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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)
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Results for DBP
Z-value: 0.89
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Transcription factors associated with DBP
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| DBP | hg19_v2_chr19_-_49140692_49140709 | 0.83 | 1.7e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr14_-_37051798 Show fit | 0.81 |
ENST00000258829.5
|
NK2 homeobox 8 |
|
| chr16_+_30675654 Show fit | 0.60 |
ENST00000287468.5
ENST00000395073.2 |
fibrosin |
|
| chr7_+_13141010 Show fit | 0.58 |
ENST00000443947.1
|
AC011288.2 |
|
| chr5_-_27038683 Show fit | 0.53 |
ENST00000511822.1
ENST00000231021.4 |
cadherin 9, type 2 (T1-cadherin) |
|
| chr11_+_394145 Show fit | 0.49 |
ENST00000528036.1
|
plakophilin 3 |
|
| chr19_-_56047661 Show fit | 0.45 |
ENST00000344158.3
|
SH3 domain binding kinase family, member 2 |
|
| chr16_+_2059872 Show fit | 0.43 |
ENST00000567649.1
|
neuropeptide W |
|
| chr6_-_33168391 Show fit | 0.41 |
ENST00000374685.4
ENST00000413614.2 ENST00000374680.3 |
retinoid X receptor, beta |
|
| chr19_-_41220957 Show fit | 0.39 |
ENST00000596357.1
ENST00000243583.6 ENST00000600080.1 ENST00000595254.1 ENST00000601967.1 |
aarF domain containing kinase 4 |
|
| chr6_+_26045603 Show fit | 0.39 |
ENST00000540144.1
|
histone cluster 1, H3c |
Network of associatons between targets according to the STRING database.
First level regulatory network of DBP
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.7 | GO:0002159 | desmosome assembly(GO:0002159) |
| 0.1 | 0.5 | GO:0072709 | cellular response to sorbitol(GO:0072709) |
| 0.0 | 0.4 | GO:1902961 | positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247) |
| 0.1 | 0.3 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
| 0.1 | 0.3 | GO:0038018 | Wnt receptor catabolic process(GO:0038018) |
| 0.1 | 0.3 | GO:1901545 | cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545) |
| 0.1 | 0.3 | GO:0010966 | regulation of phosphate transport(GO:0010966) |
| 0.0 | 0.3 | GO:0006420 | arginyl-tRNA aminoacylation(GO:0006420) |
| 0.0 | 0.3 | GO:0021546 | rhombomere development(GO:0021546) |
| 0.0 | 0.3 | GO:0061146 | Peyer's patch morphogenesis(GO:0061146) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.7 | GO:0030057 | desmosome(GO:0030057) |
| 0.0 | 0.4 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.1 | 0.3 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 0.0 | 0.3 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
| 0.0 | 0.2 | GO:0043564 | Ku70:Ku80 complex(GO:0043564) |
| 0.0 | 0.2 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 0.0 | 0.2 | GO:0045254 | pyruvate dehydrogenase complex(GO:0045254) |
| 0.0 | 0.2 | GO:0071144 | SMAD2-SMAD3 protein complex(GO:0071144) |
| 0.0 | 0.1 | GO:0009368 | endopeptidase Clp complex(GO:0009368) |
| 0.0 | 0.1 | GO:0044753 | amphisome(GO:0044753) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.6 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.0 | 0.5 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
| 0.1 | 0.4 | GO:0004886 | 9-cis retinoic acid receptor activity(GO:0004886) |
| 0.0 | 0.4 | GO:0004969 | histamine receptor activity(GO:0004969) |
| 0.0 | 0.4 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 0.0 | 0.3 | GO:0004814 | arginine-tRNA ligase activity(GO:0004814) |
| 0.0 | 0.3 | GO:0050119 | N-acetylglucosamine deacetylase activity(GO:0050119) |
| 0.0 | 0.3 | GO:0019855 | calcium channel inhibitor activity(GO:0019855) |
| 0.0 | 0.2 | GO:0035575 | histone demethylase activity (H4-K20 specific)(GO:0035575) |
| 0.0 | 0.2 | GO:0034604 | pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.5 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.7 | REACTOME RNA POL I PROMOTER OPENING | Genes involved in RNA Polymerase I Promoter Opening |
| 0.0 | 0.6 | REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION | Genes involved in activated TAK1 mediates p38 MAPK activation |
| 0.0 | 0.4 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.0 | 0.2 | REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |