Motif ID: POU5F1.p2

Z-value: 1.622


Transcription factors associated with POU5F1.p2:

Gene SymbolEntrez IDGene Name
POU5F1 5460 POU class 5 homeobox 1



Activity profile for motif POU5F1.p2.

activity profile for motif POU5F1.p2


Sorted Z-values histogram for motif POU5F1.p2

Sorted Z-values for motif POU5F1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU5F1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_16649211 4.105 LMO3
LIM domain only 3 (rhombotin-like 2)
chr4_-_110443247 3.354 NM_032518
NM_198721
 COL25A1

collagen, type XXV, alpha 1

chr10_+_68355797 2.738 NM_178011
 LRRTM3
leucine rich repeat transmembrane neuronal 3
chr2_+_5750229 2.646 NM_003108
 SOX11
SRY (sex determining region Y)-box 11
chr15_+_26832300 2.569 LOC100289656
Dexi homolog (mouse) pseudogene
chr17_-_33178987 2.534 HNF1B
HNF1 homeobox B
chr13_-_52320774 2.500 NM_002590
NM_032949
 PCDH8

protocadherin 8

chrX_-_6156655 2.461 NM_181332
 NLGN4X
neuroligin 4, X-linked
chr11_-_3620060 2.457 NM_053017
NM_001079536
 ART5

ADP-ribosyltransferase 5

chr13_-_101852028 2.411 NM_175929
 FGF14
fibroblast growth factor 14
chr13_-_60887210 2.307 PCDH20
protocadherin 20
chr17_+_7494964 2.303 NM_001678
 ATP1B2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr17_+_7495140 2.213 ATP1B2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr17_-_33179118 2.095 NM_000458
NM_001165923
 HNF1B

HNF1 homeobox B

chr4_+_158361185 2.059 NM_000826
NM_001083619
NM_001083620
 GRIA2


glutamate receptor, ionotropic, AMPA 2


chr4_-_41445479 2.025 PHOX2B
paired-like homeobox 2b
chrX_-_33267646 2.022 NM_000109
 DMD
dystrophin
chr4_+_41395493 1.932 LIMCH1
LIM and calponin homology domains 1
chr6_+_105511615 1.905 NM_001004317
 LIN28B
lin-28 homolog B (C. elegans)
chr15_-_86600658 1.809 NM_001007156
NM_001012338
NM_002530
 NTRK3


neurotrophic tyrosine kinase, receptor, type 3



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 49 entries
Enrichment   P-value GO Accession GO Term
51.61 4.51e-04 GO:0060079 regulation of excitatory postsynaptic membrane potential
43.01 9.78e-04 GO:0060078 regulation of postsynaptic membrane potential
25.81 8.03e-03 GO:0051899 membrane depolarization
23.47 1.18e-02 GO:0048663 neuron fate commitment
19.86 2.43e-03 GO:0030902 hindbrain development
10.40 1.12e-02 GO:0048562 embryonic organ morphogenesis
10.07 1.35e-02 GO:0009952 anterior/posterior pattern formation
9.40 1.98e-02 GO:0030900 forebrain development
9.31 1.01e-03 GO:0003002 regionalization
8.99 1.46e-05 GO:0007389 pattern specification process
8.91 7.20e-05 GO:0007610 behavior
8.51 2.57e-05 GO:0007420 brain development
8.39 8.20e-08 GO:0007417 central nervous system development
8.22 1.03e-02 GO:0048568 embryonic organ development
7.49 3.56e-04 GO:0009792 embryo development ending in birth or egg hatching
6.88 3.22e-02 GO:0007423 sensory organ development
6.82 2.88e-03 GO:0043009 chordate embryonic development
6.49 4.66e-02 GO:0016337 cell-cell adhesion
6.07 2.29e-02 GO:0048598 embryonic morphogenesis
5.77 4.19e-05 GO:0009790 embryo development

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
Enrichment   P-value GO Accession GO Term
8.73 2.37e-02 GO:0045211 postsynaptic membrane
8.20 7.84e-03 GO:0030425 dendrite
6.41 3.00e-02 GO:0005667 transcription factor complex
5.39 9.76e-03 GO:0043005 neuron projection
3.13 9.64e-03 GO:0005887 integral to plasma membrane
3.07 1.18e-02 GO:0031226 intrinsic to plasma membrane
2.67 1.33e-03 GO:0044459 plasma membrane part

Gene overrepresentation in function category:

Showing 1 to 13 of 13 entries
Enrichment   P-value GO Accession GO Term
73.72 3.20e-02 GO:0042043 neurexin binding
45.54 3.76e-03 GO:0004970 ionotropic glutamate receptor activity
43.01 4.50e-03 GO:0005234 extracellular-glutamate-gated ion channel activity
27.65 1.76e-02 GO:0008066 glutamate receptor activity
11.11 4.76e-02 GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
6.89 2.36e-02 GO:0046982 protein heterodimerization activity
5.84 1.93e-02 GO:0016563 transcription activator activity
5.59 1.36e-05 GO:0043565 sequence-specific DNA binding
4.98 8.90e-07 GO:0001071 nucleic acid binding transcription factor activity
4.98 8.90e-07 GO:0003700 sequence-specific DNA binding transcription factor activity
4.89 1.20e-06 GO:0030528 transcription regulator activity
2.97 1.99e-05 GO:0003677 DNA binding
2.09 1.22e-02 GO:0003676 nucleic acid binding