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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for ATF6

Z-value: 1.09

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Transcription factors associated with ATF6

Gene Symbol Gene ID Gene Info
ENSG00000118217.5 activating transcription factor 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ATF6hg19_v2_chr1_+_161736072_1617360930.732.7e-01Click!

Activity profile of ATF6 motif

Sorted Z-values of ATF6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_147052 0.77 ENST00000594563.1
Uncharacterized protein
chr2_-_98612379 0.59 ENST00000425805.2
transmembrane protein 131
chr16_+_53164833 0.54 ENST00000564845.1
chromodomain helicase DNA binding protein 9
chr12_+_1100423 0.45 ENST00000592048.1
ELKS/RAB6-interacting/CAST family member 1
chr4_+_39640787 0.44 ENST00000532680.1
RP11-539G18.2
chr13_+_36920569 0.43 ENST00000379848.2
SPG20 opposite strand
chr14_-_50087312 0.43 ENST00000298289.6
ribosomal protein L36a-like
chr4_+_39640754 0.43 ENST00000529094.1
ENST00000533736.1
RP11-539G18.2
chr5_-_132299290 0.43 ENST00000378595.3
AF4/FMR2 family, member 4
chr12_+_72148614 0.40 ENST00000261263.3
RAB21, member RAS oncogene family
chr10_-_120840309 0.39 ENST00000369144.3
eukaryotic translation initiation factor 3, subunit A
chr11_-_64889252 0.39 ENST00000525297.1
ENST00000529259.1
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
chr8_+_29953163 0.37 ENST00000518192.1
leptin receptor overlapping transcript-like 1
chr13_-_45915221 0.36 ENST00000309246.5
ENST00000379060.4
ENST00000379055.1
ENST00000527226.1
ENST00000379056.1
tumor protein, translationally-controlled 1
chr8_+_97657531 0.36 ENST00000519900.1
ENST00000517742.1
carboxypeptidase Q
chr8_-_94928861 0.35 ENST00000607097.1
microRNA 378d-2
chr9_+_114393581 0.35 ENST00000313525.3
DnaJ (Hsp40) homolog, subfamily C , member 25
chr17_-_15466742 0.35 ENST00000584811.1
ENST00000419890.2
trans-golgi network vesicle protein 23 homolog C (S. cerevisiae)
chr14_+_65016620 0.34 ENST00000298705.1
protein phosphatase 1, regulatory subunit 36
chr6_+_32937083 0.32 ENST00000456339.1
bromodomain containing 2
chr3_+_170075436 0.32 ENST00000476188.1
ENST00000259119.4
ENST00000426052.2
SKI-like oncogene
chr8_+_94929273 0.31 ENST00000518573.1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr19_+_1261106 0.30 ENST00000588411.1
cold inducible RNA binding protein
chr8_+_29952914 0.30 ENST00000321250.8
ENST00000518001.1
ENST00000520682.1
ENST00000442880.2
ENST00000523116.1
leptin receptor overlapping transcript-like 1
chr9_+_114393634 0.30 ENST00000556107.1
ENST00000374294.3
DnaJ (Hsp40) homolog, subfamily C , member 25
DNAJC25-GNG10 readthrough
chr4_+_128982416 0.29 ENST00000326639.6
La ribonucleoprotein domain family, member 1B
chr16_+_58535372 0.29 ENST00000566656.1
ENST00000566618.1
NDRG family member 4
chr21_-_46237883 0.29 ENST00000397893.3
small ubiquitin-like modifier 3
chr6_-_86353510 0.29 ENST00000444272.1
synaptotagmin binding, cytoplasmic RNA interacting protein
chr10_+_27793257 0.28 ENST00000375802.3
RAB18, member RAS oncogene family
chr22_+_38864041 0.28 ENST00000216014.4
ENST00000409006.3
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr19_+_16186903 0.28 ENST00000588507.1
tropomyosin 4
chr6_-_151773232 0.28 ENST00000444024.1
ENST00000367303.4
required for meiotic nuclear division 1 homolog (S. cerevisiae)
chr11_+_20409227 0.28 ENST00000437750.2
protein arginine methyltransferase 3
chr21_-_38445470 0.27 ENST00000399098.1
phosphatidylinositol glycan anchor biosynthesis, class P
chr3_-_121468513 0.27 ENST00000494517.1
ENST00000393667.3
golgin B1
chr7_-_8301768 0.27 ENST00000265577.7
islet cell autoantigen 1, 69kDa
chrX_+_134478706 0.27 ENST00000370761.3
ENST00000339249.4
ENST00000370760.3
zinc finger protein 449
chr1_-_193028426 0.27 ENST00000367450.3
ENST00000530098.2
ENST00000367451.4
ENST00000367448.1
ENST00000367449.1
ubiquitin carboxyl-terminal hydrolase L5
chr21_+_38445539 0.27 ENST00000418766.1
ENST00000450533.1
ENST00000438055.1
ENST00000355666.1
ENST00000540756.1
ENST00000399010.1
tetratricopeptide repeat domain 3
chr12_+_46777450 0.26 ENST00000551503.1
RP11-96H19.1
chr6_+_24775641 0.25 ENST00000378054.2
ENST00000476555.1
geminin, DNA replication inhibitor
chr14_-_35183755 0.25 ENST00000555765.1
cofilin 2 (muscle)
chr8_-_38126635 0.24 ENST00000529359.1
phosphatidic acid phosphatase type 2 domain containing 1B
chr1_-_193028632 0.24 ENST00000421683.1
ubiquitin carboxyl-terminal hydrolase L5
chr4_-_668108 0.24 ENST00000304312.4
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E
chr4_+_128982430 0.24 ENST00000512292.1
ENST00000508819.1
La ribonucleoprotein domain family, member 1B
chrX_+_100663243 0.24 ENST00000316594.5
heterogeneous nuclear ribonucleoprotein H2 (H')
chr12_-_56709674 0.24 ENST00000551286.1
ENST00000549318.1
canopy FGF signaling regulator 2
Uncharacterized protein
chr7_-_8301869 0.24 ENST00000402384.3
islet cell autoantigen 1, 69kDa
chr20_+_33292507 0.24 ENST00000414082.1
tumor protein p53 inducible nuclear protein 2
chr8_+_61429728 0.24 ENST00000529579.1
RAB2A, member RAS oncogene family
chrX_+_108780062 0.23 ENST00000372106.1
nuclear transport factor 2-like export factor 2
chr2_-_242255117 0.23 ENST00000420451.1
ENST00000417540.1
ENST00000310931.4
high density lipoprotein binding protein
chrX_+_108780347 0.23 ENST00000372103.1
nuclear transport factor 2-like export factor 2
chr4_-_83350580 0.23 ENST00000349655.4
ENST00000602300.1
heterogeneous nuclear ribonucleoprotein D-like
chr21_-_46237959 0.23 ENST00000397898.3
ENST00000411651.2
small ubiquitin-like modifier 3
chr11_+_1891380 0.23 ENST00000429923.1
ENST00000418975.1
ENST00000406638.2
lymphocyte-specific protein 1
chr4_-_99850243 0.23 ENST00000280892.6
ENST00000511644.1
ENST00000504432.1
ENST00000505992.1
eukaryotic translation initiation factor 4E
chr4_-_83351005 0.22 ENST00000295470.5
heterogeneous nuclear ribonucleoprotein D-like
chr17_+_33914424 0.22 ENST00000590432.1
adaptor-related protein complex 2, beta 1 subunit
chr15_+_30375158 0.22 ENST00000341650.6
ENST00000567927.1
golgin A8 family, member J
chr3_-_197024965 0.22 ENST00000392382.2
discs, large homolog 1 (Drosophila)
chr1_-_185126037 0.22 ENST00000367506.5
ENST00000367504.3
tRNA methyltransferase 1 homolog (S. cerevisiae)-like
chr17_+_66511540 0.22 ENST00000588188.2
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr9_+_111696664 0.22 ENST00000374624.3
ENST00000445175.1
family with sequence similarity 206, member A
chr6_-_135818764 0.22 ENST00000488690.2
Abelson helper integration site 1
chr8_-_17104099 0.22 ENST00000524358.1
CCR4-NOT transcription complex, subunit 7
chr10_-_31320840 0.22 ENST00000375311.1
zinc finger protein 438
chr22_-_39096981 0.22 ENST00000427389.1
Josephin domain containing 1
chr2_-_40006289 0.22 ENST00000260619.6
ENST00000454352.2
THUMP domain containing 2
chr3_-_121468602 0.22 ENST00000340645.5
golgin B1
chr5_-_99870890 0.21 ENST00000499025.1
CTD-2001C12.1
chr19_+_19516561 0.21 ENST00000457895.2
GATA zinc finger domain containing 2A
chr14_+_24600484 0.21 ENST00000267426.5
fat storage-inducing transmembrane protein 1
chr17_-_49337392 0.21 ENST00000376381.2
ENST00000586178.1
mbt domain containing 1
chr12_-_51566849 0.21 ENST00000549867.1
ENST00000307660.4
transcription factor CP2
chr2_-_40006357 0.21 ENST00000505747.1
THUMP domain containing 2
chr22_-_44258280 0.21 ENST00000540422.1
sulfotransferase family 4A, member 1
chr9_+_100818976 0.21 ENST00000210444.5
N-acetylneuraminic acid synthase
chr2_+_118846008 0.20 ENST00000245787.4
insulin induced gene 2
chr8_-_144099795 0.20 ENST00000522060.1
ENST00000517833.1
ENST00000502167.2
ENST00000518831.1
RP11-273G15.2
chr7_-_8301682 0.20 ENST00000396675.3
ENST00000430867.1
islet cell autoantigen 1, 69kDa
chr17_+_66511224 0.20 ENST00000588178.1
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr11_-_118927561 0.20 ENST00000530473.1
hypoxia up-regulated 1
chr4_-_169931393 0.20 ENST00000504480.1
ENST00000306193.3
carbonyl reductase 4
chr22_+_42394780 0.20 ENST00000328823.9
WBP2 N-terminal like
chr13_-_49107303 0.20 ENST00000344532.3
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr18_+_32621324 0.19 ENST00000300249.5
ENST00000538170.2
ENST00000588910.1
microtubule-associated protein, RP/EB family, member 2
chrX_-_102941596 0.19 ENST00000441076.2
ENST00000422355.1
ENST00000442614.1
ENST00000422154.2
ENST00000451301.1
mortality factor 4 like 2
chr1_-_226187013 0.19 ENST00000272091.7
SDE2 telomere maintenance homolog (S. pombe)
chr21_-_46238034 0.19 ENST00000332859.6
small ubiquitin-like modifier 3
chr3_+_169684553 0.18 ENST00000337002.4
ENST00000480708.1
SEC62 homolog (S. cerevisiae)
chr7_+_92861653 0.18 ENST00000251739.5
ENST00000305866.5
ENST00000544910.1
ENST00000541136.1
ENST00000458530.1
ENST00000535481.1
ENST00000317751.6
coiled-coil domain containing 132
chr8_-_41909496 0.18 ENST00000265713.2
ENST00000406337.1
ENST00000396930.3
ENST00000485568.1
ENST00000426524.1
K(lysine) acetyltransferase 6A
chr8_+_98656693 0.18 ENST00000519934.1
metadherin
chr6_-_86352982 0.18 ENST00000369622.3
synaptotagmin binding, cytoplasmic RNA interacting protein
chr12_+_1100449 0.18 ENST00000360905.4
ELKS/RAB6-interacting/CAST family member 1
chr13_+_114238997 0.18 ENST00000538138.1
ENST00000375370.5
transcription factor Dp-1
chr7_-_27169801 0.18 ENST00000511914.1
homeobox A4
chr11_+_20409070 0.18 ENST00000331079.6
protein arginine methyltransferase 3
chr19_-_9811347 0.18 ENST00000585964.1
ENST00000457674.2
ENST00000590544.1
zinc finger protein 812
chr8_+_109455845 0.18 ENST00000220853.3
ER membrane protein complex subunit 2
chr13_+_53226963 0.18 ENST00000343788.6
ENST00000535397.1
ENST00000310528.8
SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)
chr4_+_128982490 0.18 ENST00000394288.3
ENST00000432347.2
ENST00000264584.5
ENST00000441387.1
ENST00000427266.1
ENST00000354456.3
La ribonucleoprotein domain family, member 1B
chr12_+_110562135 0.18 ENST00000361948.4
ENST00000552912.1
ENST00000242591.5
ENST00000546374.1
intraflagellar transport 81 homolog (Chlamydomonas)
chr12_+_112451222 0.18 ENST00000552052.1
endoplasmic reticulum protein 29
chr6_-_90062543 0.18 ENST00000435041.2
ubiquitin-conjugating enzyme E2, J1
chr2_-_55276320 0.18 ENST00000357376.3
reticulon 4
chr1_-_193028621 0.17 ENST00000367455.4
ENST00000367454.1
ubiquitin carboxyl-terminal hydrolase L5
chr2_+_42396574 0.17 ENST00000401738.3
echinoderm microtubule associated protein like 4
chr14_+_64970662 0.17 ENST00000556965.1
ENST00000554015.1
zinc finger and BTB domain containing 1
chr5_+_94890778 0.17 ENST00000380009.4
arylsulfatase family, member K
chr2_+_223726281 0.17 ENST00000413316.1
acyl-CoA synthetase long-chain family member 3
chr7_+_128379449 0.17 ENST00000479257.1
calumenin
chr5_+_122110691 0.17 ENST00000379516.2
ENST00000505934.1
ENST00000514949.1
sorting nexin 2
chr14_-_35183886 0.17 ENST00000298159.6
cofilin 2 (muscle)
chr21_-_38445443 0.17 ENST00000360525.4
phosphatidylinositol glycan anchor biosynthesis, class P
chrX_+_102631844 0.17 ENST00000372634.1
ENST00000299872.7
nerve growth factor receptor (TNFRSF16) associated protein 1
chr2_-_98612350 0.17 ENST00000186436.5
transmembrane protein 131
chr17_-_57184064 0.17 ENST00000262294.7
tripartite motif containing 37
chr12_+_1100370 0.17 ENST00000543086.3
ENST00000546231.2
ENST00000397203.2
ELKS/RAB6-interacting/CAST family member 1
chr1_+_222791417 0.17 ENST00000344922.5
ENST00000344441.6
ENST00000344507.1
melanoma inhibitory activity family, member 3
chr2_+_242254679 0.16 ENST00000428282.1
ENST00000360051.3
septin 2
chr15_-_74374891 0.16 ENST00000290438.3
golgin A6 family, member A
chr10_+_121410882 0.16 ENST00000369085.3
BCL2-associated athanogene 3
chr21_-_38445011 0.16 ENST00000464265.1
ENST00000399102.1
phosphatidylinositol glycan anchor biosynthesis, class P
chr5_-_99870932 0.16 ENST00000504833.1
CTD-2001C12.1
chr9_-_77643189 0.16 ENST00000376837.3
chromosome 9 open reading frame 41
chr3_-_33759541 0.16 ENST00000468888.2
cytoplasmic linker associated protein 2
chr7_+_116593568 0.16 ENST00000446490.1
suppression of tumorigenicity 7
chr5_+_133984462 0.16 ENST00000398844.2
ENST00000322887.4
SEC24 family member A
chr14_-_50053081 0.16 ENST00000396020.3
ENST00000245458.6
ribosomal protein S29
chr5_+_41904431 0.16 ENST00000381647.2
chromosome 5 open reading frame 51
chr16_+_14294187 0.16 ENST00000573051.1
MKL/myocardin-like 2
chr4_+_1873155 0.15 ENST00000507820.1
ENST00000514045.1
Wolf-Hirschhorn syndrome candidate 1
chr10_+_27793197 0.15 ENST00000356940.6
ENST00000535776.1
RAB18, member RAS oncogene family
chr17_-_7197881 0.15 ENST00000007699.5
Y box binding protein 2
chr13_-_49107205 0.15 ENST00000544904.1
ENST00000430805.2
ENST00000544492.1
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr5_+_34656529 0.15 ENST00000513974.1
ENST00000512629.1
retinoic acid induced 14
chr15_-_43785274 0.15 ENST00000413546.1
tumor protein p53 binding protein 1
chr8_+_97657449 0.15 ENST00000220763.5
carboxypeptidase Q
chrX_+_102862834 0.15 ENST00000372627.5
ENST00000243286.3
transcription elongation factor A (SII)-like 3
chr1_+_9599540 0.15 ENST00000302692.6
solute carrier family 25 (pyrimidine nucleotide carrier), member 33
chr1_+_154193325 0.15 ENST00000428931.1
ENST00000441890.1
ENST00000271877.7
ENST00000412596.1
ENST00000368504.1
ENST00000437652.1
ubiquitin associated protein 2-like
chr19_+_49375649 0.15 ENST00000200453.5
protein phosphatase 1, regulatory subunit 15A
chr7_-_100493744 0.15 ENST00000428317.1
ENST00000441605.1
acetylcholinesterase (Yt blood group)
chr2_+_242254507 0.14 ENST00000391973.2
septin 2
chr3_+_150264458 0.14 ENST00000487799.1
ENST00000460851.1
eukaryotic translation initiation factor 2A, 65kDa
chr3_-_139108475 0.14 ENST00000515006.1
ENST00000513274.1
ENST00000514508.1
ENST00000507777.1
ENST00000512153.1
ENST00000333188.5
coatomer protein complex, subunit beta 2 (beta prime)
chr2_-_242255060 0.14 ENST00000413241.1
ENST00000423693.1
ENST00000428482.1
high density lipoprotein binding protein
chr7_-_8302164 0.14 ENST00000447326.1
ENST00000406470.2
islet cell autoantigen 1, 69kDa
chr2_-_242212227 0.14 ENST00000427007.1
ENST00000458564.1
ENST00000452065.1
ENST00000427183.2
ENST00000426343.1
ENST00000422080.1
ENST00000449504.1
ENST00000449864.1
ENST00000391975.1
high density lipoprotein binding protein
chr12_-_76953573 0.14 ENST00000549646.1
ENST00000550628.1
ENST00000553139.1
ENST00000261183.3
ENST00000393250.4
oxysterol binding protein-like 8
chr15_+_23255242 0.14 ENST00000450802.3
golgin A8 family, member I
chr1_+_185126291 0.14 ENST00000367500.4
SWT1 RNA endoribonuclease homolog (S. cerevisiae)
chr12_-_110011288 0.14 ENST00000540016.1
ENST00000266839.5
methylmalonic aciduria (cobalamin deficiency) cblB type
chr2_-_242254595 0.14 ENST00000441124.1
ENST00000391976.2
high density lipoprotein binding protein
chr12_+_1100710 0.14 ENST00000589132.1
ELKS/RAB6-interacting/CAST family member 1
chr17_-_57184260 0.14 ENST00000376149.3
ENST00000393066.3
tripartite motif containing 37
chr12_-_123380610 0.14 ENST00000535765.1
vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr3_+_100211412 0.14 ENST00000323523.4
ENST00000403410.1
ENST00000449609.1
transmembrane protein 45A
chr6_-_86352642 0.14 ENST00000355238.6
synaptotagmin binding, cytoplasmic RNA interacting protein
chr7_-_100808843 0.14 ENST00000249330.2
VGF nerve growth factor inducible
chr3_-_33759699 0.14 ENST00000399362.4
ENST00000359576.5
ENST00000307312.7
cytoplasmic linker associated protein 2
chr2_-_182521699 0.14 ENST00000374969.2
ENST00000339098.5
ENST00000374970.2
ceramide kinase-like
chr5_+_34656569 0.13 ENST00000428746.2
retinoic acid induced 14
chr15_-_82641706 0.13 ENST00000439287.4
golgin A6 family-like 10
chrX_+_122993657 0.13 ENST00000434753.3
ENST00000430625.1
X-linked inhibitor of apoptosis
chr14_+_68086515 0.13 ENST00000261783.3
arginase 2
chr19_+_10222189 0.13 ENST00000321826.4
purinergic receptor P2Y, G-protein coupled, 11
chr3_-_129158676 0.13 ENST00000393278.2
methyl-CpG binding domain protein 4
chr20_+_39657454 0.13 ENST00000361337.2
topoisomerase (DNA) I
chr4_+_108745711 0.13 ENST00000394684.4
sphingomyelin synthase 2
chr17_+_30348024 0.13 ENST00000327564.7
ENST00000584368.1
ENST00000394713.3
ENST00000341671.7
leucine rich repeat containing 37B
chr17_+_65821636 0.13 ENST00000544778.2
bromodomain PHD finger transcription factor
chr3_+_129158926 0.13 ENST00000347300.2
ENST00000296266.3
intraflagellar transport 122 homolog (Chlamydomonas)
chr2_+_216176761 0.13 ENST00000540518.1
ENST00000435675.1
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr15_-_40213080 0.13 ENST00000561100.1
G protein-coupled receptor 176
chr8_-_17104356 0.13 ENST00000361272.4
ENST00000523917.1
CCR4-NOT transcription complex, subunit 7
chr3_+_184529929 0.13 ENST00000287546.4
ENST00000437079.3
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr19_+_32836499 0.13 ENST00000311921.4
ENST00000544431.1
ENST00000355898.5
zinc finger protein 507
chr11_+_112097069 0.13 ENST00000280362.3
ENST00000525803.1
6-pyruvoyltetrahydropterin synthase
chr1_+_87170577 0.13 ENST00000482504.1
SH3-domain GRB2-like endophilin B1
chr8_+_61429416 0.13 ENST00000262646.7
ENST00000531289.1
RAB2A, member RAS oncogene family
chr14_+_31091511 0.13 ENST00000544052.2
ENST00000421551.3
ENST00000541123.1
ENST00000557076.1
ENST00000553693.1
ENST00000396629.2
sec1 family domain containing 1
chr5_+_34656450 0.13 ENST00000514527.1
retinoic acid induced 14
chr19_-_15442701 0.13 ENST00000594841.1
ENST00000601941.1
bromodomain containing 4
chr2_+_183580954 0.12 ENST00000264065.7
DnaJ (Hsp40) homolog, subfamily C, member 10
chr12_-_76953513 0.12 ENST00000547540.1
oxysterol binding protein-like 8
chr17_+_18684563 0.12 ENST00000476139.1
trans-golgi network vesicle protein 23 homolog B (S. cerevisiae)
chr7_+_99102573 0.12 ENST00000394170.2
zinc finger with KRAB and SCAN domains 5
chr8_+_133787586 0.12 ENST00000395379.1
ENST00000395386.2
ENST00000337920.4
PHD finger protein 20-like 1
chr15_-_23692381 0.12 ENST00000567107.1
ENST00000345070.5
ENST00000312015.5
golgin A6 family-like 2
chr12_-_120662499 0.12 ENST00000552550.1
paxillin
chr19_-_42927251 0.12 ENST00000597001.1
lipase, hormone-sensitive
chr18_+_56530794 0.12 ENST00000590285.1
ENST00000586085.1
ENST00000589288.1
zinc finger protein 532
chr22_-_39096925 0.12 ENST00000456626.1
ENST00000412832.1
Josephin domain containing 1
chr17_-_15466850 0.12 ENST00000438826.3
ENST00000225576.3
ENST00000519970.1
ENST00000518321.1
ENST00000428082.2
ENST00000522212.2
trans-golgi network vesicle protein 23 homolog C (S. cerevisiae)
TVP23C-CDRT4 readthrough
chr12_-_125398654 0.12 ENST00000541645.1
ENST00000540351.1
ubiquitin C

Network of associatons between targets according to the STRING database.

First level regulatory network of ATF6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0002188 translation reinitiation(GO:0002188)
0.1 0.5 GO:1903381 neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0036483) regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903381) negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903382)
0.1 0.3 GO:0039022 pronephric nephron morphogenesis(GO:0039007) pronephric nephron tubule morphogenesis(GO:0039008) pronephric duct development(GO:0039022) pronephric duct morphogenesis(GO:0039023) Kupffer's vesicle development(GO:0070121)
0.1 0.7 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.1 0.2 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.1 0.3 GO:2000174 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.1 0.6 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.2 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.1 0.4 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.1 0.3 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.1 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 0.1 GO:1902310 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0 0.1 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 0.1 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.3 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.4 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.0 0.7 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.0 0.5 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.1 GO:2001247 positive regulation of phosphatidylcholine biosynthetic process(GO:2001247)
0.0 0.2 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.0 0.2 GO:0035720 intraciliary anterograde transport(GO:0035720) ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0 0.1 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.0 0.1 GO:0015728 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.0 0.2 GO:0009386 translational attenuation(GO:0009386)
0.0 0.2 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.1 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.0 0.1 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.3 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.2 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.0 0.2 GO:0043335 protein unfolding(GO:0043335)
0.0 0.1 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.1 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0 0.1 GO:1901993 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.1 GO:1990637 response to prolactin(GO:1990637)
0.0 0.9 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.1 GO:1903461 Okazaki fragment processing involved in mitotic DNA replication(GO:1903461)
0.0 0.1 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
0.0 0.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.2 GO:0021553 olfactory nerve development(GO:0021553)
0.0 0.2 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.2 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0 0.7 GO:0048853 forebrain morphogenesis(GO:0048853)
0.0 0.1 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.3 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.6 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.4 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
0.0 0.5 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.4 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.2 GO:0052055 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0 0.3 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.7 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.4 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:1902990 leading strand elongation(GO:0006272) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.0 0.1 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.3 GO:0044597 polyketide metabolic process(GO:0030638) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.0 0.2 GO:0043622 cortical microtubule organization(GO:0043622)
0.0 0.2 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.1 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0 0.1 GO:1902824 cleavage furrow ingression(GO:0036090) positive regulation of late endosome to lysosome transport(GO:1902824)
0.0 0.1 GO:0044828 negative regulation by host of viral process(GO:0044793) negative regulation by host of viral genome replication(GO:0044828)
0.0 0.5 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.1 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.2 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.1 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.2 GO:0045714 regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045714)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0007621 negative regulation of female receptivity(GO:0007621) female courtship behavior(GO:0008050)
0.0 0.3 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.2 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.1 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.2 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.1 GO:0045720 negative regulation of integrin biosynthetic process(GO:0045720)
0.0 0.1 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 1.0 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
0.0 0.0 GO:1903895 negative regulation of IRE1-mediated unfolded protein response(GO:1903895)
0.0 0.6 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:0090166 Golgi disassembly(GO:0090166) spindle assembly involved in meiosis(GO:0090306)
0.0 0.2 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.1 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.2 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.0 0.1 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.3 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655)
0.0 0.3 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.0 0.2 GO:0071501 SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.1 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.2 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0075341 host cell PML body(GO:0075341)
0.1 0.4 GO:0043614 multi-eIF complex(GO:0043614)
0.1 0.6 GO:0097452 GAIT complex(GO:0097452)
0.1 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 0.2 GO:0005745 m-AAA complex(GO:0005745)
0.1 0.3 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.4 GO:0045298 tubulin complex(GO:0045298)
0.1 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.7 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0 0.9 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.9 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.4 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.3 GO:0033263 CORVET complex(GO:0033263)
0.0 0.1 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 0.2 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.3 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.4 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.5 GO:0097227 sperm annulus(GO:0097227)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.4 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.2 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.4 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.7 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.4 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.6 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)
0.0 0.1 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.0 0.1 GO:0019012 virion(GO:0019012) virion part(GO:0044423)
0.0 0.2 GO:0097025 lateral loop(GO:0043219) MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.2 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.0 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.0 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.3 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.2 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.1 GO:0030126 COPI vesicle coat(GO:0030126)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0003955 NAD(P)H dehydrogenase (quinone) activity(GO:0003955) 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.1 0.5 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.7 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.7 GO:0031386 protein tag(GO:0031386)
0.1 0.5 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.1 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0 1.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0 0.5 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.2 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.1 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.0 0.1 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.0 0.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.2 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.2 GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.0 0.2 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.3 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0052812 phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.2 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.1 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.0 0.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.4 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.1 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.1 GO:0031626 beta-endorphin binding(GO:0031626)
0.0 0.2 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.1 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.0 0.6 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.2 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 0.3 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.8 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.2 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.2 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.2 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.7 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.0 GO:0097258 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 0.1 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.1 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.2 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 1.3 GO:0019003 GDP binding(GO:0019003)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.7 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.5 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.4 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.8 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.2 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.3 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription