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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)
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Results for CUX2
Z-value: 1.37
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Transcription factors associated with CUX2
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr17_+_61151306 Show fit | 1.62 |
ENST00000580068.1
ENST00000580466.1 |
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
|
| chr17_+_34171081 Show fit | 1.09 |
ENST00000585577.1
|
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
|
| chr19_-_58864848 Show fit | 1.09 |
ENST00000263100.3
|
alpha-1-B glycoprotein |
|
| chr19_+_507299 Show fit | 1.03 |
ENST00000359315.5
|
tubulin polyglutamylase complex subunit 1 |
|
| chr14_-_81425828 Show fit | 0.93 |
ENST00000555529.1
ENST00000556042.1 ENST00000556981.1 |
centrosomal protein 128kDa |
|
| chr8_-_145754428 Show fit | 0.86 |
ENST00000527462.1
ENST00000313465.5 ENST00000524821.1 |
chromosome 8 open reading frame 82 |
|
| chrY_+_15418467 Show fit | 0.85 |
ENST00000595988.1
|
Uncharacterized protein |
|
| chr17_+_67498396 Show fit | 0.72 |
ENST00000588110.1
|
mitogen-activated protein kinase kinase 6 |
|
| chr12_+_7052974 Show fit | 0.72 |
ENST00000544681.1
ENST00000537087.1 |
chromosome 12 open reading frame 57 |
|
| chr6_-_27799305 Show fit | 0.71 |
ENST00000357549.2
|
histone cluster 1, H4k |
Network of associatons between targets according to the STRING database.
First level regulatory network of CUX2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.1 | GO:0072709 | cellular response to sorbitol(GO:0072709) |
| 0.1 | 0.8 | GO:0007288 | sperm axoneme assembly(GO:0007288) |
| 0.2 | 0.7 | GO:0048597 | B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597) |
| 0.0 | 0.6 | GO:0032494 | response to peptidoglycan(GO:0032494) |
| 0.0 | 0.6 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
| 0.0 | 0.6 | GO:0032008 | positive regulation of TOR signaling(GO:0032008) |
| 0.1 | 0.5 | GO:0046092 | deoxycytidine metabolic process(GO:0046092) |
| 0.1 | 0.5 | GO:0061084 | regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084) |
| 0.0 | 0.5 | GO:0006068 | ethanol catabolic process(GO:0006068) |
| 0.0 | 0.5 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.8 | GO:0000243 | commitment complex(GO:0000243) |
| 0.1 | 0.7 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.0 | 0.7 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.1 | 0.6 | GO:0043541 | UDP-N-acetylglucosamine transferase complex(GO:0043541) |
| 0.0 | 0.4 | GO:0045254 | pyruvate dehydrogenase complex(GO:0045254) |
| 0.1 | 0.3 | GO:0032002 | interleukin-28 receptor complex(GO:0032002) |
| 0.1 | 0.3 | GO:0072536 | interleukin-23 receptor complex(GO:0072536) |
| 0.1 | 0.3 | GO:0001674 | female germ cell nucleus(GO:0001674) |
| 0.0 | 0.3 | GO:0061574 | ASAP complex(GO:0061574) |
| 0.0 | 0.3 | GO:0097524 | sperm plasma membrane(GO:0097524) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.1 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
| 0.1 | 1.0 | GO:0070740 | tubulin-glutamic acid ligase activity(GO:0070740) |
| 0.0 | 0.7 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.1 | 0.6 | GO:0050509 | N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509) |
| 0.1 | 0.5 | GO:0004137 | deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797) |
| 0.1 | 0.5 | GO:0047894 | flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294) |
| 0.0 | 0.5 | GO:1990446 | U1 snRNP binding(GO:1990446) |
| 0.0 | 0.5 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
| 0.0 | 0.5 | GO:0051400 | BH domain binding(GO:0051400) |
| 0.0 | 0.5 | GO:0035198 | miRNA binding(GO:0035198) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.1 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.0 | 1.1 | ST PHOSPHOINOSITIDE 3 KINASE PATHWAY | PI3K Pathway |
| 0.0 | 0.9 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 0.7 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.1 | REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION | Genes involved in activated TAK1 mediates p38 MAPK activation |
| 0.0 | 1.1 | REACTOME PACKAGING OF TELOMERE ENDS | Genes involved in Packaging Of Telomere Ends |
| 0.0 | 0.9 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.0 | 0.7 | REACTOME INTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Intrinsic Pathway for Apoptosis |
| 0.0 | 0.5 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.0 | 0.5 | REACTOME REGULATION OF COMPLEMENT CASCADE | Genes involved in Regulation of Complement cascade |
| 0.0 | 0.5 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 0.0 | 0.5 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.0 | 0.4 | REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
| 0.0 | 0.4 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |