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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)
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Results for CTCF_CTCFL
Z-value: 2.48
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Transcription factors associated with CTCF_CTCFL
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| CTCFL | hg19_v2_chr20_-_56100155_56100163 | -0.88 | 1.2e-01 | Click! |
| CTCF | hg19_v2_chr16_+_67596310_67596353 | -0.42 | 5.8e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr4_+_76649753 Show fit | 4.04 |
ENST00000603759.1
|
USO1 vesicle transport factor |
|
| chr20_+_48807351 Show fit | 1.96 |
ENST00000303004.3
|
CCAAT/enhancer binding protein (C/EBP), beta |
|
| chr19_+_507299 Show fit | 1.78 |
ENST00000359315.5
|
tubulin polyglutamylase complex subunit 1 |
|
| chr19_+_38893809 Show fit | 1.75 |
ENST00000589408.1
|
family with sequence similarity 98, member C |
|
| chr2_+_130939827 Show fit | 1.74 |
ENST00000409255.1
ENST00000455239.1 |
mitotic spindle organizing protein 2B |
|
| chr11_-_61584233 Show fit | 1.66 |
ENST00000491310.1
|
fatty acid desaturase 1 |
|
| chr7_+_73082152 Show fit | 1.55 |
ENST00000324941.4
ENST00000451519.1 |
vacuolar protein sorting 37 homolog D (S. cerevisiae) |
|
| chr9_+_140317802 Show fit | 1.55 |
ENST00000341349.2
ENST00000392815.2 |
NADPH oxidase activator 1 |
|
| chr20_-_34542548 Show fit | 1.53 |
ENST00000305978.2
|
SCAN domain containing 1 |
|
| chr8_-_11873043 Show fit | 1.52 |
ENST00000527396.1
|
Protein LOC101060662 |
Network of associatons between targets according to the STRING database.
First level regulatory network of CTCF_CTCFL
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 3.9 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
| 1.0 | 3.1 | GO:0043181 | vacuolar sequestering(GO:0043181) |
| 0.2 | 2.3 | GO:0039536 | negative regulation of RIG-I signaling pathway(GO:0039536) |
| 0.0 | 2.1 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
| 0.1 | 2.0 | GO:1990440 | positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440) |
| 0.1 | 2.0 | GO:0043651 | linoleic acid metabolic process(GO:0043651) |
| 0.2 | 1.8 | GO:0007288 | sperm axoneme assembly(GO:0007288) |
| 0.1 | 1.8 | GO:0046339 | diacylglycerol metabolic process(GO:0046339) |
| 0.1 | 1.7 | GO:0039702 | viral budding via host ESCRT complex(GO:0039702) |
| 0.1 | 1.6 | GO:0030259 | lipid glycosylation(GO:0030259) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 5.3 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.1 | 4.0 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
| 0.3 | 3.7 | GO:0000931 | gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274) |
| 0.0 | 3.5 | GO:0035577 | azurophil granule membrane(GO:0035577) |
| 0.0 | 2.9 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.2 | 2.6 | GO:0072669 | tRNA-splicing ligase complex(GO:0072669) |
| 0.0 | 2.5 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.1 | 1.7 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.1 | 1.6 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 0.2 | 1.4 | GO:0045323 | interleukin-1 receptor complex(GO:0045323) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.9 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 1.0 | 3.1 | GO:0004574 | oligo-1,6-glucosidase activity(GO:0004574) |
| 0.0 | 2.9 | GO:0008565 | protein transporter activity(GO:0008565) |
| 0.1 | 1.9 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
| 0.2 | 1.8 | GO:0070740 | tubulin-glutamic acid ligase activity(GO:0070740) |
| 0.6 | 1.7 | GO:0045485 | omega-6 fatty acid desaturase activity(GO:0045485) |
| 0.3 | 1.6 | GO:0003947 | (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity(GO:0003947) |
| 0.1 | 1.6 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 0.5 | 1.5 | GO:0046964 | 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964) |
| 0.1 | 1.5 | GO:0036374 | glutathione hydrolase activity(GO:0036374) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.4 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.1 | 4.0 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.0 | 3.2 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.0 | 3.0 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.0 | 1.8 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 0.0 | 1.4 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.0 | 0.9 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.0 | 0.9 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.0 | 0.9 | ST B CELL ANTIGEN RECEPTOR | B Cell Antigen Receptor |
| 0.0 | 0.8 | PID P53 REGULATION PATHWAY | p53 pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.6 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.1 | 2.0 | REACTOME ALPHA LINOLENIC ACID ALA METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
| 0.0 | 1.7 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.1 | 1.5 | REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS | Genes involved in Membrane binding and targetting of GAG proteins |
| 0.1 | 1.4 | REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL | Genes involved in NF-kB is activated and signals survival |
| 0.0 | 1.4 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.0 | 1.3 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.0 | 1.2 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.1 | 1.1 | REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY | Genes involved in Adenylate cyclase activating pathway |
| 0.0 | 1.1 | REACTOME MITOCHONDRIAL TRNA AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |