Motif ID: ZEB1.p2

Z-value: 3.291


Transcription factors associated with ZEB1.p2:

Gene SymbolEntrez IDGene Name
ZEB1 6935 zinc finger E-box binding homeobox 1



Activity profile for motif ZEB1.p2.

activity profile for motif ZEB1.p2


Sorted Z-values histogram for motif ZEB1.p2

Sorted Z-values for motif ZEB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZEB1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr22_+_38720881 10.127 NM_138435
FAM83F
family with sequence similarity 83, member F
chr19_+_6415259 9.831 NM_139161
NM_174881
CRB3

crumbs homolog 3 (Drosophila)

chr1_-_3556420 8.691 NM_017818
WDR8
WD repeat domain 8
chr8_+_120289735 6.807 NM_052886
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr7_-_22363036 5.763 NM_012294
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr17_+_26839143 5.432 RAB11FIP4
RAB11 family interacting protein 4 (class II)
chr1_+_60053050 5.277 NM_015888
HOOK1
hook homolog 1 (Drosophila)
chr1_+_1971762 5.062 NM_002744
PRKCZ
protein kinase C, zeta
chr2_-_73350103 5.012 NM_001080410
FBXO41
F-box protein 41
chr2_+_74595073 4.856 NM_016170
TLX2
T-cell leukemia homeobox 2
chr3_-_42280442 4.414 NM_001174138
CCK
cholecystokinin
chr18_-_45975163 4.002 NM_001080467
MYO5B
myosin VB
chr11_+_45900731 3.937 GYLTL1B
glycosyltransferase-like 1B
chr4_-_5942818 3.910 CRMP1
collapsin response mediator protein 1
chr11_-_65895640 3.891 NM_001532
SLC29A2
solute carrier family 29 (nucleoside transporters), member 2
chr19_+_7566698 3.761 NM_001080429
NM_020902
KIAA1543

KIAA1543

chr19_+_40431618 3.738 LSR
lipolysis stimulated lipoprotein receptor
chr19_+_40431359 3.711 NM_015925
NM_205834
NM_205835
LSR


lipolysis stimulated lipoprotein receptor


chr19_+_40431122 3.646 LSR
lipolysis stimulated lipoprotein receptor
chr21_-_38954433 3.608 ERG
v-ets erythroblastosis virus E26 oncogene homolog (avian)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 32 entries
Enrichment   P-value GO Accession GO Term
21.06 3.11e-02 GO:0001662 behavioral fear response
19.31 4.59e-02 GO:0002209 behavioral defense response
13.16 3.66e-02 GO:0016338 calcium-independent cell-cell adhesion
3.32 3.60e-02 GO:0016337 cell-cell adhesion
3.30 7.29e-03 GO:0007420 brain development
3.26 1.69e-04 GO:0007417 central nervous system development
3.20 3.87e-03 GO:0016477 cell migration
3.04 5.13e-03 GO:0048870 cell motility
3.04 5.13e-03 GO:0051674 localization of cell
2.86 1.94e-04 GO:0030182 neuron differentiation
2.77 2.58e-05 GO:0048699 generation of neurons
2.75 1.22e-05 GO:0022008 neurogenesis
2.72 1.64e-05 GO:0048468 cell development
2.68 1.54e-02 GO:0048666 neuron development
2.64 8.50e-03 GO:0032989 cellular component morphogenesis
2.64 2.98e-02 GO:0006928 cellular component movement
2.58 1.45e-08 GO:0007399 nervous system development
2.38 6.51e-03 GO:0040011 locomotion
2.28 1.76e-08 GO:0030154 cell differentiation
2.26 3.11e-04 GO:0051239 regulation of multicellular organismal process

Gene overrepresentation in compartment category:

Showing 1 to 10 of 10 entries
Enrichment   P-value GO Accession GO Term
15.24 2.71e-03 GO:0030057 desmosome
7.41 5.10e-05 GO:0043296 apical junction complex
7.16 7.27e-05 GO:0016327 apicolateral plasma membrane
6.86 1.21e-03 GO:0005923 tight junction
6.86 1.21e-03 GO:0070160 occluding junction
5.88 4.39e-08 GO:0005911 cell-cell junction
2.75 4.33e-04 GO:0030054 cell junction
1.73 2.45e-03 GO:0044459 plasma membrane part
1.49 2.01e-03 GO:0005886 plasma membrane
1.48 2.13e-03 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 4 of 4 entries
Enrichment   P-value GO Accession GO Term
6.05 3.87e-02 GO:0030165 PDZ domain binding
2.51 2.18e-03 GO:0043565 sequence-specific DNA binding
2.11 8.87e-03 GO:0001071 nucleic acid binding transcription factor activity
2.11 8.87e-03 GO:0003700 sequence-specific DNA binding transcription factor activity