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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)
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Results for BHLHE40
Z-value: 1.14
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Transcription factors associated with BHLHE40
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| BHLHE40 | hg19_v2_chr3_+_5020801_5020952 | 0.50 | 5.0e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr8_-_99129338 Show fit | 0.51 |
ENST00000520507.1
|
heat-responsive protein 12 |
|
| chr1_-_43638168 Show fit | 0.50 |
ENST00000431635.2
|
EBNA1 binding protein 2 |
|
| chrX_-_55187531 Show fit | 0.47 |
ENST00000489298.1
ENST00000477847.2 |
family with sequence similarity 104, member B |
|
| chr21_+_27107672 Show fit | 0.42 |
ENST00000400075.3
|
GA binding protein transcription factor, alpha subunit 60kDa |
|
| chr8_-_99129384 Show fit | 0.41 |
ENST00000521560.1
ENST00000254878.3 |
heat-responsive protein 12 |
|
| chr21_-_27107344 Show fit | 0.40 |
ENST00000457143.2
|
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 |
|
| chr12_+_93861282 Show fit | 0.39 |
ENST00000552217.1
ENST00000393128.4 ENST00000547098.1 |
mitochondrial ribosomal protein L42 |
|
| chr1_-_43637915 Show fit | 0.39 |
ENST00000236051.2
|
EBNA1 binding protein 2 |
|
| chr15_+_77713299 Show fit | 0.38 |
ENST00000559099.1
|
high mobility group 20A |
|
| chr5_+_89770664 Show fit | 0.36 |
ENST00000503973.1
ENST00000399107.1 |
polymerase (RNA) III (DNA directed) polypeptide G (32kD) |
Network of associatons between targets according to the STRING database.
First level regulatory network of BHLHE40
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.1 | GO:0030490 | maturation of SSU-rRNA(GO:0030490) |
| 0.1 | 0.8 | GO:0006189 | 'de novo' IMP biosynthetic process(GO:0006189) |
| 0.2 | 0.7 | GO:0006422 | aspartyl-tRNA aminoacylation(GO:0006422) |
| 0.0 | 0.7 | GO:0042776 | mitochondrial ATP synthesis coupled proton transport(GO:0042776) |
| 0.2 | 0.5 | GO:0046586 | regulation of calcium-dependent cell-cell adhesion(GO:0046586) |
| 0.1 | 0.5 | GO:0090156 | cellular sphingolipid homeostasis(GO:0090156) |
| 0.0 | 0.5 | GO:0006359 | regulation of transcription from RNA polymerase III promoter(GO:0006359) |
| 0.1 | 0.4 | GO:0045653 | negative regulation of megakaryocyte differentiation(GO:0045653) |
| 0.0 | 0.4 | GO:0051026 | chiasma assembly(GO:0051026) |
| 0.1 | 0.3 | GO:0009386 | translational attenuation(GO:0009386) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.9 | GO:0005763 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 0.0 | 0.8 | GO:0032040 | small-subunit processome(GO:0032040) |
| 0.0 | 0.7 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
| 0.0 | 0.7 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 0.0 | 0.7 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.0 | 0.6 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 0.1 | 0.5 | GO:0035339 | SPOTS complex(GO:0035339) |
| 0.1 | 0.4 | GO:0005713 | recombination nodule(GO:0005713) |
| 0.1 | 0.3 | GO:0070044 | synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044) |
| 0.0 | 0.3 | GO:0030891 | VCB complex(GO:0030891) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.8 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
| 0.1 | 0.7 | GO:0004815 | aspartate-tRNA ligase activity(GO:0004815) |
| 0.0 | 0.6 | GO:0030983 | mismatched DNA binding(GO:0030983) |
| 0.1 | 0.5 | GO:1990050 | phosphatidic acid transporter activity(GO:1990050) |
| 0.0 | 0.5 | GO:0005527 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.1 | 0.4 | GO:0034511 | U3 snoRNA binding(GO:0034511) |
| 0.0 | 0.4 | GO:0005412 | glucose:sodium symporter activity(GO:0005412) |
| 0.0 | 0.3 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
| 0.0 | 0.3 | GO:0008607 | phosphorylase kinase regulator activity(GO:0008607) |
| 0.0 | 0.3 | GO:0030169 | low-density lipoprotein particle binding(GO:0030169) |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.8 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.0 | 0.7 | REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
| 0.0 | 0.7 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 0.0 | 0.6 | REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Norepinephrine Neurotransmitter Release Cycle |
| 0.0 | 0.3 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.0 | 0.3 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.0 | 0.3 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.0 | 0.2 | REACTOME ACYL CHAIN REMODELLING OF PS | Genes involved in Acyl chain remodelling of PS |
| 0.0 | 0.2 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |