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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)
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Results for ATF6
Z-value: 1.09
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Transcription factors associated with ATF6
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ATF6 | hg19_v2_chr1_+_161736072_161736093 | 0.73 | 2.7e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr12_+_147052 Show fit | 0.77 |
ENST00000594563.1
|
Uncharacterized protein |
|
| chr2_-_98612379 Show fit | 0.59 |
ENST00000425805.2
|
transmembrane protein 131 |
|
| chr16_+_53164833 Show fit | 0.54 |
ENST00000564845.1
|
chromodomain helicase DNA binding protein 9 |
|
| chr12_+_1100423 Show fit | 0.45 |
ENST00000592048.1
|
ELKS/RAB6-interacting/CAST family member 1 |
|
| chr4_+_39640787 Show fit | 0.44 |
ENST00000532680.1
|
RP11-539G18.2 |
|
| chr13_+_36920569 Show fit | 0.43 |
ENST00000379848.2
|
SPG20 opposite strand |
|
| chr14_-_50087312 Show fit | 0.43 |
ENST00000298289.6
|
ribosomal protein L36a-like |
|
| chr4_+_39640754 Show fit | 0.43 |
ENST00000529094.1
ENST00000533736.1 |
RP11-539G18.2 |
|
| chr5_-_132299290 Show fit | 0.43 |
ENST00000378595.3
|
AF4/FMR2 family, member 4 |
|
| chr12_+_72148614 Show fit | 0.40 |
ENST00000261263.3
|
RAB21, member RAS oncogene family |
Network of associatons between targets according to the STRING database.
First level regulatory network of ATF6
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.0 | GO:0070911 | global genome nucleotide-excision repair(GO:0070911) |
| 0.0 | 0.9 | GO:0007252 | I-kappaB phosphorylation(GO:0007252) |
| 0.1 | 0.7 | GO:0032511 | late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511) |
| 0.0 | 0.7 | GO:0034384 | high-density lipoprotein particle clearance(GO:0034384) |
| 0.0 | 0.7 | GO:0048853 | forebrain morphogenesis(GO:0048853) |
| 0.0 | 0.7 | GO:0016254 | preassembly of GPI anchor in ER membrane(GO:0016254) |
| 0.1 | 0.6 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 0.0 | 0.6 | GO:0071786 | endoplasmic reticulum tubular network organization(GO:0071786) |
| 0.0 | 0.6 | GO:0030488 | tRNA methylation(GO:0030488) |
| 0.1 | 0.5 | GO:1903381 | neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0036483) regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903381) negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903382) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.9 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.0 | 0.9 | GO:0031597 | cytosolic proteasome complex(GO:0031597) |
| 0.0 | 0.7 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 0.0 | 0.7 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.1 | 0.6 | GO:0097452 | GAIT complex(GO:0097452) |
| 0.0 | 0.6 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 0.0 | 0.6 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.0 | 0.6 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
| 0.0 | 0.5 | GO:0097227 | sperm annulus(GO:0097227) |
| 0.1 | 0.4 | GO:0075341 | host cell PML body(GO:0075341) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.3 | GO:0019003 | GDP binding(GO:0019003) |
| 0.0 | 1.1 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
| 0.0 | 0.8 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.1 | 0.7 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
| 0.1 | 0.7 | GO:0031386 | protein tag(GO:0031386) |
| 0.0 | 0.7 | GO:0008143 | poly(A) binding(GO:0008143) |
| 0.0 | 0.6 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
| 0.1 | 0.5 | GO:0004741 | [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741) |
| 0.1 | 0.5 | GO:0070573 | metallodipeptidase activity(GO:0070573) |
| 0.0 | 0.5 | GO:0035242 | protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.0 | PID NFKAPPAB CANONICAL PATHWAY | Canonical NF-kappaB pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.8 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.0 | 0.7 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 0.0 | 0.6 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.0 | 0.5 | REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
| 0.0 | 0.5 | REACTOME RETROGRADE NEUROTROPHIN SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
| 0.0 | 0.4 | REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX | Genes involved in Association of licensing factors with the pre-replicative complex |
| 0.0 | 0.3 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.0 | 0.3 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 0.0 | 0.2 | REACTOME PYRUVATE METABOLISM | Genes involved in Pyruvate metabolism |
| 0.0 | 0.2 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |