ISMARA results: BARHL1

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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for BARHL1

Z-value: 3.66

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Transcription factors associated with BARHL1

Gene Symbol	Gene ID	Gene Info
BARHL1 Ensembl NCBI GeneCards UniProt	ENSG00000125492.5	BarH like homeobox 1

Activity profile of BARHL1 motif

Sorted Z-values of BARHL1 motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr10_+_91061712 Show fit	1.65	ENST00000371826.3	IFIT2 Ensembl NCBI GeneCards UniProt Show fit	interferon-induced protein with tetratricopeptide repeats 2
chr9_+_78505581 Show fit	1.62	ENST00000376767.3 ENST00000376752.4	PCSK5 Ensembl NCBI GeneCards UniProt Show fit	proprotein convertase subtilisin/kexin type 5
chr19_+_39759154 Show fit	1.48	ENST00000331982.5	IFNL2 Ensembl NCBI GeneCards UniProt Show fit	interferon, lambda 2
chr14_-_88200641 Show fit	1.43	ENST00000556168.1	RP11-1152H15.1 Ensembl NCBI GeneCards UniProt Show fit	RP11-1152H15.1
chr3_+_182971335 Show fit	1.42	ENST00000464191.1	B3GNT5 Ensembl NCBI GeneCards UniProt Show fit	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr7_-_112635675 Show fit	1.33	ENST00000447785.1 ENST00000451962.1	AC018464.3 Ensembl NCBI GeneCards UniProt Show fit	AC018464.3
chr4_+_108815402 Show fit	1.32	ENST00000503385.1	SGMS2 Ensembl NCBI GeneCards UniProt Show fit	sphingomyelin synthase 2
chr5_+_169011033 Show fit	1.32	ENST00000513795.1	SPDL1 Ensembl NCBI GeneCards UniProt Show fit	spindle apparatus coiled-coil protein 1
chrX_+_106045891 Show fit	1.29	ENST00000357242.5 ENST00000310452.2 ENST00000481617.2 ENST00000276175.3	TBC1D8B Ensembl NCBI GeneCards UniProt Show fit	TBC1 domain family, member 8B (with GRAM domain)
chr12_+_56435637 Show fit	1.26	ENST00000356464.5 ENST00000552361.1	RPS26 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S26

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of BARHL1

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.3	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	2.2	GO:0033119	negative regulation of RNA splicing(GO:0033119)
0.0	2.2	GO:0002223	innate immune response activating cell surface receptor signaling pathway(GO:0002220) stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.2	2.1	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.1	2.1	GO:0000492	box C/D snoRNP assembly(GO:0000492)
0.1	2.1	GO:0071985	multivesicular body sorting pathway(GO:0071985)
0.7	2.0	GO:0071449	cellular response to lipid hydroperoxide(GO:0071449)
0.3	2.0	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0	2.0	GO:0030488	tRNA methylation(GO:0030488)
0.3	1.9	GO:0001999	renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure(GO:0001999) renin secretion into blood stream(GO:0002001)

Showing 1 to 10 of 684 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	5.0	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.0	3.4	GO:0005884	actin filament(GO:0005884)
0.2	3.0	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.2	2.9	GO:0070938	contractile ring(GO:0070938)
0.0	2.5	GO:0005814	centriole(GO:0005814)
0.2	2.3	GO:0071014	post-mRNA release spliceosomal complex(GO:0071014)
0.1	2.2	GO:0071438	invadopodium membrane(GO:0071438)
0.1	2.2	GO:0071437	invadopodium(GO:0071437)
0.0	2.2	GO:0005871	kinesin complex(GO:0005871)
0.2	2.1	GO:0070761	pre-snoRNP complex(GO:0070761)

Showing 1 to 10 of 284 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	4.2	GO:0016859	cis-trans isomerase activity(GO:0016859)
0.1	3.8	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1	3.3	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.4	2.8	GO:0044547	DNA topoisomerase binding(GO:0044547)
0.0	2.7	GO:0035254	glutamate receptor binding(GO:0035254)
0.0	2.6	GO:0003729	mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1	2.4	GO:0070717	poly-purine tract binding(GO:0070717)
0.0	2.4	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.5	2.3	GO:0047256	beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.2	2.1	GO:0008312	7S RNA binding(GO:0008312)

Showing 1 to 10 of 440 entries

Gene overrepresentation in C2:CP category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.7	PID BARD1 PATHWAY	BARD1 signaling events
0.0	3.6	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	3.1	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	2.5	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	2.4	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	2.3	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.1	1.9	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	1.9	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	1.7	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	1.6	PID RAC1 REG PATHWAY	Regulation of RAC1 activity

Showing 1 to 10 of 76 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	4.1	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	3.4	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	2.9	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.1	2.7	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	2.7	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	2.7	REACTOME TRANSLATION	Genes involved in Translation
0.0	2.4	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.1	2.2	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1	1.9	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1	1.8	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation

Showing 1 to 10 of 119 entries

Results for BARHL1

Z-value: 3.66

Motif logo

Transcription factors associated with BARHL1

Activity profile of BARHL1 motif

Sorted Z-values of BARHL1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of BARHL1

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: