Motif ID: NKX3-1.p2

Z-value: 1.364


Transcription factors associated with NKX3-1.p2:

Gene SymbolEntrez IDGene Name
NKX3-1 4824 NK3 homeobox 1



Activity profile for motif NKX3-1.p2.

activity profile for motif NKX3-1.p2


Sorted Z-values histogram for motif NKX3-1.p2

Sorted Z-values for motif NKX3-1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX3-1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_+_21399132 3.372 NM_002170
 IFNA8
interferon, alpha 8
chr3_+_174598937 3.371 NM_014932
 NLGN1
neuroligin 1
chr7_+_94377145 3.028 NM_001166161
NM_001166162
NM_001166163
 PPP1R9A


protein phosphatase 1, regulatory (inhibitor) subunit 9A


chr6_+_132000134 3.005 NM_005021
 ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr22_+_38652555 2.799 GRAP2
GRB2-related adaptor protein 2
chr18_-_29273979 2.645 NM_001105528
 C18orf34
chromosome 18 open reading frame 34
chrX_+_99726445 2.091 NM_022144
 TNMD
tenomodulin
chr7_+_45899621 2.014


chr4_+_119174947 1.999 NM_004784
 NDST3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr3_-_121445831 1.752 NM_001168271
NM_153002
 GPR156

G protein-coupled receptor 156

chr1_-_3556420 1.702 NM_017818
 WDR8
WD repeat domain 8
chr5_+_147238466 1.622 NM_054023
 SCGB3A2
secretoglobin, family 3A, member 2
chr11_-_13474101 1.615 NM_000315
 PTH
parathyroid hormone
chr9_-_21177529 1.607 NM_021068
 IFNA4
interferon, alpha 4
chr3_-_99236520 1.604 NM_001105580
 GABRR3
gamma-aminobutyric acid (GABA) receptor, rho 3
chr11_+_89507465 1.572 NM_005467
 NAALAD2
N-acetylated alpha-linked acidic dipeptidase 2
chr12_-_5925658 1.568 NM_020373
 ANO2
anoctamin 2
chr2_-_104834344 1.551 LOC100506421
hypothetical LOC100506421
chr11_-_100505667 1.537 NM_000926
 PGR
progesterone receptor
chr7_+_86111155 1.510 NM_000840
 GRM3
glutamate receptor, metabotropic 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 8 of 8 entries
Enrichment   P-value GO Accession GO Term
63.08 7.99e-05 GO:0060338 regulation of type I interferon-mediated signaling pathway
30.54 1.55e-03 GO:0001959 regulation of cytokine-mediated signaling pathway
30.54 1.55e-03 GO:0060337 type I interferon-mediated signaling pathway
30.54 1.55e-03 GO:0071357 cellular response to type I interferon
30.05 1.66e-03 GO:0034340 response to type I interferon
30.05 1.66e-03 GO:0060759 regulation of response to cytokine stimulus
11.62 1.16e-02 GO:0071345 cellular response to cytokine stimulus
6.90 3.59e-02 GO:0050776 regulation of immune response

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
Enrichment   P-value GO Accession GO Term
177.37 2.12e-05 GO:0005132 interferon-alpha/beta receptor binding