Motif ID: RREB1.p2

Z-value: 6.512


Transcription factors associated with RREB1.p2:

Gene SymbolEntrez IDGene Name
RREB1 6239 ras responsive element binding protein 1



Activity profile for motif RREB1.p2.

activity profile for motif RREB1.p2


Sorted Z-values histogram for motif RREB1.p2

Sorted Z-values for motif RREB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RREB1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_17665483 13.433 NM_001037535
NM_001037536
NM_001037540
NM_006746
SCML1



sex comb on midleg-like 1 (Drosophila)



chr16_-_3225360 12.578 NM_001145448
NM_198088
NM_001145446
NM_198087
ZNF200



zinc finger protein 200



chr19_-_55914837 11.479


chr4_-_809879 10.811 NM_006651
CPLX1
complexin 1
chr20_+_55359551 10.456 NM_003610
RAE1
RAE1 RNA export 1 homolog (S. pombe)
chr3_+_187917791 10.069 NM_000893
NM_001102416
NM_001166451
KNG1


kininogen 1


chr20_+_55359706 9.929 RAE1
RAE1 RNA export 1 homolog (S. pombe)
chr21_+_42946719 9.555 NM_001001567
NM_001001568
NM_001001569
NM_001001570
NM_001001571
NM_001001572
NM_001001573
NM_001001574
NM_001001575
NM_001001576
NM_001001577
NM_001001578
NM_001001579
NM_001001580
NM_001001581
NM_001001582
NM_001001583
NM_001001584
NM_001001585
NM_002606
PDE9A



















phosphodiesterase 9A



















chr16_-_3225070 9.264 NM_001145447
NM_003454
ZNF200

zinc finger protein 200

chr19_-_51168396 8.642 NM_002516
NOVA2
neuro-oncological ventral antigen 2
chr7_+_44110527 7.867 AEBP1
AE binding protein 1
chr11_-_133786935 7.729 NM_018644
NM_054025
B3GAT1

beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)

chr7_+_44110470 7.708 NM_001129
AEBP1
AE binding protein 1
chr4_-_46086528 7.474 NM_000807
GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr1_-_202647526 7.158 NM_032833
PPP1R15B
protein phosphatase 1, regulatory (inhibitor) subunit 15B
chr16_+_86193993 7.002 NM_020655
JPH3
junctophilin 3
chr19_+_3317589 6.886 NFIC
nuclear factor I/C (CCAAT-binding transcription factor)
chr22_+_48966394 6.858 TRABD
TraB domain containing
chr22_+_48966480 6.731 NM_025204
TRABD
TraB domain containing
chr4_+_191235959 6.705 NM_001177376
DUX4L4
double homeobox 4 like 4

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 99 entries
Enrichment   P-value GO Accession GO Term
11.40 1.36e-02 GO:0017158 regulation of calcium ion-dependent exocytosis
4.21 4.45e-03 GO:0010769 regulation of cell morphogenesis involved in differentiation
4.17 4.94e-03 GO:0022604 regulation of cell morphogenesis
4.05 7.98e-04 GO:0006813 potassium ion transport
4.04 7.38e-03 GO:0042391 regulation of membrane potential
3.72 2.60e-07 GO:0060284 regulation of cell development
3.70 4.33e-06 GO:0051960 regulation of nervous system development
3.59 3.15e-02 GO:0060562 epithelial tube morphogenesis
3.42 4.79e-04 GO:0050767 regulation of neurogenesis
3.42 5.15e-03 GO:0045664 regulation of neuron differentiation
3.07 8.63e-05 GO:0007420 brain development
3.01 5.12e-05 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
2.91 6.38e-06 GO:0019226 transmission of nerve impulse
2.91 6.38e-06 GO:0035637 multicellular organismal signaling
2.89 4.82e-06 GO:0007417 central nervous system development
2.83 1.34e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
2.81 3.56e-03 GO:0007389 pattern specification process
2.79 2.98e-05 GO:0000904 cell morphogenesis involved in differentiation
2.79 6.70e-03 GO:0007411 axon guidance
2.78 2.01e-04 GO:0048812 neuron projection morphogenesis

Gene overrepresentation in compartment category:

Showing 1 to 11 of 11 entries
Enrichment   P-value GO Accession GO Term
4.32 1.03e-02 GO:0008076 voltage-gated potassium channel complex
4.32 1.03e-02 GO:0034705 potassium channel complex
3.55 9.56e-03 GO:0034703 cation channel complex
3.29 7.40e-04 GO:0034702 ion channel complex
3.09 7.71e-07 GO:0045202 synapse
2.86 9.37e-04 GO:0044456 synapse part
2.41 5.80e-03 GO:0043005 neuron projection
2.10 6.72e-03 GO:0030054 cell junction
1.61 3.06e-04 GO:0044459 plasma membrane part
1.37 1.36e-03 GO:0005886 plasma membrane
1.35 3.12e-03 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 20 of 26 entries
Enrichment   P-value GO Accession GO Term
25.64 3.54e-02 GO:0051380 norepinephrine binding
10.69 2.55e-02 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity
10.69 2.55e-02 GO:0019198 transmembrane receptor protein phosphatase activity
4.89 3.46e-04 GO:0005249 voltage-gated potassium channel activity
4.82 2.12e-06 GO:0022843 voltage-gated cation channel activity
4.34 3.00e-04 GO:0005267 potassium channel activity
4.02 1.09e-05 GO:0005244 voltage-gated ion channel activity
4.02 1.09e-05 GO:0022832 voltage-gated channel activity
3.70 9.39e-05 GO:0010843 promoter binding
3.56 1.85e-04 GO:0000975 regulatory region DNA binding
3.56 1.85e-04 GO:0001067 regulatory region nucleic acid binding
3.56 1.85e-04 GO:0044212 transcription regulatory region DNA binding
3.11 2.48e-12 GO:0043565 sequence-specific DNA binding
3.07 9.29e-05 GO:0022836 gated channel activity
2.98 1.18e-03 GO:0005261 cation channel activity
2.96 3.00e-04 GO:0016564 transcription repressor activity
2.78 1.07e-04 GO:0005216 ion channel activity
2.74 1.50e-04 GO:0022838 substrate-specific channel activity
2.66 2.91e-04 GO:0015267 channel activity
2.65 3.07e-04 GO:0022803 passive transmembrane transporter activity