Motif ID: ZNF423.p2

Z-value: 2.537


Transcription factors associated with ZNF423.p2:

Gene SymbolEntrez IDGene Name
ZNF423 23090 zinc finger protein 423



Activity profile for motif ZNF423.p2.

activity profile for motif ZNF423.p2


Sorted Z-values histogram for motif ZNF423.p2

Sorted Z-values for motif ZNF423.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF423.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_-_33178987 5.046 HNF1B
HNF1 homeobox B
chr5_+_170668892 4.674 NM_021025
 TLX3
T-cell leukemia homeobox 3
chr20_-_21326046 4.388 NM_033176
 NKX2-4
NK2 homeobox 4
chr7_-_19151509 3.763 NM_152898
 FERD3L
Fer3-like (Drosophila)
chr12_+_109956210 3.509 NM_015267
 CUX2
cut-like homeobox 2
chr15_-_81113676 3.328 NM_030594
 CPEB1
cytoplasmic polyadenylation element binding protein 1
chr15_+_62230962 3.139 NM_024798
 SNX22
sorting nexin 22
chr19_+_19510056 3.080 NM_153221
 CILP2
cartilage intermediate layer protein 2
chr19_+_19510098 2.985 CILP2
cartilage intermediate layer protein 2
chr17_-_35017650 2.975 NEUROD2
neurogenic differentiation 2
chr8_-_144313293 2.959 NM_001130478
 LY6H
lymphocyte antigen 6 complex, locus H
chr19_+_14405100 2.887 NM_002741
 PKN1
protein kinase N1
chr22_+_38183480 2.739 MGAT3
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chrX_+_136475979 2.707 NM_003413
 ZIC3
Zic family member 3 (odd-paired homolog, Drosophila)
chr17_-_35017691 2.553 NM_006160
 NEUROD2
neurogenic differentiation 2
chr3_+_6877812 2.533 GRM7
glutamate receptor, metabotropic 7
chr10_-_120345148 2.514 NM_004248
 PRLHR
prolactin releasing hormone receptor
chr3_+_6877797 2.504 NM_000844
NM_181874
 GRM7

glutamate receptor, metabotropic 7

chr19_-_55524445 2.465 NM_004977
 KCNC3
potassium voltage-gated channel, Shaw-related subfamily, member 3
chr5_+_68823874 2.437 NM_002538
 OCLN
occludin

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 23 entries
Enrichment   P-value GO Accession GO Term
28.02 7.87e-03 GO:0033628 regulation of cell adhesion mediated by integrin
7.06 4.13e-03 GO:0006813 potassium ion transport
4.39 2.59e-04 GO:0007417 central nervous system development
3.90 2.37e-02 GO:0007268 synaptic transmission
3.80 2.26e-04 GO:0030182 neuron differentiation
3.74 1.85e-02 GO:0019226 transmission of nerve impulse
3.74 1.85e-02 GO:0035637 multicellular organismal signaling
3.69 6.95e-11 GO:0007399 nervous system development
3.68 5.73e-03 GO:0048666 neuron development
3.39 3.80e-04 GO:0048699 generation of neurons
3.34 2.61e-04 GO:0022008 neurogenesis
3.31 3.15e-04 GO:0048468 cell development
2.96 9.89e-03 GO:0006811 ion transport
2.95 4.98e-02 GO:0007267 cell-cell signaling
2.74 1.90e-02 GO:0007154 cell communication
2.40 1.27e-02 GO:0009653 anatomical structure morphogenesis
2.39 4.94e-07 GO:0048731 system development
2.31 2.51e-07 GO:0048856 anatomical structure development
2.28 1.74e-03 GO:0030154 cell differentiation
2.22 3.28e-03 GO:0048869 cellular developmental process

Gene overrepresentation in compartment category:

Showing 1 to 11 of 11 entries
Enrichment   P-value GO Accession GO Term
79.38 2.55e-02 GO:0032045 guanyl-nucleotide exchange factor complex
22.68 3.12e-03 GO:0005891 voltage-gated calcium channel complex
16.43 1.17e-02 GO:0034704 calcium channel complex
8.83 2.50e-05 GO:0034703 cation channel complex
8.22 1.11e-02 GO:0008076 voltage-gated potassium channel complex
8.22 1.11e-02 GO:0034705 potassium channel complex
6.88 2.29e-05 GO:0034702 ion channel complex
5.64 3.09e-02 GO:0045211 postsynaptic membrane
2.05 3.09e-03 GO:0044459 plasma membrane part
1.70 1.74e-03 GO:0005886 plasma membrane
1.68 2.70e-03 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 20 of 22 entries
Enrichment   P-value GO Accession GO Term
18.32 1.04e-02 GO:0005245 voltage-gated calcium channel activity
10.07 4.46e-07 GO:0022843 voltage-gated cation channel activity
8.51 3.14e-03 GO:0005249 voltage-gated potassium channel activity
8.28 1.03e-06 GO:0005244 voltage-gated ion channel activity
8.28 1.03e-06 GO:0022832 voltage-gated channel activity
7.57 1.87e-03 GO:0005267 potassium channel activity
5.94 6.13e-06 GO:0022836 gated channel activity
5.87 6.00e-05 GO:0005261 cation channel activity
4.69 1.28e-04 GO:0005216 ion channel activity
4.62 1.56e-04 GO:0022838 substrate-specific channel activity
4.48 2.28e-04 GO:0015267 channel activity
4.47 2.35e-04 GO:0022803 passive transmembrane transporter activity
3.55 2.01e-03 GO:0008324 cation transmembrane transporter activity
3.31 1.41e-03 GO:0043565 sequence-specific DNA binding
3.03 4.61e-03 GO:0015075 ion transmembrane transporter activity
2.94 5.41e-04 GO:0001071 nucleic acid binding transcription factor activity
2.94 5.41e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
2.74 1.07e-02 GO:0022891 substrate-specific transmembrane transporter activity
2.68 9.51e-03 GO:0022857 transmembrane transporter activity
2.63 7.82e-03 GO:0030528 transcription regulator activity