Motif ID: TFAP2B.p2

Z-value: 3.265


Transcription factors associated with TFAP2B.p2:

Gene SymbolEntrez IDGene Name
TFAP2B 7021 transcription factor AP-2 beta (activating enhancer binding protein 2 beta)



Activity profile for motif TFAP2B.p2.

activity profile for motif TFAP2B.p2


Sorted Z-values histogram for motif TFAP2B.p2

Sorted Z-values for motif TFAP2B.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFAP2B.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_55922623 7.199 ZNF713
zinc finger protein 713
chr19_+_39664706 6.177 NM_001080436
WTIP
Wilms tumor 1 interacting protein
chr22_+_48951286 5.886 NM_001160300
NM_052839
PANX2

pannexin 2

chr11_+_359723 5.830 NM_178537
B4GALNT4
beta-1,4-N-acetyl-galactosaminyl transferase 4
chr20_-_60074237 5.553 NM_003185
TAF4
TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
chr17_+_77582774 5.508 NM_005052
RAC3
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr20_-_61933012 5.028 ZBTB46
zinc finger and BTB domain containing 46
chr3_-_130807865 4.856 NM_015103
PLXND1
plexin D1
chr8_+_1699418 4.834 CLN8
ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
chr16_+_88169612 4.300 NM_014427
NM_153636
CPNE7

copine VII

chr8_+_1699276 4.235 NM_018941
CLN8
ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
chr2_+_101680594 4.180 NM_004834
NM_145686
NM_145687
MAP4K4


mitogen-activated protein kinase kinase kinase kinase 4


chr4_-_809879 3.945 NM_006651
CPLX1
complexin 1
chr9_+_123501186 3.503 DAB2IP
DAB2 interacting protein
chr7_-_525556 3.411 PDGFA
platelet-derived growth factor alpha polypeptide
chr20_-_60375695 3.306 NM_005560
LAMA5
laminin, alpha 5
chr4_+_3264509 3.294 RGS12
regulator of G-protein signaling 12
chr20_+_8060762 3.185 NM_015192
NM_182734
PLCB1

phospholipase C, beta 1 (phosphoinositide-specific)

chr2_-_110769670 3.171 NM_001164463
NM_005054
RGPD8
RGPD5
RANBP2-like and GRIP domain containing 8
RANBP2-like and GRIP domain containing 5
chr4_+_2031036 3.108 NM_178557
NAT8L
N-acetyltransferase 8-like (GCN5-related, putative)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 42 entries
Enrichment   P-value GO Accession GO Term
4.51 3.68e-02 GO:0035239 tube morphogenesis
4.13 4.18e-03 GO:0035295 tube development
3.64 1.90e-02 GO:0060284 regulation of cell development
3.33 1.67e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
3.29 3.46e-02 GO:0060429 epithelium development
3.18 1.95e-03 GO:0051253 negative regulation of RNA metabolic process
3.10 5.05e-03 GO:0045892 negative regulation of transcription, DNA-dependent
2.92 4.82e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.91 3.10e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
2.90 1.99e-03 GO:0045595 regulation of cell differentiation
2.90 8.90e-03 GO:0009887 organ morphogenesis
2.88 9.43e-03 GO:0010629 negative regulation of gene expression
2.85 2.81e-03 GO:0009890 negative regulation of biosynthetic process
2.85 1.15e-02 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.81 1.40e-02 GO:0051172 negative regulation of nitrogen compound metabolic process
2.79 6.29e-03 GO:0031327 negative regulation of cellular biosynthetic process
2.63 1.12e-02 GO:2000026 regulation of multicellular organismal development
2.52 5.02e-03 GO:0050793 regulation of developmental process
2.51 2.42e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.38 2.97e-02 GO:0031324 negative regulation of cellular metabolic process

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Showing 1 to 4 of 4 entries
Enrichment   P-value GO Accession GO Term
71.24 4.48e-02 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity
2.47 3.54e-04 GO:0030528 transcription regulator activity
2.29 4.85e-03 GO:0001071 nucleic acid binding transcription factor activity
2.29 4.85e-03 GO:0003700 sequence-specific DNA binding transcription factor activity