ISMARA results: BPTF

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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for BPTF

Z-value: 1.04

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Transcription factors associated with BPTF

Gene Symbol	Gene ID	Gene Info
BPTF Ensembl NCBI GeneCards UniProt	ENSG00000171634.12	bromodomain PHD finger transcription factor

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
BPTF	hg19_v2_chr17_+_65821780_65821826	0.44	5.6e-01	Click!

Activity profile of BPTF motif

Sorted Z-values of BPTF motif

Top targets:

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr17_-_15469590 Show fit	0.58	ENST00000312127.2	CDRT1 Ensembl NCBI GeneCards UniProt Show fit	CMT duplicated region transcript 1; Uncharacterized protein
chr10_-_10504285 Show fit	0.54	ENST00000602311.1	RP11-271F18.4 Ensembl NCBI GeneCards UniProt Show fit	RP11-271F18.4
chr16_+_85832146 Show fit	0.48	ENST00000565078.1	COX4I1 Ensembl NCBI GeneCards UniProt Show fit	cytochrome c oxidase subunit IV isoform 1
chr3_-_196987309 Show fit	0.47	ENST00000453607.1	DLG1 Ensembl NCBI GeneCards UniProt Show fit	discs, large homolog 1 (Drosophila)
chr14_+_104029362 Show fit	0.44	ENST00000495778.1	APOPT1 Ensembl NCBI GeneCards UniProt Show fit	apoptogenic 1, mitochondrial
chr3_-_4927447 Show fit	0.42	ENST00000449914.1	AC018816.3 Ensembl NCBI GeneCards UniProt Show fit	Uncharacterized protein
chr18_+_68002675 Show fit	0.40	ENST00000584919.1	RP11-41O4.1 Ensembl NCBI GeneCards UniProt Show fit	Uncharacterized protein
chr6_-_31651817 Show fit	0.39	ENST00000375863.3 ENST00000375860.2	LY6G5C Ensembl NCBI GeneCards UniProt Show fit	lymphocyte antigen 6 complex, locus G5C
chr17_+_9479944 Show fit	0.38	ENST00000396219.3 ENST00000352665.5	WDR16 Ensembl NCBI GeneCards UniProt Show fit	WD repeat domain 16
chr8_+_38261880 Show fit	0.38	ENST00000527175.1	LETM2 Ensembl NCBI GeneCards UniProt Show fit	leucine zipper-EF-hand containing transmembrane protein 2

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of BPTF

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.8	GO:0000027	ribosomal large subunit assembly(GO:0000027)
0.1	0.7	GO:1903760	regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.1	0.6	GO:0034393	positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.1	0.5	GO:1902255	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.0	0.5	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	0.4	GO:1905150	regulation of voltage-gated sodium channel activity(GO:1905150)
0.0	0.4	GO:0002318	myeloid progenitor cell differentiation(GO:0002318)
0.0	0.4	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.4	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.4	GO:0043586	tongue development(GO:0043586)

Showing 1 to 10 of 261 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.7	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	0.7	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.1	0.4	GO:0005854	nascent polypeptide-associated complex(GO:0005854)
0.0	0.4	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.4	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.4	GO:0000314	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	0.4	GO:0032040	small-subunit processome(GO:0032040)
0.0	0.4	GO:0043189	NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1	0.3	GO:0020003	symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.1	0.3	GO:0097233	lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)

Showing 1 to 10 of 88 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.7	GO:0097016	L27 domain binding(GO:0097016)
0.0	0.5	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.0	0.5	GO:0016505	peptidase activator activity involved in apoptotic process(GO:0016505)
0.0	0.5	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.0	0.4	GO:1990948	ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0	0.4	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0	0.4	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1	0.3	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.1	0.3	GO:0060001	minus-end directed microfilament motor activity(GO:0060001)
0.1	0.3	GO:0004139	deoxyribose-phosphate aldolase activity(GO:0004139)

Showing 1 to 10 of 155 entries

Gene overrepresentation in C2:CP category:

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Total log-likelihood	Term	Description
0.5	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.0	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.

Showing 1 to 4 of 4 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Total log-likelihood	Term	Description
2.3	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.8	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.8	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.5	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.5	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.4	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.4	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.4	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.4	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.4	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport

Showing 1 to 10 of 25 entries

Results for BPTF

Z-value: 1.04

Motif logo

Transcription factors associated with BPTF

Activity-expression correlation:

Activity profile of BPTF motif

Sorted Z-values of BPTF motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of BPTF

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: