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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)
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Results for CXXC1
Z-value: 1.87
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Transcription factors associated with CXXC1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| CXXC1 | hg19_v2_chr18_-_47814032_47814079 | -0.87 | 1.3e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr2_+_183989157 Show fit | 0.86 |
ENST00000541912.1
|
nucleoporin 35kDa |
|
| chr19_-_39735646 Show fit | 0.71 |
ENST00000413851.2
|
interferon, lambda 3 |
|
| chr17_+_29421987 Show fit | 0.70 |
ENST00000431387.4
|
neurofibromin 1 |
|
| chr19_+_39759154 Show fit | 0.69 |
ENST00000331982.5
|
interferon, lambda 2 |
|
| chr1_-_67390474 Show fit | 0.68 |
ENST00000371023.3
ENST00000371022.3 ENST00000371026.3 ENST00000431318.1 |
WD repeat domain 78 |
|
| chr1_+_40723779 Show fit | 0.67 |
ENST00000372759.3
|
zinc metallopeptidase STE24 |
|
| chr5_+_95998746 Show fit | 0.66 |
ENST00000508608.1
|
calpastatin |
|
| chr19_-_51289374 Show fit | 0.61 |
ENST00000563228.1
|
CTD-2568A17.1 |
|
| chr14_-_81687197 Show fit | 0.58 |
ENST00000553612.1
|
general transcription factor IIA, 1, 19/37kDa |
|
| chr11_+_32605350 Show fit | 0.55 |
ENST00000531120.1
ENST00000524896.1 ENST00000323213.5 |
eukaryotic translation initiation factor 3, subunit M |
Network of associatons between targets according to the STRING database.
First level regulatory network of CXXC1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.1 | GO:0006409 | tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431) |
| 0.0 | 1.6 | GO:0042795 | snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795) |
| 0.0 | 1.5 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.0 | 1.3 | GO:0006363 | termination of RNA polymerase I transcription(GO:0006363) |
| 0.0 | 1.3 | GO:0070126 | mitochondrial translational termination(GO:0070126) |
| 0.1 | 1.2 | GO:0071763 | nuclear membrane organization(GO:0071763) |
| 0.0 | 1.2 | GO:0061014 | positive regulation of mRNA catabolic process(GO:0061014) |
| 0.4 | 1.1 | GO:0061534 | gamma-aminobutyric acid secretion, neurotransmission(GO:0061534) |
| 0.0 | 1.1 | GO:0003341 | cilium movement(GO:0003341) |
| 0.0 | 1.0 | GO:0006968 | cellular defense response(GO:0006968) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.8 | GO:0016580 | Sin3 complex(GO:0016580) |
| 0.0 | 1.6 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 0.0 | 1.4 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.1 | 1.3 | GO:0005652 | nuclear lamina(GO:0005652) |
| 0.0 | 1.3 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.1 | 1.1 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 0.0 | 1.1 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.1 | 1.0 | GO:0032039 | integrator complex(GO:0032039) |
| 0.1 | 1.0 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 0.1 | 0.9 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.7 | GO:0047485 | protein N-terminus binding(GO:0047485) |
| 0.0 | 1.5 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
| 0.0 | 1.4 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 0.0 | 1.4 | GO:0003730 | mRNA 3'-UTR binding(GO:0003730) |
| 0.0 | 1.3 | GO:0070717 | poly-purine tract binding(GO:0070717) |
| 0.0 | 1.3 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.0 | 1.3 | GO:0050681 | androgen receptor binding(GO:0050681) |
| 0.1 | 1.1 | GO:0008097 | 5S rRNA binding(GO:0008097) |
| 0.0 | 1.1 | GO:0043021 | ribonucleoprotein complex binding(GO:0043021) |
| 0.1 | 1.0 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.8 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.0 | 1.4 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.0 | 1.1 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.0 | 1.1 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.0 | 1.1 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.0 | 1.1 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.0 | 1.0 | PID BMP PATHWAY | BMP receptor signaling |
| 0.0 | 0.7 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.0 | 0.6 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.0 | 0.5 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.6 | REACTOME TRANSLATION | Genes involved in Translation |
| 0.0 | 1.9 | REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS | Genes involved in Transport of Ribonucleoproteins into the Host Nucleus |
| 0.0 | 1.5 | REACTOME RNA POL II PRE TRANSCRIPTION EVENTS | Genes involved in RNA Polymerase II Pre-transcription Events |
| 0.0 | 1.3 | REACTOME RNA POL I TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase I Transcription Termination |
| 0.0 | 1.2 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.0 | 1.1 | REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS | Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components |
| 0.0 | 1.1 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.0 | 1.0 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.0 | 1.0 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.0 | 0.9 | REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter |