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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for DUXA

Z-value: 1.46

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Transcription factors associated with DUXA

Gene Symbol Gene ID Gene Info
DUXA
ENSG00000258873.2 double homeobox A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
DUXAhg19_v2_chr19_-_57678811_576788110.544.6e-01Click!

Activity profile of DUXA motif

Sorted Z-values of DUXA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_91546926 1.15 ENST00000550758.1
DCN
decorin
chr1_-_168464875 0.90 ENST00000422253.1
RP5-968D22.3
RP5-968D22.3
chr3_+_159943362 0.81 ENST00000326474.3
C3orf80
chromosome 3 open reading frame 80
chr4_+_156775910 0.72 ENST00000506072.1
ENST00000507590.1
TDO2
tryptophan 2,3-dioxygenase
chr7_+_30589829 0.72 ENST00000579437.1
RP4-777O23.1
RP4-777O23.1
chr1_+_95616933 0.70 ENST00000604203.1
RP11-57H12.6
TMEM56-RWDD3 readthrough
chr6_+_28092338 0.62 ENST00000340487.4
ZSCAN16
zinc finger and SCAN domain containing 16
chr16_-_57219926 0.59 ENST00000566584.1
ENST00000566481.1
ENST00000566077.1
ENST00000564108.1
ENST00000565458.1
ENST00000566681.1
ENST00000567439.1
FAM192A
family with sequence similarity 192, member A
chr8_-_86575726 0.58 ENST00000379010.2
REXO1L1
REX1, RNA exonuclease 1 homolog (S. cerevisiae)-like 1, pseudogene
chr2_+_242913327 0.56 ENST00000426962.1
AC093642.3
AC093642.3
chr2_-_69180083 0.54 ENST00000328895.4
GKN2
gastrokine 2
chr3_+_118892411 0.50 ENST00000479520.1
ENST00000494855.1
UPK1B
uroplakin 1B
chr8_+_92114060 0.50 ENST00000518304.1
LRRC69
leucine rich repeat containing 69
chr16_+_53412368 0.50 ENST00000565189.1
RP11-44F14.2
RP11-44F14.2
chr6_+_86195088 0.48 ENST00000437581.1
NT5E
5'-nucleotidase, ecto (CD73)
chr2_+_86333340 0.48 ENST00000409783.2
ENST00000409277.3
PTCD3
pentatricopeptide repeat domain 3
chr16_-_57219721 0.47 ENST00000562406.1
ENST00000568671.1
ENST00000567044.1
FAM192A
family with sequence similarity 192, member A
chr14_+_21566980 0.45 ENST00000418511.2
ENST00000554329.2
TMEM253
transmembrane protein 253
chr10_-_112064665 0.44 ENST00000369603.5
SMNDC1
survival motor neuron domain containing 1
chr10_-_112255945 0.44 ENST00000609514.1
ENST00000607952.1
RP11-525A16.4
RP11-525A16.4
chrX_-_55187531 0.43 ENST00000489298.1
ENST00000477847.2
FAM104B
family with sequence similarity 104, member B
chr11_-_95523500 0.43 ENST00000540054.1
FAM76B
family with sequence similarity 76, member B
chr7_+_141490017 0.40 ENST00000247883.4
TAS2R5
taste receptor, type 2, member 5
chr1_+_40997233 0.40 ENST00000372699.3
ENST00000372697.3
ENST00000372696.3
ZNF684
zinc finger protein 684
chr11_+_10772847 0.40 ENST00000524523.1
CTR9
CTR9, Paf1/RNA polymerase II complex component
chr2_-_114461655 0.40 ENST00000424612.1
AC017074.2
AC017074.2
chr6_+_168434678 0.40 ENST00000496008.1
KIF25
kinesin family member 25
chr12_-_75784669 0.39 ENST00000552497.1
ENST00000551829.1
ENST00000436898.1
ENST00000442339.2
CAPS2
calcyphosine 2
chr15_+_71228826 0.39 ENST00000558456.1
ENST00000560158.2
ENST00000558808.1
ENST00000559806.1
ENST00000559069.1
LRRC49
leucine rich repeat containing 49
chr11_+_10772534 0.39 ENST00000361367.2
CTR9
CTR9, Paf1/RNA polymerase II complex component
chr4_+_77941685 0.37 ENST00000506731.1
SEPT11
septin 11
chrX_-_46759138 0.37 ENST00000377879.3
CXorf31
chromosome X open reading frame 31
chr15_+_101402041 0.37 ENST00000558475.1
ENST00000558641.1
ENST00000559673.1
RP11-66B24.1
RP11-66B24.1
chr4_+_76649797 0.37 ENST00000538159.1
ENST00000514213.2
USO1
USO1 vesicle transport factor
chr10_+_180643 0.36 ENST00000509513.2
ENST00000397959.3
ZMYND11
zinc finger, MYND-type containing 11
chr5_-_152069089 0.36 ENST00000506723.2
AC091969.1
AC091969.1
chr3_+_107364769 0.35 ENST00000449271.1
ENST00000425868.1
ENST00000449213.1
BBX
bobby sox homolog (Drosophila)
chr4_+_79567057 0.34 ENST00000503259.1
ENST00000507802.1
RP11-792D21.2
long intergenic non-protein coding RNA 1094
chr21_+_18811205 0.34 ENST00000440664.1
C21orf37
chromosome 21 open reading frame 37
chrX_+_149867681 0.34 ENST00000438018.1
ENST00000436701.1
MTMR1
myotubularin related protein 1
chr4_-_190948409 0.34 ENST00000504750.1
ENST00000378763.1
FRG2
FSHD region gene 2
chr2_+_149632783 0.33 ENST00000435030.1
KIF5C
kinesin family member 5C
chr11_-_11374904 0.32 ENST00000528848.2
CSNK2A3
casein kinase 2, alpha 3 polypeptide
chr3_+_120461484 0.32 ENST00000484715.1
ENST00000469772.1
ENST00000283875.5
ENST00000492959.1
GTF2E1
general transcription factor IIE, polypeptide 1, alpha 56kDa
chr11_+_13690249 0.32 ENST00000532701.1
FAR1
fatty acyl CoA reductase 1
chr12_-_118628350 0.32 ENST00000537952.1
ENST00000537822.1
TAOK3
TAO kinase 3
chr5_-_31532238 0.32 ENST00000507438.1
DROSHA
drosha, ribonuclease type III
chr8_+_19796381 0.32 ENST00000524029.1
ENST00000522701.1
ENST00000311322.8
LPL
lipoprotein lipase
chr19_-_54663473 0.32 ENST00000222224.3
LENG1
leukocyte receptor cluster (LRC) member 1
chr1_+_170501270 0.31 ENST00000367763.3
ENST00000367762.1
GORAB
golgin, RAB6-interacting
chr21_+_17566643 0.31 ENST00000419952.1
ENST00000445461.2
LINC00478
long intergenic non-protein coding RNA 478
chr5_+_68513622 0.31 ENST00000512880.1
ENST00000602380.1
MRPS36
mitochondrial ribosomal protein S36
chrX_-_55187588 0.31 ENST00000472571.2
ENST00000332132.4
ENST00000425133.2
ENST00000358460.4
FAM104B
family with sequence similarity 104, member B
chr12_+_32115400 0.31 ENST00000381054.3
KIAA1551
KIAA1551
chr16_-_15149917 0.30 ENST00000287706.3
NTAN1
N-terminal asparagine amidase
chr17_-_79849438 0.30 ENST00000331204.4
ENST00000505490.2
ALYREF
Aly/REF export factor
chr19_+_52932435 0.30 ENST00000301085.4
ZNF534
zinc finger protein 534
chr18_-_2982869 0.30 ENST00000584915.1
LPIN2
lipin 2
chr8_+_86747543 0.29 ENST00000425429.2
REXO1L11P
REX1, RNA exonuclease 1 homolog (S. cerevisiae)-like 11, pseudogene
chr17_+_66511540 0.29 ENST00000588188.2
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr9_-_6015607 0.29 ENST00000259569.5
RANBP6
RAN binding protein 6
chr2_-_24299308 0.28 ENST00000233468.4
SF3B14
Pre-mRNA branch site protein p14
chr2_+_208527094 0.28 ENST00000429730.1
AC079767.4
AC079767.4
chr6_-_10838736 0.28 ENST00000536370.1
ENST00000474039.1
MAK
male germ cell-associated kinase
chr12_-_54653313 0.28 ENST00000550411.1
ENST00000439541.2
CBX5
chromobox homolog 5
chr5_-_74326724 0.28 ENST00000322348.4
GCNT4
glucosaminyl (N-acetyl) transferase 4, core 2
chr2_+_101437487 0.28 ENST00000427413.1
ENST00000542504.1
NPAS2
neuronal PAS domain protein 2
chr13_+_21141270 0.27 ENST00000319980.6
ENST00000537103.1
ENST00000389373.3
IFT88
intraflagellar transport 88 homolog (Chlamydomonas)
chr10_-_33281363 0.27 ENST00000534049.1
ITGB1
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
chr2_+_29001711 0.27 ENST00000418910.1
PPP1CB
protein phosphatase 1, catalytic subunit, beta isozyme
chr13_+_21141208 0.27 ENST00000351808.5
IFT88
intraflagellar transport 88 homolog (Chlamydomonas)
chr5_+_154238149 0.27 ENST00000519430.1
ENST00000520671.1
ENST00000521583.1
ENST00000518028.1
ENST00000519404.1
ENST00000519394.1
ENST00000518775.1
CNOT8
CCR4-NOT transcription complex, subunit 8
chr5_+_67535647 0.27 ENST00000520675.1
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr1_-_220219775 0.27 ENST00000609181.1
EPRS
glutamyl-prolyl-tRNA synthetase
chr11_-_95522907 0.27 ENST00000358780.5
ENST00000542135.1
FAM76B
family with sequence similarity 76, member B
chr9_-_75695323 0.26 ENST00000419959.1
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr1_-_115124257 0.26 ENST00000369541.3
BCAS2
breast carcinoma amplified sequence 2
chr6_-_75953484 0.26 ENST00000472311.2
ENST00000460985.1
ENST00000377978.3
ENST00000509698.1
ENST00000230459.4
ENST00000370089.2
COX7A2
cytochrome c oxidase subunit VIIa polypeptide 2 (liver)
chr12_+_111284764 0.26 ENST00000545036.1
ENST00000308208.5
CCDC63
coiled-coil domain containing 63
chr6_-_26199499 0.26 ENST00000377831.5
HIST1H3D
histone cluster 1, H3d
chr4_+_148653206 0.26 ENST00000336498.3
ARHGAP10
Rho GTPase activating protein 10
chr5_+_142149932 0.25 ENST00000274498.4
ARHGAP26
Rho GTPase activating protein 26
chrX_+_154444643 0.25 ENST00000286428.5
VBP1
von Hippel-Lindau binding protein 1
chr3_+_107364683 0.25 ENST00000413213.1
BBX
bobby sox homolog (Drosophila)
chr15_-_75918787 0.25 ENST00000564086.1
SNUPN
snurportin 1
chr4_-_14889791 0.25 ENST00000509654.1
ENST00000515031.1
ENST00000505089.2
LINC00504
long intergenic non-protein coding RNA 504
chr1_-_45272951 0.25 ENST00000372200.1
TCTEX1D4
Tctex1 domain containing 4
chr4_-_110651143 0.24 ENST00000243501.5
PLA2G12A
phospholipase A2, group XIIA
chr11_+_114270752 0.24 ENST00000540163.1
RBM7
RNA binding motif protein 7
chr5_+_140079919 0.24 ENST00000274712.3
ZMAT2
zinc finger, matrin-type 2
chr9_+_88556444 0.24 ENST00000376040.1
NAA35
N(alpha)-acetyltransferase 35, NatC auxiliary subunit
chr12_+_25348186 0.24 ENST00000555711.1
ENST00000556885.1
ENST00000554266.1
ENST00000556351.1
ENST00000556927.1
ENST00000556402.1
ENST00000553788.1
LYRM5
LYR motif containing 5
chr11_-_47736896 0.23 ENST00000525123.1
ENST00000528244.1
ENST00000532595.1
ENST00000529154.1
ENST00000530969.1
AGBL2
ATP/GTP binding protein-like 2
chr12_+_25348139 0.23 ENST00000557540.2
ENST00000381356.4
LYRM5
LYR motif containing 5
chr18_-_74839891 0.23 ENST00000581878.1
MBP
myelin basic protein
chr5_+_68513557 0.23 ENST00000256441.4
MRPS36
mitochondrial ribosomal protein S36
chr2_+_109223595 0.23 ENST00000410093.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr5_-_89705537 0.23 ENST00000522864.1
ENST00000522083.1
ENST00000522565.1
ENST00000522842.1
ENST00000283122.3
CETN3
centrin, EF-hand protein, 3
chr8_+_11225911 0.23 ENST00000284481.3
C8orf12
chromosome 8 open reading frame 12
chr3_-_39321512 0.22 ENST00000399220.2
CX3CR1
chemokine (C-X3-C motif) receptor 1
chr19_+_32836499 0.22 ENST00000311921.4
ENST00000544431.1
ENST00000355898.5
ZNF507
zinc finger protein 507
chr6_+_31939608 0.22 ENST00000375331.2
ENST00000375333.2
STK19
serine/threonine kinase 19
chr15_+_58724184 0.22 ENST00000433326.2
LIPC
lipase, hepatic
chr10_-_29811456 0.22 ENST00000535393.1
SVIL
supervillin
chr7_-_99277610 0.22 ENST00000343703.5
ENST00000222982.4
ENST00000439761.1
ENST00000339843.2
CYP3A5
cytochrome P450, family 3, subfamily A, polypeptide 5
chr2_-_201753717 0.22 ENST00000409264.2
PPIL3
peptidylprolyl isomerase (cyclophilin)-like 3
chr20_-_44298878 0.22 ENST00000324384.3
ENST00000356562.2
WFDC11
WAP four-disulfide core domain 11
chr2_-_198062758 0.22 ENST00000328737.2
ANKRD44
ankyrin repeat domain 44
chr1_+_219347203 0.21 ENST00000366927.3
LYPLAL1
lysophospholipase-like 1
chr1_-_198906528 0.21 ENST00000432296.1
MIR181A1HG
MIR181A1 host gene (non-protein coding)
chr6_+_97010424 0.21 ENST00000541107.1
ENST00000450218.1
ENST00000326771.2
FHL5
four and a half LIM domains 5
chrX_-_115085422 0.21 ENST00000430756.2
RP11-761E20.1
RP11-761E20.1
chr15_-_80263506 0.21 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chr3_-_176914191 0.21 ENST00000437738.1
ENST00000424913.1
ENST00000443315.1
TBL1XR1
transducin (beta)-like 1 X-linked receptor 1
chr11_-_89653576 0.21 ENST00000420869.1
TRIM49D1
tripartite motif containing 49D1
chr4_-_76649546 0.21 ENST00000508510.1
ENST00000509561.1
ENST00000499709.2
ENST00000511868.1
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr5_+_145826867 0.21 ENST00000296702.5
ENST00000394421.2
TCERG1
transcription elongation regulator 1
chr5_+_32585605 0.20 ENST00000265073.4
ENST00000515355.1
ENST00000502897.1
ENST00000510442.1
SUB1
SUB1 homolog (S. cerevisiae)
chr8_-_16859690 0.20 ENST00000180166.5
FGF20
fibroblast growth factor 20
chr1_-_91487770 0.20 ENST00000337393.5
ZNF644
zinc finger protein 644
chr3_+_190333097 0.20 ENST00000412080.1
IL1RAP
interleukin 1 receptor accessory protein
chr16_-_57219966 0.20 ENST00000565760.1
ENST00000309137.8
ENST00000570184.1
ENST00000562324.1
FAM192A
family with sequence similarity 192, member A
chr8_+_91233744 0.20 ENST00000524361.1
LINC00534
long intergenic non-protein coding RNA 534
chr20_-_17539456 0.20 ENST00000544874.1
ENST00000377868.2
BFSP1
beaded filament structural protein 1, filensin
chr11_+_121447469 0.19 ENST00000532694.1
ENST00000534286.1
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr1_-_42801540 0.19 ENST00000372573.1
FOXJ3
forkhead box J3
chr16_+_30007524 0.19 ENST00000567254.1
ENST00000567705.1
INO80E
INO80 complex subunit E
chr6_+_3259148 0.19 ENST00000419065.2
ENST00000473000.2
ENST00000451246.2
ENST00000454610.2
PSMG4
proteasome (prosome, macropain) assembly chaperone 4
chr2_+_60983361 0.19 ENST00000238714.3
PAPOLG
poly(A) polymerase gamma
chr1_-_91487806 0.19 ENST00000361321.5
ZNF644
zinc finger protein 644
chr19_-_6393216 0.19 ENST00000595047.1
GTF2F1
general transcription factor IIF, polypeptide 1, 74kDa
chr16_+_57220193 0.18 ENST00000564435.1
ENST00000562959.1
ENST00000394420.4
ENST00000568505.2
ENST00000537866.1
RSPRY1
ring finger and SPRY domain containing 1
chr12_-_110434021 0.18 ENST00000355312.3
ENST00000551209.1
ENST00000550186.1
GIT2
G protein-coupled receptor kinase interacting ArfGAP 2
chr5_-_31532160 0.18 ENST00000511367.2
ENST00000513349.1
DROSHA
drosha, ribonuclease type III
chr5_+_142149955 0.18 ENST00000378004.3
ARHGAP26
Rho GTPase activating protein 26
chr16_+_24549014 0.18 ENST00000564314.1
ENST00000567686.1
RBBP6
retinoblastoma binding protein 6
chr6_-_10838710 0.18 ENST00000313243.2
MAK
male germ cell-associated kinase
chr12_-_68845165 0.18 ENST00000360485.3
ENST00000441255.2
RP11-81H14.2
RP11-81H14.2
chr14_-_102552659 0.18 ENST00000441629.2
HSP90AA1
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr4_-_77069573 0.18 ENST00000264883.3
NUP54
nucleoporin 54kDa
chrX_-_48980098 0.17 ENST00000156109.5
GPKOW
G patch domain and KOW motifs
chr2_+_201994042 0.17 ENST00000417748.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr11_+_95523621 0.17 ENST00000325542.5
ENST00000325486.5
ENST00000544522.1
ENST00000541365.1
CEP57
centrosomal protein 57kDa
chr3_+_157827841 0.17 ENST00000295930.3
ENST00000471994.1
ENST00000464171.1
ENST00000312179.6
ENST00000475278.2
RSRC1
arginine/serine-rich coiled-coil 1
chr12_+_122688090 0.17 ENST00000324189.4
ENST00000546192.1
B3GNT4
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
chr15_-_66679019 0.17 ENST00000568216.1
ENST00000562124.1
ENST00000570251.1
TIPIN
TIMELESS interacting protein
chr11_+_13690200 0.17 ENST00000354817.3
FAR1
fatty acyl CoA reductase 1
chr4_-_170924888 0.17 ENST00000502832.1
ENST00000393704.3
MFAP3L
microfibrillar-associated protein 3-like
chr3_+_118892362 0.16 ENST00000497685.1
ENST00000264234.3
UPK1B
uroplakin 1B
chr16_+_31724552 0.16 ENST00000539915.1
ENST00000316491.9
ENST00000399681.3
ENST00000398696.3
ENST00000534369.1
ZNF720
zinc finger protein 720
chr3_-_138725110 0.16 ENST00000383163.2
PRR23A
proline rich 23A
chr16_-_21875424 0.16 ENST00000541674.1
NPIPB4
nuclear pore complex interacting protein family, member B4
chr14_-_75536182 0.16 ENST00000555463.1
ACYP1
acylphosphatase 1, erythrocyte (common) type
chr5_+_154238042 0.16 ENST00000519211.1
ENST00000522458.1
ENST00000519903.1
ENST00000521450.1
ENST00000403027.2
CNOT8
CCR4-NOT transcription complex, subunit 8
chr12_-_118796971 0.16 ENST00000542902.1
TAOK3
TAO kinase 3
chr6_+_74104566 0.16 ENST00000539829.1
DDX43
DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
chr1_-_154941350 0.16 ENST00000444179.1
ENST00000414115.1
SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr13_+_20207782 0.16 ENST00000414242.2
ENST00000361479.5
MPHOSPH8
M-phase phosphoprotein 8
chr9_-_13279563 0.16 ENST00000541718.1
MPDZ
multiple PDZ domain protein
chr2_+_197577841 0.16 ENST00000409270.1
CCDC150
coiled-coil domain containing 150
chr14_+_55595762 0.16 ENST00000254301.9
LGALS3
lectin, galactoside-binding, soluble, 3
chr1_+_209929494 0.16 ENST00000367026.3
TRAF3IP3
TRAF3 interacting protein 3
chr15_-_38519066 0.16 ENST00000561320.1
ENST00000561161.1
RP11-346D14.1
RP11-346D14.1
chr17_+_61151306 0.16 ENST00000580068.1
ENST00000580466.1
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr12_+_27619743 0.16 ENST00000298876.4
ENST00000416383.1
SMCO2
single-pass membrane protein with coiled-coil domains 2
chr8_+_82192501 0.16 ENST00000297258.6
FABP5
fatty acid binding protein 5 (psoriasis-associated)
chr4_+_40751914 0.15 ENST00000381782.2
ENST00000316607.5
NSUN7
NOP2/Sun domain family, member 7
chrX_+_77166172 0.15 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATP7A
ATPase, Cu++ transporting, alpha polypeptide
chr1_+_104159999 0.15 ENST00000414303.2
ENST00000423678.1
AMY2A
amylase, alpha 2A (pancreatic)
chr3_+_107318157 0.15 ENST00000406780.1
BBX
bobby sox homolog (Drosophila)
chr12_-_110434183 0.15 ENST00000360185.4
ENST00000354574.4
ENST00000338373.5
ENST00000343646.5
ENST00000356259.4
ENST00000553118.1
GIT2
G protein-coupled receptor kinase interacting ArfGAP 2
chrX_-_148571884 0.14 ENST00000537071.1
IDS
iduronate 2-sulfatase
chr10_+_47894572 0.14 ENST00000355876.5
FAM21B
family with sequence similarity 21, member B
chr3_+_179280668 0.14 ENST00000429709.2
ENST00000450518.2
ENST00000392662.1
ENST00000490364.1
ACTL6A
actin-like 6A
chr4_-_74088800 0.14 ENST00000509867.2
ANKRD17
ankyrin repeat domain 17
chr15_+_44719970 0.14 ENST00000558966.1
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr6_+_150920999 0.14 ENST00000367328.1
ENST00000367326.1
PLEKHG1
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr15_+_98503922 0.14 ENST00000268042.6
ARRDC4
arrestin domain containing 4
chr7_+_77325738 0.14 ENST00000334955.8
RSBN1L
round spermatid basic protein 1-like
chr12_+_57157100 0.14 ENST00000322165.1
HSD17B6
hydroxysteroid (17-beta) dehydrogenase 6
chr5_+_154238096 0.14 ENST00000517568.1
ENST00000524105.1
ENST00000285896.6
CNOT8
CCR4-NOT transcription complex, subunit 8
chr18_+_19192228 0.14 ENST00000300413.5
ENST00000579618.1
ENST00000582475.1
SNRPD1
small nuclear ribonucleoprotein D1 polypeptide 16kDa
chr13_-_81801115 0.14 ENST00000567258.1
LINC00564
long intergenic non-protein coding RNA 564
chr1_+_92632542 0.14 ENST00000409154.4
ENST00000370378.4
KIAA1107
KIAA1107
chr12_+_26164645 0.14 ENST00000542004.1
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr14_-_61447752 0.13 ENST00000555420.1
ENST00000553903.1
TRMT5
tRNA methyltransferase 5
chr8_+_91233711 0.13 ENST00000523283.1
ENST00000517400.1
LINC00534
long intergenic non-protein coding RNA 534
chr11_+_43333513 0.13 ENST00000534695.1
ENST00000455725.2
ENST00000531273.1
ENST00000420461.2
ENST00000378852.3
ENST00000534600.1
API5
apoptosis inhibitor 5
chr4_-_6557336 0.13 ENST00000507294.1
PPP2R2C
protein phosphatase 2, regulatory subunit B, gamma
chr12_-_114211474 0.13 ENST00000550905.1
ENST00000547963.1
RP11-438N16.1
RP11-438N16.1
chr8_-_62602327 0.13 ENST00000445642.3
ENST00000517847.2
ENST00000389204.4
ENST00000517661.1
ENST00000517903.1
ENST00000522603.1
ENST00000522349.1
ENST00000522835.1
ENST00000541428.1
ENST00000518306.1
ASPH
aspartate beta-hydroxylase
chr5_-_1882858 0.13 ENST00000511126.1
ENST00000231357.2
IRX4
iroquois homeobox 4
chr13_-_31191642 0.13 ENST00000405805.1
HMGB1
high mobility group box 1
chr5_+_31532373 0.13 ENST00000325366.9
ENST00000355907.3
ENST00000507818.2
C5orf22
chromosome 5 open reading frame 22
chr10_-_48806939 0.13 ENST00000374233.3
ENST00000507417.1
ENST00000512321.1
ENST00000395660.2
ENST00000374235.2
ENST00000395661.3
PTPN20B
protein tyrosine phosphatase, non-receptor type 20B
chr7_+_8008418 0.13 ENST00000223145.5
GLCCI1
glucocorticoid induced transcript 1
chr9_-_19065082 0.13 ENST00000415524.1
HAUS6
HAUS augmin-like complex, subunit 6
chr6_-_76072719 0.13 ENST00000370020.1
FILIP1
filamin A interacting protein 1
chr12_+_8662057 0.13 ENST00000382064.2
CLEC4D
C-type lectin domain family 4, member D
chr12_-_110434096 0.13 ENST00000320063.9
ENST00000457474.2
ENST00000547815.1
ENST00000361006.5
GIT2
G protein-coupled receptor kinase interacting ArfGAP 2

Network of associatons between targets according to the STRING database.

First level regulatory network of DUXA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2 0.8 GO:2001162 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.2 0.7 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.1 0.4 GO:0006433 glutamyl-tRNA aminoacylation(GO:0006424) prolyl-tRNA aminoacylation(GO:0006433)
0.1 0.3 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.1 0.5 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.1 0.5 GO:0046086 adenosine biosynthetic process(GO:0046086)
0.1 0.3 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.1 0.2 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.1 0.2 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.1 0.5 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.1 0.2 GO:1902769 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.1 0.2 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.2 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.3 GO:0010710 regulation of collagen catabolic process(GO:0010710)
0.0 0.2 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.2 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.0 0.3 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.2 GO:0061015 snRNA import into nucleus(GO:0061015)
0.0 0.2 GO:0051541 elastin metabolic process(GO:0051541) cellular response to lead ion(GO:0071284)
0.0 0.2 GO:0043335 protein unfolding(GO:0043335)
0.0 0.1 GO:0006710 androgen catabolic process(GO:0006710)
0.0 0.2 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.5 GO:2000628 production of siRNA involved in RNA interference(GO:0030422) regulation of miRNA metabolic process(GO:2000628)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.1 GO:0035711 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) T-helper 1 cell activation(GO:0035711) negative regulation of apoptotic cell clearance(GO:2000426)
0.0 0.1 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.1 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.2 GO:2000521 positive regulation of mononuclear cell migration(GO:0071677) negative regulation of immunological synapse formation(GO:2000521)
0.0 0.2 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.2 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.1 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.1 GO:0060979 transforming growth factor beta receptor complex assembly(GO:0007181) vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.1 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.0 0.1 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.2 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.0 0.1 GO:0046356 acetyl-CoA catabolic process(GO:0046356)
0.0 0.1 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.0 0.2 GO:0048478 replication fork protection(GO:0048478)
0.0 0.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.0 0.3 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.3 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.2 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.2 GO:1902856 negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.0 0.1 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.1 GO:0018032 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.0 0.8 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.0 0.4 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.3 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.5 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0 0.3 GO:1901620 regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901620)
0.0 0.2 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.1 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.2 GO:0060613 fat pad development(GO:0060613)
0.0 0.1 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.0 0.1 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.2 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.0 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0 0.3 GO:0051775 response to redox state(GO:0051775)
0.0 0.3 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.2 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.0 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.1 GO:0031947 negative regulation of glucocorticoid metabolic process(GO:0031944) negative regulation of glucocorticoid biosynthetic process(GO:0031947) negative regulation of steroid hormone biosynthetic process(GO:0090032)
0.0 0.3 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.0 0.5 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:1903095 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.2 1.1 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.3 GO:0034677 integrin alpha7-beta1 complex(GO:0034677)
0.1 0.5 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1 0.8 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 0.8 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.2 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.0 0.2 GO:0031417 NatC complex(GO:0031417)
0.0 0.3 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.4 GO:0097452 GAIT complex(GO:0097452)
0.0 0.3 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.3 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.4 GO:0042587 glycogen granule(GO:0042587)
0.0 0.3 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.2 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 0.3 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.5 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.2 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.1 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.3 GO:0042627 chylomicron(GO:0042627)
0.0 0.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.0 GO:1990032 parallel fiber(GO:1990032)
0.0 0.3 GO:0000346 transcription export complex(GO:0000346)
0.0 0.5 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.2 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.4 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.0 GO:0005879 axonemal microtubule(GO:0005879)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1 0.4 GO:0004827 glutamate-tRNA ligase activity(GO:0004818) proline-tRNA ligase activity(GO:0004827)
0.1 0.3 GO:0017129 triglyceride binding(GO:0017129)
0.1 0.5 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1 0.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 0.5 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1 0.2 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
0.1 0.3 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 0.3 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 0.3 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0004423 iduronate-2-sulfatase activity(GO:0004423)
0.0 0.1 GO:0070123 transforming growth factor beta receptor activity, type III(GO:0070123)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.3 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.0 0.2 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532) copper-dependent protein binding(GO:0032767)
0.0 0.2 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.2 GO:0019863 IgE binding(GO:0019863)
0.0 0.3 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.2 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.0 0.7 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.0 0.5 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.4 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.4 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.4 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.8 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.1 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.1 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.0 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.0 1.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.2 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.0 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.2 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.0 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.2 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.3 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.2 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.3 GO:0017134 fibroblast growth factor binding(GO:0017134)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.8 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 0.2 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.7 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.5 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.2 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.8 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.5 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.6 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism