Motif ID: PRRX1,2.p2

Z-value: 2.654


Transcription factors associated with PRRX1,2.p2:

Gene SymbolEntrez IDGene Name
PRRX1 5396 paired related homeobox 1
PRRX2 51450 paired related homeobox 2



Activity profile for motif PRRX1,2.p2.

activity profile for motif PRRX1,2.p2


Sorted Z-values histogram for motif PRRX1,2.p2

Sorted Z-values for motif PRRX1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PRRX1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_35658852 4.803 NM_016300
 ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr3_+_35697432 4.418 NM_198399
 ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr12_-_23993830 3.963 NM_006940
 SOX5
SRY (sex determining region Y)-box 5
chr10_-_69125932 3.658 NM_013266
 CTNNA3
catenin (cadherin-associated protein), alpha 3
chr4_+_74520796 3.286 NM_001134
 AFP
alpha-fetoprotein
chr7_-_83116414 3.195 NM_012431
 SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr6_+_83129641 3.029 NM_006670
 TPBG
trophoblast glycoprotein
chr6_-_130578110 2.985 NM_152552
 SAMD3
sterile alpha motif domain containing 3
chr13_+_22653059 2.939 NM_000231
 SGCG
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
chr6_+_132915522 2.859 NM_053278
 TAAR8
trace amine associated receptor 8
chr1_+_198263352 2.852 NM_003822
NM_205860
 NR5A2

nuclear receptor subfamily 5, group A, member 2

chr2_-_206790871 2.799 NM_001098199
NM_005279
 GPR1

G protein-coupled receptor 1

chr2_+_234490781 2.719 NM_024080
 TRPM8
transient receptor potential cation channel, subfamily M, member 8
chr17_-_36113502 2.697 NM_019016
 KRT24
keratin 24
chr12_+_52708460 2.655 NM_004503
 HOXC6
homeobox C6
chr2_-_180135559 2.646 NM_001113398
 ZNF385B
zinc finger protein 385B
chr6_+_105511615 2.583 NM_001004317
 LIN28B
lin-28 homolog B (C. elegans)
chr3_-_152541129 2.554 NM_176876
 P2RY12
purinergic receptor P2Y, G-protein coupled, 12
chr11_+_113280727 2.531 NM_006028
 HTR3B
5-hydroxytryptamine (serotonin) receptor 3B
chr6_+_50894397 2.470 NM_003221
 TFAP2B
transcription factor AP-2 beta (activating enhancer binding protein 2 beta)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 9 of 9 entries
Enrichment   P-value GO Accession GO Term
42.85 2.56e-02 GO:0060638 mesenchymal-epithelial cell signaling
4.65 8.07e-03 GO:0001501 skeletal system development
2.95 1.05e-02 GO:0009888 tissue development
2.10 3.98e-02 GO:0048513 organ development
2.07 4.50e-04 GO:0048731 system development
1.96 2.36e-04 GO:0007275 multicellular organismal development
1.94 1.60e-03 GO:0048856 anatomical structure development
1.91 4.83e-08 GO:0032501 multicellular organismal process
1.82 2.00e-03 GO:0032502 developmental process

Gene overrepresentation in compartment category:

Showing 1 to 11 of 11 entries
Enrichment   P-value GO Accession GO Term
38.09 6.37e-03 GO:0005916 fascia adherens
28.57 1.64e-02 GO:0014704 intercalated disc
28.57 1.64e-02 GO:0044291 cell-cell contact zone
5.23 7.19e-03 GO:0005911 cell-cell junction
3.75 4.30e-02 GO:0005578 proteinaceous extracellular matrix
3.42 1.23e-03 GO:0030054 cell junction
2.47 1.44e-02 GO:0044421 extracellular region part
2.30 2.39e-05 GO:0044459 plasma membrane part
2.14 9.18e-04 GO:0005576 extracellular region
1.72 6.63e-04 GO:0005886 plasma membrane
1.70 1.06e-03 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 5 of 5 entries
Enrichment   P-value GO Accession GO Term
3.18 2.69e-03 GO:0043565 sequence-specific DNA binding
2.69 2.49e-04 GO:0004888 transmembrane receptor activity
2.57 1.18e-02 GO:0001071 nucleic acid binding transcription factor activity
2.57 1.18e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
2.31 1.01e-03 GO:0004872 receptor activity