Motif ID: NRF1.p2

Z-value: 6.358


Transcription factors associated with NRF1.p2:

Gene SymbolEntrez IDGene Name
NRF1 4899 nuclear respiratory factor 1



Activity profile for motif NRF1.p2.

activity profile for motif NRF1.p2


Sorted Z-values histogram for motif NRF1.p2

Sorted Z-values for motif NRF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NRF1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_33677798 15.210 NM_015475
FAM98A
family with sequence similarity 98, member A
chr16_+_27122796 9.051 NM_001145348
JMJD5
jumonji domain containing 5
chr20_-_57051231 8.570 NM_016045
SLMO2
slowmo homolog 2 (Drosophila)
chr1_+_32251988 7.904 NM_006559
KHDRBS1
KH domain containing, RNA binding, signal transduction associated 1
chr2_-_197499584 7.048 NM_024989
PGAP1
post-GPI attachment to proteins 1
chr14_+_22633728 6.884 C14orf119
chromosome 14 open reading frame 119
chr19_-_51097694 6.776 NM_001012643
MYPOP
Myb-related transcription factor, partner of profilin
chr16_+_88102305 6.445 NM_003119
NM_199367
SPG7

spastic paraplegia 7 (pure and complicated autosomal recessive)

chr14_-_22127954 5.958 NM_001344
DAD1
defender against cell death 1
chr22_+_22996749 5.933 NM_001145468
NM_015330
SPECC1L

sperm antigen with calponin homology and coiled-coil domains 1-like

chr2_+_190234369 5.881 NM_019048
ASNSD1
asparagine synthetase domain containing 1
chr2_+_254843 5.864 NM_001040649
NM_004300
NM_007099
ACP1


acid phosphatase 1, soluble


chr20_+_48781457 5.863 NM_032521
PARD6B
par-6 partitioning defective 6 homolog beta (C. elegans)
chr14_-_22127902 5.831 DAD1
defender against cell death 1
chr17_-_42924828 5.765 MRPL45P2
mitochondrial ribosomal protein L45 pseudogene 2
chr6_+_30142910 5.477 NM_021959
PPP1R11
protein phosphatase 1, regulatory (inhibitor) subunit 11
chr2_-_254742 5.382 SH3YL1
SH3 domain containing, Ysc84-like 1 (S. cerevisiae)
chr3_+_10132314 5.321 NM_018462
C3orf10
chromosome 3 open reading frame 10
chr17_-_24302597 5.236 NM_001033561
NM_020889
PHF12

PHD finger protein 12

chr2_+_100545827 4.921 NM_024065
PDCL3
phosducin-like 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 19 of 19 entries
Enrichment   P-value GO Accession GO Term
2.76 2.23e-02 GO:0006412 translation
2.32 3.30e-03 GO:0051276 chromosome organization
1.88 2.57e-02 GO:0007049 cell cycle
1.82 6.32e-05 GO:0010467 gene expression
1.78 6.46e-04 GO:0016070 RNA metabolic process
1.76 2.30e-05 GO:0090304 nucleic acid metabolic process
1.72 5.20e-03 GO:0034645 cellular macromolecule biosynthetic process
1.70 7.87e-03 GO:0009059 macromolecule biosynthetic process
1.66 3.11e-02 GO:0006996 organelle organization
1.64 2.38e-04 GO:0044267 cellular protein metabolic process
1.63 8.80e-05 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.59 1.30e-08 GO:0044260 cellular macromolecule metabolic process
1.50 1.58e-03 GO:0006807 nitrogen compound metabolic process
1.50 2.44e-03 GO:0034641 cellular nitrogen compound metabolic process
1.48 7.91e-07 GO:0043170 macromolecule metabolic process
1.48 1.08e-02 GO:0019538 protein metabolic process
1.33 3.71e-04 GO:0044237 cellular metabolic process
1.31 1.09e-03 GO:0044238 primary metabolic process
1.25 1.19e-02 GO:0008152 metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 16 of 16 entries
Enrichment   P-value GO Accession GO Term
3.40 2.53e-03 GO:0005819 spindle
2.06 1.23e-06 GO:0005654 nucleoplasm
1.81 9.30e-06 GO:0031981 nuclear lumen
1.68 6.95e-05 GO:0044428 nuclear part
1.67 5.45e-05 GO:0070013 intracellular organelle lumen
1.64 1.36e-04 GO:0043233 organelle lumen
1.63 1.54e-04 GO:0031974 membrane-enclosed lumen
1.53 1.77e-11 GO:0005634 nucleus
1.39 7.98e-06 GO:0044446 intracellular organelle part
1.38 9.09e-06 GO:0044422 organelle part
1.33 2.50e-10 GO:0043231 intracellular membrane-bounded organelle
1.33 2.95e-10 GO:0043227 membrane-bounded organelle
1.31 2.47e-12 GO:0043229 intracellular organelle
1.31 3.38e-12 GO:0043226 organelle
1.27 6.83e-15 GO:0044424 intracellular part
1.26 1.00e-14 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 5 of 5 entries
Enrichment   P-value GO Accession GO Term
2.46 3.85e-07 GO:0003723 RNA binding
1.67 1.65e-08 GO:0003676 nucleic acid binding
1.56 1.71e-03 GO:0003677 DNA binding
1.26 1.03e-03 GO:0005515 protein binding
1.12 4.07e-02 GO:0005488 binding