Motif ID: ZBTB16.p2

Z-value: 1.819


Transcription factors associated with ZBTB16.p2:

Gene SymbolEntrez IDGene Name
ZBTB16 7704 zinc finger and BTB domain containing 16



Activity profile for motif ZBTB16.p2.

activity profile for motif ZBTB16.p2


Sorted Z-values histogram for motif ZBTB16.p2

Sorted Z-values for motif ZBTB16.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZBTB16.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_10453409 2.848 NM_013431
 KLRC4-KLRK1
KLRC4
KLRC4-KLRK1 read-through transcript
killer cell lectin-like receptor subfamily C, member 4
chr5_+_57823017 2.779 NM_152687
 GAPT
GRB2-binding adaptor protein, transmembrane
chr9_-_21340885 2.753 NM_021002
 IFNA6
interferon, alpha 6
chr4_-_77176163 2.645 NM_005409
 CXCL11
chemokine (C-X-C motif) ligand 11
chr7_-_92693716 2.547 NM_001039372
 HEPACAM2
HEPACAM family member 2
chr4_+_74520796 2.290 NM_001134
 AFP
alpha-fetoprotein
chr4_-_38460983 2.114 NM_001017388
NM_001195106
NM_001195107
NM_001195108
NM_030956
 TLR10




toll-like receptor 10




chr9_-_21375258 2.090 NM_000605
 IFNA2
interferon, alpha 2
chr18_+_59733724 2.089 NM_005024
 SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr12_-_9987277 2.071 LOC100506159
hypothetical LOC100506159
chr7_+_99263571 2.039 NM_022820
NM_057095
NM_057096
 CYP3A43


cytochrome P450, family 3, subfamily A, polypeptide 43


chr5_-_176760242 1.999 NM_001029886
 PFN3
profilin 3
chr2_-_135498716 1.953 NM_001018046
NM_025052
 YSK4

YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae)

chr16_-_70168449 1.897 NM_000353
 TAT
tyrosine aminotransferase
chr14_+_28311740 1.869 C14orf23
chromosome 14 open reading frame 23
chr17_+_29621352 1.849 NM_006273
 CCL7
chemokine (C-C motif) ligand 7
chr4_-_90978469 1.839 NM_001146055
 SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr12_+_10351683 1.831 NM_002262
NM_007334
 KLRD1

killer cell lectin-like receptor subfamily D, member 1

chr9_+_21430439 1.760 NM_024013
 IFNA1
interferon, alpha 1
chr15_-_72446979 1.644 NM_000781
 CYP11A1
cytochrome P450, family 11, subfamily A, polypeptide 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 38 entries
Enrichment   P-value GO Accession GO Term
86.72 5.74e-17 GO:0060338 regulation of type I interferon-mediated signaling pathway
41.97 4.82e-13 GO:0001959 regulation of cytokine-mediated signaling pathway
41.97 4.82e-13 GO:0060337 type I interferon-mediated signaling pathway
41.97 4.82e-13 GO:0071357 cellular response to type I interferon
41.30 5.82e-13 GO:0034340 response to type I interferon
41.30 5.82e-13 GO:0060759 regulation of response to cytokine stimulus
17.53 3.03e-02 GO:0006968 cellular defense response
16.90 1.42e-08 GO:0009615 response to virus
16.80 1.80e-09 GO:0045088 regulation of innate immune response
15.44 4.92e-09 GO:0019221 cytokine-mediated signaling pathway
13.92 1.65e-08 GO:0071345 cellular response to cytokine stimulus
10.88 5.18e-08 GO:0034097 response to cytokine stimulus
10.19 1.16e-07 GO:0031347 regulation of defense response
9.75 2.84e-10 GO:0050776 regulation of immune response
8.90 6.09e-07 GO:0045087 innate immune response
8.10 1.89e-06 GO:0051707 response to other organism
7.15 2.23e-06 GO:0009607 response to biotic stimulus
7.10 5.87e-03 GO:0006954 inflammatory response
7.02 4.99e-11 GO:0006952 defense response
6.74 2.57e-08 GO:0002682 regulation of immune system process

Gene overrepresentation in compartment category:

Showing 1 to 3 of 3 entries
Enrichment   P-value GO Accession GO Term
5.67 7.85e-08 GO:0005615 extracellular space
4.62 7.26e-07 GO:0044421 extracellular region part
2.95 3.00e-05 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
Enrichment   P-value GO Accession GO Term
177.36 1.10e-11 GO:0005132 interferon-alpha/beta receptor binding
59.13 4.56e-02 GO:0016493 C-C chemokine receptor activity
19.19 9.10e-14 GO:0005126 cytokine receptor binding
16.65 6.57e-12 GO:0005125 cytokine activity
11.69 3.45e-02 GO:0004497 monooxygenase activity
4.20 2.56e-05 GO:0005102 receptor binding