17_-_77179487 0.34 ENST00000580508.1
RNA binding protein, fox-1 homolog (C. elegans) 3
chr19_+_58694396 0.34 ENST00000326804.4
ENST00000345813.3
ENST00000424679.2
zinc finger protein 274
chr1_-_91487770 0.33 ENST00000337393.5
zinc finger protein 644
chr16_-_2827128 0.33 ENST00000494946.2
ENST00000409477.1
ENST00000572954.1
ENST00000262306.7
ENST00000409906.4
transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
chr2_-_136633940 0.33 ENST00000264156.2
minichromosome maintenance complex component 6
chr17_-_17184605 0.31 ENST00000268717.5
COP9 signalosome subunit 3
chr17_+_29158962 0.31 ENST00000321990.4
ATPase family, AAA domain containing 5
chr8_-_94928861 0.31 ENST00000607097.1
microRNA 378d-2
chr22_+_20104947 0.30 ENST00000402752.1
RAN binding protein 1
chr2_-_55277436 0.30 ENST00000354474.6
reticulon 4
chr20_+_5931275 0.29 ENST00000378896.3
ENST00000378883.1
minichromosome maintenance complex component 8
chr6_-_27114577 0.29 ENST00000356950.1
ENST00000396891.4
histone cluster 1, H2bk
chr1_-_212208842 0.29 ENST00000366992.3
ENST00000366993.3
ENST00000440600.2
ENST00000366994.3
integrator complex subunit 7
chr2_+_17935119 0.28 ENST00000317402.7
GEN1 Holliday junction 5' flap endonuclease
chr2_+_48010312 0.28 ENST00000540021.1
mutS homolog 6
chr1_-_91487806 0.28 ENST00000361321.5
zinc finger protein 644
chrX_-_135849484 0.27 ENST00000370620.1
ENST00000535227.1
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr13_+_114238997 0.27 ENST00000538138.1
ENST00000375370.5
transcription factor Dp-1
chr8_-_124408652 0.27 ENST00000287394.5
ATPase family, AAA domain containing 2
chr6_+_27775899 0.26 ENST00000358739.3
histone cluster 1, H2ai
chr11_-_95523500 0.26 ENST00000540054.1
family with sequence similarity 76, member B
chr11_-_19262486 0.25 ENST00000250024.4
E2F transcription factor 8
chr6_+_31633011 0.25 ENST00000375885.4
casein kinase 2, beta polypeptide
chr12_-_125398850 0.25 ENST00000535859.1
ENST00000546271.1
ENST00000540700.1
ENST00000546120.1
ubiquitin C
chr10_+_112327425 0.25 ENST00000361804.4
structural maintenance of chromosomes 3
chr1_-_36235559 0.25 ENST00000251195.5
claspin
chr17_+_42733803 0.25 ENST00000409122.2
chromosome 17 open reading frame 104
chr6_+_24775153 0.25 ENST00000356509.3
ENST00000230056.3
geminin, DNA replication inhibitor
chr1_+_6845497 0.24 ENST00000473578.1
ENST00000557126.1
calmodulin binding transcription activator 1
chr15_+_40987327 0.24 ENST00000423169.2
ENST00000267868.3
ENST00000557850.1
ENST00000532743.1
ENST00000382643.3
RAD51 recombinase
chr15_+_40987661 0.24 ENST00000526763.1
RAD51 recombinase
chr10_+_103911926 0.24 ENST00000605788.1
ENST00000405356.1
nucleolar and coiled-body phosphoprotein 1
chr3_-_44803141 0.24 ENST00000296121.4
KIAA1143
chr1_-_47779762 0.24 ENST00000371877.3
ENST00000360380.3
ENST00000337817.5
ENST00000447475.2
SCL/TAL1 interrupting locus
chr6_-_17706618 0.24 ENST00000262077.2
ENST00000537253.1
nucleoporin 153kDa
chrX_+_123095546 0.23 ENST00000371157.3
ENST00000371145.3
ENST00000371144.3
stromal antigen 2
chr20_+_5931497 0.23 ENST00000378886.2
ENST00000265187.4
minichromosome maintenance complex component 8
chr3_-_10028366 0.23 ENST00000429759.1
ER membrane protein complex subunit 3
chr7_-_6048702 0.23 ENST00000265849.7
PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
chr2_-_61108449 0.23 ENST00000439412.1
ENST00000452343.1
AC010733.4
chr6_+_116575329 0.22 ENST00000430252.2
ENST00000540275.1
ENST00000448740.2
dermatan sulfate epimerase
RP3-486I3.7
chr8_+_94929077 0.22 ENST00000297598.4
ENST00000520614.1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr4_+_55524085 0.22 ENST00000412167.2
ENST00000288135.5
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
chr7_-_105516923 0.22 ENST00000478915.1
ataxin 7-like 1
chr22_+_35653445 0.22 ENST00000420166.1
ENST00000444518.2
ENST00000455359.1
ENST00000216106.5
HMG box domain containing 4
chr4_+_71859156 0.21 ENST00000286648.5
ENST00000504730.1
ENST00000504952.1
deoxycytidine kinase
chr13_-_26625169 0.21 ENST00000319420.3
shisa family member 2
chr2_+_48010221 0.21 ENST00000234420.5
mutS homolog 6
chr2_-_203103185 0.21 ENST00000409205.1
small ubiquitin-like modifier 1
chrX_+_21959108 0.21 ENST00000457085.1
spermine synthase
chr2_-_232329186 0.20 ENST00000322723.4
nucleolin
chr20_-_5931109 0.20 ENST00000203001.2
tRNA methyltransferase 6 homolog (S. cerevisiae)
chr13_+_32889605 0.20 ENST00000380152.3
ENST00000544455.1
ENST00000530893.2
breast cancer 2, early onset
chr1_-_26233423 0.20 ENST00000357865.2
stathmin 1
chr9_-_123639304 0.20 ENST00000436309.1
PHD finger protein 19
chr19_+_35521699 0.20 ENST00000415950.3
sodium channel, voltage-gated, type I, beta subunit
chr8_+_94929168 0.20 ENST00000518107.1
ENST00000396200.3
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr1_-_26232951 0.20 ENST00000426559.2
ENST00000455785.2
stathmin 1
chr17_+_30264014 0.20 ENST00000322652.5
ENST00000580398.1
SUZ12 polycomb repressive complex 2 subunit
chr1_+_222885884 0.20 ENST00000340934.5
BRO1 domain and CAAX motif containing
chr5_+_138629389 0.20 ENST00000504045.1
ENST00000504311.1
ENST00000502499.1
matrin 3
chr15_+_100106244 0.19 ENST00000557942.1
myocyte enhancer factor 2A
chr2_+_174219548 0.19 ENST00000347703.3
ENST00000392567.2
ENST00000306721.3
ENST00000410101.3
ENST00000410019.3
cell division cycle associated 7
chr2_-_17935027 0.19 ENST00000446852.1
structural maintenance of chromosomes 6
chr11_-_64739358 0.19 ENST00000301896.5
ENST00000530444.1
chromosome 11 open reading frame 85
chr7_+_116593433 0.19 ENST00000323984.3
ENST00000393449.1
suppression of tumorigenicity 7
chr8_+_94929273 0.19 ENST00000518573.1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr2_+_238707388 0.19 ENST00000316997.4
RNA binding motif protein 44
chr6_+_135502408 0.19 ENST00000341911.5
ENST00000442647.2
ENST00000316528.8
v-myb avian myeloblastosis viral oncogene homolog
chr5_+_43121607 0.18 ENST00000509156.1
ENST00000508259.1
ENST00000306938.4
ENST00000399534.1
zinc finger protein 131
chr19_+_36705504 0.18 ENST00000456324.1
zinc finger protein 146
chrX_+_53449887 0.18 ENST00000375327.3
RIB43A domain with coiled-coils 1
chr2_-_17935059 0.18 ENST00000448223.2
ENST00000381272.4
ENST00000351948.4
structural maintenance of chromosomes 6
chr19_-_36705547 0.18 ENST00000304116.5
zinc finger protein 565
chr19_+_36706024 0.18 ENST00000443387.2
zinc finger protein 146
chr12_-_125399573 0.18 ENST00000339647.5
ubiquitin C
chr3_-_48229846 0.18 ENST00000302506.3
ENST00000351231.3
ENST00000437972.1
cell division cycle 25A
chr7_+_116593536 0.18 ENST00000417919.1
suppression of tumorigenicity 7
chr1_+_100598691 0.18 ENST00000370143.1
ENST00000370141.2
tRNA methyltransferase 13 homolog (S. cerevisiae)
chr3_-_136471204 0.18 ENST00000480733.1
ENST00000383202.2
ENST00000236698.5
ENST00000434713.2
stromal antigen 1
chr11_+_13299186 0.17 ENST00000527998.1
ENST00000396441.3
ENST00000533520.1
ENST00000529825.1
ENST00000389707.4
ENST00000401424.1
ENST00000529388.1
ENST00000530357.1
ENST00000403290.1
ENST00000361003.4
ENST00000389708.3
ENST00000403510.3
ENST00000482049.1
aryl hydrocarbon receptor nuclear translocator-like
chr5_+_43121698 0.17 ENST00000505606.2
ENST00000509634.1
ENST00000509341.1
zinc finger protein 131
chr7_+_116593568 0.17 ENST00000446490.1
suppression of tumorigenicity 7
chr13_+_115079949 0.17 ENST00000361283.1
chromosome alignment maintaining phosphoprotein 1
chr14_+_35452104 0.17 ENST00000216774.6
ENST00000546080.1
signal recognition particle 54kDa
chrX_+_46696372 0.17 ENST00000218340.3
retinitis pigmentosa 2 (X-linked recessive)
chr5_-_122759032 0.17 ENST00000510582.3
ENST00000328236.5
ENST00000306481.6
ENST00000508442.2
ENST00000395431.2
centrosomal protein 120kDa
chr11_+_9595180 0.17 ENST00000450114.2
WEE1 G2 checkpoint kinase
chr8_+_128748308 0.17 ENST00000377970.2
v-myc avian myelocytomatosis viral oncogene homolog
chr5_-_79950775 0.17 ENST00000439211.2
dihydrofolate reductase
chr6_-_52149475 0.16 ENST00000419835.2
ENST00000229854.7
ENST00000596288.1
minichromosome maintenance complex component 3
chr12_-_77459306 0.16 ENST00000547316.1
ENST00000416496.2
ENST00000550669.1
ENST00000322886.7
E2F transcription factor 7
chr11_-_59436453 0.16 ENST00000300146.9
protein associated with topoisomerase II homolog 1 (yeast)
chr9_-_99180597 0.16 ENST00000375256.4
zinc finger protein 367
chr20_-_35724388 0.16 ENST00000344359.3
ENST00000373664.3
retinoblastoma-like 1 (p107)
chr1_-_222885770 0.16 ENST00000355727.2
ENST00000340020.6
axin interactor, dorsalization associated
chr6_-_160210604 0.16 ENST00000420894.2
ENST00000539756.1
ENST00000544255.1
t-complex 1
chr3_+_14219858 0.16 ENST00000306024.3
LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr8_-_120868078 0.16 ENST00000313655.4
DNA replication and sister chromatid cohesion 1
chr7_+_90225796 0.16 ENST00000380050.3
cyclin-dependent kinase 14
chr15_+_71185148 0.16 ENST00000443425.2
ENST00000560755.1
leucine rich repeat containing 49
chr17_+_42733730 0.15 ENST00000359945.3
ENST00000425535.1
chromosome 17 open reading frame 104
chr7_-_148581251 0.15 ENST00000478654.1
ENST00000460911.1
ENST00000350995.2
enhancer of zeste homolog 2 (Drosophila)
chr10_+_96305610 0.15 ENST00000371332.4
ENST00000239026.6
helicase, lymphoid-specific
chr14_+_51706886 0.15 ENST00000457354.2
thioredoxin-related transmembrane protein 1
chr14_+_36295504 0.15 ENST00000216807.7
breast cancer metastasis-suppressor 1-like
chr3_+_41240925 0.15 ENST00000396183.3
ENST00000349496.5
ENST00000453024.1
catenin (cadherin-associated protein), beta 1, 88kDa
chr2_-_219433014 0.15 ENST00000418019.1
ENST00000454775.1
ENST00000338465.5
ENST00000415516.1
ENST00000258399.3
ubiquitin specific peptidase 37
chr7_-_559853 0.14 ENST00000405692.2
platelet-derived growth factor alpha polypeptide
chr17_-_73781567 0.14 ENST00000586607.1
H3 histone, family 3B (H3.3B)
chr7_+_94285637 0.14 ENST00000482108.1
ENST00000488574.1
paternally expressed 10
chr2_+_48541776 0.14 ENST00000413569.1
ENST00000340553.3
forkhead box N2
chr5_+_36876833 0.14 ENST00000282516.8
ENST00000448238.2
Nipped-B homolog (Drosophila)
chr6_-_144329531 0.14 ENST00000429150.1
ENST00000392309.1
ENST00000416623.1
ENST00000392307.1
pleiomorphic adenoma gene-like 1
chr7_+_116593292 0.14 ENST00000393446.2
ENST00000265437.5
ENST00000393451.3
suppression of tumorigenicity 7
chr7_+_120591170 0.14 ENST00000431467.1
inhibitor of growth family, member 3
chr7_-_148581360 0.14 ENST00000320356.2
ENST00000541220.1
ENST00000483967.1
ENST00000536783.1
enhancer of zeste homolog 2 (Drosophila)
chr1_+_222988464 0.14 ENST00000420335.1
RP11-452F19.3
chr7_+_26240776 0.14 ENST00000337620.4
chromobox homolog 3
chr15_+_100106126 0.14 ENST00000558812.1
ENST00000338042.6
myocyte enhancer factor 2A
chr8_-_67525473 0.14 ENST00000522677.3
v-myb avian myeloblastosis viral oncogene homolog-like 1
chr20_-_5931051 0.14 ENST00000453074.2
tRNA methyltransferase 6 homolog (S. cerevisiae)
chr2_-_96700664 0.14 ENST00000359548.4
ENST00000377137.3
ENST00000439254.1
ENST00000453542.1
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr4_+_72052964 0.14 ENST00000264485.5
ENST00000425175.1
solute carrier family 4 (sodium bicarbonate cotransporter), member 4
chrX_+_118708517 0.14 ENST00000346330.3
ubiquitin-conjugating enzyme E2A
chr13_-_73356009 0.14 ENST00000377780.4
ENST00000377767.4
DIS3 mitotic control homolog (S. cerevisiae)
chr1_-_23670817 0.13 ENST00000478691.1
heterogeneous nuclear ribonucleoprotein R
chr10_-_13390021 0.13 ENST00000537130.1
selenophosphate synthetase 1
chrX_+_118708493 0.13 ENST00000371558.2
ubiquitin-conjugating enzyme E2A
chr17_-_56065540 0.13 ENST00000583932.1
vascular endothelial zinc finger 1
chrX_+_131157322 0.13 ENST00000481105.1
ENST00000354719.6
ENST00000394335.2
Serine/threonine-protein kinase MST4
chrX_+_131157290 0.13 ENST00000394334.2
Serine/threonine-protein kinase MST4
chrX_+_24711997 0.13 ENST00000379068.3
ENST00000379059.3
polymerase (DNA directed), alpha 1, catalytic subunit
chr20_+_25388293 0.13 ENST00000262460.4
ENST00000429262.2
GINS complex subunit 1 (Psf1 homolog)
chr5_+_138629337 0.13 ENST00000394805.3
ENST00000512876.1
ENST00000513678.1
matrin 3
chr14_+_35452169 0.13 ENST00000555557.1
signal recognition particle 54kDa
chr1_-_243418344 0.13 ENST00000366542.1
centrosomal protein 170kDa
chr11_-_77705687 0.13 ENST00000529807.1
ENST00000527522.1
ENST00000534064.1
integrator complex subunit 4
chr1_-_23670813 0.13 ENST00000374612.1
heterogeneous nuclear ribonucleoprotein R
chr7_+_120590803 0.13 ENST00000315870.5
ENST00000339121.5
ENST00000445699.1
inhibitor of growth family, member 3
chrX_+_70798261 0.13 ENST00000373696.3
acidic repeat containing
chr17_+_7477040 0.13 ENST00000581384.1
ENST00000577929.1
eukaryotic translation initiation factor 4A1
chr1_-_229694406 0.12 ENST00000344517.4
ATP-binding cassette, sub-family B (MDR/TAP), member 10
chrX_-_53449593 0.12 ENST00000375340.6
ENST00000322213.4
structural maintenance of chromosomes 1A
chr14_-_50154921 0.12 ENST00000553805.2
ENST00000554396.1
ENST00000216367.5
ENST00000539565.2
polymerase (DNA directed), epsilon 2, accessory subunit
chr6_-_160210715 0.12 ENST00000392168.2
ENST00000321394.7
t-complex 1
chr7_+_94139105 0.12 ENST00000297273.4
CAS1 domain containing 1
chr4_+_72053017 0.12 ENST00000351898.6
solute carrier family 4 (sodium bicarbonate cotransporter), member 4
chr2_+_219433588 0.12 ENST00000295701.5
RCD1 required for cell differentiation1 homolog (S. pombe)
chr3_+_44803209 0.12 ENST00000326047.4
kinesin family member 15
chr22_+_42394780 0.12 ENST00000328823.9
WBP2 N-terminal like
chr17_+_58677539 0.12 ENST00000305921.3
protein phosphatase, Mg2+/Mn2+ dependent, 1D
chr15_+_80987617 0.12 ENST00000258884.4
ENST00000558464.1
abhydrolase domain containing 17C
chr5_+_93954358 0.12 ENST00000504099.1
ankyrin repeat domain 32
chr1_-_243418621 0.12 ENST00000366544.1
ENST00000366543.1
centrosomal protein 170kDa
chrX_-_131623982 0.11 ENST00000370844.1
muscleblind-like splicing regulator 3
chr3_-_133380731 0.11 ENST00000260810.5
topoisomerase (DNA) II binding protein 1
chr12_-_48499591 0.11 ENST00000551330.1
ENST00000004980.5
ENST00000339976.6
ENST00000448372.1
SUMO1/sentrin specific peptidase 1
chr12_-_122238464 0.11 ENST00000546227.1
ras homolog family member F (in filopodia)
chr11_+_74303612 0.11 ENST00000527458.1
ENST00000532497.1
ENST00000530511.1
polymerase (DNA-directed), delta 3, accessory subunit
chr12_-_81331460 0.11 ENST00000549417.1
lin-7 homolog A (C. elegans)
chr4_-_170679024 0.11 ENST00000393381.2
chromosome 4 open reading frame 27
chr12_-_133263893 0.11 ENST00000535270.1
ENST00000320574.5
polymerase (DNA directed), epsilon, catalytic subunit
chr6_-_27100529 0.11 ENST00000607124.1
ENST00000339812.2
ENST00000541790.1
histone cluster 1, H2bj
chr7_-_99699538 0.11 ENST00000343023.6
ENST00000303887.5
minichromosome maintenance complex component 7
chr4_-_130014532 0.11 ENST00000506368.1
ENST00000439369.2
ENST00000503215.1
sodium channel and clathrin linker 1
chr14_-_69864993 0.10 ENST00000555373.1
enhancer of rudimentary homolog (Drosophila)

Network of associatons between targets according to the STRING database.

First level regulatory network of E2F2_E2F5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.2 0.7 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.2 0.6 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.2 1.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 1.0 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.1 0.5 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.1 0.4 GO:0034059 response to anoxia(GO:0034059)
0.1 0.8 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 0.3 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.3 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.1 0.3 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.1 0.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.1 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 0.2 GO:0032240 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.1 0.9 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 0.3 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.1 0.3 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.1 0.2 GO:0038162 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) erythropoietin-mediated signaling pathway(GO:0038162)
0.1 0.3 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.2 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.1 0.3 GO:0006272 leading strand elongation(GO:0006272)
0.1 0.5 GO:0000710 meiotic mismatch repair(GO:0000710)
0.1 0.4 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
0.1 0.2 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 0.7 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.5 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.1 0.6 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.2 GO:0090095 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.0 0.1 GO:0061010 external genitalia morphogenesis(GO:0035261) gall bladder development(GO:0061010)
0.0 0.1 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.0 0.4 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.4 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.0 0.2 GO:0033504 floor plate development(GO:0033504)
0.0 0.7 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112)
0.0 0.1 GO:1904501 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.0 0.0 GO:0060266 respiratory burst involved in inflammatory response(GO:0002536) regulation of respiratory burst involved in inflammatory response(GO:0060264) negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.2 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.0 0.2 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.3 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 0.4 GO:0045054 constitutive secretory pathway(GO:0045054)
0.0 0.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.3 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.1 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.4 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.2 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0 0.3 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.1 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.0 0.1 GO:0071789 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.0 0.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.3 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.3 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.4 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.1 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.3 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.3 GO:1902969 mitotic DNA replication(GO:1902969)
0.0 0.2 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.0 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.0 0.1 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.0 0.2 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.1 GO:0044053 translocation of peptides or proteins into host(GO:0042000) translocation of peptides or proteins into host cell cytoplasm(GO:0044053) translocation of molecules into host(GO:0044417) translocation of peptides or proteins into other organism involved in symbiotic interaction(GO:0051808) translocation of molecules into other organism involved in symbiotic interaction(GO:0051836)
0.0 0.1 GO:0048478 replication fork protection(GO:0048478)
0.0 0.2 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.4 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0072396 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.0 0.3 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.1 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387) lung growth(GO:0060437)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.2 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.1 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.0 0.1 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.3 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.2 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.2 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.0 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.2 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.1 GO:0060591 chondroblast differentiation(GO:0060591)
0.0 0.2 GO:0034501 protein localization to kinetochore(GO:0034501)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 0.6 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.1 0.5 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.1 0.5 GO:0032301 MutSalpha complex(GO:0032301)
0.1 0.4 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.1 0.3 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.1 0.5 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.1 0.2 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.2 GO:0005873 plus-end kinesin complex(GO:0005873)
0.1 0.2 GO:0000811 GINS complex(GO:0000811)
0.1 0.9 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 0.4 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.2 GO:1990075 periciliary membrane compartment(GO:1990075)
0.0 0.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.3 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 0.3 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.1 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.7 GO:0000800 lateral element(GO:0000800)
0.0 0.3 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.5 GO:0070652 HAUS complex(GO:0070652)
0.0 0.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.1 GO:0031261 DNA replication preinitiation complex(GO:0031261)
0.0 0.2 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.2 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.3 GO:0033503 HULC complex(GO:0033503)
0.0 0.3 GO:0016589 NURF complex(GO:0016589)
0.0 1.0 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.4 GO:0032039 integrator complex(GO:0032039)
0.0 0.3 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.3 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.0 0.2 GO:0000796 condensin complex(GO:0000796)
0.0 0.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.8 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.0 0.7 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.2 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.4 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.1 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.0 0.1 GO:1990907 Scrib-APC-beta-catenin complex(GO:0034750) beta-catenin-TCF7L2 complex(GO:0070369) beta-catenin-TCF complex(GO:1990907)
0.0 0.1 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.0 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 0.2 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0051870 methotrexate binding(GO:0051870)
0.1 0.5 GO:0036033 mediator complex binding(GO:0036033)
0.1 0.5 GO:0032143 single thymine insertion binding(GO:0032143)
0.1 0.3 GO:0016768 spermine synthase activity(GO:0016768)
0.1 0.6 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 0.5 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 0.3 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.1 0.9 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 0.2 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.1 0.5 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.6 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.1 0.4 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.2 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.1 0.6 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 0.5 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.6 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.3 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.2 GO:0004137 deoxycytidine kinase activity(GO:0004137)
0.0 0.2 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.3 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 1.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.2 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.2 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.3 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.0 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
0.0 0.1 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.4 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.2 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.0 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.1 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.2 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 2.2 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.1 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.4 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0003688 DNA replication origin binding(GO:0003688)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.8 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.6 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 2.1 PID E2F PATHWAY E2F transcription factor network
0.0 1.6 PID P75 NTR PATHWAY p75(NTR)-mediated signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.2 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.7 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.3 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.6 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.6 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.8 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.2 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.5 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 1.2 REACTOME RNA POL I TRANSCRIPTION Genes involved in RNA Polymerase I Transcription
0.0 0.5 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.2 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.1 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling