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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)
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Results for CDC5L
Z-value: 0.73
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Transcription factors associated with CDC5L
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| CDC5L | hg19_v2_chr6_+_44355257_44355315 | 0.55 | 4.5e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chrX_-_11129229 Show fit | 0.44 |
ENST00000608176.1
ENST00000433747.2 ENST00000608576.1 ENST00000608916.1 |
RP11-120D5.1 |
|
| chr2_+_200472779 Show fit | 0.37 |
ENST00000427045.1
ENST00000419243.1 |
AC093590.1 |
|
| chr18_-_37380230 Show fit | 0.31 |
ENST00000591629.1
|
long intergenic non-protein coding RNA 669 |
|
| chr1_-_154178803 Show fit | 0.30 |
ENST00000368525.3
|
chromosome 1 open reading frame 189 |
|
| chr3_+_57882061 Show fit | 0.29 |
ENST00000461354.1
ENST00000466255.1 |
sarcolemma associated protein |
|
| chr14_+_104029362 Show fit | 0.29 |
ENST00000495778.1
|
apoptogenic 1, mitochondrial |
|
| chr21_+_35107346 Show fit | 0.28 |
ENST00000456489.1
|
intersectin 1 (SH3 domain protein) |
|
| chr6_+_76599809 Show fit | 0.27 |
ENST00000430435.1
|
myosin VI |
|
| chr8_+_52730143 Show fit | 0.27 |
ENST00000415643.1
|
Uncharacterized protein |
|
| chr2_-_203103185 Show fit | 0.24 |
ENST00000409205.1
|
small ubiquitin-like modifier 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of CDC5L
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.5 | GO:1903824 | regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824) |
| 0.1 | 0.4 | GO:1901896 | positive regulation of calcium-transporting ATPase activity(GO:1901896) |
| 0.0 | 0.4 | GO:1905150 | regulation of voltage-gated sodium channel activity(GO:1905150) |
| 0.0 | 0.4 | GO:0034393 | positive regulation of smooth muscle cell apoptotic process(GO:0034393) |
| 0.1 | 0.3 | GO:0008204 | ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204) |
| 0.1 | 0.3 | GO:1903613 | regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615) |
| 0.1 | 0.3 | GO:0051083 | 'de novo' cotranslational protein folding(GO:0051083) |
| 0.0 | 0.3 | GO:0097056 | selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056) |
| 0.1 | 0.2 | GO:1990519 | pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519) |
| 0.1 | 0.2 | GO:0035188 | blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.5 | GO:0030870 | Mre11 complex(GO:0030870) |
| 0.1 | 0.4 | GO:0031510 | SUMO activating enzyme complex(GO:0031510) |
| 0.0 | 0.3 | GO:0097025 | MPP7-DLG1-LIN7 complex(GO:0097025) |
| 0.0 | 0.3 | GO:0016461 | unconventional myosin complex(GO:0016461) |
| 0.0 | 0.2 | GO:0000836 | Hrd1p ubiquitin ligase complex(GO:0000836) |
| 0.0 | 0.1 | GO:0044279 | other organism cell membrane(GO:0044218) other organism membrane(GO:0044279) |
| 0.0 | 0.1 | GO:0005595 | collagen type XII trimer(GO:0005595) |
| 0.0 | 0.1 | GO:0005656 | nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387) |
| 0.0 | 0.1 | GO:0071006 | U2-type catalytic step 1 spliceosome(GO:0071006) |
| 0.0 | 0.1 | GO:0034669 | integrin alpha4-beta7 complex(GO:0034669) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.5 | GO:0003720 | telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964) |
| 0.0 | 0.4 | GO:0044388 | small protein activating enzyme binding(GO:0044388) |
| 0.1 | 0.3 | GO:0060001 | minus-end directed microfilament motor activity(GO:0060001) |
| 0.1 | 0.3 | GO:0051996 | farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996) |
| 0.0 | 0.3 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
| 0.1 | 0.2 | GO:0015218 | pyrimidine nucleotide transmembrane transporter activity(GO:0015218) |
| 0.0 | 0.2 | GO:0016531 | copper chaperone activity(GO:0016531) |
| 0.0 | 0.2 | GO:0015173 | aromatic amino acid transmembrane transporter activity(GO:0015173) |
| 0.0 | 0.2 | GO:0015111 | iodide transmembrane transporter activity(GO:0015111) |
| 0.0 | 0.2 | GO:0097016 | L27 domain binding(GO:0097016) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.0 | 0.2 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | REACTOME REGULATION OF IFNG SIGNALING | Genes involved in Regulation of IFNG signaling |
| 0.0 | 0.3 | REACTOME GAP JUNCTION DEGRADATION | Genes involved in Gap junction degradation |
| 0.0 | 0.2 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
| 0.0 | 0.2 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |