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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for DMC1

Z-value: 0.49

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Transcription factors associated with DMC1

Gene Symbol Gene ID Gene Info
DMC1
ENSG00000100206.5 DNA meiotic recombinase 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
DMC1hg19_v2_chr22_-_38966123_38966163-0.613.9e-01Click!

Activity profile of DMC1 motif

Sorted Z-values of DMC1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_42875115 0.21 ENST00000591137.1
CTC-296K1.4
CTC-296K1.4
chr12_-_120805872 0.18 ENST00000546985.1
MSI1
musashi RNA-binding protein 1
chr17_+_57297807 0.16 ENST00000284116.4
ENST00000581140.1
ENST00000581276.1
GDPD1
glycerophosphodiester phosphodiesterase domain containing 1
chr21_-_35281399 0.15 ENST00000418933.1
ATP5O
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
chr5_-_66942617 0.14 ENST00000507298.1
RP11-83M16.5
RP11-83M16.5
chr2_-_31637560 0.13 ENST00000379416.3
XDH
xanthine dehydrogenase
chr11_-_73720276 0.13 ENST00000348534.4
UCP3
uncoupling protein 3 (mitochondrial, proton carrier)
chr3_-_156840776 0.12 ENST00000471357.1
LINC00880
long intergenic non-protein coding RNA 880
chr12_-_109025849 0.11 ENST00000228463.6
SELPLG
selectin P ligand
chr3_+_9944303 0.10 ENST00000421412.1
ENST00000295980.3
IL17RE
interleukin 17 receptor E
chr3_+_9944492 0.10 ENST00000383814.3
ENST00000454190.2
ENST00000454992.1
IL17RE
interleukin 17 receptor E
chr11_-_73720122 0.09 ENST00000426995.2
UCP3
uncoupling protein 3 (mitochondrial, proton carrier)
chr17_+_77018896 0.08 ENST00000578229.1
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr19_-_3600549 0.08 ENST00000589966.1
TBXA2R
thromboxane A2 receptor
chr2_-_197675000 0.07 ENST00000342506.2
C2orf66
chromosome 2 open reading frame 66
chr8_+_67104940 0.07 ENST00000517689.1
LINC00967
long intergenic non-protein coding RNA 967
chr11_-_85779971 0.06 ENST00000393346.3
PICALM
phosphatidylinositol binding clathrin assembly protein
chr2_+_187454749 0.06 ENST00000261023.3
ENST00000374907.3
ITGAV
integrin, alpha V
chr21_-_46348626 0.06 ENST00000517563.1
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr6_+_88054530 0.06 ENST00000388923.4
C6orf163
chromosome 6 open reading frame 163
chr10_+_74870206 0.06 ENST00000357321.4
ENST00000349051.5
NUDT13
nudix (nucleoside diphosphate linked moiety X)-type motif 13
chr17_+_38333263 0.06 ENST00000456989.2
ENST00000543876.1
ENST00000544503.1
ENST00000264644.6
ENST00000538884.1
RAPGEFL1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr11_-_85780086 0.05 ENST00000532317.1
ENST00000528256.1
ENST00000526033.1
PICALM
phosphatidylinositol binding clathrin assembly protein
chr14_-_21492113 0.05 ENST00000554094.1
NDRG2
NDRG family member 2
chr2_+_219246746 0.05 ENST00000233202.6
SLC11A1
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
chr1_-_19811132 0.05 ENST00000433834.1
CAPZB
capping protein (actin filament) muscle Z-line, beta
chr21_-_46348694 0.05 ENST00000355153.4
ENST00000397850.2
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr2_+_48667983 0.05 ENST00000449090.2
PPP1R21
protein phosphatase 1, regulatory subunit 21
chr15_-_49103235 0.05 ENST00000380950.2
CEP152
centrosomal protein 152kDa
chr10_+_62538248 0.05 ENST00000448257.2
CDK1
cyclin-dependent kinase 1
chr2_+_61244697 0.04 ENST00000401576.1
ENST00000295030.5
ENST00000414712.2
PEX13
peroxisomal biogenesis factor 13
chr14_-_21491477 0.04 ENST00000298684.5
ENST00000557169.1
ENST00000553563.1
NDRG2
NDRG family member 2
chr10_+_69865866 0.04 ENST00000354393.2
MYPN
myopalladin
chr7_-_15601595 0.04 ENST00000342526.3
AGMO
alkylglycerol monooxygenase
chr8_+_145438870 0.04 ENST00000527931.1
FAM203B
family with sequence similarity 203, member B
chr10_-_135187193 0.04 ENST00000368547.3
ECHS1
enoyl CoA hydratase, short chain, 1, mitochondrial
chr2_+_136343904 0.04 ENST00000436436.1
R3HDM1
R3H domain containing 1
chr2_+_233497931 0.03 ENST00000264059.3
EFHD1
EF-hand domain family, member D1
chr20_+_2796948 0.03 ENST00000361033.1
ENST00000380585.1
TMEM239
transmembrane protein 239
chr10_+_74870253 0.03 ENST00000544879.1
ENST00000537969.1
ENST00000372997.3
NUDT13
nudix (nucleoside diphosphate linked moiety X)-type motif 13
chr2_+_48667898 0.03 ENST00000281394.4
ENST00000294952.8
PPP1R21
protein phosphatase 1, regulatory subunit 21
chr16_+_2255710 0.03 ENST00000397124.1
ENST00000565250.1
MLST8
MTOR associated protein, LST8 homolog (S. cerevisiae)
chr4_-_76944621 0.03 ENST00000306602.1
CXCL10
chemokine (C-X-C motif) ligand 10
chr11_+_101785727 0.03 ENST00000263468.8
KIAA1377
KIAA1377
chr6_-_31670723 0.02 ENST00000440843.2
ENST00000375842.4
ABHD16A
abhydrolase domain containing 16A
chr10_+_17851362 0.02 ENST00000331429.2
ENST00000457317.1
MRC1L1
cDNA FLJ56855, highly similar to Macrophage mannose receptor 1
chr2_-_21022818 0.02 ENST00000440866.2
ENST00000541941.1
ENST00000402479.2
ENST00000435420.2
ENST00000432947.1
ENST00000403006.2
ENST00000419825.2
ENST00000381090.3
ENST00000237822.3
ENST00000412261.1
C2orf43
chromosome 2 open reading frame 43
chr6_-_150067696 0.02 ENST00000340413.2
ENST00000367403.3
NUP43
nucleoporin 43kDa
chr3_-_99569821 0.02 ENST00000487087.1
FILIP1L
filamin A interacting protein 1-like
chr12_-_71031185 0.01 ENST00000548122.1
ENST00000551525.1
ENST00000550358.1
PTPRB
protein tyrosine phosphatase, receptor type, B
chr1_+_12290121 0.01 ENST00000358136.3
ENST00000356315.4
VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr12_-_8803128 0.01 ENST00000543467.1
MFAP5
microfibrillar associated protein 5
chr14_-_68157084 0.01 ENST00000557564.1
RP11-1012A1.4
RP11-1012A1.4
chr22_+_21133469 0.01 ENST00000406799.1
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr16_-_85969774 0.01 ENST00000598933.1
RP11-542M13.3
RP11-542M13.3
chr10_-_74856608 0.01 ENST00000307116.2
ENST00000373008.2
ENST00000412021.2
ENST00000394890.2
ENST00000263556.3
ENST00000440381.1
P4HA1
prolyl 4-hydroxylase, alpha polypeptide I
chr14_+_74318513 0.01 ENST00000555228.1
ENST00000555661.1
PTGR2
prostaglandin reductase 2
chr14_+_74318611 0.01 ENST00000555976.1
ENST00000267568.4
PTGR2
prostaglandin reductase 2
chr17_-_60142609 0.01 ENST00000397786.2
MED13
mediator complex subunit 13
chr7_+_107332334 0.01 ENST00000541474.1
ENST00000544569.1
SLC26A4
solute carrier family 26 (anion exchanger), member 4
chr12_-_71031220 0.01 ENST00000334414.6
PTPRB
protein tyrosine phosphatase, receptor type, B
chr14_-_21492251 0.01 ENST00000554398.1
NDRG2
NDRG family member 2
chr10_+_11047259 0.01 ENST00000379261.4
ENST00000416382.2
CELF2
CUGBP, Elav-like family member 2
chr7_+_6793740 0.01 ENST00000403107.1
ENST00000404077.1
ENST00000435395.1
ENST00000418406.1
RSPH10B2
radial spoke head 10 homolog B2 (Chlamydomonas)
chr1_-_47131521 0.01 ENST00000542495.1
ENST00000532925.1
ATPAF1
ATP synthase mitochondrial F1 complex assembly factor 1
chr12_-_50677255 0.01 ENST00000551691.1
ENST00000394943.3
ENST00000341247.4
LIMA1
LIM domain and actin binding 1
chr2_+_201173667 0.01 ENST00000409755.3
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr2_-_75788038 0.00 ENST00000393913.3
ENST00000410113.1
EVA1A
eva-1 homolog A (C. elegans)
chr2_-_85641162 0.00 ENST00000447219.2
ENST00000409670.1
ENST00000409724.1
CAPG
capping protein (actin filament), gelsolin-like
chr2_+_171640291 0.00 ENST00000409885.1
ERICH2
glutamate-rich 2
chr7_+_142919130 0.00 ENST00000408947.3
TAS2R40
taste receptor, type 2, member 40
chr17_+_74075263 0.00 ENST00000334586.5
ENST00000392503.2
ZACN
zinc activated ligand-gated ion channel
chr6_-_150067632 0.00 ENST00000460354.2
ENST00000367404.4
ENST00000543637.1
NUP43
nucleoporin 43kDa
chr7_-_6010263 0.00 ENST00000455618.2
ENST00000405415.1
ENST00000404406.1
ENST00000542644.1
RSPH10B
radial spoke head 10 homolog B (Chlamydomonas)
chr8_-_101734907 0.00 ENST00000318607.5
ENST00000521865.1
ENST00000520804.1
ENST00000522720.1
ENST00000521067.1
PABPC1
poly(A) binding protein, cytoplasmic 1

Network of associatons between targets according to the STRING database.

First level regulatory network of DMC1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.0 0.1 GO:0046110 xanthine metabolic process(GO:0046110)
0.0 0.1 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.0 0.2 GO:0097398 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.1 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.1 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.0 GO:0060151 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.0 0.2 GO:1990845 adaptive thermogenesis(GO:1990845)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0034685 integrin alphav-beta6 complex(GO:0034685) integrin alphav-beta8 complex(GO:0034686)
0.0 0.1 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.1 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.1 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.0 0.0 GO:0051139 metal ion:proton antiporter activity(GO:0051139)
0.0 0.1 GO:0030369 ICAM-3 receptor activity(GO:0030369)